Nature Search

Neuromodulation of lumbosacral spinal networks enables independent stepping after complete paraplegia

In a human subject with chronic paraplegia, a combination of epidural electrical stimulation and long-term rehabilitative training have culminated in the first report of unassisted, voluntary independent stepping in a paralyzed individual.

Megan L. Gill
Peter J. Grahn
Kristin D. Zhao
Research24 Sept 2018
Nature Medicine

Volume: 24, P: 1677-1682
Education of healthcare professionals to improve guideline adherence in atrial fibrillation: the STEEER-AF cluster-randomized clinical trial

In a cluster-randomized trial conducted across 70 medical centers in six countries, a 16-week structured educational program for healthcare providers improved adherence to guidelines for rhythm control but not for stroke prevention in individuals with atrial fibrillation.

Dipak Kotecha
Karina V. Bunting
Paulus Kirchhof
ResearchOpen Access13 Jun 2025
Nature Medicine

Volume: 31, P: 2647-2654
General anaesthesia decreases the uniqueness of brain functional connectivity across individuals and species

Each individual is unique and so is their brain activity. Using brain fingerprinting from functional MRI during anaesthesia, Luppi et al. find that human brains become temporarily more difficult to identify and tell apart when unconscious.

Andrea I. Luppi
Daniel Golkowski
Bratislav Misic
ResearchOpen Access24 Mar 2025
Nature Human Behaviour

Volume: 9, P: 987-1004
The evolutionary path of the epithelial sodium channel δ-subunit in Cetartiodactyla points to a role in sodium sensing

Zahnow et al. investigate the evolution of epithelial sodium channels (ENaCs) in mammals returning to marine life. ENaCs are built of αβγ- or δβγ-subunits. Their study suggests the SCNN1D gene encoding the δ-subunit suffers pseudogenization events in marine mammals due to high-salinity environment.

Fynn Zahnow
Chiara Jäger
Mike Althaus
ResearchOpen Access04 Jul 2025
Communications Biology

Volume: 8, P: 1-15
Rapid transitions of the ocean's deep circulation induced by changes in surface water fluxes

Thomas F. Stocker
Daniel G. Wright
Research27 Jun 1991
Nature

Volume: 351, P: 729-732
Survey of spiking in the mouse visual system reveals functional hierarchy

A large, open dataset containing parallel recordings from six visual cortical and two thalamic areas of the mouse brain is presented, from which the relative timing of activity in response to visual stimuli and behaviour is used to construct a hierarchy scheme that corresponds to anatomical connectivity data.

Joshua H. Siegle
Xiaoxuan Jia
Christof Koch
Research20 Jan 2021
Nature

Volume: 592, P: 86-92
Effects of the agility boot camp with cognitive challenge (ABC-C) exercise program for Parkinson’s disease

Se Hee Jung
Naoya Hasegawa
Fay B. Horak
ResearchOpen Access02 Nov 2020
npj Parkinson's Disease

Volume: 6, P: 1-8
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

Fine-mapping of causal variants and integration of epigenetic and chromatin conformation data identify likely target genes for 150 breast cancer risk regions.

Laura Fachal
Hugues Aschard
Alison M. Dunning
Research07 Jan 2020
Nature Genetics

Volume: 52, P: 56-73
The electroencephalography protocol for the Accelerating Medicines Partnership® Schizophrenia Program: Reliability and stability of measures

Daniel H. Mathalon
Spero Nicholas
Gregory A. Light
ResearchOpen Access06 Jun 2025
Schizophrenia

Volume: 11, P: 1-18
28-country global study on associations between cultural characteristics and Recovery College fidelity

Yasuhiro Kotera
Amy Ronaldson
Mike Slade
ResearchOpen Access08 Oct 2024
npj Mental Health Research

Volume: 3, P: 1-15
Challenges of microscopy technology dissemination to resource-constrained communities

Discussions at a recent conference on microscopy technology dissemination spotlighted the importance of setting technology adoption capable of producing scientific outcome as the end goal. This Comment examines current global efforts in microscopy dissemination and summarizes the challenges and paths forward.

