Nature Search

Ligand-engineered CsPbBr₃ perovskite quantum dots for self-healing and stable performance

Perovskite quantum dots offer easy synthesis and high performance but suffer from poor heat and moisture stability due to organic components. Here, the authors demonstrate a ligand-engineering strategy to improve the environmental stability of all-inorganic CsPbBr₃ perovskite quantum dots using trioctylphosphine, lead stearate, and chlorobenzene.

Yuan Zhang
Yong Pan
Dongwen Gao
ResearchOpen Access08 May 2026
Communications Materials

P: 1-14
Establishing a multicellular model by three-dimensional cell-assembly technique for metabolic syndrome

Mingen Xu
Yongnian Yan
Xiaohong Wang
ResearchOpen Access08 Jan 2008
Nature Precedings

P: 1
Broad pH-resistant microdroplet SERS platform based on Ag@SiO₂@PVP NPs for real-time analysis of microbial metabolites

Haixia Zhao
Jizhuo Liu
Li Chen
ResearchOpen Access25 May 2026
Microsystems & Nanoengineering

Volume: 12, P: 1-14
Revealing electron transport connectivity as an important factor influencing stability of organic solar cells

The commercialization of organic solar cells has been hindered by the limited device stability. Here, authors show that the connectivity of electron transport network is a key factor determining electron transport and device stability, with polymeric acceptors likely to establish such a network.

Haixia Hu
Rui Zhang
Hang Yin
ResearchOpen Access16 Jul 2025
Nature Communications

Volume: 16, P: 1-14
Breeding ideotype maize with enhanced yield through genomics-guided pyramiding of favorable alleles

Genomics-guided design of ideotype maize through pyramiding favorable alleles led to hybrid maize varieties suitable for high-density planting, with enhanced yield.

Wen Yao
Lixia Ku
Yanhui Chen
Research17 Mar 2026
Nature Genetics

Volume: 58, P: 916-927
A functionally tunable magnetic nanochains platform for N-glycoproteomic analysis of extracellular vesicles from ultratrace biofluids

A tunable magnetic nanochains platform (EVGpro) enables tandem enrichment, proteomic, and N-glycoproteomic analysis of extracellular vesicles from ultratrace biofluids. EVGpro identifies N-glycoprotein signatures and two asthenozoospermia subtypes.

Mingyang Li
Xiaorong Song
Xuejiang Guo
ResearchOpen Access16 Aug 2025
Nature Communications

Volume: 16, P: 1-18
Mutation of SlARC6 leads to tissue-specific defects in chloroplast development in tomato

Jiang Chang
Fanyu Zhang
Shuang Wu
ResearchOpen Access01 Jun 2021
Horticulture Research

Volume: 8, P: 1-11
Structure-based design of potent and selective inhibitors targeting RIPK3 for eliminating on-target toxicity in vitro

Here the authors described the structure-based design of novel, selective RIPK3 inhibitors that do not induce on-target apoptosis by occupying a unique hydrophobic site and locking RIPK3 into an inactive conformation.

Haixia Su
Guofeng Chen
Yechun Xu
ResearchOpen Access08 May 2025
Nature Communications

Volume: 16, P: 1-15
The association of insulin resistance and obesity with uterine fibroids in non-diabetic populations: a cross-sectional study

Danting Sun
Haixia Liu
Teng Lv
ResearchOpen Access25 Nov 2025
Scientific Reports

Volume: 15, P: 1-9
Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease

SARS-CoV-2 3CL protease (3CL^pro) is essential for coronavirus replication and of great interest as an antiviral drug target. Here, the authors show that the naturally occurring flavonoid myricetin is a non-peptidomimetic and covalent inhibitor of 3CL^pro, and they solve crystal structures of 3CL^pro with myricetin and derivatives, which reveal that the pyrogallol group covalently modifies the catalytic cysteine.

Haixia Su
Sheng Yao
Yechun Xu
ResearchOpen Access15 Jun 2021
Nature Communications

Volume: 12, P: 1-12
Grapevine pangenome facilitates trait genetics and genomic breeding

By constructing a graph-based grapevine pangenome reference (Grapepan v.1.0) and incorporating structural variations and phenotypic maps, the study investigates the genetic basis of agronomic traits, empowering grapevine genomic breeding.

