Nature Search

Levels of Nitrate Reductase Activity in Inbred Lines and F₁ Hybrids in Maize

R. H. HAGEMAN
J. F. ZIESERL
EARL R. LENG
Research19 Jan 1963
Nature

Volume: 197, P: 263-265
Natural selection contributed to immunological differences between hunter-gatherers and agriculturalists

Variation in responses to bacterial and viral stimuli between Batwa rainforest hunter-gatherers and Bakiga agriculturalists from Uganda suggests population-level divergence under natural selection, with hunter-gatherers disproportionately showing signatures of positive selection.

Genelle F. Harrison
Joaquin Sanz
Luis B. Barreiro
Research29 Jul 2019
Nature Ecology & Evolution

Volume: 3, P: 1253-1264
Pb(II)-catalysed cleavage of the sugar–phosphate backbone of yeast tRNA^Phe—implications for lead toxicity and self-splicing RNA

R. S. Brown
B. E. Hingerty
A. Klug
Research01 Jun 1983
Nature

Volume: 303, P: 543-546
Molecular Weight of Rabbit and Cod Myosins

J. J. CONNELL
I. M. MACKIE
Research04 Jan 1964
Nature

Volume: 201, P: 78-79
Growth Test and Liver Storage of All-trans Vitamin A Acid and Three of its Geometric Isomers with Chicks

TH. J. DE MAN
P. H. VAN LEEUWEN
J. R. ROBORGH
Research04 Jan 1964
Nature

Volume: 201, P: 77-78
Glucagon-like peptide-1 receptor agonist in large vessel occlusion treated by reperfusion therapy—a phase 2 randomized trial

Semaglutide, a GLP-1 receptor agonist, may offer neuroprotective benefits after stroke, but its effects in large vessel occlusion (LVO) are unknown. Here the authors show, in a phase 2 randomized trial, that semaglutide is safe after endovascular therapy and may improve recovery in patients not receiving intravenous thrombolysis.

Hao Wang
Ho Ko
Bonaventure Y. Ip
ResearchOpen Access14 Dec 2025
Nature Communications

Volume: 16, P: 1-10
Observation of Million Degree Thermal Radiation from the Sun at a Wavelength of 1.5 Metres

J. L. PAWSEY
Research02 Nov 1946
Nature

Volume: 158, P: 633-634
Endogenous opiates regulate oxytocin but not vasopressin secretion from the neurohypophysis

R. J. Bicknell
G. Leng
Research08 Jul 1982
Nature

Volume: 298, P: 161-162
A single-cell atlas characterizes dysregulation of the bone marrow immune microenvironment associated with outcomes in multiple myeloma

Pilcher et al. present a single-cell transcriptomics-based immune atlas of participants with newly diagnosed multiple myeloma, reporting on the association of cell types, gene expression and intercellular interactions with disease progression phenotypes.

William C. Pilcher
Lijun Yao
Manoj Bhasin
ResearchOpen Access09 Jan 2026
Nature Cancer

Volume: 7, P: 224-246
Ionic and Hydrogen Bond Interactions Contributing to the Conformational Stability of Polynucleotides

J. BRAHMS
Ch. SADRON
Research17 Dec 1966
Nature

Volume: 212, P: 1309-1312
A distinct PP2A subunit regulates local protein phosphorylation at the axon initial segment

The existence of phosphatases specialized in regulating the axon initial segment (AIS) was unclear. Here, the authors show that a PP2A-B55 subunit is selectively enriched at the AIS and contributes to its local phospho-regulation.

Andrew P. Anderson
Sanghyun Kim
Yudong Gao
ResearchOpen Access03 Dec 2025
Nature Communications

Volume: 16, P: 1-12
X-ray transient source at high galactic latitude and suggested extragalactic identification

M. J. RICKETTS
B. A. COOKE
K. A. POUNDS
Research19 Feb 1976
Nature

Volume: 259, P: 546-547
Diminishing benefits of urban living for children and adolescents’ growth and development

The advantage of living in cities compared with rural areas with respect to height and BMI in children and adolescents has generally become smaller globally from 1990 to 2020, except in sub-Saharan Africa.

Anu Mishra
Bin Zhou
Majid Ezzati
ResearchOpen Access29 Mar 2023
Nature

Volume: 615, P: 874-883
CARD11 signaling regulates CD8⁺ T cell tumoricidal function

Here the authors use genetic mutations to alter TCR signal strength and clonal selection of exhausted CD8⁺ T cells. They implicate CARD11 signaling as a sensor of this TCR signal strength and as a regulator of antitumor function in exhausted T cells that might be targeted to enhance cancer immunotherapies.

Yu Hu
Qifan Zhao
Wei Lu
Research18 Jun 2025
Nature Immunology

Volume: 26, P: 1113-1126
Transcriptional signature in microglia associated with Aβ plaque phagocytosis

Microglia associated with Aβ plaques may have a distinct transcriptional signature compared to those in plaque-free areas of the brain in Alzheimer’s disease (AD) models. Here the authors show that amyloid plaque phagocytosis is associated with a specific microglia transcriptional signature in a mouse model of AD.

