Traditional Herbal Medicine for Allergic Conditions

Summary

Traditional herbal medicine has been employed across numerous cultures for the prevention and treatment of allergic disorders, notably allergic rhinitis, asthma and atopic dermatitis. Key systems, including traditional Chinese medicine, Ayurveda and Kampo, deploy complex botanical formulae rich in polyphenols, alkaloids and terpenoids that exert anti-inflammatory and immunomodulatory effects. Active constituents may stabilise mast cells, inhibit Th2-driven cytokine production and reduce immunoglobulin E levels, thereby attenuating the hypersensitivity cascade. Recent advances have elucidated molecular pathways by which herbal extracts influence dendritic cell-mediated antigen presentation and innate immune cell recruitment, while novel delivery platforms address issues of solubility and bioavailability. As interest in integrative care grows, standardisation of herbal preparations, rigorous clinical evaluation and mechanistic studies are essential to translate traditional wisdom into evidence-based practice, with global implications for reducing reliance on conventional pharmacotherapy and its associated side-effects.

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Traditional Herbal Medicine for Allergic Conditions publication trend

The graph below shows the total number of articles in traditional herbal medicine for allergic conditions across all publications each year (not limited to Nature Index journals).

Technical terms

Allergic rhinitis: An IgE-mediated inflammation of the nasal mucosa induced by exposure to airborne allergens, characterised by sneezing, itching, congestion and rhinorrhoea.

Bioavailability: The proportion of an administered herbal constituent that reaches the systemic circulation in an active form.

Nanocarrier: A nanoscale delivery vehicle designed to improve solubility, stability and targeted distribution of herbal extracts.

Th2 cells: A subset of T helper lymphocytes that secrete interleukins such as IL-4, IL-5 and IL-13, driving allergic inflammation and IgE production.

References

  1. Exploiting the nanotechnological approaches for traditional Chinese medicine in childhood rhinitis: A review of future perspectives. Nanotechnology Reviews (2024).
  2. Potential effectiveness of Chinese herbal medicine Yu ping feng san for adult allergic rhinitis: a systematic review and meta-analysis of randomized controlled trials. BMC Complementary Medicine and Therapies (2017).
  3. Treatment of Early Allergic and Late Inflammatory Symptoms of Allergic Rhinitis with Petasites Hybridus Leaf Extract (Ze 339): Results of a Noninterventional Observational Study in Switzerland. Pharmaceuticals (2021).

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