Nature Search

Increasing nationwide disparities in road freight emissions across cities

Globalized production and the rise of e-commerce have intensified urban freight activity, amplifying environmental impacts and raising equity concerns. This study examines freight-related emissions at the city level across the USA, uncovering two key factors driving disparities in emissions burdens.

Chengcheng Yu
Quan Yuan
Zhengtao Qin
Research14 Jan 2026
Nature Cities

Volume: 3, P: 28-37
Generative AI-based low-dose digital subtraction angiography for intra-operative radiation dose reduction: a randomized controlled trial

A model, trained to generate synthetic, patient-specific angiography images, reduced radiation exposure to patients and clinicians by two-thirds in a multicenter randomized controlled trial involving 1,068 patients.

Huangxuan Zhao
Yaowei Bai
Chuansheng Zheng
Research02 Jan 2026
Nature Medicine

Volume: 32, P: 288-296
Site-specific ligase-dependent conjugation with ring-opening linker improves safety and stability of HER2-targeting ADCs

Toxicity of antibody drug conjugates (ADCs) is often caused by off-target shedding of therapeutic payloads due to linker instability. Here, the authors demonstrate that site-specific ligase-dependent conjugation of therapeutic payloads to engineered trastuzumab via a ring-opening linker improves stability compared to conventional HER2- targeting ADCs.

Lei Huang
Gang Qin
Biyun Wang
ResearchOpen Access03 Nov 2025
Nature Communications

Volume: 16, P: 1-20
Inhibitory PD-1 axis maintains high-avidity stem-like CD8⁺ T cells

PD-1 blockade interferes with the selective expansion and maintenance of high-affinity TCR stem-like clones that have a critical role in effective checkpoint blockade therapy.

Jyh Liang Hor
Edward C. Schrom
Ronald N. Germain
ResearchOpen Access26 Nov 2025
Nature

Volume: 649, P: 194-204
From data to decarbonization: the digital economy’s role in reducing carbon emissions intensity and advancing environmental justice

Qingyang Wu
Xuemeng Liu
Pengwei He
ResearchOpen Access20 Jan 2026
npj Climate Action

Volume: 5, P: 1-20
Age-dependent patterns of the gut microbiome, antibiotic resistome, and pathogenicity in captive koalas (Phascolarctos cinereus)

Age-dependent dynamics of gut bacteriome, virome, and antibiotic resistome reveal microbial and pathogenic shifts shaping health in captive koalas.

Hualong Su
Peiyun Han
Jianguo He
ResearchOpen Access07 Dec 2025
Communications Biology

Volume: 9, P: 1-14
Macrophage STING signaling promotes fibrosis in benign airway stenosis via an IL6-STAT3 pathway

Benign airway stenosis (BAS) is characterised by acute and chronic inflammation of the trachea. Here the authors examine the function of cGAS-STING in BAS using mouse models and show involvement of macrophages and that inhibition of STING or macrophage depletion ameliorated BAS.

YiLin Chen
ChengCheng Yang
Chong Bai
ResearchOpen Access03 Jan 2025
Nature Communications

Volume: 16, P: 1-20
Author Correction: Kansl1 haploinsufficiency impairs autophagosome-lysosome fusion and links autophagic dysfunction with Koolen-de Vries syndrome in mice

Ting Li
Dingyi Lu
Xin Pan
Amendments and CorrectionsOpen Access17 Mar 2022
Nature Communications

Volume: 13, P: 1
Kansl1 haploinsufficiency impairs autophagosome-lysosome fusion and links autophagic dysfunction with Koolen-de Vries syndrome in mice

Here the authors show that the Koolen-de Vries syndrome associated gene KANSL1 modulates autophagosome-lysosome fusion via transcriptional regulation of autophagosomal gene Syntaxin17, and that 13-cis retinoic acid can reverses mitophagic defects and neurobehavioural abnormalities of mice lacking Kansl1.

