Nature Search

Accurate, non-destructive, and high-throughput age estimation for Golden perch (Macquaria ambigua spp.) using DNA methylation

Benjamin Mayne
Tom Espinoza
Sharon Marshall
ResearchOpen Access12 Jun 2023
Scientific Reports

Volume: 13, P: 1-8
Ecological and social pressures drive same-sex sexual behaviour in non-human primates

Phylogenetic regression and structural equation modelling of environmental, social and life history traits across the primate clade indicates correlates for same-sex sexual behaviour (SSB), and suggests that while environmental and life history traits tend to influence SSB indirectly, social complexity directly promotes its occurrence.

Chloë Coxshall
Miles Nesbit
Vincent Savolainen
Research12 Jan 2026
Nature Ecology & Evolution

Volume: 10, P: 330-341
APOE4 to APOE2 allelic switching in mice improves Alzheimer’s disease-related metabolic signatures, neuropathology and cognition

Using a mouse model enabling an inducible ‘switch’, Golden et al. show that an astrocyte-specific replacement of the Alzheimer’s risk gene APOE4 with protective APOE2 alters metabolism and gene expression, reducing amyloid pathology and gliosis.

Lesley R. Golden
Dahlia S. Siano
Lance A. Johnson
ResearchOpen Access11 Nov 2025
Nature Neuroscience

Volume: 28, P: 2461-2475
Systematic discovery of recombinases for efficient integration of large DNA sequences into the human genome

Screening recombinases identifies tools for inserting large sequences into the human genome.

Matthew G. Durrant
Alison Fanton
Patrick D. Hsu
ResearchOpen Access10 Oct 2022
Nature Biotechnology

Volume: 41, P: 488-499
Arabidopsis and maize terminator strength is determined by GC content, polyadenylation motifs and cleavage probability

Using Plant STARR-seq, Gorjifard et al analyzed over 50,000 plant terminators and found that plant terminator activity is species-specific, highly dependent on GC content and polyadenylation motifs, and they developed a computational model to predict terminator strength and create optimized synthetic terminators.

Sayeh Gorjifard
Tobias Jores
Christine Queitsch
ResearchOpen Access12 Jul 2024
Nature Communications

Volume: 15, P: 1-21
The regulatory potential of transposable elements in maize

Long-read chromatin assay reveals (1) a novel class of accessible chromatin regions, (2) accessibility within individual LTR retrotransposons and (3) the relationship between diffuse accessibility, gene body methylation and hAT transposon insertion.

Kerry L. Bubb
Morgan O. Hamm
Christine Queitsch
Research13 May 2025
Nature Plants

Volume: 11, P: 1181-1192
Synthetic promoter designs enabled by a comprehensive analysis of plant core promoters

A massively parallel reporter assay was used to measure the activity of nearly complete sets of promoters from Arabidopsis, maize and sorghum in two assay systems, uncovering the sequence features affecting promoter strength and facilitating promoter strength prediction and synthetic design.

Tobias Jores
Jackson Tonnies
Christine Queitsch
Research03 Jun 2021
Nature Plants

Volume: 7, P: 842-855
SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape

A survey of SARS-CoV-2 RBD antibodies identifies those with activity against diverse SARS-CoV-2 variants and SARS-related coronaviruses, highlighting epitopes and features to prioritize in antibody and vaccine development.

Tyler N. Starr
Nadine Czudnochowski
Gyorgy Snell
Research14 Jul 2021
Nature

Volume: 597, P: 97-102
Quasi one-dimensional band dispersion and surface metallization in long-range ordered polymeric wires

Polymerization on surfaces is an emerging approach for producing graphene nanoribbons with a tunable bandgap, a promising material for carbon-based electronics. Here, Vasseur et al.show quasi-one-dimensional band structure of a model semiconducting polymer synthesized directly on a supporting surface.

Guillaume Vasseur
Yannick Fagot-Revurat
Dmitrii F. Perepichka
ResearchOpen Access04 Jan 2016
Nature Communications

Volume: 7, P: 1-9
Neurotoxic amyloidogenic peptides in the proteome of SARS-COV2: potential implications for neurological symptoms in COVID-19

Here the authors report the formation of toxic clumps of protein, similar to amyloid assemblies found in Alzheimer’s disease and suggest their possible role for some of the neurological symptoms of long-COVID.

Mirren Charnley
Saba Islam
Nicholas P. Reynolds
ResearchOpen Access13 Jun 2022
Nature Communications

Volume: 13, P: 1-11
Immunogenicity and efficacy of mRNA COVID-19 vaccine MRT5500 in preclinical animal models

Kirill V. Kalnin
Timothy Plitnik
Danilo Casimiro
ResearchOpen Access19 Apr 2021
npj Vaccines

Volume: 6, P: 1-12
A combinatorial approach to the discovery and optimization of luminescent materials

Earl Danielson
Josh H. Golden
Xin Di Wu
Research30 Oct 1997
Nature

Volume: 389, P: 944-948
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA

Measurements of subclonal expansion of ctDNA in the plasma before surgery may enable the prediction of future metastatic subclones, offering the possibility for early intervention in patients with non-small-cell lung cancer.

Christopher Abbosh
Alexander M. Frankell
Charles Swanton
Research13 Apr 2023
Nature

Volume: 616, P: 553-562
Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

Openshaw and colleagues find myeloid inflammation and complement activation signatures in patients with long COVID who were previously hospitalized.

Felicity Liew
Claudia Efstathiou
J. Eunice Zhang
ResearchOpen Access08 Apr 2024
Nature Immunology

Volume: 25, P: 607-621
Deconstructing synthetic biology across scales: a conceptual approach for training synthetic biologists

Developing biotechnologies to address society’s challenges requires integrating concepts across disciplines, posing challenges to educating students with diverse expertise. In this Perspective the authors create a framework for synthetic biology training that deconstructs biotechnologies across spatial scales.

Ashty S. Karim
Dylan M. Brown
Julius B. Lucks
ReviewsOpen Access26 Jun 2024
Nature Communications

Volume: 15, P: 1-14
The expanding network of mineral chemistry throughout earth history reveals global shifts in crustal chemistry during the Proterozoic

Eli K. Moore
Josh J. Golden
Stephanie J. Spielman
ResearchOpen Access23 Mar 2022
Scientific Reports

Volume: 12, P: 1-9

Search

Accurate, non-destructive, and high-throughput age estimation for Golden perch (Macquaria ambigua spp.) using DNA methylation

Ecological and social pressures drive same-sex sexual behaviour in non-human primates

APOE4 to APOE2 allelic switching in mice improves Alzheimer’s disease-related metabolic signatures, neuropathology and cognition

Systematic discovery of recombinases for efficient integration of large DNA sequences into the human genome

Arabidopsis and maize terminator strength is determined by GC content, polyadenylation motifs and cleavage probability

The regulatory potential of transposable elements in maize

Synthetic promoter designs enabled by a comprehensive analysis of plant core promoters

SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape

Quasi one-dimensional band dispersion and surface metallization in long-range ordered polymeric wires

Neurotoxic amyloidogenic peptides in the proteome of SARS-COV2: potential implications for neurological symptoms in COVID-19

Immunogenicity and efficacy of mRNA COVID-19 vaccine MRT5500 in preclinical animal models

A combinatorial approach to the discovery and optimization of luminescent materials

Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA

Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

Deconstructing synthetic biology across scales: a conceptual approach for training synthetic biologists

The expanding network of mineral chemistry throughout earth history reveals global shifts in crustal chemistry during the Proterozoic

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