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Showing 1–50 of 143 results

Advanced filters: Author: Kenji Tamura Clear advanced filters

Disentangling multiple gas kinematic drivers in the Perseus galaxy cluster

Kinematic measurements of the Perseus galaxy cluster reveal two drivers of gas motions: a small-scale driver in the inner core associated with black-hole feedback and a large-scale driver in the outer core powered by mergers.

Marc Audard
Hisamitsu Awaki
Elena Bellomi
Research28 Jan 2026
Nature

P: 1-5
A non-spike nucleocapsid R204P mutation in SARS-CoV-2 Omicron XEC enhances inflammation and pathogenicity

SARS-CoV-2 Omicron XEC variant, a recombinant of JN.1 progeny, shows increased viral fitness and pathogenicity. Here, the authors show that the nucleocapsid mutation R204P enhances inflammation and suggest a growing role of non-spike mutations in viral evolution.

Shuhei Tsujino
Masumi Tsuda
Miki Kawano
ResearchOpen Access14 Dec 2025
Nature Communications

Volume: 17, P: 1-13
Kluyveromyces lactis killer toxin inhibits adenylate cyclase of sensitive yeast cells

Yuji Sugisaki
Norio Gunge
Gakuzo Tamura
Research04 Aug 1983
Nature

Volume: 304, P: 464-466
Infra-red Spectra of Acetylproline N-Methylamide and the Configuration of a Proline Residue in a Polypeptide Chain

SAN-ICHIRO MIZUSHIMA
TAKEHIKO SHIMANOUCHI
KAZUO KUROSAKI
Research21 Jun 1952
Nature

Volume: 169, P: 1058-1059
Prognostic significance of Claudin18.2 expression in patients with gastric cancer

Yuichiro Miki
Mami Yoshii
Kiyoshi Maeda
ResearchOpen Access07 Nov 2025
Scientific Reports

Volume: 15, P: 1-8
Virological characteristics of the SARS-CoV-2 Omicron XBB.1.5 variant

XBB.1.5 of SARS-CoV-2 is a descendant of XBB.1 and has mutations in spike and ORF8, making it more infectious to humans. Here, the authors examined in detail the differences in virological properties of the two variants.

Tomokazu Tamura
Takashi Irie
Takasuke Fukuhara
ResearchOpen Access08 Feb 2024
Nature Communications

Volume: 15, P: 1-17
Chlorine and potassium enrichment in the Cassiopeia A supernova remnant

XRISM observations show the presence of odd-numbered elements chlorine and potassium in Cas A. These findings suggest that stellar activity plays an important role in cosmic chemical evolution, enriching space with elements vital for planets and life.

Marc Audard
Hisamitsu Awaki
Manan Agarwal
ResearchOpen Access04 Dec 2025
Nature Astronomy

Volume: 10, P: 144-153
Cloning of a new cytokine that induces IFN-γ production by T cells

Haruki Okamura
Hiroko Tsutsui
Masashi Kurimoto
Research02 Nov 1995
Nature

Volume: 378, P: 88-91
Electromagnetic vibration process for producing bulk metallic glasses

Takuya Tamura
Kenji Amiya
Kenji Miwa
Research06 Mar 2005
Nature Materials

Volume: 4, P: 289-292
Pexophagy suppresses ROS-induced damage in leaf cells under high-intensity light

Pexophagy plays a pivotal role in the selective removal of ROS-generating peroxisomes, which protects plants from oxidative damage during photosynthesis under high-intensity light.

Kazusato Oikawa
Shino Goto-Yamada
Mikio Nishimura
ResearchOpen Access05 Dec 2022
Nature Communications

Volume: 13, P: 1-17
The association of reproductive history with hypertension and obesity according to menopausal status: the J-MICC Study

Mizuki Ohashi
Katsuyuki Miura
Hiroaki Ikezaki
Research14 Jan 2022
Hypertension Research

Volume: 45, P: 708-714
Spatial dynamics of CD39⁺CD8⁺ exhausted T cell reveal tertiary lymphoid structures-mediated response to PD-1 blockade in esophageal cancer

Immune checkpoint blockade (ICB) benefits esophageal squamous cell cancer, but the immune cell mediators remain unclear. Here the author show, by imaging mass cytometry, that CD39⁺CD8⁺ exhausted cells are present abundantly in both tertiary lymphoid tissue and tumor and correlate with responses to ICB.

