Nature Search

Meso–macroporous hydrogel for direct litre-scale isolation of extracellular vesicles

A hydrogel matrix fabricated by cryo-photocrosslinking enables the direct, scalable isolation of extracellular vesicles from diverse biofluids without preprocessing, allowing for in-gel preservation for long-term storage and biomedical applications.

Junbeom Kim
Minjin Kang
Nakwon Choi
ResearchOpen Access24 Sept 2025
Nature Nanotechnology

Volume: 20, P: 1678-1687
Responsive nematic gels from the self-assembly of aqueous nanofibres

Hydrogels have a variety of applications including tissue engineering and controlled drug delivery. Here, liquid-crystal hydrogels are developed which transform into a fluid solution upon cooling; cells can be encapsulated in the gel at room temperature, then released at physiological temperatures.

Zhegang Huang
Hyojin Lee
Myongsoo Lee
Research06 Sept 2011
Nature Communications

Volume: 2, P: 1-5
Hybrid tungsten oxyselenide/graphene electrodes for near-lossless 2D semiconductor phase modulators

Shi Guo
Sung-Gyu Lee
Sang Hoon Chae
ResearchOpen Access03 Jan 2026
Light: Science & Applications

Volume: 15, P: 1-10
A biodegradable and self-deployable electronic tent electrode for brain cortex interfacing

A biodegradable electronic tent electrode array that can be inserted into the brain cortex using a syringe, where it then expands to 200 times its original size, can be used for electrocorticography monitoring.

Jae-Young Bae
Gyeong-Seok Hwang
Seung-Kyun Kang
Research05 Aug 2024
Nature Electronics

Volume: 7, P: 815-828
Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice

Autism is ~4 times more common in males. Jung et al. reveal male-preponderant abnormal behaviors in mice lacking CHD8, a chromatin remodeler, accompanying sexually dimorphic changes in neuronal firing, synaptic transmission, and gene expression.

Hwajin Jung
Haram Park
Eunjoon Kim
Research13 Aug 2018
Nature Neuroscience

Volume: 21, P: 1218-1228
Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice

Seizures can occur in autism spectrum disorders (ASD). Here, the authors report that mice lacking the ASD related Ank2 gene show abnormal behaviours, and juvenile seizure related death, through impaired Kv7 potassium channel function.

Hyoseon Oh
Suho Lee
Eunjoon Kim
ResearchOpen Access15 Jun 2023
Nature Communications

Volume: 14, P: 1-20
Structural basis for assembly and disassembly of the IGF/IGFBP/ALS ternary complex

Insulin-like growth factor 1 (IGF1) regulates growth and differentiation. Here, authors report the atomic structure of the ternary complex (IGF1/IGF-binding protein3/acid labile subunit) and its assembly/disassembly mechanism for IGF bioavailability.

Hyojin Kim
Yaoyao Fu
Ho Min Kim
ResearchOpen Access30 Jul 2022
Nature Communications

Volume: 13, P: 1-17
Early postnatal serotonin modulation prevents adult-stage deficits in Arid1b-deficient mice through synaptic transcriptional reprogramming

ARID1B is a chromatin remodeler associated with autism spectrum disorders. Here the authors demonstrate that early postnatal serotonin modulation prevents adult stage deficits in Arid1b-deficient mice through synaptic transcriptional reprogramming.

Hyosang Kim
Doyoun Kim
Eunjoon Kim
ResearchOpen Access27 Aug 2022
Nature Communications

Volume: 13, P: 1-19
Adaptive self-healing electronic epineurium for chronic bidirectional neural interfaces

Electronic implantable devices should be soft and stretchable, such that nerves can adapt mechanically and autonomously. Here, the authors present an adaptive self-healing electronic epineurium which can form compressive stress-free and strain-insensitive electronics-nerve interfaces.

Kang-Il Song
Hyunseon Seo
Donghee Son
ResearchOpen Access21 Aug 2020
Nature Communications

Volume: 11, P: 1-10
TRRUST: a reference database of human transcriptional regulatory interactions

Heonjong Han
Hongseok Shim
Insuk Lee
ResearchOpen Access12 Jun 2015
Scientific Reports

Volume: 5, P: 1-11
Synthesis of Ordered Mesoporous Phenanthrenequinone-Carbon via π-π Interaction-Dependent Vapor Pressure for Rechargeable Batteries

Mi-Sook Kwon
Aram Choi
Kyu Tae Lee
ResearchOpen Access10 Dec 2014
Scientific Reports

Volume: 4, P: 1-7
An amphibious artificial vision system with a panoramic visual field

In an approach inspired by the functional and anatomical structure of fiddler crab eyes, an amphibious and panoramic artificial vision system can be created by integrating a microlens arrays with a flexible comb-shaped silicon photodiode array on a spherical structure.

