Nature Search

Global, regional and national burden of ischemic heart disease attributable to suboptimal diet, 1990–2023: a Global Burden of Disease study

Global Burden of Disease analysis found that in 2023, suboptimal diet was estimated to be responsible for 4 million deaths and 97 million morbidity burdens from ischemic heart disease.

Sooji Lee
Hayeon Lee
Dong Keon Yon
Research30 Mar 2026
Nature Medicine

P: 1-25
Geometric morphometrics based diagnostic model for Skeletal Class III patients

Faria-Teixeira, Carvalho et al. present a machine learning model designed to identify novel diagnostic groups for skeletal Class III malocclusion using cephalometric radiographs from 655 patients. The presented model identifies six distinct subphenotypes that generalise across ethnicities and correlate with treatment selection.

Maria Cristina Faria-Teixeira
Inês M. N. Carvalho
Alejandro Iglesias-Linares
ResearchOpen Access14 Apr 2026
Communications Medicine

P: 1-12
Neuroepithelial VIP–VIPR1 interactions differentially control enteric type 1 and type 2 immunity

Veiga-Fernandes and colleagues show that neuroepithelial interactions differentially control type 1 and type 2 enteric immunity via VIP–VIPR1 signaling.

Roksana M. Pirzgalska
Beatriz Henriques-Alves
Henrique Veiga-Fernandes
Research24 Nov 2025
Nature Immunology

Volume: 26, P: 2244-2255
Missense variant in TTBK2 kinase domain causes loss of function and impaired protein phosphorylation

Daniela Felício
Hugo Osório
Mariana Santos
ResearchOpen Access21 Dec 2025
Scientific Reports

Volume: 16, P: 1-19
Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

Fine-scale geospatial mapping of overweight and wasting (two components of the double burden of malnutrition) in 105 LMICs shows that overweight has increased from 5.2% in 2000 to 6.0% in children under 5 in 2017. Although overall wasting decreased over the same period, most countries are not on track to meet the World Health Organization’s Global Nutrition Target of <5% in over half of LMICs by 2025.

Damaris K. Kinyoki
Jennifer M. Ross
Simon I. Hay
ResearchOpen Access20 Apr 2020
Nature Medicine

Volume: 26, P: 750-759
Remdesivir and corticosteroids in the treatment of hospitalized COVID-19 patients

Luís Coelho
Fatima Falcão
José Correia
ResearchOpen Access18 Mar 2023
Scientific Reports

Volume: 13, P: 1-6
Struggling with fish age, a comparison of otolith preparation techniques to unravel age and growth of boarfish, Capros aper (Linnaeus, 1758)

Maria Inês Silva
Rui Martins
Ana Rita Vieira
ResearchOpen Access31 Aug 2024
Scientific Reports

Volume: 14, P: 1-15
Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity

Macrophages undergo a Warburg-like switch from oxidative phosphorylation to glycolysis in response to inflammatory stimulus. Here the authors show that fungal melanin can trigger this switch in human macrophages by sequestering calcium in the phagosome and enabling protection against Aspergillus fumigatus infection.

Samuel M. Gonçalves
Cláudio Duarte-Oliveira
Agostinho Carvalho
ResearchOpen Access08 May 2020
Nature Communications

Volume: 11, P: 1-15
High frequency of CHD7 mutations in congenital hypogonadotropic hypogonadism

Catarina Inês Gonçalves
Filipa Marina Patriarca
Manuel Carlos Lemos
ResearchOpen Access07 Feb 2019
Scientific Reports

Volume: 9, P: 1-6
Dietary alterations modulate susceptibility to Plasmodium infection

Reactive oxygen species, most likely spawned from dietary-induced fatty acid β-oxidation, directly impact Plasmodium survival inside hepatocytes and sigificantly reduce liver infection.

Vanessa Zuzarte-Luís
João Mello-Vieira
Maria M. Mota
Research25 Sept 2017
Nature Microbiology

Volume: 2, P: 1600-1607
Probiotics reshape the coral microbiome in situ without detectable off-target effects in the surrounding environment

Pioneering coral probiotics study shows in situ application reshapes the coral microbiome, boosting beneficial bacteria and reducing pathogens without affecting surrounding seawater and sediment microbiomes.

Nathalia Delgadillo-Ordoñez
Neus Garcias-Bonet
Raquel S. Peixoto
ResearchOpen Access09 Apr 2024
Communications Biology

Volume: 7, P: 1-16
Nebulized enriched heparin improves respiratory parameters in patients with COVID-19: a phase I/II randomized and triple-blind clinical trial

Vinicius Tadeu Ramos da Silva Grillo
Matheus Bertanha
Carlos Magno Castelo Branco Fortaleza
ResearchOpen Access27 Aug 2024
Scientific Reports

Volume: 14, P: 1-12
Atomic force microscopy as a tool to evaluate the risk of cardiovascular diseases in patients

Measuring the binding force between red blood cells and fibrinogen — the protein that helps in the formation of blood clots — using an atomic force microscope can help identify patients at increased risk of cardiovascular disease.

