AIRES (algorithmic iterative reticular synthesis) is an integrated cycle combining automated synthesis, image recognition, single-crystal X-ray diffraction and algorithmic decision-making to maximize the discovery of distinct crystal structures. Demonstrated on zeolitic imidazolate frameworks, AIRES offers a systematic and efficient blueprint for reticular synthesis, with broad implications for accelerating materials discovery.
- Zichao Rong
- Zihao Chen
- Omar M. Yaghi
