Medical Biotechnology articles for Peking University (PKU), China

Time frame: 1 June 2025 - 30 May 2026

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Count: 93

Article ‘Count’ for Medical Biotechnology.

Journal Count Share
9 3.84
Optimization of Lipid Nanoparticles for Safe and Versatile Lung-Targeted RNA Delivery and Disease Therapy 0.60
Modular Functionalized Gates for Field-Effect Transistor Biosensors Enabling Reliable Detection of Trace miRNAs 0.18
Gravity-Driven Formation of Water-in-Wax Spheres for Efficient One-Pot CRISPR Diagnostics 0.03
Multi-Activity Nanozyme-Integrated Scaffolds: Harnessing Synergistic Enzyme-like Effects for Complete Treatment of Infected Bone Defects 0.50
Piezoelectric Nanofibers Synchronize Mitochondrial Dynamics and Immune Responses for Regeneration of Infected Wounds 1.00
Orbital Hybridized MoO3/MoSe2 Heterojunction for Dual-Driven Interfacial Reaction and Charge Transfer Toward Enhanced Electrochemical Response 0.08
An Aggrecanase-Responsive Delivery Hydrogel System of miRNA-17 Facilitates Microfracture-Mediated Articular Cartilage Regeneration by Reprogramming Hostile Inflammatory Niche 0.15
Flexible Mechanoporation Chips for High-Throughput Intracellular Delivery Based on Controlled Pneumatic Microvalve Array 0.95
Deciphering the Distinct Roles of Molecular and Supramolecular Chirality in Osteogenic Differentiation of Mesenchymal Stem Cells in 3D Hydrogels 0.33
5 3.54
Supramolecular dynamic hydrogels loaded with bevacizumab nanoparticles promote hyaline cartilage regeneration by inhibiting angiogenesis 0.23
Mitochondrial transfer through tunneling nanotubes inspires an innovative strategy for intercellular drug delivery 0.94
A viral infection-biomimetic strategy for Antibody-Guided Targeted Protein Degradation 0.67
Biodegradable Zn-xY alloys with enhanced osteogenesis and angiogenesis effects for bone implant applications 1.00
Biodegradable Zn-Li-Mn alloy to achieve optimal strength and ductility for bone implants 0.71
7 2.44
Multifunctional Hydrophilic Selenium-Polyurea for Controlled Ion Release of Biodegradable Alloys and Immuno-osteogenic Synergistic Modulation 0.83
Functionally Designed Liquid Crystal Elastomer Foams for Cartilage Regeneration 0.67
A Morinda Officinalis Extracellular Vesicles‐Encapsulated Redox Homeostasis Modulatory Hydrogel Promotes Growth Plate Injury Repair by Regulating the Oxidative Stress Microenvironment 0.08
Melanin‐derived Biomimetic Nanoparticles Improve Patency and Tissue Regeneration of Vascular Grafts via ROS Scavenging and Immunomodulation in an Atherosclerotic Rat Model 0.09
Multifunctional Nanoparticle Reinforced GelMA Hydrogel for Osteoporotic Pathophysiological Microenvironment Improvement and Bone Defect Regeneration 0.67
Biodegradable Polymeric Nanoparticle Employing a Photodynamic/Photothermal/Thermodynamic Combination Strategy for Treatment of Acute Maxillofacial Wound Infections 0.05
Label‐Free and Low‐Power Driven Cancer Biomarker Detection Enabled by 2D Hexagonal Titanium Oxide 0.05
14 5.37
A Dual-Targeting Strategy Against ROS and GSK-3β With a PEGylated Fullerene/Smart Hydrogel Synergistic System for Diabetic Bone Regeneration 0.49
N-Acetylcysteine–Mediated Surface Remodeling of Inhaled mRNA Lipid Nanoparticles Enables Coordinated Mucosal and Systemic Antitumor Immunity 0.30
Trace Detection of Multiple Macromolecular Biomarkers in Saliva by Enzymatic Responsive Serial‐Nanofluids Strategy 0.44
Fusion Peptide-Incorporated Lipid Nanoparticles Boost Endosomal Escape and Enhance Cytosolic mRNA Delivery 0.33
DNA Supramolecular Hydrogel Alters Exosomal microRNA Atlas and Paracrine Secretory Profile of MSCs to Promote Bone Remodeling and Ameliorate Osteoradionecrosis of the Jaw 0.14
