Cell therapy has emerged in the past 20 years as a promising avenue for cardiac repair and regeneration. In this Review, Zhang and colleagues provide an overview of the evolution of cell-based and cell product-based therapies for the treatment of heart failure, including challenges and lessons learned, and summarize ongoing clinical trials on the feasibility of novel or underexplored treatment protocols.
- Jianyi Jay Zhang
- Steven M. Pogwizd
- Philippe Menasché