Jesse S. Aaron
Caron A. Jacobs
Teng-Leong Chew
Comments & Opinion06 May 2025
Nature Methods

P: 1-5
A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers

Breast cancer risk for BRCA1/BRCA2 mutation carriers varies depending on other genetic factors. Here, the authors perform a case-only genome-wide association study and highlight novel loci associated with breast cancer risk for BRCA1/BRCA2 mutation carriers.

Juliette Coignard
Michael Lush
Antonis C. Antoniou
ResearchOpen Access17 Feb 2021
Nature Communications

Volume: 12, P: 1-22
M1 transcranial direct current stimulation augments laparoscopic surgical skill acquisition

Daniel Galvin
Adam J. Toth
Mark J. Campbell
ResearchOpen Access23 Aug 2023
Scientific Reports

Volume: 13, P: 1-9
An international Delphi consensus for reporting of setting in psychedelic clinical trials

A large international panel of experts reach consensus on a new standard for reporting settings in psychedelic trials, identifying 30 key non-pharmacological factors to strengthen the rigor of psychedelic research.

Chloé Pronovost-Morgan
Kyle T. Greenway
Keith Williams
ResearchOpen Access03 Jun 2025
Nature Medicine

Volume: 31, P: 2186-2195
Characterization of just one atom using synchrotron X-rays

Using a specialized tip as a detector, the fingerprints of a single atom of iron and terbium are observed in synchrotron X-ray absorption spectra, allowing elemental and chemical characterization one atom at a time.

Tolulope M. Ajayi
Nozomi Shirato
Saw-Wai Hla
Research31 May 2023
Nature

Volume: 618, P: 69-73
Cost-effectiveness of a wetting method intervention to reduce cassava cyanide-related cognitive impairment in children

A wetting method for cassava flour can further reduce cyanide exposure and its disease burden among children. The cost-effectiveness of the method in reducing cognitive disability is assessed in the Democratic Republic of the Congo.

Chen Chen
Espérance Kashala-Abotnes
Felicia Wu
Research21 Jul 2021
Nature Food

Volume: 2, P: 469-472
Single-cell integration reveals metaplasia in inflammatory gut diseases

The study provides a comprehensive transcriptomic atlas of the human gastrointestinal tract across the lifespan, highlighting inflammation-induced changes in epithelial stem cells that alter mucosal architecture and promote further inflammation.

Amanda J. Oliver
Ni Huang
Sarah A. Teichmann
ResearchOpen Access20 Nov 2024
Nature

Volume: 635, P: 699-707
Cognitive assessment in the Accelerating Medicines Partnership® Schizophrenia Program: harmonization priorities and strategies in a diverse international sample

Kelly Allott
Walid Yassin
William S. Stone
ResearchOpen Access24 Mar 2025
Schizophrenia

Volume: 11, P: 1-12
Novelty and imitation within the brain: a Darwinian neurodynamic approach to combinatorial problems

Dániel Czégel
Hamza Giaffar
Eörs Szathmáry
ResearchOpen Access15 Jun 2021
Scientific Reports

Volume: 11, P: 1-14
Whole-brain modelling identifies distinct but convergent paths to unconsciousness in anaesthesia and disorders of consciousness

Perturbations in a large-scale whole-brain model suggest that anesthesia and injury may be imparting functionally similar effects in terms of brain dynamics.

