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The Assessing Genetic Diversity in Africa (AGenDA) project shares their processes, including community engagement, obtaining ethics approvals, navigating legal compliance and developing a common governance framework.
Recent studies integrating multi-omics data with cell atlases across development for brains of humans and model organisms are revealing conserved and divergent patterns of brain development at the molecular and cellular levels, and linking these to complex behavioural and neuropsychiatric phenotypes.
The rise of green industrial policy is transforming decarbonization efforts; the implications for policymaking and global spillovers are discussed, as well as research needs.
The Biodiversity Cell Atlas aims to create comprehensive single-cell molecular atlases across the eukaryotic tree of life, which will be phylogenetically informed, rely on high-quality genomes and use shared standards to facilitate comparisons across species.
Next-generation batteries will present different risks to conventional lithium-ion cells, emphasizing the need for efforts towards characterizing the abuse tolerance and hazards associated with next-generation battery materials over their life cycle and providing the data in the context of supporting affected professionals.
The ‘science fiction science’ method simulates future technologies and collects quantitative data on the attitudes and behaviours of participants in various future scenarios, with the aim of predicting impacts of future technologies before they arrive.
Actionable research recommendations are outlined to improve the monitoring and modelling of forest resources and their carbon sink, and to better inform forest management decisions and the European Green Deal.
A strategy to improve the implementation of nature-based climate solutions in global forests for climate mitigation is described, comprising four key components to highlight notable science and policy considerations and providing solutions to improve rigour.
The Somatic Mosaicism across Human Tissues Network aims to create a reference catalogue of somatic mosaicism across different tissues and cells within individuals.
A transparent and reproducible scientific framework is introduced to formalize how trillions in economic losses are attributable to the extreme heat caused by emissions from fossil fuel companies, which could inform climate liability claims.
The development of multimodal foundation models, pretrained on diverse omics datasets, to unravel the intricate complexities of molecular cell biology is envisioned.
This Perspective offers a guide for researchers, peer-reviewed journals and funding agencies to make quantitative intersectional approaches a standard part of science and technology research design, where relevant, in efforts to enhance precision in science, and ultimately global equity and environmental sustainability.
This Perspective describes how recent advances in artificial intelligence could be used to automate medical image interpretation to complement human expertise and empower physicians and patients.
The standard approach of climate science is showing signs of a crisis owing to the emergence of discrepancies and disruptions in recent years; this Perspective discusses the policy implications and the paths forward.
This Perspective considers the application to infectious disease modelling of AI systems that combine machine learning, computational statistics, information retrieval and data science.
This Perspective discusses strategies and challenges for the Molecular Phenotypes of Null Alleles in Cells (MorPhiC) Consortium as it aims to catalogue the molecular and cellular phenotypes associated with null alleles of all human genes.
