Medical Biochemistry and Metabolomics articles for Germany

Time frame: 1 June 2025 - 30 May 2026
Count: 120

Article ‘Count’ for Medical Biochemistry and Metabolomics.

Journal Count Share
1 1.00
Endolysosomal Impact of Elevated Ceramide Levels Revealed by Optical and Ultrastructural Nanoprobing 1.00
1 0.07
Circulating saturated fatty acids and incident chronic kidney disease: a meta-analysis of de-novo prospective cohort investigations 0.07
1 0.02
Genomics-informed drug-repurposing strategy identifies two therapeutic targets for preventing liver disease associated with metabolic dysfunction 0.02
1 0.18
Inactivation of Atp7b copper transporter in intestinal epithelial cells is associated with altered lipid processing and cell growth machinery independent from hepatic copper accumulation and severity of liver histology 0.18
2 1.08
Three‐Segment Protein Labeling Using a Highly Efficient and Cysteine‐Less Split Intein Identified with Computational Prediction of Aggregation Properties 0.75
Targeted Detection of Phospholipid Aldehydes in Living Cells by Oxime Ligation 0.33
1 0.06
Cross‐Sectional scpFDG/scp in Down Syndrome and Autosomal Dominant Alzheimer's Disease 0.06
1 0.03
DHODH as a targetable metabolic Achilles’ heel for chemotherapy-resistant B-ALL 0.03
1 0.60
Preclinical and first-in-human evidence of 4-hydroxybenzoic acid for mitochondrial COQ2 deficiency 0.60
2 0.16
ZNF395 Is a Hypoxia-Responsive Regulator of Mitochondrial Glutaminolysis in Clear Cell Renal Cell Carcinoma 0.05
PPARδ Orchestrates a Prometastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer 0.11
1 0.06
Tumor-produced ammonia is metabolized by regulatory T cells to further impede anti-tumor immunity 0.06
2 0.09
Mitochondrial metabolism regulates the immunogenic responsiveness of dendritic cells 0.03
Lack of PCK1 in hepatic stellate cells causes liver fibrosis by fueling tricarboxylic acid cycle and increasing glycolysis 0.06
1 0.33
Bifunctional nanodisc platforms for studies on self-assembly and amyloid fibrillation 0.33
1 0.29
Probing the ferredoxin:hydrogenase electron transfer complex by infrared difference spectroscopy 0.29
1 1.00
Role of Adipose Tissue Compartments for Cardiovascular Risk in Diabetes Endotypes. 1.00
4 1.94
Extrinsic lipids are absorbed and accumulate in colorectal cancer 1.00
Colorectal cancer in metabolic dysfunction-associated steatotic liver disease: an international Delphi consensus statement 0.03
Secondary bile acid production by gut bacteria promotes Western diet-associated colorectal cancer 0.81
Targeting Treg–fibroblast interaction to enhance immunotherapy in steatotic liver disease-related hepatocellular carcinoma 0.10
2 0.26
Statins halt polycystic liver disease by reprogramming metabolism and normalizing mitochondrial bioenergetics in cystic cholangiocytes. 0.04
Gut-to-Bile transfer of microbially amidated minor bile acids in patients with hepatopancreatobiliary disorders. 0.22
2 0.05
Semaglutide and Early-Stage Metabolic Abnormalities in Individuals With Schizophrenia Spectrum Disorders 0.03
Antipsychotic Drugs and Dysregulated Glucose Homeostasis 0.03
6 3.69
Prolyl-3-hydroxylase 1 is a central regulator of collagen post-translational modifications and the collagen biosynthetic network 0.61
The intrinsically disordered region of the human parathyroid hormone controls functional amyloid properties 1.00
Hepatic management of toxic sterols after acute deletion of Cyp51 from cholesterol synthesis 0.08
A farnesoid X receptor T296I variant disrupts ligand-induced FXR activation and thus bile acid transport in progressive familial intrahepatic cholestasis 1.00
The serine protease HTRA1 targets tau fibrils and provides a proteolytic barrier against pathogenic protein conformations 0.90
Characterization of Caenorhabditis elegans sphingomyelin synthases through heterologous expression 0.10
2 1.10
Systematic membrane thickness variation across cellular organelles revealed by cryo-ET 1.00
PEX14 acts as a molecular link between optineurin and the autophagic machinery to induce pexophagy 0.10
4 2.10
Cold-induced serum short-chain fatty acids act as markers of brown adipose tissue metabolism in humans 0.17
Serum Proteomics of Insulin Resistance Disorders Distinguish MASLD From Lipodystrophy and Insulin Receptor Defects 0.08
Reference Values for Serum Leptin Levels in Children, Adolescents, and Adults With Normal Weight, Overweight, and Obesity 0.85
