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Scientific Reports (26)
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Showing 1–50 of 80 results

Advanced filters: Author: Baojun Li Clear advanced filters

PD-1 blockade plus tyrosine kinase inhibitor remodels the tumor microenvironment in advanced renal cell carcinoma

Tyrosine kinase inhibitors (TKIs) combined with immunotherapy have improved outcomes in advanced renal cell carcinoma (aRCC), yet resistance persists. This group presents single-cell transcriptomic profiling of aRCC patients treated with TKIs and immune checkpoint inhibitors, uncovering an immunosuppressive microenvironment linked to therapeutic resistance.

Liangyou Gu
Qi Zhang
Baojun Wang
ResearchOpen Access31 Mar 2026
Nature Communications

P: 1-21
Linguistic dynamics of online scam conversations: a multi-stage analysis based on the COLD framework

Danyang Li
Ruilin Zheng
Li Crystal Jiang
ResearchOpen Access27 Mar 2026
Humanities and Social Sciences Communications

P: 1-12
Dual spillover of carbon monoxide and hydrogen initiates tandem urea electrosynthesis

Here the authors engineer dual spillover of H* and CO* on PdHx/Cu to enhance urea electrosynthesis, where CO* spillover from PdHx surface to Cu facilitates initial C–N coupling while H* spillover from PdHx lattice to Cu promotes C–N intermediate protonation.

Yuefei Li
Bingying Han
Jiayuan Li
ResearchOpen Access07 Feb 2026
Nature Communications

Volume: 17, P: 1-14
cellSTAAR: incorporating single-cell-sequencing-based functional data to boost power in rare variant association testing of noncoding regions

cellSTAAR advances noncoding rare variant association analysis by integrating single-cell genomics data.

Eric Van Buren
Yi Zhang
Xihong Lin
Research31 Dec 2025
Nature Methods

Volume: 23, P: 338-349
Radical prostatectomy without prior biopsy: an initial decision-making algorithm based on PSMA PET/mpMRI

Zhuoran Li
Jin Luo
Baojun Wang
Research31 Jan 2026
Prostate Cancer and Prostatic Diseases

P: 1-8
Programmable trans-splicing riboregulators for complex cellular logic computation

Scaling up genetic circuits is a longstanding challenge in synthetic biology. Here Gao et al. engineer split introns for programmable RNA-level gene regulation and integrate them with protein splicing for single-layer multi-input logic computation.

Yuanli Gao
Rizki Mardian
Baojun Wang
Research02 Jan 2025
Nature Chemical Biology

Volume: 21, P: 758-766
DR5/WDR12 balances p65 stability promoting sunitinib resistance in renal cell carcinoma

Wen Tao
Yuhao Dong
Xu Zhang
Research23 Mar 2026
Cell Death & Differentiation

P: 1-16
Precise solid-phase synthesis of CoFe@FeO_x nanoparticles for efficient polysulfide regulation in lithium/sodium-sulfur batteries

Solid-phase synthesis strategy is promising for fabricating desired complex metal nanoparticles on supports. Here, the authors synthesize CoFe@FeOx core-shell nanoparticles as the separator coatings via precise solid-phase method which effectively regulates polysulfides for lithium/ sodium-sulfur batteries.

Yanping Chen
Yu Yao
Jian Liu
ResearchOpen Access18 Nov 2023
Nature Communications

Volume: 14, P: 1-11
Integrated metabolomic and transcriptomic analyses identify MYB genes regulating key metabolites and agronomic traits in upland cotton Gossypium hirsutum

A multiomics dataset including genomics, transcriptomics and metabolomic variations across 403 upland cotton accessions identifies MYB genes regulating key metabolites and agronomic traits during cotton ovule and fiber development.

Xiaomeng Zhang
Xinquan Tian
Xiongming Du
Research03 Nov 2025
Nature Genetics

Volume: 57, P: 2819-2830
Plasmonic Ni-doped W₁₈O₄₉ with dual active sites drives efficient methanol dehydration to dimethyl ether

This study introduces Ni-doped W₁₈O₄₉ nanowires that integrate low-coordinated W and Ni dual active sites with surface plasmon resonance, facilitating solar-driven methanol dehydration for efficient dimethyl ether generation.

Dehua Tian
Yinlan Liang
Zaizhu Lou
ResearchOpen Access17 Nov 2025
Nature Communications

Volume: 16, P: 1-12
An expanded library of orthogonal split inteins enables modular multi-peptide assemblies

Inteins allow the joining of protein segments through scarless ligation. Here the authors assess 34 inteins to establish a library of 15 mutually orthogonal split inteins for in vivo applications, 10 of which are also active in vitro.

