Conventional homogeneous strategies for the synthesis of deuterated alcohols — valuable synthetic targets due to their roles in pharmaceuticals, materials, and mechanistic studies — present limitations in terms of cost and catalyst recovery, with heterogeneous catalysis providing recyclability and enhanced scalability. In this Perspective, the authors discuss the evolution of heterogeneous catalytic systems into scalable and efficient platforms for deuterated alcohol synthesis, highlighting new directions for sustainable isotope incorporation.
- Jing-Jing Tang
- Shu-Xian Li
- Botao Qiao