Magnesium Depletion, Metabolic Impairment, and Cardiac Alterations: The NAKO-MRI Study with Mendelian Randomization 1.00
3 0.27
Redirection of sphingolipid metabolism drives cytoskeletal defects in SPLIS and reveals ROCK inhibition as therapy 0.08
SPNS1 variants cause multi-organ disease and implicate lysophospholipid transport as critical for mTOR-regulated lipid homeostasis 0.06
Neuraminidase 1 secondary deficiency contributes to CNS pathology in neurological mucopolysaccharidoses via brain proteins hypersialylation 0.13
1 0.03
Claudin-1 is a mediator and therapeutic target in primary sclerosing cholangitis 0.03
1 1.00
The endocrine product of renal (preglomerular) contractile pericytes depends on prolyl‐4‐hydroxylases 2 and 3 1.00
2 1.13
Structural Heterogeneity of Proteoform-Ligand Complexes in Adenosine Monophosphate-Activated Protein Kinase Uncovered by Integrated Top-Down Mass Spectrometry 0.13
The Structure of Human IAPP Fibrils Reflects Membrane and pH Conditions 1.00
1 0.05
Adiposity distribution and risks of 12 obesity-related cancers: a Mendelian randomization analysis 0.05
3 0.76
MEDAG functions as an A-kinase-anchoring protein in adipocytes 0.10
H4K16 acylations destabilize chromatin architecture and facilitate transcriptional response during metabolic perturbations 0.30
Mechanism of cotranslational protein N-myristoylation in human cells 0.36
2 1.13
Reconstruction of Molecular Interaction Patterns from Endolysosomes in Ceramide-Depleted Cells 1.00
Using DNA Origami to Study Nanoscale Organization of Plasma Membranes 0.13
5 1.76
A deep-learning framework reveals whole-body perturbations at cell level 0.84
Ubiquitination of glycogen and metabolites in cells and tissues 0.09
Nutrient requirements of organ-specific metastasis in breast cancer 0.02
Genetic suppression features as a Barth syndrome therapeutic target 0.04
Quantitative imaging of lipid transport in mammalian cells 0.78
5 1.67
Membrane bridges and nanodomain partitioning govern membrane protein targeting to lipid droplets 0.14
Palmitoylation-mediated regulation of KAT2A promotes lung metastasis in breast cancer 0.02
FSP1-mediated lipid droplet quality control prevents neutral lipid peroxidation and ferroptosis 0.13
Remote control of AMPK via extracellular adenosine controls tissue growth 1.00
PEX39 facilitates the peroxisomal import of PTS2-containing proteins 0.38
32 17.40
Direct observation of ATP-driven ubiquitin chain handling by Cdc48 0.38
Atomic structures of medin and Aβ fibrils reveal polymorphic remodeling in mixed amyloid systems 0.17
White adipose atrophy exacerbates cold stress and accelerates aging in male mice 0.06
Sphingosine-1-Phosphate-derived 2-Hexadecenal is a central mediator of ocular neovascularization by inhibiting Sphingosine-1-Phosphate receptor 5 0.79
An immunobiliary single-cell atlas resolves crosstalk between type 2 conventional dendritic cells and γδ T cells in cholangitis 0.98
Fluorescence-based mapping of condensate dielectric permittivity uncovers hydrophobicity-driven membrane interactions 0.78
The ribosome-associated N-terminal acetyltransferase B coordinates global proteostasis and autophagy in plants by creating Ac/N-degrons 0.67
SLIT3 fragments orchestrate neurovascular expansion and thermogenesis in brown adipose tissue 0.13
Engineering synthetic cells with intramembrane domains possessing distinct bilayer asymmetries 0.88
NAA40 and NAC cooperate in co-translational histone acetylation in humans 0.75
GPR146 in adipose tissue drives adipose-liver crosstalk and promotes hepatic steatosis in mice 0.05
NatA engages in multi-factor complexes at the ribosomal polypeptide tunnel exit 0.60
Lipedema World Alliance Delphi Consensus-Based Position Paper on the Definition and Management of Lipedema: Results from the 2023 Lipedema World Congress in Potsdam 0.33
The dorsal aortic compartment is a developmental source of brown adipose tissue in mice 0.92
CUL4A-DDB1-DCAF10 is an N-recognin for N-terminally acetylated Src kinases 1.00
AI-guided transition path sampling of lipid flip-flop and membrane nanoporation 1.00
Inhibition of adipocyte lipolysis by vaspin impairs thermoregulation in vivo 0.92
Cytochrome c oxidase dependent respiration is essential for T cell activation, proliferation and memory formation 0.06
Plasma membrane transbilayer asymmetry of PI(4,5)P2 drives unconventional secretion of Fibroblast Growth Factor 2 1.00
