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A universal design strategy for nanograined metals aimed at utilizing oxygen nanoclustering to achieve the highly desired combination of high strength and large deformability that evades inverse Hall-Petch softening.

Monolayer graphene can support the quantum Hall effect up to room temperature. Here, the authors provide evidence that graphene encapsulated in hexagonal boron nitride realizes a novel transport regime where dissipation in the quantum Hall phase is mediated predominantly by electron-phonon scattering rather than disorder scattering.

Whilst superlattices containing thin films of 5d transition metal oxides are expected to yield strong interfacial coupling, only weak effects have been observed. Here, the authors report strong coupling between 3d SrMnO₃ and 5d SrIrO₃due to the interplay of strong Coulomb and spin orbit interactions.

In most metals the optical Hall effect is very small at visible wavelengths, and usually can only be observed at low frequencies. Here, Am-Shalom et al present a technique involving a large amplitude modulation of the external magnetic field, allowing for the measurement of the optical Hall effect in a range of metals at visible wavelengths.

The boundaries of fractional quantum Hall states can host multiple, interacting one-dimensional edge modes, which test our understanding of strongly interacting systems. Here the authors observe the edge-mode equilibration transition that was predicted for the ν=2/3 fractional quantum Hall state.

Helical modes are induced in a high-mobility two-dimensional electron gas without strong spin–orbit coupling. This platform provides a versatile playground for investigating compounded quantum Hall edge states.

Two challenging questions related to the quantum Hall effect (QHE) are how edge reconstruction works and where the current flows. A new model now gives the answer for two types of QHE states — two separate downstream chiral edge channels are involved.

Nonlinear Hall effect is a potential tool for exploring correlated phase transitions in topological semimetals. Here, the authors demonstrate an enhanced nonlinear Hall effect arising from a one-dimensional charge density wave in TaIrTe₄.

Orbital angular momentum transfer from optical vortex beams to electronic quantum Hall states is reported in a graphene sheet, showing a robust contribution to the radial photocurrent that depends on the vorticity of light.

Large-effect variants in autism remain elusive. Here, the authors use long-read sequencing to assemble phased genomes for 189 individuals, identifying pathogenic variants in TBL1XR1, MECP2, and SYNGAP1, plus nine candidate structural variants missed by short-read methods.

In Bi₂O₂Se thin films, the local inversion-symmetry breaking in two sectors of the [Bi₂O₂]²⁺ layer yields opposite Rashba spin polarizations, which compensate each other and give rise to the hidden Rashba effect. Hence, the films exhibit only even-integer quantum Hall states, but there is no sign of odd-integer states.

Careful measurements of the zero-field quantum anomalous Hall effect find a less-precisely-quantized Hall conductivity than the integer quantum Hall effect. Here, the authors theoretically study the effects of nonlinear corrections to the Hall conductivity in both topological and trivial magnetic insulators.

Mechanisms for generating spin-polarized currents may be helpful for applications. Now one such mechanism that uses the unusual Landau-level spectrum of WSe₂ under a strong magnetic field is demonstrated.

The broken-symmetry edge states that are the hallmark of the quantum Hall effect in graphene have eluded spatial measurements. Here, the authors spatially map the quantum Hall broken-symmetry edge states using atomic force microscopy and show a gapped ground state proceeding from the bulk through to the quantum Hall edge boundary.

Understanding charge transport and the fundamental limits on conductivity in polymer semiconductors is important for improving device performance. Wanget al. report a transport regime close to band-like conduction and the observation of the Hall effect in an electrochemically-doped polymer semiconductor.

cellSTAAR advances noncoding rare variant association analysis by integrating single-cell genomics data.

Instabilities in chiral plasmas can amplify electromagnetic waves, raising the question of whether chiral solids behave similarly. Now a magneto-chiral instability is demonstrated in tellurium, observed as growing terahertz emission after photoexcitation.

Compressibility measurements on high-quality monolayer WSe₂ samples enable the observation of fractional quantum Hall states in the lowest Landau levels.

Climate change can alter when and how animals grow, breed, and migrate, but it is unclear whether this allows populations to persist. This global study shows that shifts in seasonal timing are key to helping vertebrate species maintain population growth under global warming.

Atomically thin layers of a correlated topological semimetal exhibit a nonlinear Hall effect that can be used to fabricate terahertz photodetectors with a room-temperature responsivity of 0.3 A W⁻¹, a broadband terahertz range and a picosecond response time.

