TRPC3/6/7 are DAG-activated cation channels. The authors report structures of human TRPC3 in complex with DAG or synthetic activators 4n and GSK1702934A. These results lead to the identification of monoacylglycerols as endogenous activators of TRPC3/6/7 channels.
- Yikun Chen
- Jiahe Zang
- Lei Chen