Ana Filipa Guedes
Filomena A. Carvalho
Nuno C. Santos
Research16 May 2016
Nature Nanotechnology

Volume: 11, P: 687-692
Tryptophan-induced transcriptomic changes in the European Seabass are highly dependent on neuroendocrine-immune conditions

Diogo Peixoto
Inês Carvalho
Benjamín Costas
ResearchOpen Access10 May 2025
Scientific Reports

Volume: 15, P: 1-14
Association between ACE2 and TMPRSS2 nasopharyngeal expression and COVID-19 respiratory distress

Átila Duque Rossi
João Locke Ferreira de Araújo
Cynthia Chester Cardoso
ResearchOpen Access06 May 2021
Scientific Reports

Volume: 11, P: 1-9
Global Roadkill Data: a dataset on terrestrial vertebrate mortality caused by collision with vehicles

Clara Grilo
Tomé Neves
Eric Guinard
ResearchOpen Access31 Mar 2025
Scientific Data

Volume: 12, P: 1-14
Author Correction: Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

Damaris K. Kinyoki
Jennifer M. Ross
Simon I. Hay
Amendments and CorrectionsOpen Access02 Jul 2020
Nature Medicine

Volume: 26, P: 1308
Dietary tryptophan intervention counteracts stress-induced transcriptional changes in a teleost fish HPI axis during inflammation

Diogo Peixoto
Inês Carvalho
Rita Azeredo
ResearchOpen Access28 Mar 2024
Scientific Reports

Volume: 14, P: 1-16
Dies1/VISTA expression loss is a recurrent event in gastric cancer due to epigenetic regulation

Patrícia Oliveira
Joana Carvalho
Carla Oliveira
ResearchOpen Access10 Oct 2016
Scientific Reports

Volume: 6, P: 1-11
SARS-CoV-2 introductions and early dynamics of the epidemic in Portugal

Borges et al. study the dynamics of SARS-CoV-2 in Portugal during 2020. The authors use phylodynamic modelling to infer patterns of SARS-CoV-2 introduction into Portugal and its subsequent spread, providing a comprehensive genomic epidemiology study of the early SARS-CoV-2 epidemic in Portugal.

Vítor Borges
Joana Isidro
João Paulo Gomes
ResearchOpen Access28 Jan 2022
Communications Medicine

Volume: 2, P: 1-11
Thrombogenesis-associated genetic determinants as predictors of thromboembolism and prognosis in cervical cancer

Beatriz Vieira Neto
Valéria Tavares
Rui Medeiros
ResearchOpen Access12 Jun 2023
Scientific Reports

Volume: 13, P: 1-15
Fado, urban popular song, and intangible heritage: perceptions of authenticity and emotions in TripAdvisor reviews

Inês Carvalho
Arlindo Madeira
Teresa Palrão
ResearchOpen Access27 Jul 2023
Humanities and Social Sciences Communications

Volume: 10, P: 1-11
Rabbit derived VL single-domains as promising scaffolds to generate antibody–drug conjugates

Ana S. André
Joana N. R. Dias
Frederico Aires-da-Silva
ResearchOpen Access24 Mar 2023
Scientific Reports

Volume: 13, P: 1-14
Type 2 diabetes progression differently affects endothelial function and vascular contractility in the aorta and the pulmonary artery

Bernardete F. Melo
Jesus Prieto-Lloret
Silvia V. Conde
ResearchOpen Access15 Mar 2021
Scientific Reports

Volume: 11, P: 1-14
Maternal outcomes and risk factors for COVID-19 severity among pregnant women

Manon Vouga
Guillaume Favre
Alice Panchaud
ResearchOpen Access06 Jul 2021
Scientific Reports

Volume: 11, P: 1-11
Genetic consequences of social structure in the golden-crowned sifaka

Bárbara Parreira
Erwan Quéméré
Lounès Chikhi
ResearchOpen Access13 Aug 2020
Heredity

Volume: 125, P: 328-339
Serratia liquefaciens FG3 isolated from a metallophyte plant sheds light on the evolution and mechanisms of adaptive traits in extreme environments

Washington Luiz Caneschi
Angélica Bianchini Sanchez
Leandro Marcio Moreira
ResearchOpen Access29 Nov 2019
Scientific Reports

Volume: 9, P: 1-16
Improving breakfast patterns of portuguese children—an evaluation of ready-to-eat cereals according to the European nutrient profile model

Ana Isabel Rito
Ana Dinis
Camila Stein-Novais
Research04 Jul 2018
European Journal of Clinical Nutrition

Volume: 73, P: 465-473
A new role for anandamide: defective link between the systemic and skin endocannabinoid systems in hypertrophic human wound healing

Inês B. Correia-Sá
Cláudia M. Carvalho
Maria A. Vieira-Coelho
ResearchOpen Access07 Jul 2020
Scientific Reports

Volume: 10, P: 1-11
Natural infection by the protozoan Leptomonas wallacei impacts the morphology, physiology, reproduction, and lifespan of the insect Oncopeltus fasciatus

Luiz Ricardo C. Vasconcellos
Luiz Max F. Carvalho
Angela H. Lopes
ResearchOpen Access25 Nov 2019
Scientific Reports

