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SARS-CoV-2 seroprevalence surveys provide estimates of the extent of prior infection in a population. In this nationally representative survey from Mexico, the authors estimate seroprevalence after the first epidemic wave at ~25%, with variation by region, age, socioeconomic status, and education level.

Nature Geoscience spoke with Jonatan Lassa, a scientist working on risk and disaster governance at Earth Sciences New Zealand; Carina Fearnley, an interdisciplinary scientist researching natural hazards and warning systems at University College London (UK); and Jeroen Warner, a social scientist studying disaster governance from Wageningen University (Netherlands), about how institutions, communities, and decision-making processes shape the effectiveness of natural hazard management and disaster mitigation.

Plasmodium vivax generally accounts for a low proportion of malaria cases in Africa, but population-level data on the distribution of infections is limited. Here, the authors use data from the Democratic Republic of the Congo and show that the prevalence is low (~3%) and diffusely spread.

Large igneous provinces may record pulses mantle plume upwellings and their relationship with deep-rooted mantle sources. Madrigal et al. present a new petrological model of the Pacific Ocean Large Igneous Province finding that mantle plume pulses were separated by 10–20 Ma.

Cristinziano et al. report the use of bacteriophages and dual beta lactam antibiotics to treat a patient with a Mycobacterium abscessus sternal wound infection. One of the phages was epigenetically modified for specificity to the M. abscessus strain.

Topsoil nitrogen stocks declined over a ten-year field warming experiment in a permafrost ecosystem due to enhanced plant nitrogen uptake, nitrogen leaching and gaseous losses, suggesting that permafrost soil nitrogen stocks are vulnerable to warming.

A comparison of alpha diversity (number of plant species) and dark diversity (species that are currently absent from a site despite being ecologically suitable) demonstrates the negative effects of regional-scale anthropogenic activity on plant diversity.

The advantage of living in cities compared with rural areas with respect to height and BMI in children and adolescents has generally become smaller globally from 1990 to 2020, except in sub-Saharan Africa.

As presented at the 2025 ASCO Annual Meeting: in a randomized controlled phase 3 trial evaluating subcutaneous administration of sasanlimab, an anti-PD-1 inhibitor, with Bacillus Calmette–Guérin induction and maintenance treatment, combination treatment significantly improved event-free survival versus standard-of-care therapy.

The authors show that polyglutamylation of spindle microtubules is essential for error-free chromosome segregation and is mediated through Tubulin Tyrosine Ligase Like 11 (TTLL11), which is found to be frequently downregulated in cancer.

A giant planet candidate roughly the size of Jupiter but more than 14 times as massive is observed by TESS and other instruments to be transiting the white dwarf star WD 1856+534.

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Tomaszowski et al show that co-mutations in Brca2 and Rad51c synergistically drive cancer and developmental disease, which was unexpected given their epistatic DNA repair roles, and expands our understanding of their tumor suppressive functions.

Spatially resolved transcriptomic profiling of primary tumours and metastases from patients with pancreatic cancer provides insight into the evolutionary progression to metastasis, and the variation in clonal architecture within and between individuals.

Nothofagus, tundra-like forests, either persisted in Antarctica through the Late Cenozoic Ice Age or relocated during intermitted warm intervals, as revealed by the macrofossil records of West Antarctica.

Genome-wide association studies (GWAS) have revealed gene variants associated with breast cancer, but their association with breast cancer development in Latinas is not clear. Here, the authors carry out a GWAS of breast cancer in Latinas and identify a significant protective variant of Indigenous American origin in the 6q25 region.

Analysis of HbA1c and FPG levels across 117 population-based studies demonstrates regional variation in prevalence of previously undiagnosed screen-detected diabetes using one or both measures and suggests that use of elevated FPG alone could underestimate diabetes prevalence in low- and middle-income countries.

From 1980 to 2018, the levels of total and non-high-density lipoprotein cholesterol increased in low- and middle-income countries, especially in east and southeast Asia, and decreased in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe.

The diversity and function of microbes inhabiting hydrothermal areas is a topic of active interest in marine microbiology. Here, the authors assemble genomes from Guaymas Basin hydrothermal sediments and describe the metabolic roles of the bacterial community, which includes five new bacterial candidate phyla

A catalogue of the vascular flora of New Guinea indicates that this island is the most floristically diverse in the world, and that 68% of the species identified are endemic to New Guinea.

A multi-ancestry genetic meta-analysis identifies 12 new loci associated with preeclampsia and gestational hypertension and proposes the integration of polygenic scores and clinical factors for disease prediction

Biogenic carbonate of eggshells can be used as a new geochronometer through direct calcite U-Pb dating, producing high accurate ages, as revealed by two tests on dinosaur eggs from North America and Mongolia.

Entamoeba histolytica causes human amebiasis. Although antibiotic therapy for this infection exists, there are limited treatment options for this potentially fatal invasive disease. Anjan Debnath and colleagues now report their identification of auranofin, an approved treatment for rheumatoid arthritis, as a candidate new drug for combating E. histolytica infection.

In this Consensus Statement, a consortium of microbiome scientists discuss current sequencing data sharing policies and propose the use of a Data Reuse Information (DRI) tag to promote equitable and collaborative data sharing.

A set of three papers in Nature reports a new proteomics resource from the UK Biobank and initial analysis of common and rare genetic variant associations with plasma protein levels.

Genome-wide association analysis of an improved telomere length score, calculated from quantitative PCR and whole-genome sequencing measurements in 462,666 individuals in the UK Biobank, identifies novel genes and variants underlying this trait.

High methionine and S-adenosylmethionine serum levels are related with obesity. Here the authors show that knockdown of methionine adenosyltransferase by using antisense oligonucleotides provides beneficial effects in obesity and comorbidities.

Rapid and localised changes in plate thinning caused by rifting is the primary control on the spatio-temporal distribution of volcanism in the Afar rift, according to argon dating of volcanic rocks from the Afar Stratoid series in Ethiopia.

Contrary to the view that urbanization is a major driver of the global rise in obesity, the global increase in body-mass index is shown to be mostly due to increases in the body-mass indexes of rural populations.

Tropical seagrasses in Patagonia during the Miocene imply a broader paleogeographic distribution than previously recognized, particularly in high South American latitudes indicating warmer sea surface temperatures, based on the seagrass botanical affinities.

Inhibition of histone and DNA methyltransferase activity enhances sensitivity to platinum-based and immunotherapy in a novel transgenic mouse model of metastatic bladder cancer.

Double-shell planetary nebula HuBi 1 has an inner shell that emits in low ionization potential species, and an outer shell that emits in high-ionization species. This is the inverse of the usual case. The cause is the nebula’s rapidly fading central star that went through a ‘born-again’ event.

Although vocal learning is widely speculated to depend on motor to auditory (i.e., forward) pathways, the neurons that convey forward signals important to vocal learning remain unknown. Here the authors identify neurons that transmit signals from songbird motor to auditory regions and demonstrate their role in vocal learning.