Nature Search

Acquisition of ampliconic sequences marks a selfish mouse t-haplotype

Mendelian genetics posits equal transmission of alleles, but selfish alleles can bias the transmission of large genomic regions or entire chromosomes. This study reveals the evolution of large amplicons as a distinct genetic feature of chromosomes with selfish alleles.

Callie M. Swanepoel
Gaojianyong Wang
Jacob L. Mueller
ResearchOpen Access01 Dec 2025
Nature Communications

Volume: 17, P: 1-13
Functional synapses between neurons and small cell lung cancer

Small cell lung cancer cells form functional synapses with glutamatergic neurons, receiving synaptic transmissions and deriving a proliferative advantage from these interactions.

Vignesh Sakthivelu
Anna Schmitt
Filippo Beleggia
ResearchOpen Access10 Sept 2025
Nature

Volume: 646, P: 1243-1253
Network-based analysis of differential white matter connectivity in major depressive disorder with and without comorbid anxiety

Marius Gruber
Jan Schulte
Jonathan Repple
ResearchOpen Access12 Jan 2026
Neuropsychopharmacology

P: 1-10
Gray matter correlates of childhood maltreatment lack replicability in a multi-cohort brain-wide association study

Surprisingly consistent replication failure of gray matter correlates of childhood maltreatment raises questions about publication bias in prior literature and about prevailing models linking maltreatment to brain structure in adult populations.

Janik Goltermann
Nils R. Winter
Udo Dannlowski
ResearchOpen Access16 Sept 2025
Nature Communications

Volume: 16, P: 1-14
Publisher Correction: Functional synapses between neurons and small cell lung cancer

Vignesh Sakthivelu
Anna Schmitt
Filippo Beleggia
Amendments and CorrectionsOpen Access19 Sept 2025
Nature

Volume: 646, P: E17
Potassium-selective single channels in guard cell protoplasts of Vicia faba

J. I. Schroeder
R. Hedrich
J. M. Fernandez
Research22 Nov 1984
Nature

Volume: 312, P: 361-362
Periodate-induced increase in cyclic GMP in mouse and guinea pig splenic cells in association with mitogenesis

M. K. HADDOX
L. T. FURCHT
N. D. GOLDBERG
Research01 Jul 1976
Nature

Volume: 262, P: 146-148
Structural brain abnormalities and aggression in schizophrenia: mega-analysis of data from 2095 patients and 2861 healthy controls via the ENIGMA consortium

Jelle Lamsma
Adrian Raine
Thomas Nickl-Jockschat
Research03 Dec 2025
Molecular Psychiatry

P: 1-10
Neurostructural subgroup in 4291 individuals with schizophrenia identified using the subtype and stage inference algorithm

Machine learning can be used to identify subtypes of psychiatric disease. Here the authors identified two neurostructural subgroups in schizophrenia, each showing reproducibility and generalizability across different collection locations and illness stages, using the SuStain algorithm.

Yuchao Jiang
Cheng Luo
Jianfeng Feng
ResearchOpen Access17 Jul 2024
Nature Communications

Volume: 15, P: 1-15
Evolution analysis of heterogeneous non-small cell lung carcinoma by ultra-deep sequencing of the mitochondrial genome

Wafa Amer
Csaba Toth
Margarete Odenthal
ResearchOpen Access11 Sept 2017
Scientific Reports

Volume: 7, P: 1-9
Regional brain morphology and current antidepressant use: findings from 32 international cohorts from the ENIGMA major depressive disorder working group

Chaira Serrarens
Yara J. Toenders
Laura S. van Velzen
ResearchOpen Access03 Nov 2025
Molecular Psychiatry

Volume: 30, P: 5625-5636
Transdiagnostic alterations in white matter microstructure associated with suicidal thoughts and behaviours in the ENIGMA Suicidal Thoughts and Behaviours consortium

Laura S. van Velzen
Lejla Colic
Lianne Schmaal
ResearchOpen Access24 Oct 2025
Translational Psychiatry

Volume: 15, P: 1-11
Formation and maintenance of Alzheimer's disease β-amyloid plaques in the absence of microglia

Contrary to previous findings, this study finds that ablation of microglia, the resident macrophages of the brain, does not affect amyloid plaque or neuritic pathology in two mouse models of Alzheimer's disease.

Stefan A Grathwohl
Roland E Kälin
Mathias Jucker
Research18 Oct 2009
Nature Neuroscience

Volume: 12, P: 1361-1363
Experimental evidence for temporal uncoupling of brain Aβ deposition and neurodegenerative sequelae

The poor correlation between brain Aβ deposition and clinical symptoms in Alzheimer´s disease remains puzzling. Here, the authors show a temporal dissociation of Aβ deposition and neurodegeneration.

Christine Rother
Ruth E. Uhlmann
Mathias Jucker
ResearchOpen Access28 Nov 2022
Nature Communications

Volume: 13, P: 1-11
Acute targeting of pre-amyloid seeds in transgenic mice reduces Alzheimer-like pathology later in life

Uhlmann et al. show that the preclinical phase of Alzheimer’s disease may in fact be a relatively late manifestation of a much earlier pathogenic and targetable process of seed formation and propagation.