Mincheol Lee
Gil Ju Lee
Young Min Song
Research11 Jul 2022
Nature Electronics

Volume: 5, P: 452-459
SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties

Mouse and human studies reveal that incorrect gene dosage of SHANK3 (a gene linked to some human neuropsychiatric disorders, including autism spectrum disorder) is associated with behavioural abnormalities including mania, possibly because of actin regulation problems in excitatory/inhibitory synapses.

Kihoon Han
J. Lloyd Holder Jr
Huda Y. Zoghbi
Research23 Oct 2013
Nature

Volume: 503, P: 72-77
RAS–MAPK–MSK1 pathway modulates ataxin 1 protein levels and toxicity in SCA1

Cross-species genetic screens reveal that decreased mitogen-activated protein kinase signalling reduces polyglutamine-expanded ataxin 1 levels and toxicity in models of spinocerebellar ataxia type 1.

Jeehye Park
Ismael Al-Ramahi
Huda Y. Zoghbi
Research29 May 2013
Nature

Volume: 498, P: 325-331
Preassembled zinc-finger arrays for rapid construction of ZFNs

Seokjoong Kim
Mi Jung Lee
Jin-Soo Kim
Correspondence29 Dec 2010
Nature Methods

Volume: 8, P: 7
Correction: Adnp-mutant mice with cognitive inflexibility, CaMKIIα hyperactivity, and synaptic plasticity deficits

Heejin Cho
Taesun Yoo
Eunjoon Kim
Amendments and CorrectionsOpen Access21 Jul 2023
Molecular Psychiatry

Volume: 28, P: 3563
Automated system for establishing standard radiation dose–response curves and dose estimation for the Korean population

Su Jung Oh
Min Ho Jeong
Wol Soon Jo
ResearchOpen Access27 Mar 2025
Scientific Reports

Volume: 15, P: 1-13
Adnp-mutant mice with cognitive inflexibility, CaMKIIα hyperactivity, and synaptic plasticity deficits

Heejin Cho
Taesun Yoo
Eunjoon Kim
ResearchOpen Access26 Jun 2023
Molecular Psychiatry

Volume: 28, P: 3548-3562
Lithium normalizes ASD-related neuronal, synaptic, and behavioral phenotypes in DYRK1A-knockin mice

Junyeop Daniel Roh
Mihyun Bae
Eunjoon Kim
ResearchOpen Access05 Dec 2024
Molecular Psychiatry

Volume: 30, P: 2584-2596
Loss of the dermis zinc transporter ZIP13 promotes the mildness of fibrosarcoma by inhibiting autophagy

Mi-Gi Lee
Min-Ah Choi
Bum-Ho Bin
ResearchOpen Access21 Oct 2019
Scientific Reports

Volume: 9, P: 1-11
Dysbiosis of the initial stool microbiota increases the risk of developing necrotizing enterocolitis or feeding intolerance in newborns

Hyojin Chae
Sae Yun Kim
Young-Ah Youn
ResearchOpen Access18 Oct 2024
Scientific Reports

Volume: 14, P: 1-10
Formation of visual memories controlled by gamma power phase-locked to alpha oscillations

Hyojin Park
Dong Soo Lee
Ole Jensen
ResearchOpen Access16 Jun 2016
Scientific Reports

Volume: 6, P: 1-10
Gating of memory encoding of time-delayed cross-frequency MEG networks revealed by graph filtration based on persistent homology

Jarang Hahm
Hyekyoung Lee
Dong Soo Lee
ResearchOpen Access07 Feb 2017
Scientific Reports

Volume: 7, P: 1-16
Matrix metalloproteinase 11 (MMP11) in macrophages promotes the migration of HER2-positive breast cancer cells and monocyte recruitment through CCL2–CCR2 signaling

The authors demonstrate that matrix metalloproteinase 11 (MMP11) expression in mononuclear inflammatory cells (predominantly macrophages) is an independent negative prognostic factor in breast cancer, whereas tumoral MMP11 expression is not associated with patient survival. This study also shows that MMP11-overexpressing macrophages promote the migration of HER2-positive breast cancer cells and monocyte recruitment through CCL2-CCR2 signaling, suggesting a pro-tumoral role of MMP11 in macrophages in HER2-positive breast cancer through interaction with cancer cells and other cells in the tumor microenvironment.

Shin Ung Kang
Soo Youn Cho
Mi Jeong Kwon
Research13 Nov 2021
Laboratory Investigation

Volume: 102, P: 376-390
Imperceptive and reusable dermal surface EMG for lower extremity neuro-prosthetic control and clinical assessment

Jaeu Park
Jinwoong Jeong
Sanghoon Lee
ResearchOpen Access25 Oct 2023
npj Flexible Electronics

Volume: 7, P: 1-11
The PFC-LH-VTA pathway contributes to social deficits in IRSp53-mutant mice

Young Woo Noh
Yangsik Kim
Eunjoon Kim
ResearchOpen Access20 Sept 2023
Molecular Psychiatry

Volume: 28, P: 4642-4654
Dicentric chromosome assay using a deep learning-based automated system

Soo Kyung Jeong
Su Jung Oh
Wol Soon Jo
ResearchOpen Access21 Dec 2022
Scientific Reports

Volume: 12, P: 1-10
Repeated ketamine anesthesia during neurodevelopment upregulates hippocampal activity and enhances drug reward in male mice

Juvenile mice treated with ketamine at anesthetic doses develop sex-specific differences in conditioned place-preference behavior and neuronal excitability, suggesting that repeated ketamine exposure might influence drug reward behavior later in life.

