Medicinal and Biomolecular Chemistry articles for United Kingdom (UK)

Time frame: 1 June 2025 - 30 May 2026

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Count: 93

Article ‘Count’ for Medicinal and Biomolecular Chemistry.

Journal Count Share
2 1.08
The Liquid State of RIM1α and RBP Condensates is Maintained by Lipids 1.00
Biomimetic Ginsenoside Rb1 and Probucol Co-Assembled Nanoparticles for Targeted Atherosclerosis Therapy via Inhibition of Oxidative Stress, Inflammation, and Lipid Deposition 0.08
1 1.00
Nanopipettes Enable Native Mass Spectrometry Studies of the Intrinsically Disordered Protein α-Synuclein in Biochemical Buffers 1.00
3 1.54
Ferritin Iron Mineralisation: Route of Fe3+ Transfer From the Ferroxidase Centre to the Inner Cavity of Human H-Chain Ferritin 0.92
3-Deoxy-3-Fluoro Mannuronic Acid Alginates: Stereoselective Automated Synthesis and Conformational Behaviour 0.27
Cyclo‐Polyproline: Chameleonic All‐Peptide Macrocycles With Induced‐Fit Host‐Guest Recognition 0.35
8 5.02
Core-block engineering enables control of ice recrystallisation inhibition in polymer nanoparticles 1.00
Deciphering the molecular origin of the 19.3 eV electronic excitation energy of H3+ 0.10
Yeast [FeFe]-hydrogenase-like protein Nar1 binds a [2Fe–2S] cluster 0.22
Europium probe binding to serum albumin and αsub1/sub-AGP, key importance of configuration, charge and size complementarity 0.33
Macrocyclization of backbone iN/i-methylated peptides by a prolyl oligopeptidase with a distinctive substrate recognition mechanism 0.44
Design and characterisation of photoactivatable and lysine reactive io/i-nitrobenzyl alcohol-based crosslinkers 1.00
Synthesis and functionalization of vinyl sulfonimidamides and their potential as electrophilic warheads 1.00
Tandem-repeat proteins introduce tuneable properties to engineered biomolecular condensates 0.92
1 1.00
Disrupted hippocampal replay is associated with reduced offline map stabilization in an Alzheimer’s mouse model 1.00
4 2.13
P-bodies act as dynamic control hubs for RNA processing and storage 1.00
J-domain proteins cooperate with Hsp70 to drive multiphase separation of RNA-binding-deficient TDP-43 0.06
A glycine at position 105 leads to clavulanic acid and avibactam resistance in class A β-lactamases 0.07
A versatile fluorescence polarization based deubiquitination assay using an isopeptide bond substrate mimetic (IsoMim) 1.00
2 0.63
CDR2 is a dynein adaptor recruited by kinectin to regulate ER sheet organization 0.18
Pex30-dependent membrane contact sites maintain ER lipid homeostasis 0.44
1 0.02
Sulfite oxidase deficiency causes persulfidation loss and hydrogen sulfide release 0.02
6 2.98
Monooxygenase Activity of Indoleamine 2,3-Dioxygenase 0.97
Chemically Fueled, Active Droplets Prevent the Aging of Peptides into Amyloid-Like Fibers 0.20
On-Cell Saturation Transfer Difference NMR Spectroscopy on Ion Channels: Characterizing Negative Allosteric Modulator Binding Interactions of P2X7 0.80
A Charge-Driven Strategy for Covalent Modification and Modulation of Biomolecular Condensates 0.90
Selective Ion Binding and Uptake Shape the Microenvironment of Biomolecular Condensates 0.06
Controlling Multiphase Coacervate Wetting and Self-Organization by Interfacial Proteins 0.06
4 2.46
The ribosome synchronizes folding and assembly to promote oligomeric protein biogenesis 0.60
Transcriptome-wide mRNP condensation precedes stress granule formation and excludes new mRNAs 0.08
A structural basis for chaperone repression of stress signaling from the endoplasmic reticulum 0.78
VEL-dependent polymerization maintains the chromatin association of Polycomb proteins for the switch to epigenetic silencing 1.00
2 0.30
Geometric Confinement in Solid-State Nanopores Enables Single-Molecule Discrimination of Ferritin Subunits and Translocation Bias 0.08
Reprogramming Chirality in Peptide Self-Assembly via Intramolecular Side Chain-Backbone Hydrogen Bonding 0.21
3 0.86
Identification of an allosteric site on the E3 ligase adapter cereblon 0.16
Collective homeostasis of condensation-prone proteins via their mRNAs 0.60
Diffusing protein binders to intrinsically disordered proteins 0.10
2 0.43
Paraspeckle condensation is controlled via TDP-43 polymerization and linked to neuroprotection 0.40
Ca-driven PDIA6 biomolecular condensation ensures proinsulin folding 0.03
2 0.37
High-throughput ligand diversification to discover chemical inducers of proximity 0.09
NCBP1 stress signaling drives alternative S6K1 splicing inhibiting translation 0.29
25 13.37
The prokaryotic origins of the COMMD protein family involved in eukaryotic membrane trafficking 0.09
BromoCatch: a self-labelling tag platform for protein modification and live cell imaging 1.00
A framework for the exploration of subcellular compartmentalization of RNA-binding proteins 0.03
The schizophrenia associated protein DISC1 forms a multivalent tetrameric hub via conserved UVR dimers 0.71
Protein coacervation-driven active forces power protocell dynamics 0.20