Optimizing Peptide Ionizable Lipids Enables Efficient and Low-Toxicity mRNA Delivery for In Vivo Prime Editing and Protein Replacement Therapy 0.30
Bioinspired Engineering of Living Materials to Reconstruct Stromal-Parenchymal Interactions for Post-Stroke Neural Regeneration 0.16
Endogenous Metal Ion‐Enriched Immunostimulating Biomimetic Scaffold Improves In Situ Bone Regeneration 0.94
Metabolic Osteoimmune Biodegradable Zn–Mn Alloys: High Strength-Ductility and In Situ Vascular-Osteogenic Coupling 0.43
A Pseudo-Mytilus Edulis Foot Protein-Based Hydrogel Adhesive with Osteo-Vascular-Immune Coupling Effects for Osteoporotic Bone-Implant Integration 0.05
siAkt2‐Loaded Nanoparticles Reprogramming Macrophages to M2 Phenotype for Effective Bone Defect Repair 0.73
Calcium Phosphate Nanoparticle-Immobilized Macrophage-Derived Extracellular Vesicle Nanohybrid Facilitates Diabetic Bone Regeneration 0.88
Temporal Immunomodulatory Hydrogel Regulating the Immune-Osteogenic Cascade for Infected Bone Defects Regeneration 0.08
An Environmentally Responsive Molecular Engineering Framework for Subcellular Drug Translocalization 0.09
5 1.34
Aptamer-Mediated Proximity Labeling (ApMPL) for Spatially Resolved Deciphering of Cell Membrane Protein Interactomes 0.07
Wettability-Enhanced Photothermal Vertical Flow Biosensor on a Syringe for PSA Detection Using TaTe2 Nanosheets 0.11
One-Pot and Enzyme-Free Analysis of mRNA Vaccines Based on a Double Amplification System Featured by Adjustable Structure MNAzyme 0.05
A 3D Printed Meridian-Arrayed Microfluidic Device for Dual-Physical Fields Induced Highly Efficient Intracellular Delivery 0.10
Liquid-Phase Barrier Modified Nitrocellulose Membrane: A Strategy for Boosting Chemiluminescent Detection in Lateral Flow Assays 1.00
3 0.74
Remote Molecule Activation in Living Mice Triggered by Therapeutic Ultrasound 0.50
Stabilizing Cu3+ Active Center by Intramolecular Electron Transfer for Boosting Complete Glucose Electrooxidation 0.11
Synthesis of Chirally Chimeric Protein Nanoparticle Vaccines via Mirror‐Image Spy Chemistry 0.13
1 0.89
Interleukin-17B is a new biomarker of human muscle regeneration in dystrophinopathies 0.89
4 0.88
p53 safeguards chemical reprogramming of human somatic cells toward pluripotency 0.56
Fibroblast bioelectric signaling drives hair growth 0.02
A mechano-resistance mechanism in skin adapts to terrestrial locomotion 0.03
An alternate receptor for adeno-associated viruses 0.27
2 1.47
Perturb-seq uncovers pathological obstacles to direct cardiac reprogramming in vivo 0.78
Chemical reprogramming of human blood cells to pluripotent stem cells 0.69
1 0.17
A preliminary profile of RNA bound on the cell surface 0.17
1 0.57
ExposomeX: Development of an Integrative Exposomic Platform to Expedite Discovery of the “Exposure−Biology−Disease” Nexus 0.57
1 0.07
Bezeotermin Alfa (rhBMP-6) Administration in Lumbar Interbody Fusion Surgery Using a Posterior Approach 0.07
10 3.68
Diffusion-Mediated Synthesis of Durable High-Entropy Sulfide Nanocrystals: Le Chatelier-Driven and Electron Configuration Effects 0.03
Site-Specifically Modified Circular Ribonucleic Acid Serves as Multitarget miRNA Sponge with Low Immunogenicity 0.02
Bioinspired Diffusion-Limited Silicification in Coacervate Assemblies Enables Smart Nanotoroids for Deep and Sensitive Tumor Penetration 0.09
Safe and Highly Efficient Lipid-Pro-Dexamethasone Nanoparticles for mRNA Delivery and Base Editing 0.58
FAP-Synergistic Organ-Targeted mRNA-LNP for Overcoming Delivery Barriers in Hepatic and Pulmonary Fibrosis 0.84
Electrochemomics Profiling Metabolic Dynamics in Biofluids 0.16
Evolution of Cross-Linking Aptamers for Long-Lasting Membrane Protein Labeling 1.00