Andrea I. Luppi
Pedro A. M. Mediano
Emmanuel A. Stamatakis
ResearchOpen Access20 Apr 2022
Communications Biology

Volume: 5, P: 1-15
Estimation of ventilatory thresholds during exercise using respiratory wearable sensors

Felipe Contreras-Briceño
Jorge Cancino
Daniel E. Hurtado
ResearchOpen Access26 Jul 2024
npj Digital Medicine

Volume: 7, P: 1-12
Inter-Layer Coupling Induced Valence Band Edge Shift in Mono- to Few-Layer MoS₂

Daniel J. Trainer
Aleksei V. Putilov
Maria Iavarone
ResearchOpen Access13 Jan 2017
Scientific Reports

Volume: 7, P: 1-11
Strategic vision for improving human health at The Forefront of Genomics

In this Perspective, authors from the National Human Genome Research Institute (NHGRI) present a vision for human genomics research for the coming decade.

Eric D. Green
Chris Gunter
Teri A. Manolio
Reviews28 Oct 2020
Nature

Volume: 586, P: 683-692
More than apples and oranges - Detecting cancer with a fruit fly's antenna

Martin Strauch
Alja Lüdke
Corrado Di Natale
ResearchOpen Access06 Jan 2014
Scientific Reports

Volume: 4, P: 1-9
Author Correction: A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers

Juliette Coignard
Michael Lush
Antonis C. Antoniou
Amendments and CorrectionsOpen Access14 May 2021
Nature Communications

Volume: 12, P: 1-2
Exercise-induced myokines and their effect on prostate cancer

Exercise improves outcomes in prostate cancer, but the mechanisms behind this are poorly understood. This Review discusses exercise-induced blood alterations, with a focus on muscle-secreted myokines, which could have both direct and indirect effects on tumour proliferation.

Jin-Soo Kim
Daniel A. Galvão
Dennis R. Taaffe
Reviews22 Jun 2021
Nature Reviews Urology

Volume: 18, P: 519-542
An autosomal dominant neurological disorder caused by de novo variants in FAR1 resulting in uncontrolled synthesis of ether lipids

Sacha Ferdinandusse
Kirsty McWalter
Frédéric M. Vaz
ResearchOpen Access26 Nov 2020
Genetics in Medicine

Volume: 23, P: 740-750
In Utero Gene Therapy (IUGT) Using GLOBE Lentiviral Vector Phenotypically Corrects the Heterozygous Humanised Mouse Model and Its Progress Can Be Monitored Using MRI Techniques

Panicos Shangaris
Stavros P. Loukogeorgakis
Anna L. David
ResearchOpen Access12 Aug 2019
Scientific Reports

Volume: 9, P: 1-17
Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants

Daniel R. Barnes
Matti A. Rookus
Antonis C. Antoniou
ResearchOpen Access15 Jul 2020
Genetics in Medicine

Volume: 22, P: 1653-1666
A framework for understanding how activities associated with dog ownership relate to human well-being

Ana Maria Barcelos
Niko Kargas
Daniel S. Mills
ResearchOpen Access09 Jul 2020
Scientific Reports

Volume: 10, P: 1-12
Vibration mechanosignals superimposed to resistive exercise result in baseline skeletal muscle transcriptome profiles following chronic disuse in bed rest

Michele Salanova
Guido Gambara
Dieter Blottner
ResearchOpen Access24 Nov 2015
Scientific Reports

Volume: 5, P: 1-15
The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer

Gisella Figlioli
Massimo Bogliolo
Paolo Peterlongo
ResearchOpen Access01 Nov 2019
npj Breast Cancer

Volume: 5, P: 1-14
Copy number variants as modifiers of breast cancer risk for BRCA1/BRCA2 pathogenic variant carriers

The risk of germline copy number variants (CNVs) in BRCA1 and BRCA2 pathogenic variant carriers in breast cancer is assessed, with CNVs overlapping SULT1A1 decreasing breast cancer risk in BRCA1 carriers.

