Pharmacology and Pharmaceutical Sciences articles for United Kingdom (UK)

Time frame: 1 June 2025 - 30 May 2026

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Count: 142

Article ‘Count’ for Pharmacology and Pharmaceutical Sciences.

Journal Count Share
8 2.92
Bionano Interface Optimization for Rational Lateral Flow Assay Development 0.80
Zwitterionic Lipid Nanotherapeutics from Mulberry for Oral Treatment of Diabetic Colitis 0.10
The Impact of Polyethylene Glycol Lipid Anchors on the Physicochemical Properties, Protein Corona, Function, and Biodistribution of Lipid Nanoparticles 0.03
Utilizing Constrained Bicyclic Peptides for In Vitro Diagnostics 0.50
Dynamic Covalent Dual Prodrug Assemblies for Endometritis Therapy via Inflammation Alleviation, Tissue Repair, and Reproductive Function Restoration 0.06
Assembling Lipid Membrane Scaffolds on Microgel-Based Artificial Cells through Vesicle Fusion onto the Hydrogel Network 0.78
Optimizing Exosome Lipid Hybrid Nanoparticles for Enhanced siRNA Delivery and Improved Therapeutic Anticancer Efficacy In Vivo 0.63
Trafficking Glycogen Nanoparticles through Lymph Node Tissues for the Delivery of Small and Large Bioactive Molecules 0.03
1 0.88
Deciphering Small Molecule Diffusion Parameters Across Light Responsive Polymersome Membranes 0.88
1 0.80
Vascularized and Perfusable Human Heart‐on‐a‐Chip Model Recapitulates Aspects of Myocardial Ischemia and Enables Analysis of Nanomedicine Delivery 0.80
4 1.64
Evaluating Antibody Quality via Simultaneous Size and Charge Measurement with Single Protein Oscillators 0.31
Advanced Quality and Comparability Assessment of mRNA-Loaded Lipid Nanoparticles: Absolute Size Distribution Profiles and Structure from AF4-Coupled Light and X-ray Scattering Measurements 0.05
Observing Interactions between Lipopolysaccharide Aggregates and a Monoclonal Antibody Using Differential Fluorination and 19F NMR 1.00
Multiple Exposures of Plasma to Nanoparticles: A Novel Tool to Personalize Biomolecular Coronas and Fractionate Fluids 0.29
7 1.83
Programmable Coacervate–Membrane Interactions Direct Internal and Collective Organization in Membranized Protocells 0.08
Proteasome Cap Targeting Chimeras for Ubiquitination-Independent Targeted Protein Degradation 0.13
Caylobolide B: Structure Revision, Total Synthesis, Biological Characterization, and Discovery of New Analogues 0.60
On the Nature of Improper Hydrogen Bonding in RCH2F and RCHF2 Motifs 0.63
Heteromultivalent Nanogels as Highly Potent Inhibitors of Pseudomonas Aeruginosa 0.11
Flow‐Enabled, Modular Access to α,α‐Difluoromethylene Amines 0.17
New Transferrin Receptor‐Targeting Conjugate Effectively Delivers DNA to Mouse Brain 0.11
1 0.11
Improvements in Cardiometabolic Risk Factors by Weight Reduction: A Post Hoc Analysis of Adults With Obesity Randomly Assigned to Tirzepatide. 0.11
1 0.93
Exenatide Once Weekly in the Treatment of Patients with Multiple System Atrophy 0.93
2 1.09
Prescribing of Medication to Prevent Glucocorticoid Harms in Patients With Polymyalgia Rheumatica: A Cross‐Sectional Study and Two Emulated Target Trials in the Clinical Practice Research Datalink Aurum 1.00
Defining Optimally Safe and Effective Blood Levels of Hydroxychloroquine in Lupus: An Important Step toward Precision Drug Monitoring 0.09
2 1.08
Analog of prolactin-releasing peptide reduces body weight primarily through sustained fatty acid oxidation rather than hypophagia 0.43
Glucose-dependent insulinotropic polypeptide receptor signaling in oligodendrocytes increases the weight-loss action of GLP-1R agonism 0.65
1 0.67
Metabolite-induced DNA damage drives stochastic stem cell loss and clonal hematopoiesis 0.67
1 1.00
Structure revision of meroterpenoid natural products enabled by biomimetic total synthesis 1.00
10 6.91
DP5 without DFT: uncertainty-calibrated graph neural net accelerates structure confirmation via NMR 1.00
CBL ubiquitin ligase targets translation as a degrader E3 1.00
Structure–activity relationships can be directly extracted from high-throughput crystallographic evaluation of fragment elaborations in crude reaction mixtures 0.96
Towards automatically verifying chemical structures: the powerful combination of 1H NMR and IR spectroscopy 0.43