Ting Li
Dingyi Lu
Xin Pan
ResearchOpen Access17 Feb 2022
Nature Communications

Volume: 13, P: 1-16
A preliminary study of ¹⁸F-FES PET/CT in predicting metastatic breast cancer in patients receiving docetaxel or fulvestrant with docetaxel

Chengcheng Gong
Zhongyi Yang
Yingjian Zhang
ResearchOpen Access26 Jul 2017
Scientific Reports

Volume: 7, P: 1-10
Gremlin1 is a therapeutically targetable FGFR1 ligand that regulates lineage plasticity and castration resistance in prostate cancer

Zhu and colleagues identify GREMLIN1 as an FGFR1 ligand that promotes plasticity and castration resistance in prostate cancer through regulation of MAPK signaling, and show that anti-GREMLIN1 antibody therapy synergizes with androgen deprivation.

Chaping Cheng
Jinming Wang
Helen He Zhu
Research27 May 2022
Nature Cancer

Volume: 3, P: 565-580
Comprehensive machine learning analysis of PANoptosis signatures in multiple myeloma identifies prognostic and immunotherapy biomarkers

Yashu Feng
Shuoting Wang
Jiajun Liu
ResearchOpen Access02 Jul 2025
Scientific Reports

Volume: 15, P: 1-17
Effects and mechanisms of phytohormones in enhancing the resistance of Oocystis borgei to high ammonium nitrogen stress

Xinyue Song
Yang Liu
Ning Zhang
ResearchOpen Access09 Jul 2025
Scientific Reports

Volume: 15, P: 1-12
Genome-wide association analysis identifies three new risk loci for gout arthritis in Han Chinese

Raised serum urate levels are a risk factor for gout, a common form of inflammatory arthritis. Here Li et al.conduct a multistage genome-wide association study in a Han Chinese population and identify three novel loci likely associated with the progression from hyperuricemia to gout.

Changgui Li
Zhiqiang Li
Yongyong Shi
ResearchOpen Access13 May 2015
Nature Communications

Volume: 6, P: 1-6
Insight-HXMT observations of jet-like corona in a black hole X-ray binary MAXI J1820+070

Evolution of accretion disk and corona during outbursts in black hole binary systems is still unclear. Here, the authors show spectral analysis of MAXI J1820+070 and propose a scenario of a dynamical corona to explain the evolution of the reflection fraction observed by Insight-HXMT.

Bei You
Yuoli Tuo
Yue Zhu
ResearchOpen Access15 Feb 2021
Nature Communications

Volume: 12, P: 1-11
The Effect of Chronic Bacterial Prostatitis on Semen Quality in Adult Men: A Meta-Analysis of Case-control Studies

Yonggang Shang
Chengcheng Liu
Shanhong Yi
ResearchOpen Access28 Nov 2014
Scientific Reports

Volume: 4, P: 1-6
Vasectomy and prostate cancer risk: a meta-analysis of cohort studies

Yonggang Shang
Guangwei Han
Shanhong Yi
ResearchOpen Access30 Apr 2015
Scientific Reports

Volume: 5, P: 1-5
Microbubble-mediated ultrasound promotes accumulation of bone marrow mesenchymal stem cell to the prostate for treating chronic bacterial prostatitis in rats

Shanhong Yi
Guangwei Han
Longkun Li
ResearchOpen Access22 Jan 2016
Scientific Reports

Volume: 6, P: 1-8
Improved circulating tumor DNA identification for detection of esophageal squamous cell carcinoma by enzymatic methyl sequencing and hybrid neural network

Jiangfeng Shen
Yuqi Ren
Dong Jiang
ResearchOpen Access26 Sept 2025
Scientific Reports

Volume: 15, P: 1-15
Randomized clinical trial of a digital medication system to enhance adherence in patients with severe mental disorders

Jia Zhou
Qian Zhai
Fang Yan
ResearchOpen Access05 Jun 2025
npj Digital Medicine

Volume: 8, P: 1-10
Upregulation of sestrins protect atriums against oxidative damage and fibrosis in human and experimental atrial fibrillation

Zengxiang Dong
Chaolan Lin
Wei Han
ResearchOpen Access11 Apr 2017
Scientific Reports

Volume: 7, P: 1-13
Integrating Internet multisource big data to predict the occurrence and development of COVID-19 cryptic transmission

