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Comparative analysis of single-cell data from the amphioxus hepatic caecum and the liver of several vertebrates shows how genome duplication contributes to cellular diversification and functional complexity of the vertebrate liver.

The authors report three palaeomagnetic poles from the North China craton and document a large round-trip true polar wander oscillation during 155−141 Ma that may have affected biotic evolution in East Asia and global extinction and endemism.

Samples from the Chang’e-6 mission show that the lunar magnetic field rebounded in field strength after its previous sharp decline of about 3.1 Ga.

The selective degradation of mitochondria by autophagy is essential for cell homeostasis. Here, Nan et al show that the effector protein BipD, secreted by Burkholderia pseudomallei, is able to modulate host mitophagy to promote its survival.

In Hirschsprung’s disease, Schwann cell-derived extracellular vesicles transfer MIR22HG to enteric neural crest cells (ENCCs), downregulating MPP3 in an m6Adependent manner and leading to impaired ENCC colonization.

Two potent mitophagy inducers, identified and characterized via unsupervised machine learning and a cross-species screening approach, ameliorated the pathology of Alzheimer’s disease in worms and mice.

Covalent organic frameworks (COFs) are promising photocatalysts for the direct photosynthesis of H₂O₂, but their symmetric structure can lead to weak O₂ adsorption. Now thiophene sulfur atoms are introduced into COFs to induce local asymmetric electron distributions, which enhance the O₂ adsorption capacity and interaction of the COFs, promoting direct photosynthesis of H₂O₂.

Here the authors provide new radiocarbon, U-series, and OSL dates for Homo sapiens fossils from Tongtianyan cave, southern China, placing them at 33-23 thousand years ago and indicating widespread presence of Homo sapiens across eastern Asia in the Late Pleistocene.

A damage-free transfer printing method utilizing localized molten gallium enables the precise manipulation of fragile micro- and nano-films. The method offers adhesion regulation and reliability that cannot be easily achieved by fully liquefied stamps.

An array of chemically engineered CRISPR RNAs and AsCpf1 messenger RNAs leads to improvements in gene-cutting efficiency up to about 300% with respect to unmodified CRISPR RNA and plasmid-encoding AsCpf1.

The current development of orange-red or deep-red multi-resonance emitters is bound with a double-boron-conjugated structure. Here, the authors report single-boron sulfur-embedded emitters with intramolecular locks, achieving maximum device efficiency close to 40% for organic light emitting diodes.

Insect-like biomimetic compound eyes have many technological applications. Here, the authors present a facile fabrication scheme involving microfluidics assisted 3D printing that permits to completely separate design, optimization and construction of optical and sensor components.

Differential spectrometers recognise different wavelength via their differential photodetector responsivity. The authors combine an 8-pixel hemispherical perovskite photodetector with neural network algorithms to realise 3D trajectory tracking and 2D location tacking with colour classification.

Unidirectional spin Hall magnetoresistance refers to an asymmetric resistance response, which allows for the readout of the magnetic state from two terminal devices. Here, Zhang et al demonstrate a large unidirectional spin hall magnetoresistance FeNi/Pt/Bi₂Se₃ trilayers and present a robust random-access magnetoresistance device.

Intermediate soil acidification alters the denitrifier community composition and induces high nitrous oxide (N₂O) emissions, which contributes to the observed acceleration of N₂O emissions from global soils

Analysing the genome of a snailfish from the Mariana Trench, the authors show genetic changes associated with unique morphological and physiological adaptations to life in the hadal zone.

This study introduces a ChickenGTEx atlas of regulatory variants across 28 tissues and illustrates its utility in deciphering association signals for 39 complex traits in chickens.

Here the authors develop an iterative particle sieving method called CryoSieve, demonstrating this method outperforms other cryo-EM particle sorting algorithms to reveal that most particles are unnecessary in final stacks.

Fe₃C microflakes with high magnetic anisotropy are prepared through solid-state phase transformation and electrochemical dealloying. The magnetic anisotropy can be tuned by adjusting the morphology, resulting in optimized ferromagnetic resonance behavior for microwave absorption

Mesozoic deformation of the North China Craton occurred via lithospheric thickening followed by thinning and extension triggered by flat-slab subduction and rollback, according to four-dimensional mantle flow models of the plate–mantle system.

The design and optimization of a metasurface is a computationally- and time-consuming effort. Here, the authors propose a neural network-based algorithm for functional metasurface design, and demonstrate it for some functional metasurfaces.

2D metallenes have spurred considerable interests in heterogeneous catalytic reactions. Here the authors report an efficient galvanic replacement strategy to construct Pd metallenes mediated by Nb2C MXenes for boosting alkynes semihydrogenation.

The use of acyl functional groups as nucleophilic synthons in transition metal-catalysed carbometallation of unsaturated hydrocarbons remains challenging. Here, nickel-catalysed acylzincation reactions of alkynes and alkenes with organozinc reagents under 1 atm of CO are developed, featuring high functional group tolerance, a broad substrate scope and mild conditions.

Plants deploy numerous receptor-like kinases (RLKs) to respond to pathogens. Here the authors show that NIK1, an RLK that positively regulates antiviral immunity, negatively regulates the response to bacteria by modulating FLS2/BAK1 complex formation, suggesting crosstalk between bacterial and viral immunity.

Wear-resistant metals have long been a pursuit of reducing wear-related energy and material loss. Here the authors present the ‘reactive wear protection’ strategy via friction-induced in situ formation of strong and deformable oxide nanocomposites on a surface.

Smoking-associated DNA methylation changes in whole blood have been reported by many EWAS. Here, the authors use a cell-type deconvolution algorithm to identify cell-type specific DNA methylation signals in seven EWAS, identifying lineage-specific smoking-associated DNA methylation changes.

Topological flat bands offer a solid-state platform for studying the interplay between topology and electron correlations. Here, the authors demonstrate that a prototypical 3D Dirac material can host topological flat bands under magnetic fields due to polar-distortion-assisted Rashba splitting.