Optically driven control of mechanochemistry and fusion dynamics of biomolecular condensates via thymine dimerization 0.07
An intrinsically disordered region mediates RNA-binding selectivity and cellular activities of LARP6 0.79
Reduction of RAD23A extends lifespan and mitigates pathology in a mouse model of TDP-43 proteinopathy 0.12
Lucerastat, an oral therapy for Fabry disease: results from a pivotal randomized phase 3 study and its open-label extension 0.09
Simultaneous and sensitive quantification of protein and low molecular weight persulfides, polysulfides and H2S in biological samples 1.00
A BRET biosensor for measuring uncompetitive engagement of PRMT5 complexes in cells 0.53
Multiplex neurodegeneration proteotoxicity platform reveals DNAJB6 promotes non-toxic FUS condensate gelation and inhibits neurotoxicity 0.43
GroEL/ES chaperonin unfolds then encapsulates a nascent protein on the ribosome 1.00
Determination of key functional structures of an amorphous VHL-based SMARCA2 PROTAC 0.14
Enhanced hybridization-proximity labeling discovers protein interactomes of single RNA molecules 1.00
Charged peptides enriched in aromatic residues decelerate condensate ageing driven by cross--sheet formation 0.50
Quantifying collective interactions in biomolecular phase separation 0.56
Iron-sulfur clusters in SARS-CoV-2 exoribonuclease and methyltransferase complexes: relevance for viral genome proofreading and capping 0.17
Collagen VI microfibril structure reveals mechanism for molecular assembly and clustering of inherited pathogenic mutations 1.00
Universal peptide synthesis via solid-phase methods fused with chemputation 1.00
mRNA trafficking directs cell-size-scaling of mitochondria distribution and function 1.00
Coupling chromosome organization to genome segregation in Archaea 0.78
Thio-NHS esters are non-innocent protein acylating reagents 1.00
Connexin43 hemichannel blockade turns microglia neuroprotective and mitigates cognitive deficits in a mouse model of amyloidosis 0.02
Injectable magnesium-bisphosphonate MOF-based bone adhesive prevents excessive fibrosis for osteoporotic fracture repair 0.14
1 0.11
Effects of volenrelaxin in worsening heart failure with preserved ejection fraction: a phase 2 randomized trial 0.11
1 1.00
The local mechanostructural properties of protein cargoes regulate nucleocytoplasmic transport 1.00
4 2.83
Structural basis for recognition of diverse localizing mRNAs by Egl–BicD 1.00
Phosphorylation-dependent tuning of mRNA deadenylation rates 0.71
A small molecule stabilizer rescues the surface expression of nearly all missense variants in a GPCR 0.13
The human ribosome modulates multidomain protein biogenesis by delaying cotranslational domain docking 1.00
1 0.40
Water-based coupling of amino acids for sustainable solid-phase peptide synthesis 0.40
2 1.08
A Sequential Iodination–Fluorodeiodination of the Cubane Scaffold 0.08
The Baeyer–Villiger Oxidation of Cubyl Ketones: A Synthetic Route to Functionalized Cubanols 1.00
1 0.27
HAPLN2 forms aggregates and promotes microglial inflammation during brain aging in mice 0.27
1 0.73
Tissue-specific consequences of tag fusions on protein expression in transgenic mice. 0.73
1 0.26
Torsion-Driven Plectoneme Formation During Nanopore Translocation of DNA Polymers 0.26
6 3.27
The α-synuclein proteostasis network and its translational applications in Parkinson’s disease 1.00
Cystathionine γ-lyase is a major regulator of cognitive function through neurotrophin signaling and neurogenesis 0.03
Arg–Tyr cation–π interactions drive phase separation and β-sheet assembly in native spider dragline silk 0.07
Versatile NTP recognition and domain fusions expand the functional repertoire of the ParB-CTPase fold beyond chromosome segregation 1.00
Employing deep mutational scanning in the Escherichia coli periplasm to decode the thermodynamic landscape for amyloid formation 1.00
The RRM domain–containing protein Rbp3 interacts with ribosomes and the 3’ ends of mRNAs encoding photosynthesis proteins 0.17
1 0.01
Identification of Biological Subtypes of Friedreich Ataxia with Structural MRI-based Machine Learning. 0.01
2 0.21
Short RNA chaperones promote aggregation-resistant TDP-43 conformers to mitigate neurodegeneration 0.07
Design of intrinsically disordered region binding proteins 0.14
3 1.23
Structural remodeling of the mitochondrial protein biogenesis machinery under proteostatic stress 0.13
An alternative cytoplasmic SFPQ isoform with reduced phase separation potential is up-regulated in ALS 0.85
Massively parallel genetic perturbation suggests the energetic structure of an amyloid-β transition state 0.25
2 1.74
Phosphorylation tunes strain-specific protein condensation during rotavirus replication organelle assembly 0.92
RABGAP1 is a sensor that facilitates the sorting and processing of amyloid precursor protein. 0.82
1 0.11
Infrared Spectra of the Thymidine 13C2 and 13C4 Isotopes in H2O and D2O 0.11

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