When the brain detects ongoing fuel depletion, sympathetic nervous system outflow to white adipose tissue induces lipolysis to mobilize fuel. Yet there exists a subset of ‘stable adipocytes’ that resist lipolysis via this mechanism. The discovery of a novel lipolysis mechanism reshapes our understanding of how body energy requirements are met in times of need.
- Alison H. Affinati
- Michael W. Schwartz