Filipe Pinto
Ella Lucille Thornton
Baojun Wang
ResearchOpen Access23 Mar 2020
Nature Communications

Volume: 11, P: 1-15
A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies

MultiSTAAR provides a general and flexible statistical framework for functionally informed multi-trait rare variant analysis of biobank-scale sequencing studies by jointly analyzing multiple traits and incorporating annotation information.

Xihao Li
Han Chen
Xihong Lin
Research07 Feb 2025
Nature Computational Science

Volume: 5, P: 125-143
Reprogrammed tracrRNAs enable repurposing of RNAs as crRNAs and sequence-specific RNA biosensors

In type II CRISPR systems, the guide RNA (gRNA) comprises a CRISPR RNA (crRNA) and a hybridized trans-acting CRISPR RNA (tracrRNA), both being essential in guided DNA targeting functions. Here the authors investigate the programmability of crRNA-tracrRNA hybridization for Cas9 and apply this to biosensing.

Yang Liu
Filipe Pinto
Baojun Wang
ResearchOpen Access11 Apr 2022
Nature Communications

Volume: 13, P: 1-12
Deficiency of Mouse CD4⁺CD25⁺Foxp3⁺ Regulatory T Cells in Xenogeneic Pig Thymus-Grafted Nude Mice Suffering from Autoimmune Diseases

Baojun Zhang
Chenming Sun
Yong Zhao
Research01 Oct 2008
Cellular & Molecular Immunology

Volume: 5, P: 325-332
Targeting STING elicits GSDMD-dependent pyroptosis and boosts anti-tumor immunity in renal cell carcinoma

Shengpan Wu
Baojun Wang
Xin Ma
Research04 Jan 2026
Oncogene

Volume: 45, P: 620-635
Constructing hierarchical submicrotubes from interconnected TiO₂ nanocrystals for high reversible capacity and long-life lithium-ion batteries

Ling Xin
Yong Liu
Chaolun Liang
ResearchOpen Access26 Mar 2014
Scientific Reports

Volume: 4, P: 1-7
Validation of human telomere length multi-ancestry meta-analysis association signals identifies POP5 and KBTBD6 as human telomere length regulation genes

Here the authors conduct a multi-ancestry meta-analysis of telomere length, used diverse approaches to identify genes underlying association signals, and experimentally validated POP5 and KBTBD6 as regulators of telomere length in human cells.

Rebecca Keener
Surya B. Chhetri
Alexis Battle
ResearchOpen Access24 May 2024
Nature Communications

Volume: 15, P: 1-21
A systematic approach to inserting split inteins for Boolean logic gate engineering and basal activity reduction

Split inteins are powerful tools for designing synthetic split proteins. Here the authors use a mini-Mu transposon screen to map split sites, enabling the development of protein-based logic gates and fine control of protein activity.

Trevor Y. H. Ho
Alexander Shao
Baojun Wang
ResearchOpen Access13 Apr 2021
Nature Communications

Volume: 12, P: 1-12
Flexible, stretchable, on-chip optical tweezers for high-throughput bioparticle manipulation

We developed flexible, stretchable, on-chip optical tweezers (FSOT) capable of high-throughput trapping and manipulation of bioparticles with sizes ranging from sub-100 nm to tens of micrometers on curved bio-substrates such as skin and intestines.

Ziyi He
Jianyun Xiong
Hongbao Xin
ResearchOpen Access03 Feb 2026
Light: Science & Applications

Volume: 15, P: 1-12
The genomic basis of geographic differentiation and fiber improvement in cultivated cotton

Genomic variations in 3,248 tetraploid cotton germplasms and multi-environmental genome-wide association analyses provide insights into the basis of geographic differentiation and fiber improvement in cultivated cotton.

Shoupu He
Gaofei Sun
Xiongming Du
Research15 Apr 2021
Nature Genetics

Volume: 53, P: 916-924
An organic electrochemical transistor for multi-modal sensing, memory and processing

An organic electrochemical transistor with a vertical traverse architecture and a crystalline–amorphous channel that can be selectively doped by ions can operate as a volatile receptor and a non-volatile synapse.

Shijie Wang
Xi Chen
Wei Ma
ResearchOpen Access27 Apr 2023
Nature Electronics

Volume: 6, P: 281-291
Dynamic monitoring of oscillatory enzyme activity of individual live bacteria via nanoplasmonic optical antennas

Nanoplasmonic antennas enable label-free monitoring of bacterial enzymes released via outer membrane vesicles. Real-time monitoring reveals the oscillatory behaviour of enzymatic release from individual bacteria as well as the effects of coupled oscillation from neighbouring bacteria.

