Human metapneumovirus (hMPV) can cause severe acute respiratory illness in children but effective therapeutic monoclonal antibodies require further exploration. The authors here isolate a panel of monoclonal antibodies from children previously infected with hMPV, test their in vitro neutralizing potency, reveal their cryo-EM structures and manifest their in vivo prophylactic efficacy.
- Ahmed Magdy Khalil
- Behrouz Ghazi Esfahani
- Jarrod J. Mousa