Kenro Tanoue
Hirofumi Ohmura
Eishi Baba
ResearchOpen Access19 Oct 2024
Nature Communications

Volume: 15, P: 1-18
Doppler Echocardiographic Evaluation of Left Ventricular Output and Left Ventricular Diastolic Filling Changes in the First Day of Life

Kenji Harada
Terukazu Shiota
Goro Takada
Research01 Apr 1994
Pediatric Research

Volume: 35, P: 506-509
Lifetime risk, sex and age differences in annual incidence of ocular motor cranial nerve palsy in Japan for 2019

Miyata et al. examine the incidence rates and lifetime risk of ocular motor cranial nerve palsy (OMCNP) in in a nationwide, population-based cohort study in Japan for 2019. Finding reveals that OMCNP incidence rate increases with age and is higher in men, and that approximately one in 100 individuals is affected in their lifetime.

Manabu Miyata
Ai Kido
Akitaka Tsujikawa
ResearchOpen Access19 Jul 2025
Communications Medicine

Volume: 5, P: 1-6
Germline or somatic mutations in genes encoding microRNAs as biomarkers predicting the risk of adult T-cell leukemia/lymphoma

Shimon Nakashima
Masataka Nakano
Miki Nakajima
Research20 Oct 2025
Journal of Human Genetics

P: 1-8
Glycan sulfation patterns define autophagy flux at axon tip via PTPRσ-cortactin axis

Sulfation of chondroitin sulfate and heparan sulfate dictates their abilities to promote axon growth via regulating the binding to the phosphatase PTPRσ and the consequences on phosphorylation of the cortactin component of the autophagy machinery.

Kazuma Sakamoto
Tomoya Ozaki
Kenji Kadomatsu
Research06 May 2019
Nature Chemical Biology

Volume: 15, P: 699-709
Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants

XBB is the first recombinant, globally dominant variant of SARS-CoV-2. Here, the authors examine the variant’s origins and virological properties, showing it is the first example of SARS-CoV-2 improving its fitness through recombination.

Tomokazu Tamura
Jumpei Ito
Kei Sato
ResearchOpen Access16 May 2023
Nature Communications

Volume: 14, P: 1-20
Endoplasmic reticulum-derived bodies enable a single-cell chemical defense in Brassicaceae plants

Kenji Yamada et al. describe a single-cell chemical defense strategy in Brassicaceae plants that requires formation of endoplasmic reticulum-derived organelles for the accumulation of β-glucosidases. They find that seedlings lacking a specific β-glucosidase lose their resistance to predation by woodlice.

Kenji Yamada
Shino Goto-Yamada
Ikuko Hara-Nishimura
ResearchOpen Access14 Jan 2020
Communications Biology

Volume: 3, P: 1-10
Stratified wind from a super-Eddington X-ray binary is slower than expected

The XRISM Resolve spectrum of the galactic neutron star X-ray binary, GX 13+1, reveals one of the densest winds ever seen in absorption lines.

Marc Audard
Hisamitsu Awaki
Missagh Mehdipour
ResearchOpen Access17 Sept 2025
Nature

Volume: 646, P: 57-61
Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic leukemia

The molecular heterogeneity of KMT2A-rearranged infant acute lymphoblastic leukemia (ALL) remains poorly characterised. Here, the authors perform multi-omics analysis for 84 ALL patients and suggest 5 distinct subgroups for risk stratification and personalised treatment.’

Tomoya Isobe
Masatoshi Takagi
Junko Takita
ResearchOpen Access30 Aug 2022
Nature Communications

Volume: 13, P: 1-16
ERRγ enhances cardiac maturation with T-tubule formation in human iPSC-derived cardiomyocytes

Cardiomyocytes (CMs) derived from human induced pluripotent stem cells (hiPSCs) suffer from limited maturation. Here the authors identify ERRγ agonist as a factor that enhances cardiac morphological, metabolic, contractile and electrical maturation of hiPSC-derived CMs with T-tubule formation.

Kenji Miki
Kohei Deguchi
Yoshinori Yoshida
ResearchOpen Access21 Jun 2021
Nature Communications

Volume: 12, P: 1-15
Convergent evolution of SARS-CoV-2 Omicron subvariants leading to the emergence of BQ.1.1 variant

Recent Omicron SARS-CoV-2 subvariants independently acquire 5 key Spike mutations. Here, the authors evaluate the evolutionary importance of the 5 mutations and characterize the virological properties of variant BQ.1.1 harboring all 5 mutations.

Jumpei Ito
Rigel Suzuki
Kei Sato
ResearchOpen Access11 May 2023
Nature Communications

Volume: 14, P: 1-20
A protein language model for exploring viral fitness landscapes

Ito et al. present CoVFit, an AI model that predicts variant fitness (transmissibility) from spike protein sequences alone. They further demonstrate its utility in forecasting viral evolution via single amino acid mutations.