Hydrogen Bond-Assisted Two-Component Lipid Nanoparticles for Spleen-Specific mRNA Delivery 0.30
Targeted RNA Degradation via LipoSM-RiboTAC Nanoparticles: A Versatile Platform for Cancer Therapy 0.21
mRNA-Based FRET-FLIM Imaging Platform for Quantifying Lipid Nanoparticle Endosomal Escape and Membrane Damage 0.44
1 0.09
Associations between trajectories of plasma biomarkers for Alzheimer’s disease, brain structures, and cognitive function: a prospective cohort study in the UK Biobank 0.09
3 1.39
Evolution of Aptamer Materials Maps Exosomal Surface Proteins at the Nano–Bio Interface 0.95
Mass Spectrometry-Assisted High-Throughput Discovery of Lung-Specific Lipid Nanoparticles for In Vivo Protein Delivery 0.25
Nebulized Lipid Nanoparticles Deliver mRNA to the Liver for Treatment of Metabolic Diseases 0.19
1 0.73
A continuous totipotent-like cell-based embryo model recapitulates mouse embryogenesis from zygotic genome activation to gastrulation 0.73
13 4.42
4D metallic metamaterials for bone implants via biodegradation 0.60
Hepatic SNHG9 links gut microbiota to liver protection in drug-induced liver injury 0.09
Intelligence-responsive wettability switch coating on magnesium implants for treating osteoporotic fracture 0.12
Epitranscriptomic regulation of mRNA stability in pivotal transcription factors modulates the second cell fate decision 0.17
Reversible surface modifications of functional proteins for accelerated cytosolic delivery via cell-penetrating peptide clusters 0.08
Spatiotemporal interplay between epithelial and mesenchymal cells drives human dentinogenesis 0.16
Rapid endothelialization of printed vascular grafts by perivascular niche-circulating endothelial progenitors crosstalk 0.03
Lymphatic–stem cell crosstalk promotes tendon regeneration via Notch1–Srebp2–mediated cholesterol metabolism 0.80
Autocrine ECM molecules establish MSC quiescence during incisor development by disrupting WNT ligand trafficking process 0.24
Engineering of mRNA vaccine platform with reduced lipids and enhanced efficacy 0.05
Chemically modified tRNA enhances the translation capacity of mRNA rich in cognate codons 1.00
Space-confined synthesis of sinter-resistant high-entropy nanoparticle library 0.08
Cascade-heterogated proton nanotransistors for multiplex pH-interval imaging 1.00
1 0.23
Maternal factor OTX2 regulates human embryonic genome activation and early development 0.23
3 0.58
Peptide codes for organ-selective mRNA delivery 0.19
Tissue-specific mRNA delivery and prime editing with peptide–ionizable lipid nanoparticles 0.36
Albumin-recruiting lipid nanoparticle potentiates the safety and efficacy of mRNA vaccines by avoiding liver accumulation 0.03
4 1.10
Maternal IntS11 primes embryonic totipotency by organizing early zygotic transcription initiation 0.02
Charge-reversal proteolysis polymers enable tissue-specific STING degradation in rheumatoid arthritis 0.88
Cryo-EM structure of the Rift Valley fever virus envelope protein in complex with a potent neutralization antibody 0.17
Organoid-based neutralization assays reveal a distinctive profile of SARS-CoV-2 antibodies and recapitulate the real-world efficacy 0.04
4 0.89
Xenopus IgX informs engineering strategies of IgM and IgG hexamers 0.64
Spatiotemporally controlled delivery of biological effectors from nanofiber scaffolds accelerates skin wound healing in porcine models 0.11
Pressure-driven microinjection (PMI) of porous-coated balloon for ultrafast endoluminal drug delivery across biological barriers 0.13
Widespread presence of bone marrow–like hematopoietic stem cell niche in invertebrate skeletons 0.01

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