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Fast-charging black phosphorus electrodes are limited by slow multiphase redox reactions. Here, authors engineer P–N bonds in the phosphorus bulk to accelerate lithium insertion and boost performance. Pouch cells can hit 80% charge in 10 min, delivering 282 Wh/kg and lasting over 3,400 cycles.

Lithium dendrites are a major barrier to the use of high-energy lithium metal batteries. Now, a highly adhesive polymer electrolyte is designed to suppress lithium dendrites by confining lithium in a continuous nucleation state through strong interfacial binding interactions.

To ensure high-potential stability, electrolytes for high-voltage lithium batteries often rely on fluorinated solvents that are costly and environmentally harmful. Now it has been shown that blocking the dominant α-oxidation of fluorine-free carboxylate solvents yields high-potential stability, enabling >650 Wh kg⁻¹ batteries with non-fluorinated electrolytes.

Inorganic cesium lead iodide perovskites promise stable solar cells but are limited by slow conversion from a templating phase. Li et al. tuned crystal orientation using surface-bound lead-complexing groups to speed conversion and achieve efficient, durable devices.

Neogene lithium isotope records from the Tibetan Plateau suggest that silicate weathering in mountain ranges may not persistently contribute sufficient lithium into the ocean to regulate seawater lithium isotope evolution

While there has been extensive theoretical analysis of the 3D nodal flat-band topological semimetals, experimental realization has proved challenging. Here, Wang, Li, Zhao, Wen, and coauthors find a robust flat magnetoresistance in D0₃-Fe₃Ga, which, combined with DFT calculations and Hall measurements, provide strong evidence that D0₃-Fe₃Ga is a 3D nodal flat-band ferromagnet.

The authors revealed that defective sulfation of a cholesterol-derived metabolite drives harmful lipid buildup in cartilage cells, while the sulfated form protects against osteoarthritis.

Regulatory T (Treg) cells influence adipose tissue homeostasis and hence metabolic health but the mechanisms are less well known. Here the authors establish, via gain and loss of function mouse models, that GPSM1expression in Treg cells regulate their expansion in adipose tissue, and upon genomic deletion of GSPM1, a specific subset of Treg cells expand and mitigate adipose tissue inflammation caused by high fat diet.

Soft robotics are promising to maneuver through complex environments, though it is challenging to design adaptable devices. Here the authors use a liquid crystal elastomer-based system to design a tunneling robot which can disrupt clogs in a model vascular system.

Macrophages and lipid metabolism have an important function in atherosclerosis. Here, the authors characterise the function of chitinase-like protein 3 (CHIL3) or its human functional homologue chitinase-3-like 2 (CHI3L2), and show these proteins enhance atherogenesis in a macrophage dependent manner and function by hydrolysing glycans on CD36 which enhances lipid uptake, activates mTOR and inflammatory macrophage responses and suppresses PPARγ-ABCG1-mediated cholesterol efflux.

As children enter adolescence, thinking becomes more abstract, coinciding with large-scale changes in brain network organization. Here, the authors show that stable brain network organization plays a more critical role than dynamic changes in shaping cognitive outcomes.

Dysregulated CD59 drives uncontrolled complement activation in neuromyelitis optica spectrum disorders (NMOSD). Here, the authors show in a mouse NMOSD model that endothelial SPARC suppresses astrocytic CD59 by blocking the VEGFA/VEGFR2 axis, promoting astrocytopathy, that might offer a potential therapeutic strategy.

Fibroblast heterogeneity is a hallmark of fibrosis including in the kidney, but their precise roles in driving renal fibrosis are incompletely understood. Here the authors report that a switch to a CD248⁺ extra cellular matrix -producing fibroblast subset contributes to kidney fibrosis, and blocking CD248 with a monoclonal antibody mitigates the phenotype in male mice.

The high demand of soft strain sensors requires solutions to reduce resource waste. Here, the authors propose a machine learning framework that corrects unstable signals in soft strain sensors, making them more accurate, reliable and longer-lasting, and extending their usable lifetime by more than 3,000 times.