Maleic anhydride derived diphosphines: adaptable chelators for receptor-targeted 99mTc, 64Cu and 188Re radiotracers 0.88
Design, modular synthesis and screening of 58 shape-diverse 3-D fragments 0.94
Fully dissolved glucose-responsive insulin delivery system based on a self-immolative insulin prodrug and glucose oxidase 0.04
The development of sulfonated terpyridine ligands for control of regioselectivity in palladium-catalysed fluorination of anilides 1.00
A BODIPY-tagged trivalent glycocluster for receptor-targeting fluorescence imaging of live cells 0.06
High-throughput encapsulated nanodroplet screening for accelerated co-crystal discovery 0.60
4 0.31
Direct Oral Challenge for Penicillin Allergy: The International Network of Antibiotic Allergy Nations (iNAAN) Study 0.02
Direct Oral Challenge for Penicillin Allergy: A Hospital Implementation Evaluation Via the International Network of Antibiotic Allergy Nations (iNAAN) Study 0.02
Transplacental Transfer of Lumefantrine, Mefloquine, and Piperaquine: A Comparison of Concentrations in Mothers, Neonates, and Cord Blood 0.23
Evaluating the Use of Lower Dose Flucytosine for the Treatment of Cryptococcal Meningitis: A Clinical Trial 0.04
1 0.13
Ivermectin for Critically and Noncritically Ill Hospitalized Patients With COVID-19: Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community-Acquired Pneumonia (REMAP-CAP). 0.13
1 0.06
Risk of Thyroid Tumors With GLP-1 Receptor Agonists: A Retrospective Cohort Study. 0.06
2 0.30
Predictors, Sources, and Health Risks of Environmental Antibiotic Exposure in Chinese Pregnant Women 0.05
Human exposure to organophosphate esters (OPEs): A comparison between home and school microenvironments and inter-individual variations 0.25
2 0.15
Volatile organic compounds exposure and all health outcomes: An umbrella review and evidence map 0.03
HBM4EU e-waste study – Occupational exposure assessment to chromium, cadmium, mercury and lead during e-waste recycling 0.12
1 0.06
Acrylamide Exposure and Type 2 Diabetes in a Prospective Cohort Study of Chinese Adults: Association, Mediation, and Gene–Environment Interaction 0.06
3 0.24
Glucagon-like peptide-1 receptor agonists reduce experimental atherosclerosis progression, inflammatory biomarkers and cardiovascular events, irrespective of hyperglycaemia and obesity 0.03
GLP-1R agonists and heart failure: novel beneficial effects suggested by Mendelian randomization 0.03
Cardiac transthyretin amyloidosis treatment improves outcomes after aortic valve replacement for severe stenosis 0.19
1 0.14
Amino-Functionalized Zn(II)-Based Trilinker Metal–Organic Frameworks Conjugated with Folic Acid for Targeted Delivery of Doxorubicin on the MCF‑7 Cell Line of Human Breast Cancer 0.14
1 1.00
Structured tools for assessing quality and risk of bias in Mendelian randomization studies: an updated systematic review 1.00
1 0.01
Effectiveness of Colchicine for the Treatment of Long COVID 0.01
2 0.47
GH001 vs Placebo in Patients With Treatment-Resistant Depression 0.05
Genetic and Phenotypic Associations With Sustained Antidepressant Use in Major Depressive Disorder 0.42
2 1.63
Co-solute Effects Reveal the Nature of Weak Forces Governing GLP-1 Oligomers Stability 0.88
Receptor activity–modifying protein 3 enhances GLP-1-mediated insulin secretion 0.75
1 0.15
Diazoxide Choline Extended-release Tablets in Prader-Willi Syndrome: A Randomized, Double-blind, Withdrawal Period Study 0.15
1 0.21
β-cell Gɑs signaling is critical for physiological and pharmacological enhancement of insulin secretion 0.21
2 0.22
Evaluation of Immunization Route in Induction of Vaccine-Mediated Anti-Gonococcal Immune Responses in a Murine Model of Ascending Infection 0.19
Fetal Defects in Mice Treated with Integrase Strand Transfer Inhibitors: Comparison of Dolutegravir, Raltegravir, Bictegravir and Cabotegravir 0.03
1 1.00
Abcc1 deficiency protects from corticosterone but not cortisol-induced adiposity and insulin resistance in a sex-specific manner 1.00
9 5.94
Regio- and Stereoselective Deprotonation and Functionalization of Strained 1-Aza[n.1.0]bicycles 1.00
When Reality Defies Prediction: Polymorphism, Twinning, and Accordion Crystals 0.97
Controlled Self-Immolative Release of β-Lapachone via an Optimized para-Hydroxybenzyl Linker for Targeted Pancreatic Cancer Therapy 0.58
