Summary

Dietary sugars, encompassing both naturally occurring and added varieties, have become central to discussions of global health. Free sugars, including those in fruit juices and honey, and added sugars introduced during processing or preparation contribute substantially to total energy intake in many populations. High consumption of sugar-sweetened beverages, confectionery and processed foods is linked to a spectrum of adverse outcomes, from dental caries to obesity, type 2 diabetes and cardiovascular disease. Mechanistically, excessive monosaccharide and disaccharide intake can drive positive energy balance, induce hepatic de novo lipogenesis and perturb insulin sensitivity, while rapid glycaemic excursions may exacerbate oxidative stress and endothelial dysfunction. Public health bodies generally recommend limiting free or added sugars to under 10% of total energy, with more stringent targets of 5% for additional benefit. Policy measures such as reformulation targets, fiscal levies, front-of-pack labelling and educational campaigns have been deployed to curb intake. However, consumption patterns remain heterogeneous across age groups, socioeconomic strata and regions, underscoring the need for tailored, evidence-based interventions that balance nutritional adequacy, cultural preferences and industry engagement.

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Sugar Consumption and Health Implications publication trend

The graph below shows the total number of articles in sugar consumption and health implications across all publications each year (not limited to Nature Index journals).

Technical terms

Free sugars: All monosaccharides and disaccharides added to foods and those naturally present in honey, syrups, fruit juices and fruit juice concentrates.

Added sugars: Sugars introduced during food processing or preparation, excluding those that occur naturally in intact fruits, vegetables and dairy products.

Glycaemic variability: The degree of fluctuation in blood glucose concentrations over time, reflecting metabolic control and risk of complications.

Continuous glucose monitoring (CGM): A technique for real-time measurement of interstitial glucose levels, providing insight into daily glycaemic patterns.

References

  1. Effects of reducing free sugars on 24-hour glucose profiles and glycemic variability in subjects without diabetes. Frontiers in Nutrition (2023).
  2. High Added Sugars Intake among US Adults: Characteristics, Eating Occasions, and Top Sources, 2015–2018. Nutrients (2023).
  3. Canadian Free Sugar Intake and Modelling of a Reformulation Scenario. Foods (2023).

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