Nature Search

Single-step synthesis of delaminated MXenes in deep eutectic solvents

A single-step strategy is reported for the preparation of delaminated MXenes with positively charged surfaces from MAX phases. By combining Lewis acid etching with gas-mediated delamination in deep eutectic solvents, this approach offers a green, scalable and efficient route for MXene synthesis.

Fangbing Li
Yu Long
Quan-Hong Yang
Research11 Mar 2026
Nature Synthesis

P: 1-11
Structural insights into the coordinated regulation of the SLAH family in Arabidopsis thaliana

Plants utilize anion channels to adapt to environmental stresses. Here, authors elucidate the coordinated regulatory mechanisms within the SLAH family and demonstrate that tRNA molecules directly bind to and inhibit the SLAH1 anion channel.

Sensen Zhang
Xueying Huang
Zhiqiang Liu
ResearchOpen Access17 Dec 2025
Nature Communications

Volume: 17, P: 1-15
Multimodal learning with next-token prediction for large multimodal models

Emu3 enables large-scale text, image and video learning based solely on next-token prediction, matching the generation and perception performance of task-specific methods, with implications for the development of scalable and unified multimodal intelligence systems.

Xinlong Wang
Yufeng Cui
Tiejun Huang
ResearchOpen Access28 Jan 2026
Nature

Volume: 650, P: 327-333
Dark-based optical sectioning assists background removal in fluorescence microscopy

The Dark sectioning algorithm removes the background and provides single-frame optical sectioning in fluorescence microscopy. It offers improved quantitative analysis and deep-tissue segmentation accuracy and is compatible to diverse modalities.

Ruijie Cao
Yaning Li
Peng Xi
Research12 May 2025
Nature Methods

Volume: 22, P: 1299-1310
Precisely controlling endogenous protein dosage in hPSCs and derivatives to model FOXG1 syndrome

Altered dosage of developmental regulators such as transcription factors can result in disorders, such as FOXG1 syndrome. Here, the authors demonstrate the utility of SMASh technology for modulating protein dosage by modeling FOXG1 syndrome using human pluripotent stem cell-derived neurons and neural organoids.

Wenliang Zhu
Boya Zhang
Baoyang Hu
ResearchOpen Access25 Feb 2019
Nature Communications

Volume: 10, P: 1-18
Targeting retinoic acid receptor alpha-corepressor interaction activates chaperone-mediated autophagy and protects against retinal degeneration

Gomez-Sintes et al. have developed small molecules that selectively activate chaperone-mediated autophagy by stabilizing the interaction between retinoic acid receptor alpha and its co-repressor N-CoR1. They demonstrate the protective effect of boosting chaperone-mediated autophagy against retinal degeneration.

Raquel Gomez-Sintes
Qisheng Xin
Ana Maria Cuervo
ResearchOpen Access21 Jul 2022
Nature Communications

Volume: 13, P: 1-18
Generating viable mice with heritable embryonically lethal mutations using the CRISPR-Cas9 system in two-cell embryos

Roughly 25% of mouse genes are embryonically lethal when knocked out, preventing the generation of viable mouse models. Here the authors use CRISPR-Cas9 to edit one blastomere of a two-cell embryo to generate viable chimeric mice.

Yi Wu
Jing Zhang
Songlin Wang
ResearchOpen Access28 Jun 2019
Nature Communications

Volume: 10, P: 1-13
DSS1 restrains BRCA2’s engagement with dsDNA for homologous recombination, replication fork protection, and R-loop homeostasis

DSS1 is crucial for BRCA2 dependent genome repair. Here, the authors reveal how DSS1 restricts the dsDNA binding ability of BRCA2 to ensure BRCA2/RAD51 loading on ssDNA. Mutations in DSS1 disrupt this regulation, leading to impaired DNA repair, replication fork protection and R-loop suppression.

Yuxin Huang
Wenjing Li
Weixing Zhao
ResearchOpen Access17 Aug 2024
Nature Communications

Volume: 15, P: 1-17
Human pluripotent stem-cell-derived islets ameliorate diabetes in non-human primates

Improved glycemic control after transplantation of human pluripotent stem-cell-derived islets for diabetes treatment in non-human primates.

Yuanyuan Du
Zhen Liang
Hongkui Deng
Research03 Feb 2022
Nature Medicine

Volume: 28, P: 272-282
Designing light-element materials with large effective spin-orbit coupling

For materials composed of light elements the spin-orbit interaction is typically weak, due to their low atomic number. In this theoretical work, Li et al show how crystal symmetry and electron correlation can lead to an enhanced spin-orbit interaction and predict materials to realise this effect.