Fast and Reliable NMR-Based Fragment Scoring for Drug Discovery 0.60
Indolequinone-Based Hypoxia-Activated Proteolysis Targeting Chimeras Selectively Degrade BRD4 in Hypoxic Cancer Cells 0.90
Crystallizing the Uncrystallizable: Insights from Extensive Screening of PROTACs 1.00
Amorphization-Induced Electronic Modulation of Gd(OH)3 Nanocages with Enhanced Enzymatic Activities for Antitumor Therapy 0.08
Identification of Actionable Targeted Protein Degradation Effector Sites through Site-Specific Ligand Incorporation-Induced Proximity (SLIP) 0.79
The Binding Affinities of Serum Proteins to Nanoparticles 0.03
3 1.09
Extension Reports in Clinical Trials 0.06
Effect of Aficamten vs Metoprolol on Patient-Reported Health Status in Obstructive Hypertrophic Cardiomyopathy 0.03
Electromechanically Optimized Right Ventricular Pacing for Obstructive Hypertrophic Cardiomyopathy (EMORI-HCM) 1.00
1 0.08
Polypharmacy's Association With Mortality: Confounding From Underlying Morbidity 0.08
1 0.06
A predictive model for life-threatening fluoropyrimidine toxicity based on DPYD sequencing in colorectal cancer 0.06
1 0.08
Zigakibart demonstrates clinical safety and efficacy in a Phase 1/2 trial of healthy volunteers and patients with IgA nephropathy 0.08
2 1.17
Coupled Thermal–Chemical Stimuli in Hydrogel Swelling: A Multifield Kinetic Model for Dual-Responsive Hydrogel 0.17
The Effect of pH during Fabrication of Platinum-Containing Polymeric Arsenical Hydrogels 1.00
4 0.72
A five-year risk prediction model of cardiovascular disease in individuals with bipolar disorder: a nationwide register study from Sweden 0.04
Genome-wide meta-analyses of non-response to antidepressants provide insights into underlying molecular genetics and suggest potential pharmacotherapies 0.10
The dietary ligands, omega-3 fatty acid endocannabinoids and short-chain fatty acids prevent cytokine-induced reduction of human hippocampal neurogenesis and alter the expression of genes involved in neuroinflammation and neuroplasticity 0.55
DNA methylation profiles of long-term cannabis users in midlife: a comprehensive evaluation of published cannabis-associated methylation markers in a representative cohort 0.04
1 0.05
A skin-permeable polymer for non-invasive transdermal insulin delivery 0.05
1 0.67
Dual E3 ligase recruitment by monovalent degraders for tunable SMARCA 2/4 degradation 0.67
2 1.83
Degradation of G-quadruplex-binding proteins in chromatin using G4-ligand-based proteolysis-targeting chimeras 1.00
Hetero[3.1.1]propellanes 0.83
22 13.69
The benchmarking and application of tag-degraders in vivo to validate therapeutic targets 0.06
Cryo-EM structures of the CDK11-cyclin L-SAP30BP complex reveal mechanisms of CDK11 regulation 1.00
Accelerated drug development using a digital formulator and a self-driving tableting data factory 0.71
A dihydrouracil CRBN ligand mitigates IMiD associated safety liabilities in heterobifunctional targeted protein degrader 0.73
Counting cells can accurately predict small-molecule bioactivity benchmarks 0.17
Reliable repurposing of the antibody interactome inside the cell 0.53
Granzyme B-mimetic nanozyme for nanovesicle targeted anticancer applications 0.11
Phase diagrams of pharmaceutical solvates from mechanochemistry 0.83
GLP-1R associates with VAPB and SPHKAP at ERMCSs to regulate β-cell mitochondrial remodelling and function 0.71
MAASTY: a (dis)ordered copolymer for structural determination of human membrane proteins in native nanodiscs 0.20
Temporal trends in evidence supporting novel drug target discovery 1.00
Kinetically controlled hetero-fusion is a systems-level behaviour of polymer nanoparticle populations 1.00
State-selective small molecule degraders that preferentially remove aggregates and oligomers 1.00
Mode of action of a DCAF16-recruiting targeted glue that can selectively degrade BRD9 1.00
Systematic metaproteomics mapping reveals functional and ecological landscapes of Ex vivo human gut microbiota responses to therapeutic drugs 0.08
Discovery of a CNS active GSK3 degrader using orthogonally reactive linker screening 1.00
Development of a genetic priority score to predict drug side effects using human genetic evidence 0.17