Dengyun Lu
Guoshuai Zhu
Hongbao Xin
Research07 Aug 2023
Nature Photonics

Volume: 17, P: 904-911
Full-spectrum nonmetallic plasmonic carriers for efficient isopropanol dehydration

A nonmetallic plasmonic heterostructure of W₁₈O₄₉ nanowires on reduced-graphene oxide is reported for the efficient dehydration of isopropanol to 100% propylene. The energy barrier is found to be reduced under full-spectrum irradiation.

Changhai Lu
Daotong You
Zaizhu Lou
ResearchOpen Access15 Nov 2022
Nature Communications

Volume: 13, P: 1-8
Liquid biopsy-based single-cell metabolic phenotyping of lung cancer patients for informative diagnostics

Non-invasive methods to predict treatment response are urgently needed. Here in lung cancer, the authors develop a single-cell on-chip cytometry method to metabolically phenotype disseminated tumor cells, revealing metabolic heterogeneity and predictors of therapy response and survival.

Ziming Li
Zhuo Wang
Qihui Shi
ResearchOpen Access26 Aug 2019
Nature Communications

Volume: 10, P: 1-16
Formation and evolution of a pair of collisionless shocks in counter-streaming flows

Dawei Yuan
Yutong Li
Jie Zhang
ResearchOpen Access07 Mar 2017
Scientific Reports

Volume: 7, P: 1-8
Non-contact intracellular binding of chloroplasts in vivo

Yuchao Li
Hongbao Xin
Baojun Li
ResearchOpen Access04 Jun 2015
Scientific Reports

Volume: 5, P: 1-9
Quantum biological tunnel junction for electron transfer imaging in live cells

Although quantum biological electron transfer is important in many biological processes, imaging of the events in live cells has remained challenging. Here, the authors demonstrate real-time optical detection of quantum biological electron tunnelling between nanoparticles and cytochrome c inside living cells.

Hongbao Xin
Wen Jing Sim
Luke P. Lee
ResearchOpen Access19 Jul 2019
Nature Communications

Volume: 10, P: 1-11
Neoadjuvant toripalimab plus axitinib for clear cell renal cell carcinoma with inferior vena cava tumor thrombus: NEOTAX, a phase 2 study

Liangyou Gu
Cheng Peng
Xin Ma
ResearchOpen Access04 Oct 2024
Signal Transduction and Targeted Therapy

Volume: 9, P: 1-9
Regulating electron configuration of single Cu sites via unsaturated N,O-coordination for selective oxidation of benzene

Developing highly efficient catalysts for selective oxidation of benzene to phenol with low H₂O₂ consumption remains challenging. Here the authors report a highly active and selective non-noble metal catalyst for selective oxidation of benzene to phenol with low H2O2 addition via regulating the electron configuration of single-atom Cu catalyst.

Ting Zhang
Zhe Sun
Zhongkui Zhao
ResearchOpen Access16 Nov 2022
Nature Communications

Volume: 13, P: 1-8
Observation of full-parameter Jones matrix in bilayer metasurface

The realization of Jones matrix with full eight free parameters is particularly challenging. Here, the authors construct spatially varying Jones matrix with eight free parameters by cascading two-layer metasurfaces and use it for new optical functionalities.

Yanjun Bao
Fan Nan
Baojun Li
ResearchOpen Access07 Dec 2022
Nature Communications

Volume: 13, P: 1-8
The effect of air temperature on hospital admission of adults with community acquired pneumonia in Baotou, China

Wenfang Guo
Letai Yi
Minhui Li
ResearchOpen Access30 Apr 2021
Scientific Reports

Volume: 11, P: 1-7
Optofluidic realization and retaining of cell–cell contact using an abrupt tapered optical fibre

Hongbao Xin
Yao Zhang
Baojun Li
ResearchOpen Access17 Jun 2013
Scientific Reports

Volume: 3, P: 1-7
Urodynamic study findings and related influential factors in pediatric spastic cerebral palsy

Wenbin Jiang
Huizhen Sun
Bo Xiao
ResearchOpen Access28 Apr 2022
Scientific Reports

Volume: 12, P: 1-7
Preparation of ZnS@In₂S₃ Core@shell Composite for Enhanced Photocatalytic Degradation of Gaseous o-Dichlorobenzene under Visible Light

Baojun Liu
Xia Hu
Kwok-ho Lam
ResearchOpen Access27 Nov 2017
Scientific Reports

Volume: 7, P: 1-9
The therapeutic potential of Zuogui Wan in oligoasthenozoospermia: insights from network pharmacology, molecular docking, molecular dynamics simulation, and experimental validation