Zhongjie Liu
Nan Wang
Yongfeng Zhou
ResearchOpen Access04 Nov 2024
Nature Genetics

Volume: 56, P: 2804-2814
Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir

In this study, the authors report the structure-based discovery and preclinical evaluation of 2 simnotrelvir, an orally bioavailable 3CLpro inhibitor that blocks replication of SARS-CoV-2 variants in 3 vitro, shows robust efficacy in a mouse model and good safety and pharmacokinetic profiles in rats 4 and monkeys.

Xiangrui Jiang
Haixia Su
Yechun Xu
ResearchOpen Access13 Oct 2023
Nature Communications

Volume: 14, P: 1-15
Long-term efficacy of therapeutic drug monitoring-guided optimization of ustekinumab maintenance therapy for Crohn’s disease patients

Haixia Ren
Juan Su
Ping An
ResearchOpen Access15 Jul 2025
Scientific Reports

Volume: 15, P: 1-10
RMzyme: regulations of RNA-modifying enzymes in humans

Ruihan Luo
Haixia Xu
Hong Wu
ResearchOpen Access12 Feb 2026
Signal Transduction and Targeted Therapy

Volume: 11, P: 1-17
SGSM2 inhibits thyroid cancer progression by activating RAP1 and enhancing competitive RAS inhibition

A schematic model of SGSM2 suppressing the progression of RAS^WT thyroid cancer.

Xi Su
Dong Chen
Wei Wei
ResearchOpen Access09 Mar 2022
Cell Death & Disease

Volume: 13, P: 1-9
METTL3 preferentially enhances non-m⁶A translation of epigenetic factors and promotes tumourigenesis

Wei et al. identify that cytoplasmic METTL3 interacts with PABPC1 to facilitate translation of epigenetic factor mRNAs without m⁶A modification to promote tumour progression, suggesting an m⁶A-independent mechanism for this methyltransferase.

Xueju Wei
Yue Huo
Jia Yu
Research04 Aug 2022
Nature Cell Biology

Volume: 24, P: 1278-1290
Bovine lactoferrin drives cell cycle arrest and alters the transcriptomic profile of NSCLC cells

Jinxian Su
Yu Zhao
Haixia Zhang
ResearchOpen Access30 Jul 2025
Scientific Reports

Volume: 15, P: 1-11
Rupatadine-inhibited OTUD3 promotes DLBCL progression and immune evasion through deubiquitinating MYL12A and PD-L1

Ying Sui
Ziyang Shen
Haixia Cao
ResearchOpen Access03 Aug 2024
Cell Death & Disease

Volume: 15, P: 1-16
De novo design of protein condensation inhibitors by targeting an allosteric site of cGAS

In this work, authors design novel protein condensation inhibitors (PCIs) targeting an allosteric site of cGAS, blocking DNA interactions and phase separation to suppress immune activation, and demonstrate therapeutic potential in inflammatory disease models.

Wenfeng Zhao
Guofeng Chen
Yechun Xu
ResearchOpen Access03 Jun 2025
Nature Communications

Volume: 16, P: 1-20
CYP2S1 is a synthetic lethal target in BRAF^V600E-driven thyroid cancers

Yiqi Li
Xi Su
Peng Hou
ResearchOpen Access11 Sept 2020
Signal Transduction and Targeted Therapy

Volume: 5, P: 1-12
Spatiotemporal and global profiling of DNA–protein interactions enables discovery of low-affinity transcription factors

Precise analysis of DNA–protein interactions can help to better understand various biological processes. Now, the ‘light-induced lysine (K) enabled crosslinking’ strategy (shortened to ‘LIKE-XL’) has been developed for spatiotemporal and global profiling of DNA–protein interactions, affording the discovery of low-affinity interactions between transcription factors and DNA using sequence-specific DNA baits.

An-Di Guo
Ke-Nian Yan
Xiao-Hua Chen
Research27 Apr 2023
Nature Chemistry

Volume: 15, P: 803-814
Encoding of tactile information in hand via skin-integrated wireless haptic interface

The haptic interface is an essential part of human–machine interfaces where tactile information is delivered between human and machine. Yao et al. develop a soft, ultrathin, miniaturized and wireless electrotactile system that allows virtual tactile information to be reproduced over the hand.