Conversion-type batteries involving solid–solid transformations can store more energy than intercalation materials; however, their rates and cyclability have been limited by kinetics and incomplete conversion. This study introduces homonuclear dual-atom catalysts that increase the conductivity of insulating solid intermediates to enhance lithium–sulfur (and lithium–air) battery performance.

Fu and colleagues present LUNAR, a self-supervised neural-physics method that reconstructs 3D molecular positions and optical aberrations directly from raw microscopy data, enabling calibration-free super-resolution imaging in complex biological samples.

Electrosynthesis of 1,3-butadiene from dilute coal-derived acetylene is promising yet remains challenging due to competing side reactions. Here, the authors develop coordination-modulated dicopper molecular catalysts to steer the electrocatalytic dilute acetylene toward 1,3-butadiene.

Self-assembled monolayers struggle to uniformly coat textured surfaces, limiting high-efficiency perovskite and silicon tandem solar cells. Du et al. increase surface hydroxyl groups by incorporating carbon into polysilicon, enabling stable monolayer attachment and record device efficiency.

The authors report a resonant inelastic x-ray scattering study of superconducting Sm-based infinite-layer nickelate thin films. Despite the two-fold enhancement of T_c in the Sm-based nickelates compared to their Pr-based counterparts, they find that the effective in-plane exchange coupling strength is reduced by approximately 20%.

Analyzing spatial patterns and regulatory mechanisms in spatial multi-omics data remains challenging. Here, the authors present SpatialCOC, a deep learning framework that deciphers cellular spatial organization and cross-omics relationship.

Bright squeezed vacuum light boosts nonlinear atomic tunnelling ionization more than 20-fold compared with coherent light, enabling quantum control of strong-field processes without increasing classical intensity.

Guan et al. report a molecular regulator to control crystallization kinetics in Sn-based perovskite, resulting in elongated island-like grain structure that regulates charge injection and recombination, enabling NIR-II LEDs with efficiency of 10.7%, peak radiance of 173 W sr-1 m-2, and operational lifetime of 1,378 min.

Replicating the human brain’s imaginative ability has long been a core AI goal, yet current systems remain limited in speed and efficiency. Yang et al. present a hardware platform based on resistive memory, enabling high-speed, low-power AI content generation while fully preserving output quality.

Ni-decorated LiBH₄ nanocomposites achieve room-temperature hydrogenation of boron, enabled by synergistic catalysis and nanostructuring that promotes H₂ dissociation and B–H bond formation, a key step for practical hydrogen storage systems.

Ningxia was located at a crossroads between the Eurasian Steppe and East Asia. Here, the authors sequence 89 ancient individuals to reconstructs 4,000 years of genetic history in this region.

Global analysis of obesity trends from 1980 to 2024 in 200 countries and territories using data from 4,050 population-based studies reveals that framing obesity as a single global epidemic masks the highly varied dynamics across countries and age groups.

The authors introduce HyperRAG, a hypergraph-based retrieval method that captures higher-order relationships in domain knowledge to reduce hallucinations in large language models, improving accuracy and robustness across multiple datasets and medical tasks.

Human coronavirus HCoV-OC43, a prevalent cause of the common cold, shows differences between clinical isolates and tissue culture-adapted strains, raising concerns about the latter’s validity as a model. Here, the authors find that clinical isolates possess unique spike protein features affecting carbohydrate-binding properties, suggesting shared adaptation mechanisms with HCoV-HKU1 to the human sialoglycome.

Organic solar cells need acceptor molecules with long exciton diffusion lengths, but most available materials fail in thick films. The authors design new fluorinated quinoxaline acceptors that significantly improve carrier mobilities resulting in superior efficiency in both binary and ternary devices.

Si anodes could be an alternative to Li anodes in the application of solid-state batteries, but they suffer from issues such as severe volume expansion and sluggish kinetics. Here the researchers develop a Li–Si alloy anode that is stabilized by hard carbon, which leads to exceptional high-performance solid-state batteries.