Chengcheng Gao
Rui Zhang
Yazhou Wu
ResearchOpen Access28 Oct 2022
npj Digital Medicine

Volume: 5, P: 1-16
A multicenter study on two-stage transfer learning model for duct-dependent CHDs screening in fetal echocardiography

Jiajie Tang
Yongen Liang
Hongying Wang
ResearchOpen Access12 Aug 2023
npj Digital Medicine

Volume: 6, P: 1-10
Multi-layer regional railway network and equitable economic development of megaregions

Chengcheng Yu
Wentao Dong
Quan Yuan
ResearchOpen Access19 Jan 2025
npj Sustainable Mobility and Transport

Volume: 2, P: 1-12
Bacteria-induced expression of the pig-derived protegrin-1 transgene specifically in the respiratory tract of mice enhances resistance to airway bacterial infection

Fang Zeng
Chengcheng Zhao
Zhenfang Wu
ResearchOpen Access29 Sept 2020
Scientific Reports

Volume: 10, P: 1-11
Correction to: ERCC6L that is up-regulated in high grade of renal cell carcinoma enhances cell viability in vitro and promotes tumor growth in vivo potentially through modulating MAPK signalling pathway

Gejun Zhang
Zi Yu
Yu Zeng
Amendments and Corrections28 Jan 2022
Cancer Gene Therapy

Volume: 29, P: 1296
PROTAC induced-BET protein degradation exhibits potent anti-osteosarcoma activity by triggering apoptosis

Chengcheng Shi
Huapeng Zhang
Yi Zhang
ResearchOpen Access25 Oct 2019
Cell Death & Disease

Volume: 10, P: 1-11
Single-cell transcriptome analysis of epithelial, immune, and stromal signatures and interactions in human ovarian cancer

A single-cell interaction study on ovarian cancer reveals heterogeneous epithelial-immune-stromal cellular compartments and their interactions in shaping the tumor microenvironment, especially through the NECTIN2-TIGIT interaction.

Chaochao Chai
Langchao Liang
Yonglun Luo
ResearchOpen Access26 Jan 2024
Communications Biology

Volume: 7, P: 1-15
IL-21 Stimulates the expression and activation of cell cycle regulators and promotes cell proliferation in EBV-positive diffuse large B cell lymphoma

Yuxuan Wang
Chengcheng Wang
Liang Wu
ResearchOpen Access23 Jul 2020
Scientific Reports

Volume: 10, P: 1-13
ERCC6L that is up-regulated in high grade of renal cell carcinoma enhances cell viability in vitro and promotes tumor growth in vivo potentially through modulating MAPK signalling pathway

Gejun Zhang
Zi Yu
Yu Zeng
Research21 Nov 2018
Cancer Gene Therapy

Volume: 26, P: 323-333
Whole-genome sequencing provides insights into the genetic diversity and domestication of bitter gourd (Momordica spp.)

Junjie Cui
Yan Yang
Kailin Hu
ResearchOpen Access01 Jun 2020
Horticulture Research

Volume: 7, P: 1-11
Protein activation mapping of human sun-protected epidermis after an acute dose of erythemic solar simulated light

Janine G. Einspahr
Clara Curiel-Lewandrowski
Emanuel F. Petricoin III
ResearchOpen Access21 Sept 2017
npj Precision Oncology

Volume: 1, P: 1-10
Cellular graphene aerogel combines ultralow weight and high mechanical strength: A highly efficient reactor for catalytic hydrogenation

Bingxing Zhang
Jianling Zhang
Ning Zhao
ResearchOpen Access12 May 2016
Scientific Reports

Volume: 6, P: 1-10
Production of functional human nerve growth factor from the saliva of transgenic mice by using salivary glands as bioreactors

Fang Zeng
Zicong Li
Zhenfang Wu
ResearchOpen Access24 Jan 2017
Scientific Reports

Volume: 7, P: 1-13
Joint utilization of genetic analysis and semi-cloning technology reveals a digenic etiology of Müllerian anomalies

Lingbo Wang
Ying Zhang
Keqin Hua
Correspondence18 Oct 2019
Cell Research

Volume: 30, P: 91-94

Search

Increasing nationwide disparities in road freight emissions across cities

Generative AI-based low-dose digital subtraction angiography for intra-operative radiation dose reduction: a randomized controlled trial