Alexandra Grubman
Xin Yi Choo
Jose M. Polo
ResearchOpen Access21 May 2021
Nature Communications

Volume: 12, P: 1-22
Early life high fructose impairs microglial phagocytosis and neurodevelopment

Exposure of mice to high fructose during gestation or early postnatal life causes decreased microglial phagocytosis during brain development and leads to anxiety-like behaviour in adolescence.

Zhaoquan Wang
Allie Lipshutz
Justin S. A. Perry
Research11 Jun 2025
Nature

Volume: 644, P: 759-768
Modulating glycosphingolipid metabolism and autophagy improves outcomes in pre-clinical models of myeloma bone disease

Here, the authors show that the glycosylceramide synthesis inhibitor and FDA approved drug Eliglustat inhibits autophagic degradation of TRAF3 which is a key step for osteoclast differentiation and thereby improves myeloma bone lesions.

Houfu Leng
Hanlin Zhang
Nicole J. Horwood
ResearchOpen Access22 Dec 2022
Nature Communications

Volume: 13, P: 1-18
Local structure of silicate glasses

G. N. Greaves
A. Fontaine
S. J. Gurman
Research22 Oct 1981
Nature

Volume: 293, P: 611-616
Reply to: Questioning the rate law in the analysis of water oxidation catalysis on haematite photoanodes

Camilo A. Mesa
Reshma R. Rao
James R. Durrant
Research09 Nov 2020
Nature Chemistry

Volume: 12, P: 1099-1101
Ovarioles as a Meristic Character in Coleoptera

J. G. ROBERTSON
Research06 Aug 1960
Nature

Volume: 187, P: 526-527
Towards a table-top microscope for nanoscale magnetic imaging using picosecond thermal gradients

Table-top measurements of magnetic structures and dynamics in thin films are typically limited by temporal or spatial resolution. Here, the authors present a heat-based spatiotemporal magnetic microscopy method based on the anomalous Nernst effect, which may potentially overcome such limits.

J. M. Bartell
D. H. Ngai
G. D. Fuchs
ResearchOpen Access30 Sept 2015
Nature Communications

Volume: 6, P: 1-7
Silencing CA1 pyramidal cells output reveals the role of feedback inhibition in hippocampal oscillations

Current approaches possibly cannot unambiguously distinguish the unique contributions of feedback inhibition versus feedforward inhibition to oscillatory events. Here authors show that a loss of CA1 pyramidal cell transmission, resulting in feedback inhibition reduction, leads to spatially triggered high-frequency oscillatory events; these events were like place cells in their spatial extent and localized to small regions in CA1.

Chinnakkaruppan Adaikkan
Justin Joseph
Thomas J. McHugh
ResearchOpen Access11 Mar 2024
Nature Communications

Volume: 15, P: 1-15
The role of metamorphic decarbonation reactions in returning strontium to the silicate sediment mass

M. J. Bickle
Research24 Feb 1994
Nature

Volume: 367, P: 699-704
Abnormal Solar Radiation on 72 Megacycles

A. C. B. LOVELL
C. J. BANWELL
Research12 Oct 1946
Nature

Volume: 158, P: 517-518
Multicellular immune ecotypes within solid tumors predict real-world therapeutic benefits with immune checkpoint inhibitors

Cellular state cooccurrence signatures, such as carcinoma ecotypes may serve as potential biomarkers of response to cancer immunotherapy, however, their clinical utility remains unexplored. Here, the authors analyse large real world immunotherapy cohorts and gene expression data and develop a predictive model for response.

Xuefeng Wang
Tingyi Li
Ahmad A. Tarhini
ResearchOpen Access13 Nov 2025
Nature Communications

Volume: 16, P: 1-13
Evolution of the 87A and 87C heat-shock loci in Drosophila

A. J. Leigh Brown
D. Ish-Horowicz
Research23 Apr 1981
Nature

Volume: 290, P: 677-682
Inferring structural variant cancer cell fraction

The authors present SVclone, a computational method for inferring the cancer cell fraction of structural variants from whole-genome sequencing data.

Marek Cmero
Ke Yuan
Christian von Mering
ResearchOpen Access05 Feb 2020
Nature Communications

Volume: 11, P: 1-15
Convergent direct and indirect cortical streams shape avoidance decisions in mice via the midline thalamus

How prefronto-thalamic circuits shape emotional and motivated behaviors are not fully understood. Here authors report a top-down modulation in mouse prefronto-thalamic projections. The prelimbic area influences avoidance via direct and indirect pathways, revealing distinctive intrathalamic dynamics essential for complex behavior integration.

Jun Ma
John J. O’Malley
Mario A. Penzo
ResearchOpen Access04 Aug 2024
Nature Communications

Volume: 15, P: 1-17
Loss of Methyl Tritium from [³H] Acetate in Rumen Fluid

R. A. LENG
G. J. LEONARD
Research14 Aug 1965
Nature

Volume: 207, P: 760-761
Evolutionary trajectories of IDH-mutant astrocytoma identify molecular grading markers related to cell cycling

Vallentgoed et al. integrate clinical and multiomic data from persons with matched initial and recurrent IDH-mutant astrocytomas to identify progression-associated mechanisms and report a DNA methylation-based signature associated with survival.