Avian GCGR-mediated continuous fat utilization offers perspectives for obesity treatment 0.05
Fructose and follistatin potentiate acute MASLD during complete hepatic insulin resistance 0.07
Desaturase-dependent secretory functions of hepatocyte-like cells control systemic lipid metabolism during starvation in Drosophila 0.50
Tumour sampling conditions perturb the metabolic landscape of clear cell renal cell carcinoma 0.21
Physics-based evolution of transmembrane helices reveals mechanisms of cholesterol attraction 0.50
Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling 0.17
UBE2J2 sensitizes the ERAD ubiquitination cascade to changes in membrane lipid saturation 1.00
Demethylation of methylguanidine by a stepwise dioxygenase and lyase reaction 1.00
MTCH2 modulates CPT1 activity to regulate lipid metabolism of adipocytes 0.17
Anle138b binds predominantly to the central cavity in lipidic Aβ₄₀ fibrils and modulates fibril formation 1.00
Uncovering the prevalence, key biogenesis enzymes, and biological significance of archaeal lipoproteins 0.14
Defective Olfactomedin-2 connects adipocyte dysfunction to obesity 0.14
Aging and diet alter the protein ubiquitylation landscape in the mouse brain 1.00
2 0.21
p53 inactivation drives breast cancer metastasis to the brain through SCD1 upregulation and increased fatty acid metabolism 0.10
Cytidine diphosphate diacylglycerol synthase 2 is a synthetic lethal target in mesenchymal-like cancers 0.11
2 1.05
Metabolic quiescence of naive-like memory T cells precedes and maintains antigen-specific T cell memory 1.00
Mitochondrial respiration is necessary for CD8 T cell proliferation and cell fate 0.05
1 0.26
Obesity due to MC4R deficiency is associated with reduced cholesterol, triglycerides and cardiovascular disease risk 0.26
1 0.19
Glucose hypometabolism and hyperphosphorylated Tau synergistically drive neuronal necroptosis 0.19
2 1.93
Individual lipid alterations at the origin of neuronal Ceramide Synthase defects. 1.00
Functional analysis of CYP4B1 enzymes from apes and humans uncovers evolutionary hot spots for adaptations of the catalytical function. 0.93
2 1.17
Evolutionary remodeling of a remnant GET pathway factor into PEX38, an essential peroxin 1.00
Cholesterol-containing lipid crystals can directly stiffen the rat steatotic liver before fibrosis 0.17
3 0.60
Ablation of Prdm16 and beige fat identity causes vascular remodeling and elevated blood pressure 0.05
Acidosis orchestrates adaptations of energy metabolism in tumors 0.50
Septal LYVE1+ macrophages control adipocyte stem cell adipogenic potential 0.05
8 4.52
Metabolic rewiring driven by phosphoglycolate phosphatase deletion inhibits ferroptosis 0.89
Adissp activates insulin-independent glucose disposal and energy expenditure in white fat to treat diabetes and cardiometabolic disease 0.08
Posttranscriptional reprogramming controls MASLD progression through chronic ER stress adaptation 0.29
Hemizygous loss of helicases promotes genomic instability and cancer development 0.15
How does Mycoplasma pneumoniae scavenge lipids from its host membranes? 1.00
Steric repulsion counteracts ER–to–lipid droplet protein movement 0.20
Linear ubiquitination prevents lipodystrophy and obesity-associated metabolic syndrome 0.91
A noncanonical role of glycolytic metabolites controlling the timing of mouse embryo segmentation 1.00
1 0.06
Retinal polyunsaturated fatty acid supplementation reverses aging-related vision decline in mice 0.06
1 0.09
Exposure to sugar rationing in first 1000 days after conception and long term cardiovascular outcomes: natural experiment study 0.09
2 1.13
NRAC controls CD36-mediated fatty acid uptake in adipocytes and lipid clearance in vivo. 0.91
Altering metabolism programs cell identity via NAD+-dependent deacetylation 0.23
3 0.27
Disparities in diabetes treatment and monitoring for people with and without mental disorders: a systematic review and meta-analysis 0.13
Metformin for overweight and obese children and adolescents with bipolar spectrum and related mood disorders treated with second-generation antipsychotics: a randomised, pragmatic trial 0.05
Mortality from respiratory diseases in individuals with severe mental illness: a large-scale systematic review and meta-analysis of pooled and specific diagnoses 0.09

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