Kuanming Yao
Jingkun Zhou
Xinge Yu
Research17 Oct 2022
Nature Machine Intelligence

Volume: 4, P: 893-903
Proteostatic reactivation of the developmental transcription factor TBX3 drives BRAF/MAPK-mediated tumorigenesis

MAPK-driven tumorigenesis is often related to epithelial dedifferentiation but the regulatory mechanism is less clear. Here, the authors show that MAPK activation upregulates USP15 to promote deubiquitylation and stability of TBX3, a transcription factor implicated in thyroid development and differentiation, driving tumorigenesis in a BRAFV600E thyroid tumor model.

Zhenlei Zhang
Yufan Wu
Li Zhao
ResearchOpen Access15 May 2024
Nature Communications

Volume: 15, P: 1-18
SunUp and Sunset genomes revealed impact of particle bombardment mediated transformation and domestication history in papaya

Genome assemblies for the SunUp transgenic papaya and its progenitor Sunset identify three transgene-insertions in SunUp. Resequencing of 86 papaya genomes highlights the impacts of breeding and geographic origin.

Jingjing Yue
Robert VanBuren
Ray Ming
Research12 May 2022
Nature Genetics

Volume: 54, P: 715-724
TMK-based cell-surface auxin signalling activates cell-wall acidification

Auxin induces transmembrane-kinase-dependent activation of H⁺-ATPase in the plasma membrane through phosphorylation of its penultimate threonine residue, promoting apoplastic acidification and hypocotyl cell elongation in Arabidopsis.

Wenwei Lin
Xiang Zhou
Zhenbiao Yang
ResearchOpen Access27 Oct 2021
Nature

Volume: 599, P: 278-282
Author Correction: Proteostatic reactivation of the developmental transcription factor TBX3 drives BRAF/MAPK-mediated tumorigenesis

Zhenlei Zhang
Yufan Wu
Li Zhao
Amendments and CorrectionsOpen Access10 Jun 2024
Nature Communications

Volume: 15, P: 1
Overcoming bubble formation in polydimethylsiloxane-made PCR chips: mechanism and elimination with a high-pressure liquid seal

Shiyuan Gao
Tiegang Xu
Xinxin Li
ResearchOpen Access27 Sept 2024
Microsystems & Nanoengineering

Volume: 10, P: 1-11
Importance of embryo aneuploidy screening in preimplantation genetic diagnosis for monogenic diseases using the karyomap gene chip

Gang Li
Wenbin Niu
Yingpu Sun
ResearchOpen Access16 Feb 2018
Scientific Reports

Volume: 8, P: 1-6
Controlled fabrication of nanoscale wrinkle structure by fluorocarbon plasma for highly transparent triboelectric nanogenerator

Xiaoliang Cheng
Liming Miao
Haixia Zhang
ResearchOpen Access30 Jan 2017
Microsystems & Nanoengineering

Volume: 3, P: 1-9
The Serum Profile of Hypercytokinemia Factors Identified in H7N9-Infected Patients can Predict Fatal Outcomes

Jing Guo
Fengming Huang
Chengyu Jiang
ResearchOpen Access01 Jun 2015
Scientific Reports

Volume: 5, P: 1-10
Nuclear-localized pyruvate kinases control phosphorylation of histone H3 on threonine 11

This study reports that the nucleocytoplasmic shuttling of pyruvate kinase 6 (PK6), PK7 and PK8 mediates phosphorylation of H3 at threonine 11, represses flowering time, and promotes hypocotyl and pedicel elongation in Arabidopsis.

Pengcheng Hu
Yanmei Xu
Yong Ding
Research04 Oct 2024
Nature Plants

Volume: 10, P: 1682-1697
Maternal acute SARS-CoV-2 infection impairs preimplantation embryo development and reprograms the early offspring hematopoietic system

Meiling Zhang
Di Liu
Yuxuan Zheng
ResearchOpen Access23 Dec 2025
Cell Discovery

Volume: 11, P: 1-19
Chromosome-level genome assembly of the pine wood nematode carrier Arhopalus unicolor

Xiangying Zou
Liqiong Zeng
Jun Su
ResearchOpen Access20 Jan 2025
Scientific Data

Volume: 12, P: 1-8
A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23

Jing Wang, Fengchun Zhang and colleagues report the results of a genome-wide association study of primary Sjögren's syndrome, a common autoimmune disease. They confirm associations in the STAT4, TNFAIP3 and HLA regions and identify a new susceptibility locus in the GTF2I region at 7q11.23.