Jiayu Li
Qiushi Yao
Qihang Liu
ResearchOpen Access17 Feb 2022
Nature Communications

Volume: 13, P: 1-7
cGAS restricts PARP1-mediated microhomology-mediated end joining by suppressing poly-ADP-ribosylation

Haibo Yang
Boya Gao
Li Lan
Research17 Dec 2025
Cell Death & Differentiation

P: 1-12
Adipocyte Fatty Acid Binding Protein Potentiates Toxic Lipids-Induced Endoplasmic Reticulum Stress in Macrophages via Inhibition of Janus Kinase 2-dependent Autophagy

Ruby L. C. Hoo
Lingling Shu
Aimin Xu
ResearchOpen Access17 Jan 2017
Scientific Reports

Volume: 7, P: 1-15
Zika virus infection induces RNAi-mediated antiviral immunity in human neural progenitors and brain organoids

Yan-Peng Xu
Yang Qiu
Cheng-Feng Qin
Research27 Feb 2019
Cell Research

Volume: 29, P: 265-273
Type I collagen and fibromodulin enhance the tenogenic phenotype of hASCs and their potential for tendon regeneration

Tian Tu
Yuan Shi
Wei Liu
ResearchOpen Access14 Dec 2023
npj Regenerative Medicine

Volume: 8, P: 1-18
Differential antiviral immunity to Japanese encephalitis virus in developing cortical organoids

Boya Zhang
Yangzhige He
Guomin Zhou
ResearchOpen Access18 Jun 2018
Cell Death & Disease

Volume: 9, P: 1-10
Lidamycin induces mitophagy in pancreatic cancer cells by regulating the expression of Mfn2

Boya Wu
Bing Qi
Jing Chen
ResearchOpen Access05 Sept 2024
Scientific Reports

Volume: 14, P: 1-15
Molecular transport through capillaries made with atomic-scale precision

Nanometre-scale graphitic capillaries with atomically flat walls are engineered and studied, revealing unexpectedly fast transport of liquid water through channels that accommodate only a few layers of water.

B. Radha
A. Esfandiar
A. K. Geim
Research07 Sept 2016
Nature

Volume: 538, P: 222-225
The chemopreventive agent N-(4-hydroxyphenyl)retinamide induces apoptosis through a mitochondrial pathway regulated by proteins from the Bcl-2 family

Patricia Boya
Maria Celia Morales
Guido Kroemer
Research18 Sept 2003
Oncogene

Volume: 22, P: 6220-6230

Search

Single-step synthesis of delaminated MXenes in deep eutectic solvents

Structural insights into the coordinated regulation of the SLAH family in Arabidopsis thaliana

Multimodal learning with next-token prediction for large multimodal models

Dark-based optical sectioning assists background removal in fluorescence microscopy

Precisely controlling endogenous protein dosage in hPSCs and derivatives to model FOXG1 syndrome

Targeting retinoic acid receptor alpha-corepressor interaction activates chaperone-mediated autophagy and protects against retinal degeneration

Generating viable mice with heritable embryonically lethal mutations using the CRISPR-Cas9 system in two-cell embryos

DSS1 restrains BRCA2’s engagement with dsDNA for homologous recombination, replication fork protection, and R-loop homeostasis

Human pluripotent stem-cell-derived islets ameliorate diabetes in non-human primates

Designing light-element materials with large effective spin-orbit coupling

cGAS restricts PARP1-mediated microhomology-mediated end joining by suppressing poly-ADP-ribosylation

Adipocyte Fatty Acid Binding Protein Potentiates Toxic Lipids-Induced Endoplasmic Reticulum Stress in Macrophages via Inhibition of Janus Kinase 2-dependent Autophagy

Zika virus infection induces RNAi-mediated antiviral immunity in human neural progenitors and brain organoids

Type I collagen and fibromodulin enhance the tenogenic phenotype of hASCs and their potential for tendon regeneration

Differential antiviral immunity to Japanese encephalitis virus in developing cortical organoids

Lidamycin induces mitophagy in pancreatic cancer cells by regulating the expression of Mfn2

Molecular transport through capillaries made with atomic-scale precision

The chemopreventive agent N-(4-hydroxyphenyl)retinamide induces apoptosis through a mitochondrial pathway regulated by proteins from the Bcl-2 family

Search

Quick links

Search

Filter By:

Search

Quick links