Electron hopping in geometrically frustrated lattices can result in a rich variety of unusual behaviours. Now, the orbital arrangement in a van der Waals metal with a non-frustrated, primitive lattice is found to show similar effects.

We show that an insulating bulk state and helical edge state coexist in Bi₄Br₄ and that this coexistence persists up to room temperature.

3D higher-order topological insulators (HOTIs) exhibit 1D hinge states depending on extrinsic sample details, while intrinsic features of HOTIs remain unknown. Here, K.S. Lin et al. introduce the framework of spin-resolved topology to show that helical HOTIs can realize a doubled axion insulator phase with nontrivial partial axion angles.

Plasmacytoid dendritic cells produce type I interferons in response to viral sensing. Here the authors show that amines inhibit these plasmacytoid dendritic cell responses through CXCR4 engagement.

Here the authors provide an explanation for 95% of examined predicted loss of function variants found in disease-associated haploinsufficient genes in the Genome Aggregation Database (gnomAD), underscoring the power of the presented analysis to minimize false assignments of disease risk.

Electronic devices usually rely on the charge or spin of electrons to encode information. A less exploited route is to manipulate the valley quantum number of electrons. It is now shown that the generation, macroscopic transport and detection of valley-polarized electrons in bulk diamond can be achieved with a relaxation time of 300 ns at 77 K, forming a basis for valleytronic devices.

A spin–orbit torque efficiency of around 2.7 can be achieved in heterostructures based on the bismuthate BaPb_1−xBi_xO₃, which can be used to drive magnetization switching at current densities of 4 × 10⁵ A cm⁻².

Royer and colleagues find a principal dimension of neural dynamic similarity dissociating unimodal and association cortices. Systematic variations in local and macroscale constraints across the cortex also followed this pattern.

Cell-cell fusion is fundamental to physiological processes such as muscle formation and viral infection. Here, the authors show that the proteins embedded on the plasma membrane present a biophysical barrier that can regulate cell-cell fusion.

The authors demonstrate voltage-controlled multiferroic magnon torque in BiFeO₃ heterostructures, enabling reconfigurable logic-in-memory devices. This work highlights potential for low-power, scalable magnonics in room-temperature computing.

During SARS-CoV-2 infection caspase-8 fuels harmful inflammation independent of apoptosis. Genetic loss of caspase-8 reduces cytokine levels, lowers viral load and mitigates disease severity, revealing non-apoptotic caspase-8 as a key driver of severe COVID-19.

InSb nanowire crosses, which could be used for braiding Majorana modes, are synthesized using a technique that allows two growing nanowires to merge.

Using well-calibrated statistical methods the authors jointly analyze Undiagnosed Diseases Network genomes, identifying known and novel disease genes. Software is publicly available to support future cross-cohort rare disease discovery efforts.

Here the authors show that tissue-resident memory and exhausted T cells in tumors are distinct populations that are shaped by relative presence or absence of TCR signals, suggesting that a tailored therapeutic strategy is needed to target each subset.

There has been a lot of interest in using antiferromagnets for magnetic memories, due to their fast dynamics, and resilience to stray fields. Such a memory was supposed to be switched by a spin-orbit torque. Here, Zhu and Ralph find that as a ferrimagnet approaches the magnetic compensation point, the spin-orbit torque acting on the ferrimagnet vanishes due to competing spin relaxation processes.

The impact of late Pleistocene climate change on ecosystems has been hard to assess. Here, the authors sequence ancient DNA from Hall’s Cave, Texas and find that both plant and vertebrate diversity decreased with cooling, and though plant diversity recovered with rewarming, megafauna went extinct.

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Chronic care manages long-term, progressive conditions, while acute care handles short-term ones. Here, authors show chronic conditions account for most of the global health burden, with 68% of DALYs and 93% of YLDs attributed to chronic care needs.

By virtue of strong spin-orbit coupling, a current-carrying heavy metal may generate a torque on the magnetization of an interfaced ferromagnetic metal. Here, the authors demonstrate how this effect assists the magnetic reversal of ferromagnetic insulators with perpendicular magnetic anisotropy.

Hiʻiaka is the largest moon of the distant dwarf planet Haumea. Here, the authors report the first multi-chord stellar occultations of Hiʻiaka, revealing its size, shape, and density, suggesting an origin from Haumea’s icy mantle.