Jumpei Ito
Adam Strange
Kei Sato
ResearchOpen Access13 May 2025
Nature Communications

Volume: 16, P: 1-16
Synthesis of Phenolic Polymer-Coated Gold Nanoparticles

Tomoki Ogoshi
Kenji Umeda
Yoshiaki Nakamoto
Research12 Aug 2008
Polymer Journal

Volume: 40, P: 942-943
Structural basis for receptor-binding domain mobility of the spike in SARS-CoV-2 BA.2.86 and JN.1

JN.1 lineage is a globally dominant variant of SARS-CoV-2. Here, the authors examine structural insights into the BA.2.86 and JN.1 spike dynamics to help understand the mechanisms underlying SARS-CoV-2 infection and its neutralizing-antibody evasion.

Hisano Yajima
Yuki Anraku
Takao Hashiguchi
ResearchOpen Access07 Oct 2024
Nature Communications

Volume: 15, P: 1-14
A genome-wide association study on fish consumption in a Japanese population—the Japan Multi-Institutional Collaborative Cohort study

Taro Suzuki
Yasuyuki Nakamura
Toshiro Takezaki
Research07 Sept 2020
European Journal of Clinical Nutrition

Volume: 75, P: 480-488
Association of potential biomarkers with clinical outcomes in metastatic triple-negative breast cancer treated with pembrolizumab or chemotherapy

Javier Cortes
Oleg Lipatov
Eric P. Winer
ResearchOpen Access02 Oct 2025
npj Breast Cancer

Volume: 11, P: 1-10
High-throughput functional evaluation of BRCA2 variants of unknown significance

Many germline variants are found in the BRCA2 gene, some of which pre-dispose women to breast and ovarian cancer. Here, the authors develop a method to determine the functional significance of BRCA2 variants and show that it is comparable to the IARC system of classifying variants.

Masachika Ikegami
Shinji Kohsaka
Hiroyuki Mano
ResearchOpen Access22 May 2020
Nature Communications

Volume: 11, P: 1-13
TRPA1-mediated repellency behavior in the red flour beetle Tribolium castaneum

Kenji Shimomura
Soshi Ino
Motohiro Tomizawa
ResearchOpen Access10 Sept 2022
Scientific Reports

Volume: 12, P: 1-9
Brain metastatic cancer cells release microRNA-181c-containing extracellular vesicles capable of destructing blood–brain barrier

A key event during metastasis to the brain is the migration of cancer cells through the blood–brain barrier (BBB). Here the authors show that cancer-cell-derived extracellular vesicles promote metastasis by promoting BBB breaching.

Naoomi Tominaga
Nobuyoshi Kosaka
Takahiro Ochiya
ResearchOpen Access01 Apr 2015
Nature Communications

Volume: 6, P: 1-12
Loss of microRNA-27b contributes to breast cancer stem cell generation by activating ENPP1

MicroRNAs have a role in the acquisition of stem cell-like properties of cancer cells. Here the authors show that microRNA-27b mediates generation of a side-population of breast cancer stem cells, in part by regulating the protein ENPP1, which has been previously linked to the development of diabetes.

Ryou-u Takahashi
Hiroaki Miyazaki
Takahiro Ochiya
ResearchOpen Access12 Jun 2015
Nature Communications

Volume: 6, P: 1-15
Catalytic Electroreduction of Dioxygen and Hydrogen Peroxide on Graphite Electrode Modified by Iron Phthalocyanine-Wrapping Poly(peptide)

Kenji Hanabusa
Xuanjing Ye
Hirofusa Shirai
Research01 May 1992
Polymer Journal

Volume: 24, P: 485-489
Poly(1-alkyne)s as a Comb-Like Polymer with a Rigid Main-Chain

Kenji Yokota
Masao Ohtubo
Yoshihito Inai
Research01 Oct 1993
Polymer Journal

Volume: 25, P: 1079-1086
Macular atrophy at 5 years after photodynamic therapy for polypoidal choroidal vasculopathy

Kentaro Kawai
Manabu Miyata
Akitaka Tsujikawa
Research14 Apr 2022
Eye

Volume: 37, P: 1067-1072
Preoperative detection of KRAS mutated circulating tumor DNA is an independent risk factor for recurrence in colorectal cancer

Yuki Nakamura
Shozo Yokoyama
Hiroki Yamaue
ResearchOpen Access11 Jan 2021
Scientific Reports

Volume: 11, P: 1-8
Structured ionized winds shooting out from a quasar at relativistic speeds

Observations of a luminous quasar from the high-resolution spectrometer Resolve aboard XRISM revealed highly inhomogeneous wind structure outflowing from a supermassive black hole, which probably consists of up to a million clumps.