Wies R. Vallentgoed
Youri Hoogstrate
Pim J. French
Research19 Aug 2025
Nature Cancer

Volume: 6, P: 1693-1713
Atomic structure of the MAP kinase ERK2 at 2.3 Å resolution

Faming Zhang
Arne Strand
Elizabeth J. Goldsmith
Research24 Feb 1994
Nature

Volume: 367, P: 704-711
Autogenous Necrosis in an Antirrhinum Species Hybrid

B. J. HARRISON
Research06 Aug 1960
Nature

Volume: 187, P: 527-528
Deposition and drying dynamics of liquid crystal droplets

When particle-laden drops evaporate, coffee ring patterns form which can affect particle deposition. Here Davidsonet al. show that unlike previously investigated drops, the flows in drying drops of liquid crystals are driven by an increase in surface tension due to liquid crystal concentration.

Zoey S. Davidson
Yongyang Huang
A. G. Yodh
ResearchOpen Access30 May 2017
Nature Communications

Volume: 8, P: 1-7
Inhibition of Viral Multiplication by Chemically Methylated DNA from the Host Cells

G. BECK
J. P. EBEL
L. COLOBERT
Research28 Nov 1970
Nature

Volume: 228, P: 859-860
Electron-transparent Zone of Mycobacteria may be a Defence Mechanism

P. DRAPER
R. J. W. REES
Research28 Nov 1970
Nature

Volume: 228, P: 860-861
Glucose-6-phosphate Dehydrogenase and Potassium Concentration in Sheep Erythrocytes

J. H. KOCH
Research28 Dec 1963
Nature

Volume: 200, P: 1334-1335
Prostaglandins: Their Disappearance from and Release into the Circulation

S. H. FERREIRA
J. R. VANE
Research02 Dec 1967
Nature

Volume: 216, P: 868-873
A New Development in Aids for Sub-normal Vision

J. LEDERER
Research20 Nov 1954
Nature

Volume: 174, P: 977-978
A novel DNA structure induced by the anticancer bisplatinum compound crosslinked to a GpC site in DNA

Danzhou Yang
Stella S. G. E. van Boom
Andrew H.-J. Wang
Research01 Jul 1995
Nature Structural Biology

Volume: 2, P: 577-586
A structural role for hormone in the thyroid hormone receptor

Richard L. Wagner
James W. Apriletti
Robert J. Fletterick
Research14 Dec 1995
Nature

Volume: 378, P: 690-697
Possible role for poly(A) as an inhibitor of endonuclease activity in eukaryotic cells

CARL C. LEVY
MORTON SCHMUKLER
ROBERT G. DORR
Research24 Jul 1975
Nature

Volume: 256, P: 340-342
A Jamaica Drift Fruit

J. H. HART
Research09 Apr 1896
Nature

Volume: 53, P: 534-535
Magnesium as a Toxic Element

J. PROCTOR
Research15 Aug 1970
Nature

Volume: 227, P: 742-743
Combined burden and functional impact tests for cancer driver discovery using DriverPower

Analysis of cancer genome sequencing data has enabled the discovery of driver mutations. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium the authors present DriverPower, a software package that identifies coding and non-coding driver mutations within cancer whole genomes via consideration of mutational burden and functional impact evidence.

Shimin Shuai
Federico Abascal
Christian von Mering
ResearchOpen Access05 Feb 2020
Nature Communications

Volume: 11, P: 1-12
Long-term change in body composition following intentional weight loss and its effect on physical function

Kacey Chae
Xiaoyan Leng
Denise K. Houston
ResearchOpen Access23 Dec 2025
International Journal of Obesity

P: 1-8
An oxysterol signalling pathway mediated by the nuclear receptor LXRα

Bethany A. Janowski
Patricia J. Willy
David J. Mangelsdorf
Research24 Oct 1996
Nature

Volume: 383, P: 728-731
Crystal Structure of L-Serine Phosphate

G. H. McCALLUM
J. MONTEATH ROBERTSON
G. A. SIM
Research12 Dec 1959
Nature

Volume: 184, P: 1863-1864
A water-vapour giga-maser in the active galaxy TXFS2226 – 184

Anton M. Koekemoer
Christian Henkel
Robert Antonucci
Research14 Dec 1995
Nature

Volume: 378, P: 697-699
Genomic basis for RNA alterations in cancer

Integrative analyses of transcriptome and whole-genome sequencing data for 1,188 tumours across 27 types of cancer are used to provide a comprehensive catalogue of RNA-level alterations in cancer.

Claudia Calabrese
Natalie R. Davidson
Christian von Mering
ResearchOpen Access05 Feb 2020
Nature

Volume: 578, P: 129-136
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes

Analyses of 2,658 whole genomes across 38 types of cancer identify the contribution of non-coding point mutations and structural variants to driving cancer.

Esther Rheinbay
Morten Muhlig Nielsen
Christian von Mering
ResearchOpen Access05 Feb 2020
Nature

Volume: 578, P: 102-111

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