Frustration in the protein-protein interface plays a central role in the cooperativity of PROTAC ternary complexes 0.26
Predictive design of crystallographic chiral separation 0.46
Accelerating fragment-based drug discovery using grand canonical nonequilibrium candidate Monte Carlo 1.00
Identification of nanomolar adenosine A2A receptor ligands using reinforcement learning and structure-based drug design 0.96
Combinatorial discovery of microtopographical landscapes that resist biofilm formation through quorum sensing mediated autolubrication 0.71
5 2.32
Orforglipron for maintenance of body weight reduction: the double-blind, randomized phase 3b ATTAIN-MAINTAIN trial 0.04
Multinational validation of the PREVENT and SCORE2 cardiovascular risk equations across 6.4 million individuals 0.13
Liraglutide in mild to moderate Alzheimer’s disease: a phase 2b clinical trial 0.96
Lifetime Benefits of Comprehensive Medical Therapy in Heart Failure with Mildly Reduced or Preserved Ejection Fraction 0.19
Effect of naltrexone pretreatment on ketamine-induced glutamatergic activity and symptoms of depression: a randomized crossover study 1.00
1 0.17
Special Report: Recommendations on Screening for Hydroxychloroquine Retinopathy (2026 Revision) 0.17
2 0.84
The benefits and risks of maternal RSV vaccination on mortality in South Africa: A modeling study 0.69
Pediatric studies and labeling additions required by the U.S. FDA for novel drugs approved from 2011 to 2023: A retrospective cohort study 0.14
1 0.18
From sequence to scaffold: Computational design of protein nanoparticle vaccines from AlphaFold2-predicted building blocks 0.18
1 0.86
Assessing Drug-mediated Inhibition of Liver Transporter Function with MRI: A First-in-Human Study. 0.86
1 1.00
Structural basis of T-loop–independent recognition and activation of CDKs by the CDK-activating kinase 1.00
3 1.10
The allosteric landscape of the Src kinase 0.31
In vivo functional profiling and structural characterization of the human GLP1R A316T variant 0.68
Padlock-designed MOFs triggers an “avalanche effect” to enhance apoptosis and suppress metastasis in central nervous system lymphoma 0.11
1 1.00
Core-shell microcapsules compatible with routine injection enable prime/boost immunization against malaria with a single shot 1.00
1 0.06
Long term use of proton pump inhibitors and risk of stomach cancer: population based case-control study in five Nordic countries 0.06
1 0.14
Coupled Orientational Disorder and Hydrogen-Bond Destabilization Drive Anisotropic Surface Melting in Curcumin Polymorphs 0.14
3 1.03
Efficacy and safety of rocatinlimab for the treatment of moderate-to-severe atopic dermatitis in ROCKET-IGNITE and ROCKET-HORIZON: two global, double-blind, placebo-controlled, randomised phase 3 clinical trials 0.09
Semaglutide and cardiovascular outcomes by baseline and changes in adiposity measurements: a prespecified analysis of the SELECT trial 0.10
The effects of antidepressants on cardiometabolic and other physiological parameters: a systematic review and network meta-analysis 0.84
1 0.11
Adverse drug reaction reporting with the Med Safety app in Uganda: a cluster-randomised, controlled trial 0.11
1 0.33
Oral contraceptive use and risk of liver cancer: a population-based study, systematic review, and meta-analysis 0.33
3 1.12
Association between GLP-1 receptor agonist use and worsening mental illness in people with depression and anxiety in Sweden: a national cohort study 0.08
The efficacy and safety of cannabinoids for the treatment of mental disorders and substance use disorders: a systematic review and meta-analysis 0.08
Pramipexole augmentation for the acute phase of treatment-resistant, unipolar depression: a placebo-controlled, double-blind, randomised trial in the UK 0.96
4 0.45
A Placebo-Controlled Trial of the Oral PCSK9 Inhibitor Enlicitide 0.07
Trial of High-Dose Oral Rifampin in Adults with Tuberculous Meningitis 0.05
Ciprofloxacin versus Aminoglycoside–Ciprofloxacin for Bubonic Plague 0.31
Ivermectin to Control Malaria — A Cluster-Randomized Trial 0.02
1 1.00
Assessment of macrolide resistance in the respiratory tract of preterm-born infants during treatment with azithromycin in the AZTEC clinical trial 1.00

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