Marc Audard
Hisamitsu Awaki
Yerong Xu
Research14 May 2025
Nature

Volume: 641, P: 1132-1136
Gut insulin action protects from hepatocarcinogenesis in diabetic mice comorbid with nonalcoholic steatohepatitis

Diabetes is known to increase the risk of nonalcoholic steatohepatitis (NASH) and hepatocellular carcinoma (HCC). Here, the authors show in a mice model that insulin action in the gut may play a protective role in the development of NASH and HCC in diabetes.

Kotaro Soeda
Takayoshi Sasako
Kohjiro Ueki
ResearchOpen Access18 Oct 2023
Nature Communications

Volume: 14, P: 1-18
Cosmid clones from microdissected human chromosomal region 15q11–q13

Takaya Tohma
Toshiya Tamura
Norio Niikawa
Research01 Sept 1993
Japanese Journal of Human Genetics

Volume: 38, P: 267-275
BRAF V600E mutation is a potential therapeutic target for a small subset of synovial sarcoma

Sho Watanabe
Akihiko Shimomura
Akihiko Yoshida
Research01 Apr 2020
Modern Pathology

Volume: 33, P: 1660-1668
A risk score predicting new incidence of hypertension in Japan

Yuka Kadomatsu
Mineko Tsukamoto
Kenji Wakai
Research20 Aug 2019
Journal of Human Hypertension

Volume: 33, P: 748-755
Four-Year Outcome of Aflibercept for Neovascular Age-Related Macular Degeneration and polypoidal choroidal vasculopathy

Keiichi Nishikawa
Akio Oishi
Akitaka Tsujikawa
ResearchOpen Access06 Mar 2019
Scientific Reports

Volume: 9, P: 1-7
Combined effect of weight gain within normal weight range and parental hypertension on the prevalence of hypertension; from the J-MICC Study

Rieko Okada
Yuka Kadomatsu
Kenji Wakai
Research03 Sept 2019
Journal of Human Hypertension

Volume: 34, P: 125-131
Prognostic impact of ACTN4 gene copy number alteration in hormone receptor-positive, HER2-negative, node-negative invasive breast carcinoma

Teppei Sugano
Masayuki Yoshida
Tesshi Yamada
ResearchOpen Access08 Apr 2020
British Journal of Cancer

Volume: 122, P: 1811-1817
Usefulness of Denoising Process to Depict Myopic Choroidal Neovascularisation Using a Single Optical Coherence Tomography Angiography Image

Yuka Sawai
Manabu Miyata
Akitaka Tsujikawa
ResearchOpen Access10 Apr 2020
Scientific Reports

Volume: 10, P: 1-6
Association between diaphragm excursion and whole-body muscle mass in older adults: an observational study

Shuji Ouchi
Toru Yamada
Masayoshi Hashimoto
ResearchOpen Access03 Jul 2025
Scientific Reports

Volume: 15, P: 1-8
p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response

Liquid-liquid phase separation of p62/SQSTM1 has been previously described, although the significance in vivo remains unclear. Here the authors show p62 droplets contain ubiquitin, autophagy-related proteins and Keap1 to serve as platform of not only autophagosome formation but also Nrf2 activation.

Shun Kageyama
Sigurdur Runar Gudmundsson
Masaaki Komatsu
ResearchOpen Access04 Jan 2021
Nature Communications

Volume: 12, P: 1-16
Earth's youngest exposed granite and its tectonic implications: the 10–0.8 Ma Kurobegawa Granite

Hisatoshi Ito
Ryuji Yamada
Tomokazu Hokada
ResearchOpen Access19 Feb 2013
Scientific Reports

Volume: 3, P: 1-5
Evaluation of the heterogeneous tissue distribution of erlotinib in lung cancer using matrix-assisted laser desorption ionization mass spectrometry imaging

Yukari Tsubata
Mitsuhiro Hayashi
Akinobu Hamada
ResearchOpen Access03 Oct 2017
Scientific Reports

Volume: 7, P: 1-6
Geranylgeranylacetone selectively binds to the HSP70 of Helicobacter pylori and alters its coccoid morphology

Ewa Grave
Shin-ichi Yokota
Hideaki Itoh
ResearchOpen Access08 Sept 2015
Scientific Reports

Volume: 5, P: 1-11
Acute effect of ambient ozone on heart rate variability in healthy elderly subjects

Xiaofeng Jia
Xiaoming Song
Xinbiao Guo
Research27 Apr 2011
Journal of Exposure Science & Environmental Epidemiology

Volume: 21, P: 541-547

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