Direct ethylene epoxidation with water is green but limited by poor ethylene capture and unstable intermediates. Here, the authors report a strained CuO–Ag heterojunction that enhances ethylene adsorption and stabilizes oxygen species via charge oscillations, enabling efficient epoxidation.

This study examines severe lattice distortions in concentrated solid solutions, enabling an energy landscape that immobilizes vacancies and interstitials which curbs their harmful evolution under irradiation conditions.

This study highlights a strategy to additively manufacture lightweight, strong, and ductile heat-resistant aluminum alloys. The partial solid-state amorphization of the nanoprecipitates during high-temperature tension offers an additional toughening mechanism.

In this study, the authors find that the perirhinal cortex controls hippocampal seizures in male mice via multiple downstream circuits that arise from distinct neuronal subpopulations, including projections to the fasciola cinerea, highlighting it as a promising therapeutic target.

Using time-resolved cryo-EM, this study captures fibrillar collagen assembly as it matures from a metastable to a stable state, shedding light on tissue maintenance and disease-linked defects.

The authors introduce controlled compositional heterogeneity to broaden polarization vector distributions while preserving the antiferroelectric modulation in PbZrO₃-based ceramics. They reduce polarization hysteresis while maintaining high polarization strength.

The dynamics at solid-gas interfaces at the atomic level remain a challenge due to transient processes and complex interfacial conditions. Here, the authors directly visualize reactions at the solid-gas interface and demonstrate a double-layer reconstruction that controls the nucleation and vertical growth of WS₂ on WO_2.72 nanowires.

Here they assemble a cross-species single-cell transcriptomic atlas of mammalian placentas and show that trophoblast diversification underlies placental evolution, while identifying TGIF1 as a regulator associated with preeclampsia and pregnancy loss.

Gene functional shifts can rewire molecular networks beyond expression changes. Here, authors present scDNS, which quantifies network divergence to infer gene perturbations and projects them to single cells, enabling sensitive detection of hidden regulation and heterogeneous responder states.

Lithium metal offers high specific capacity but suffers from dendrite growth and poor cycling stability. Here, authors develop a 3D Li-Zn-Li3N/CNT composite combining ductile Li-Zn alloy and a mechanically robust Li3N-CNTs network, enabling thin, durable electrodes with uniform lithium deposition, demonstrating a pouch-cell with a specific energy of 553 Wh kg-1.

Low-bandgap tin–lead perovskites can boost solar cell efficiency but degrade quickly due to tin oxidation. Here the authors add proton-scavenging additives that stabilize inks for over 300 days, enabling 24.06% single cells and 29.56% certified tandem efficiency.

Here, the authors uncover a mechanism by which drug-target homologs mediate non-antibiotic drug effects on bacterial growth, and suggest a universal homology-based competition strategy to reverse MTX-induced microbiota dysbiosis.

The authors conducted two trials to evaluate the efficacy and safety of NH600001, an etomidate derivative, in gastrointestinal endoscopy. The results showed NH600001 has a sedative effect while reducing the risk of adrenocortical depression.

Osteoporotic fractures often heal poorly due to high oxidative stress. Here, the authors develop an intelligent responsive hydrogel coating for magnesium implants that decelerates implant degradation, alleviates oxidative stress, and promotes bone regeneration.

Electrochemical conversion of propylene to propylene oxide using seawater is attractive but limited by inefficient use of reactive chlorine species. Here, the authors incorporate lithium into a cobalt catalyst to enhance radical generation, achieving industrial-level yields and high efficiency

The authors engineer an octahedrally rigid perovskite dielectric with a dual-cubic framework and cold-sintering-enabled microstructure, enabling stable capacitive energy storage up to 270 °C.

Neuraminidase activity of NEU1 regulates insulin resistance and glucose tolerance. Here the authors report that NEU1 also inhibits hepatic gluconeogenesis in a non-enzymatic manner by binding SAM68, thereby activating GCN5 transcription.