Christopher Hakkaart
John F. Pearson
Logan C. Walker
ResearchOpen Access06 Oct 2022
Communications Biology

Volume: 5, P: 1-15
Visualization of defect induced in-gap states in monolayer MoS₂

Daniel J. Trainer
Jouko Nieminen
Maria Iavarone
ResearchOpen Access28 Feb 2022
npj 2D Materials and Applications

Volume: 6, P: 1-7
An alternative approach to establishing unbiased colorectal cancer risk estimation in Lynch syndrome

Manon Suerink
Mar Rodríguez-Girondo
Maartje Nielsen
Research17 Jun 2019
Genetics in Medicine

Volume: 21, P: 2706-2712
Erratum: Inter-Layer Coupling Induced Valence Band Edge Shift in Mono- to Few-Layer MoS₂

Daniel J. Trainer
Aleksei V. Putilov
Maria Iavarone
Amendments and CorrectionsOpen Access14 Mar 2017
Scientific Reports

Volume: 7, P: 1
Effects of Prior Fluoxetine Treatment on EEG Sleep in Women with Recurrent Depression

Daniel J Buysse
David J Kupfer
Ellen Frank
Research01 Aug 1999
Neuropsychopharmacology

Volume: 21, P: 258-267

Search

Neuromodulation of lumbosacral spinal networks enables independent stepping after complete paraplegia

Education of healthcare professionals to improve guideline adherence in atrial fibrillation: the STEEER-AF cluster-randomized clinical trial

General anaesthesia decreases the uniqueness of brain functional connectivity across individuals and species

The evolutionary path of the epithelial sodium channel δ-subunit in Cetartiodactyla points to a role in sodium sensing

Rapid transitions of the ocean's deep circulation induced by changes in surface water fluxes

Survey of spiking in the mouse visual system reveals functional hierarchy

Effects of the agility boot camp with cognitive challenge (ABC-C) exercise program for Parkinson’s disease

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

The electroencephalography protocol for the Accelerating Medicines Partnership® Schizophrenia Program: Reliability and stability of measures

28-country global study on associations between cultural characteristics and Recovery College fidelity

Challenges of microscopy technology dissemination to resource-constrained communities

A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers

M1 transcranial direct current stimulation augments laparoscopic surgical skill acquisition

An international Delphi consensus for reporting of setting in psychedelic clinical trials

Characterization of just one atom using synchrotron X-rays

Cost-effectiveness of a wetting method intervention to reduce cassava cyanide-related cognitive impairment in children

Single-cell integration reveals metaplasia in inflammatory gut diseases

Cognitive assessment in the Accelerating Medicines Partnership® Schizophrenia Program: harmonization priorities and strategies in a diverse international sample

Novelty and imitation within the brain: a Darwinian neurodynamic approach to combinatorial problems

Whole-brain modelling identifies distinct but convergent paths to unconsciousness in anaesthesia and disorders of consciousness

Estimation of ventilatory thresholds during exercise using respiratory wearable sensors

Inter-Layer Coupling Induced Valence Band Edge Shift in Mono- to Few-Layer MoS₂

Strategic vision for improving human health at The Forefront of Genomics

More than apples and oranges - Detecting cancer with a fruit fly's antenna

Author Correction: A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers

Exercise-induced myokines and their effect on prostate cancer

An autosomal dominant neurological disorder caused by de novo variants in FAR1 resulting in uncontrolled synthesis of ether lipids

In Utero Gene Therapy (IUGT) Using GLOBE Lentiviral Vector Phenotypically Corrects the Heterozygous Humanised Mouse Model and Its Progress Can Be Monitored Using MRI Techniques

Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants

A framework for understanding how activities associated with dog ownership relate to human well-being

Vibration mechanosignals superimposed to resistive exercise result in baseline skeletal muscle transcriptome profiles following chronic disuse in bed rest

The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer

Copy number variants as modifiers of breast cancer risk for BRCA1/BRCA2 pathogenic variant carriers

Visualization of defect induced in-gap states in monolayer MoS₂

An alternative approach to establishing unbiased colorectal cancer risk estimation in Lynch syndrome

Erratum: Inter-Layer Coupling Induced Valence Band Edge Shift in Mono- to Few-Layer MoS₂

Effects of Prior Fluoxetine Treatment on EEG Sleep in Women with Recurrent Depression

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