Mingzhao Zhang
Jisheng Wang
Xiao Li
ResearchOpen Access04 Nov 2025
Scientific Reports

Volume: 15, P: 1-22
Optical orientation and shifting of a single multiwalled carbon nanotube

Hongbao Xin
Baojun Li
ResearchOpen Access26 Sept 2014
Light: Science & Applications

Volume: 3, P: e205
Retraction Note: Targeting STING elicits GSDMD-dependent pyroptosis and boosts anti-tumor immunity in renal cell carcinoma

Shengpan Wu
Baojun Wang
Xin Ma
Amendments and Corrections08 Aug 2025
Oncogene

Volume: 44, P: 3154
Plasmon-assisted trapping of nanoparticles using a silver-nanowire-embedded PMMA nanofiber

Chang Cheng
Xiaohao Xu
Baojun Li
ResearchOpen Access04 Feb 2016
Scientific Reports

Volume: 6, P: 1-8
Controllable orientation of single silver nanowire using two fiber probes

Xiaohao Xu
Chang Cheng
Baojun Li
ResearchOpen Access05 Feb 2014
Scientific Reports

Volume: 4, P: 1-8
Wavelength-converted wave-guiding in dye-doped polymer nanofibers

Huaqing Yu
Baojun Li
ResearchOpen Access17 Apr 2013
Scientific Reports

Volume: 3, P: 1-6
Confined-space synthesis of single crystal TiO₂ nanowires in atmospheric vessel at low temperature: a generalized approach

Xiaoyue Wang
Hai Wang
Hui Shen
ResearchOpen Access30 Jan 2015
Scientific Reports

Volume: 5, P: 1-7
Optical regulation of cell chain

Xiaoshuai Liu
Jianbin Huang
Baojun Li
ResearchOpen Access22 Jun 2015
Scientific Reports

Volume: 5, P: 1-11
Non-contact fiber-optical trapping of motile bacteria: dynamics observation and energy estimation

Hongbao Xin
Qingyuan Liu
Baojun Li
ResearchOpen Access10 Oct 2014
Scientific Reports

Volume: 4, P: 1-8
Control of the differentiation of regulatory T cells and T_H17 cells by the DNA-binding inhibitor Id3

TGF-β and Foxp3 are required for the development of regulatory T cells. Chen and colleagues show that the helix-loop-helix proteins E2A and Id3 enhance Foxp3 expression and relieve it from inhibition by other transcription factors.

Takashi Maruyama
Jun Li
WanJun Chen
Research05 Dec 2010
Nature Immunology

Volume: 12, P: 86-95
Alternating modified CAPOX/CAPIRI plus bevacizumab in untreated unresectable metastatic colorectal cancer: a phase 2 trial

Sheng Li
Xiaoyou Li
Liangjun Zhu
ResearchOpen Access11 Dec 2024
Signal Transduction and Targeted Therapy

Volume: 9, P: 1-7
Lymph node dissection based on 18F-PSMA PET/CT during radical prostatectomy for intermediate and high risk prostate cancer: interim results of a prospective, randomized study

Zhuo Jia
Qiwei Liu
Baojun Wang
Research25 Sept 2025
Prostate Cancer and Prostatic Diseases

P: 1-7
New mouse models for exploring renal tumor extension into the inferior vena cava

In vivo, modeling of IVCTT reveals immune microenvironment dynamics and highlights the role of immune cells in regulating tumor thrombus progression in renal cancer.

Xiubin Li
Huaikang Li
Xin Ma
ResearchOpen Access05 Mar 2025
Communications Biology

Volume: 8, P: 1-11
RETRACTED ARTICLE: Targeting STING elicits GSDMD-dependent pyroptosis and boosts anti-tumor immunity in renal cell carcinoma

Shengpan Wu
Baojun Wang
Xin Ma
Research28 Mar 2024
Oncogene

Volume: 43, P: 1534-1548
Enhancer transcription profiling reveals an enhancer RNA-driven ferroptosis and new therapeutic opportunities in prostate cancer

Sheng Ma
Zixian Wang
Zhihua Wang
ResearchOpen Access14 Mar 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-21
Controlled synthesis of series Ni_xCo_3-xO₄ products: Morphological evolution towards quasi-single-crystal structure for high-performance and stable lithium-ion batteries

Yu Zhou
Yong Liu
Hui Shen
ResearchOpen Access24 Jun 2015
Scientific Reports

Volume: 5, P: 1-11

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