Summary

A range of surgical techniques has evolved to address end-stage wrist arthrosis, spanning soft-tissue interposition, segmental excision and prosthetic replacement. Proximal row carpectomy (PRC) and its variants create a functional neo-joint by excising the scaphoid, lunate and triquetrum; four-corner arthrodesis stabilises midcarpal facets while preserving partial motion; and total wrist arthroplasty (TWA) offers an implant-based solution for diverse pathologies from rheumatoid arthritis to post-traumatic osteoarthritis. Contemporary TWA designs employ modular stems, advanced surface coatings and novel biomaterials to mitigate loosening and optimise joint kinematics. Outcome measures across these approaches emphasise pain relief, range of motion, grip strength, complication and revision rates, and patient-reported functional scores. Long-term data indicate that while fusion techniques deliver durable stability, they may restrict motion; conversely, arthroplasty preserves movement but carries risks of implant wear, loosening and potential revision. Recent advancements in interposition grafts, bioabsorbable and shape-memory alloy fixation, and pyrocarbon hemiarthroplasty have refined the balance between stability and mobility, enabling tailored interventions based on pathology and patient demand.

Research from Nature Portfolio

No recent Nature Portfolio content available.

Wrist Arthroplasty Techniques and Outcomes publication trend

The graph below shows the total number of articles in wrist arthroplasty techniques and outcomes across all publications each year (not limited to Nature Index journals).

Technical terms

Proximal row carpectomy (PRC): Surgical excision of the scaphoid, lunate and triquetrum to create a neo-joint between the capitate and radius.

Four-corner arthrodesis: Fusion of the capitate, lunate, triquetrum and hamate bones following scaphoid excision to stabilise the midcarpal joint.

Interposition arthroplasty: Reconstruction of a joint surface gap using soft-tissue grafts or biomaterials to preserve motion and cushion articulations.

Total wrist arthroplasty (TWA): Replacement of the radiocarpal joint with a prosthetic implant designed to restore movement and unload arthritic surfaces.

Scapholunate advanced collapse (SLAC) and scaphoid nonunion advanced collapse (SNAC): Patterns of degenerative wrist arthritis characterised by progressive cartilage loss secondary to ligament injury or scaphoid nonunion.

References

  1. Proximal row carpectomy with interposition arthroplasty using both capsular flap and acellular human dermal matrix. BMC Musculoskeletal Disorders (2024).
  2. Clinical efficacy of Ni-Ti memory alloy four-corner arthrodesis concentrator in the treatment of scaphoid nonunion advanced collapse: a follow-up of over 10 years.. Journal of Plastic Surgery and Hand Surgery (2024).
  3. Lunate-capitate arthrodesis for scaphoid nonunion: a comparative study. BMC Musculoskeletal Disorders (2024).
  4. Four-corner fusion method using a bioabsorbable plate for scapholunate advanced collapse and scaphoid nonunion advanced collapse wrists: a case series study. BMC Musculoskeletal Disorders (2020).

About these summaries

This Nature Research Intelligence Topic summary is created with the cited references and a large language model. We take care to ground generated text with facts, and have systems in place to gain human feedback on the overall quality of the process in line with our AI principles. We strive to create accurate and useful summaries for people unfamiliar with the research topic and that supports this goal. These pages are a beta release and will be updated as we learn how best to help people gain value from a research topic summary.

Nature Strategy Reports
Turn complex research questions into confident strategic decisions 

When you're under pressure to set direction, justify investment, or understand your competitive position, you need more than raw data — you need trusted insights you can act on.

  • Benchmark your performance against global peers using robust, methodologically sound analysis.

  • Combine quantitative metrics with qualitative expert insight to uncover strengths, gaps and emerging opportunities.

  • Gain tailored, decision-ready recommendations aligned to your strategic priorities.

Talk to us to learn more about our data dashboards and bespoke strategy reports.

Nature Masterclasses
Grow research skills, confidence and careers with training built for every stage of the research lifecycle.

Developed with Nature Portfolio journal Editors and internationally renowned experts. Discover three ways to learn:

  • Self-paced, online courses in convenient bite-sized units, covering key skills across scientific writing, publishing, grant writing, data analysis, and more.

  • Expert trainer-led workshops with hands-on exercises and real-time feedback across core research skills, delivered via interactive group sessions.

  • Editor-led workshops combining core principles in writing and publishing, personalised 1:1 feedback from Nature Portfolio Editors and hands-on exercises.

Explore course catalogues and workshop agendas, enquire about the options or request institutional pricing.