Site-specific ligase-dependent conjugation with ring-opening linker improves safety and stability of HER2-targeting ADCs

Inhibitory PD-1 axis maintains high-avidity stem-like CD8⁺ T cells

From data to decarbonization: the digital economy’s role in reducing carbon emissions intensity and advancing environmental justice

Age-dependent patterns of the gut microbiome, antibiotic resistome, and pathogenicity in captive koalas (Phascolarctos cinereus)

Macrophage STING signaling promotes fibrosis in benign airway stenosis via an IL6-STAT3 pathway

Author Correction: Kansl1 haploinsufficiency impairs autophagosome-lysosome fusion and links autophagic dysfunction with Koolen-de Vries syndrome in mice

Kansl1 haploinsufficiency impairs autophagosome-lysosome fusion and links autophagic dysfunction with Koolen-de Vries syndrome in mice

A preliminary study of ¹⁸F-FES PET/CT in predicting metastatic breast cancer in patients receiving docetaxel or fulvestrant with docetaxel

Gremlin1 is a therapeutically targetable FGFR1 ligand that regulates lineage plasticity and castration resistance in prostate cancer

Comprehensive machine learning analysis of PANoptosis signatures in multiple myeloma identifies prognostic and immunotherapy biomarkers

Effects and mechanisms of phytohormones in enhancing the resistance of Oocystis borgei to high ammonium nitrogen stress

Genome-wide association analysis identifies three new risk loci for gout arthritis in Han Chinese

Insight-HXMT observations of jet-like corona in a black hole X-ray binary MAXI J1820+070

The Effect of Chronic Bacterial Prostatitis on Semen Quality in Adult Men: A Meta-Analysis of Case-control Studies

Vasectomy and prostate cancer risk: a meta-analysis of cohort studies

Microbubble-mediated ultrasound promotes accumulation of bone marrow mesenchymal stem cell to the prostate for treating chronic bacterial prostatitis in rats

Improved circulating tumor DNA identification for detection of esophageal squamous cell carcinoma by enzymatic methyl sequencing and hybrid neural network

Randomized clinical trial of a digital medication system to enhance adherence in patients with severe mental disorders

Upregulation of sestrins protect atriums against oxidative damage and fibrosis in human and experimental atrial fibrillation

Integrating Internet multisource big data to predict the occurrence and development of COVID-19 cryptic transmission

A multicenter study on two-stage transfer learning model for duct-dependent CHDs screening in fetal echocardiography

Multi-layer regional railway network and equitable economic development of megaregions

Bacteria-induced expression of the pig-derived protegrin-1 transgene specifically in the respiratory tract of mice enhances resistance to airway bacterial infection

Correction to: ERCC6L that is up-regulated in high grade of renal cell carcinoma enhances cell viability in vitro and promotes tumor growth in vivo potentially through modulating MAPK signalling pathway

PROTAC induced-BET protein degradation exhibits potent anti-osteosarcoma activity by triggering apoptosis

Single-cell transcriptome analysis of epithelial, immune, and stromal signatures and interactions in human ovarian cancer

IL-21 Stimulates the expression and activation of cell cycle regulators and promotes cell proliferation in EBV-positive diffuse large B cell lymphoma

ERCC6L that is up-regulated in high grade of renal cell carcinoma enhances cell viability in vitro and promotes tumor growth in vivo potentially through modulating MAPK signalling pathway

Whole-genome sequencing provides insights into the genetic diversity and domestication of bitter gourd (Momordica spp.)

Protein activation mapping of human sun-protected epidermis after an acute dose of erythemic solar simulated light

Cellular graphene aerogel combines ultralow weight and high mechanical strength: A highly efficient reactor for catalytic hydrogenation

Production of functional human nerve growth factor from the saliva of transgenic mice by using salivary glands as bioreactors

Joint utilization of genetic analysis and semi-cloning technology reveals a digenic etiology of Müllerian anomalies

Search

Quick links

Search

Filter By:

Search

Quick links