Jianchen Cui
Xianshu Ju
Woosuk Chung
ResearchOpen Access15 Jul 2022
Communications Biology

Volume: 5, P: 1-12
Shaping and silane coating of a diamine-grafted metal-organic framework for improved CO₂ capture

Metal organic frameworks (MOFs) are promising for CO₂ capture. Here, the Mg₂(dobpdc) MOF is synthesized as micron-sized beads with a silane coating resulting in > 11 wt% CO₂ absorption, which is retained after three days in a humid environment at 140 °C.

Jong Hyeak Choe
Jeoung Ryul Park
Chang Seop Hong
ResearchOpen Access04 Jan 2021
Communications Materials

Volume: 2, P: 1-8
Novel Alzheimer’s disease risk variants identified based on whole-genome sequencing of APOE ε4 carriers

Jong-Ho Park
Inho Park
Jong-Won Kim
ResearchOpen Access19 May 2021
Translational Psychiatry

Volume: 11, P: 1-12
Interpretation of EBV infection in pan-cancer genome considering viral life cycle: LiEB (Life cycle of Epstein-Barr virus)

Hyojin Song
Yoojoo Lim
Youngil Koh
ResearchOpen Access05 Mar 2019
Scientific Reports

Volume: 9, P: 1-10
Deficiency of Capicua disrupts bile acid homeostasis

Eunjeong Kim
Sungjun Park
Yoontae Lee
ResearchOpen Access05 Feb 2015
Scientific Reports

Volume: 5, P: 1-8

Search

Meso–macroporous hydrogel for direct litre-scale isolation of extracellular vesicles

Responsive nematic gels from the self-assembly of aqueous nanofibres

Hybrid tungsten oxyselenide/graphene electrodes for near-lossless 2D semiconductor phase modulators

A biodegradable and self-deployable electronic tent electrode for brain cortex interfacing

Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice

Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice

Structural basis for assembly and disassembly of the IGF/IGFBP/ALS ternary complex

Early postnatal serotonin modulation prevents adult-stage deficits in Arid1b-deficient mice through synaptic transcriptional reprogramming

Adaptive self-healing electronic epineurium for chronic bidirectional neural interfaces

TRRUST: a reference database of human transcriptional regulatory interactions

Synthesis of Ordered Mesoporous Phenanthrenequinone-Carbon via π-π Interaction-Dependent Vapor Pressure for Rechargeable Batteries

An amphibious artificial vision system with a panoramic visual field

SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties

RAS–MAPK–MSK1 pathway modulates ataxin 1 protein levels and toxicity in SCA1

Preassembled zinc-finger arrays for rapid construction of ZFNs

Correction: Adnp-mutant mice with cognitive inflexibility, CaMKIIα hyperactivity, and synaptic plasticity deficits

Automated system for establishing standard radiation dose–response curves and dose estimation for the Korean population

Adnp-mutant mice with cognitive inflexibility, CaMKIIα hyperactivity, and synaptic plasticity deficits

Lithium normalizes ASD-related neuronal, synaptic, and behavioral phenotypes in DYRK1A-knockin mice

Loss of the dermis zinc transporter ZIP13 promotes the mildness of fibrosarcoma by inhibiting autophagy

Dysbiosis of the initial stool microbiota increases the risk of developing necrotizing enterocolitis or feeding intolerance in newborns

Formation of visual memories controlled by gamma power phase-locked to alpha oscillations

Gating of memory encoding of time-delayed cross-frequency MEG networks revealed by graph filtration based on persistent homology

Matrix metalloproteinase 11 (MMP11) in macrophages promotes the migration of HER2-positive breast cancer cells and monocyte recruitment through CCL2–CCR2 signaling

Imperceptive and reusable dermal surface EMG for lower extremity neuro-prosthetic control and clinical assessment

The PFC-LH-VTA pathway contributes to social deficits in IRSp53-mutant mice

Dicentric chromosome assay using a deep learning-based automated system

Repeated ketamine anesthesia during neurodevelopment upregulates hippocampal activity and enhances drug reward in male mice

Shaping and silane coating of a diamine-grafted metal-organic framework for improved CO₂ capture

Novel Alzheimer’s disease risk variants identified based on whole-genome sequencing of APOE ε4 carriers

Interpretation of EBV infection in pan-cancer genome considering viral life cycle: LiEB (Life cycle of Epstein-Barr virus)

Deficiency of Capicua disrupts bile acid homeostasis

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