Yongzhe Li
Kunlin Zhang
Fengchun Zhang
Research06 Oct 2013
Nature Genetics

Volume: 45, P: 1361-1365
Discovery of novel non-peptidic and non-covalent small-molecule 3CL^pro inhibitors as potential candidate for COVID-19 treatment

Zhidong Jiang
Bo Feng
Yu Zhou
ResearchOpen Access22 May 2023
Signal Transduction and Targeted Therapy

Volume: 8, P: 1-4
Correction: Discovery of novel non-peptidic and non-covalent small-molecule 3CL^pro inhibitors as potential candidate for COVID-19 treatment

Zhidong Jiang
Bo Feng
Yu Zhou
Amendments and CorrectionsOpen Access13 Oct 2023
Signal Transduction and Targeted Therapy

Volume: 8, P: 1-2
A highly efficient degradation mechanism of methyl orange using Fe-based metallic glass powders

Shenghui Xie
Ping Huang
Haixia Qian
ResearchOpen Access23 Feb 2016
Scientific Reports

Volume: 6, P: 1-10
Isolation and characterization of centromeric repetitive DNA sequences in Saccharum spontaneum

Wenpan Zhang
Sheng Zuo
Kai Wang
ResearchOpen Access30 Jan 2017
Scientific Reports

Volume: 7, P: 1-12
Overt gastrointestinal bleeding following haploidentical haematopoietic stem cell transplantation: incidence, outcomes and predictive models

Xueyan Sun
Yan Su
Xiaohui Zhang
Research07 Jan 2021
Bone Marrow Transplantation

Volume: 56, P: 1341-1351
Correction: Corrigendum: The Serum Profile of Hypercytokinemia Factors Identified in H7N9-Infected Patients can Predict Fatal Outcomes

Jing Guo
Fengming Huang
Chengyu Jiang
Amendments and CorrectionsOpen Access23 Feb 2016
Scientific Reports

Volume: 6, P: 1
Drought resistance mechanisms of Phedimus aizoon L.

Yuhang Liu
Zhongqun He
Shengju Long
ResearchOpen Access30 Jun 2021
Scientific Reports

Volume: 11, P: 1-14
At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Munib Mesinovic
Xin Ci Wong
David Zucman
ResearchOpen Access16 Jul 2024
Scientific Reports

Volume: 14, P: 1-43
Metabolomics integrated with machine learning to discriminate the geographic origin of Rougui Wuyi rock tea

Yifei Peng
Chao Zheng
Xiaomin Yu
ResearchOpen Access16 Mar 2023
npj Science of Food

Volume: 7, P: 1-10
High-throughput single-cell transcriptomics reveals the female germline differentiation trajectory in Arabidopsis thaliana

Zhimin Hou, Yanhui Liu et al. used single cell RNA-seq to analyze the model organism, Arabidopsis thaliana, at three stages during female germline differentiation. They reconstructed the continuous trajectory of female germline differentiation, providing a valuable reference for future investigation of germline cell fate determination in A. thaliana.

Zhimin Hou
Yanhui Liu
Yuan Qin
ResearchOpen Access01 Oct 2021
Communications Biology

Volume: 4, P: 1-16
The Dendrobium catenatum Lindl. genome sequence provides insights into polysaccharide synthase, floral development and adaptive evolution

Guo-Qiang Zhang
Qing Xu
Zhong-Jian Liu
ResearchOpen Access12 Jan 2016
Scientific Reports

Volume: 6, P: 1-10
O-glycosylation pattern of the SARS-CoV-2 spike protein reveals an “O-Follow-N” rule

Wenmin Tian
Delin Li
George Fu Gao
CorrespondenceOpen Access02 Aug 2021
Cell Research

Volume: 31, P: 1123-1125
ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

Ali Abbas
Sheryl Ann Abdukahil
Luis Felipe Reyes
ResearchOpen Access30 Jul 2022
Scientific Data

Volume: 9, P: 1-22

Search

Filter By:

Search

Quick links