Volume: 9, P: 1-13
A high-cholesterol diet promotes the intravasation of breast tumor cells through an LDL–LDLR axis

Ana Magalhães
Vanessa Cesário
Sérgio Dias
ResearchOpen Access24 Apr 2024
Scientific Reports

Volume: 14, P: 1-11
Disease-mediated bottom-up regulation: An emergent virus affects a keystone prey, and alters the dynamics of trophic webs

Pedro Monterroso
Germán Garrote
Paulo C. Alves
ResearchOpen Access31 Oct 2016
Scientific Reports

Volume: 6, P: 1-9
Age-related shift in LTD is dependent on neuronal adenosine A_2A receptors interplay with mGluR5 and NMDA receptors

Mariana Temido-Ferreira
Diana G. Ferreira
Luísa V. Lopes
ResearchOpen Access27 Jun 2018
Molecular Psychiatry

Volume: 25, P: 1876-1900
MicroRNA-27a-5p regulation by promoter methylation and MYC signaling in prostate carcinogenesis

Daniela Barros-Silva
Pedro Costa-Pinheiro
Carmen Jerónimo
ResearchOpen Access07 Feb 2018
Cell Death & Disease

Volume: 9, P: 1-15
TRSP is dispensable for the Plasmodium pre-erythrocytic phase

David Mendes Costa
Mónica Sá
Joana Tavares
ResearchOpen Access10 Oct 2018
Scientific Reports

Volume: 8, P: 1-9
At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Munib Mesinovic
Xin Ci Wong
David Zucman
ResearchOpen Access16 Jul 2024
Scientific Reports

Volume: 14, P: 1-43
ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

Ali Abbas
Sheryl Ann Abdukahil
Luis Felipe Reyes
ResearchOpen Access30 Jul 2022
Scientific Data

Volume: 9, P: 1-22

Search

Global, regional and national burden of ischemic heart disease attributable to suboptimal diet, 1990–2023: a Global Burden of Disease study

Geometric morphometrics based diagnostic model for Skeletal Class III patients

Neuroepithelial VIP–VIPR1 interactions differentially control enteric type 1 and type 2 immunity

Missense variant in TTBK2 kinase domain causes loss of function and impaired protein phosphorylation

Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

Remdesivir and corticosteroids in the treatment of hospitalized COVID-19 patients

Struggling with fish age, a comparison of otolith preparation techniques to unravel age and growth of boarfish, Capros aper (Linnaeus, 1758)

Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity

High frequency of CHD7 mutations in congenital hypogonadotropic hypogonadism

Dietary alterations modulate susceptibility to Plasmodium infection

Probiotics reshape the coral microbiome in situ without detectable off-target effects in the surrounding environment

Nebulized enriched heparin improves respiratory parameters in patients with COVID-19: a phase I/II randomized and triple-blind clinical trial

Atomic force microscopy as a tool to evaluate the risk of cardiovascular diseases in patients

Tryptophan-induced transcriptomic changes in the European Seabass are highly dependent on neuroendocrine-immune conditions

Association between ACE2 and TMPRSS2 nasopharyngeal expression and COVID-19 respiratory distress

Global Roadkill Data: a dataset on terrestrial vertebrate mortality caused by collision with vehicles

Author Correction: Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

Dietary tryptophan intervention counteracts stress-induced transcriptional changes in a teleost fish HPI axis during inflammation

Dies1/VISTA expression loss is a recurrent event in gastric cancer due to epigenetic regulation

SARS-CoV-2 introductions and early dynamics of the epidemic in Portugal

Thrombogenesis-associated genetic determinants as predictors of thromboembolism and prognosis in cervical cancer

Fado, urban popular song, and intangible heritage: perceptions of authenticity and emotions in TripAdvisor reviews

Rabbit derived VL single-domains as promising scaffolds to generate antibody–drug conjugates

Type 2 diabetes progression differently affects endothelial function and vascular contractility in the aorta and the pulmonary artery

Maternal outcomes and risk factors for COVID-19 severity among pregnant women

Genetic consequences of social structure in the golden-crowned sifaka

Serratia liquefaciens FG3 isolated from a metallophyte plant sheds light on the evolution and mechanisms of adaptive traits in extreme environments

Improving breakfast patterns of portuguese children—an evaluation of ready-to-eat cereals according to the European nutrient profile model

A new role for anandamide: defective link between the systemic and skin endocannabinoid systems in hypertrophic human wound healing

Natural infection by the protozoan Leptomonas wallacei impacts the morphology, physiology, reproduction, and lifespan of the insect Oncopeltus fasciatus

A high-cholesterol diet promotes the intravasation of breast tumor cells through an LDL–LDLR axis

Disease-mediated bottom-up regulation: An emergent virus affects a keystone prey, and alters the dynamics of trophic webs

Age-related shift in LTD is dependent on neuronal adenosine A_2A receptors interplay with mGluR5 and NMDA receptors

MicroRNA-27a-5p regulation by promoter methylation and MYC signaling in prostate carcinogenesis

TRSP is dispensable for the Plasmodium pre-erythrocytic phase

At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

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