Ruth E. Uhlmann
Christine Rother
Mathias Jucker
Research16 Nov 2020
Nature Neuroscience

Volume: 23, P: 1580-1588
Medin co-aggregates with vascular amyloid-β in Alzheimer’s disease

Medin promotes the formation of vascular aggregates with amyloid-β in mouse models and in human patients with Alzheimer’s disease, and is associated with vascular defects and cognitive decline.

Jessica Wagner
Karoline Degenhardt
Jonas J. Neher
ResearchOpen Access16 Nov 2022
Nature

Volume: 612, P: 123-131
Differential impact of manic versus depressive episode recurrence on longitudinal gray matter volume changes in bipolar disorder

Florian Thomas-Odenthal
Lea Teutenberg
Tilo Kircher
ResearchOpen Access15 Aug 2025
Neuropsychopharmacology

Volume: 51, P: 703-711
Association between polygenic risk for Major Depression and brain structure in a mega-analysis of 50,975 participants across 11 studies

Xueyi Shen
Yara J. Toenders
Greig de Zubicaray
ResearchOpen Access19 Aug 2025
Molecular Psychiatry

Volume: 31, P: 611-621
AKR1C3 enhances radioresistance in esophageal adenocarcinoma via inhibiting ferroptosis through suppressing TRIM21-mediated ubiquitination of HSPA5

Feng Ju
Jialei Weng
Yue Zhao
ResearchOpen Access02 Jul 2025
Cell Death & Disease

Volume: 16, P: 1-16
Predictive genetic markers in neoadjuvant chemoradiotherapy for locally advanced esophageal cancer: a long way to go. Review of the literature

M Gusella
E Pezzolo
F Pasini
Reviews13 Jun 2017
The Pharmacogenomics Journal

Volume: 18, P: 14-22
TAT-CRE inhalation enables tumor induction corresponding to adenoviral Cre-recombinase in a lung cancer mouse model

A comparison of lung adenocarcinomas induced by TAT-CRE or adenoviral Cre-recombinase revealed similar tumor growth with differences in micro-vessels and macrophages. TAT-CRE offers a valuable S1 alternative for cancer induction in mouse models

Tabea Gewalt
Anna M. Dmitrieva
Lydia Meder
ResearchOpen Access13 May 2025
Communications Biology

Volume: 8, P: 1-14
H19 and IGF-2 allele-specific expression in hepatoblastoma

J A Ross
G A Radloff
S M Davies
ResearchOpen Access20 Jan 2000
British Journal of Cancer

Volume: 82, P: 753-756
Reactivation of the maternally imprinted IGF2 allele in TGFα induced hepatocellular carcinomas in mice

Thomas M Harris
Leslie E Rogler
Charles E Rogler
Research23 Jan 1998
Oncogene

Volume: 16, P: 203-209
White matter microstructure in obesity and bipolar disorders: an ENIGMA bipolar disorder working group study in 2186 individuals

Lorielle M. F. Dietze
Sean R. McWhinney
Tamsyn E. Van Rheenen
Research05 Nov 2024
Molecular Psychiatry

Volume: 30, P: 1770-1779
Intraocular lens power calculation using ray tracing following excimer laser surgery

T M Rabsilber
A J Reuland
G U Auffarth
Research24 Feb 2006
Eye

Volume: 21, P: 697-701
Factor analysis of lifetime psychopathology and its brain morphometric and genetic correlates in a transdiagnostic sample

Axel Krug
Frederike Stein
Andreas J. Forstner
ResearchOpen Access03 Jun 2024
Translational Psychiatry

Volume: 14, P: 1-10
White and gray matter alterations in bipolar I and bipolar II disorder subtypes compared with healthy controls – exploring associations with disease course and polygenic risk

Katharina Thiel
Hannah Lemke
Udo Dannlowski
ResearchOpen Access08 Feb 2024
Neuropsychopharmacology

Volume: 49, P: 814-823
Neural foundation of the diathesis-stress model: longitudinal gray matter volume changes in response to stressful life events in major depressive disorder and healthy controls

Florian Thomas-Odenthal
Kai Ringwald
Tilo Kircher
ResearchOpen Access29 Mar 2024
Molecular Psychiatry

Volume: 29, P: 2724-2732
The interplay between polygenic score for tumor necrosis factor-α, brain structural connectivity, and processing speed in major depression

Kira Flinkenflügel
Marius Gruber
Udo Dannlowski
ResearchOpen Access01 May 2024
Molecular Psychiatry

Volume: 29, P: 3151-3159
Shared and distinct structural brain networks related to childhood maltreatment and social support: connectome-based predictive modeling

Alexandra Winter
Marius Gruber
Udo Dannlowski
ResearchOpen Access15 Sept 2023
Molecular Psychiatry

Volume: 28, P: 4613-4621
β-Adrenoceptor blockade in sclerosing cholangitis of Mdr2 knockout mice: antifibrotic effects in a model of nonsinusoidal fibrosis

Ingo Strack
Sigrid Schulte
Margarete Odenthal
Research04 Oct 2010
Laboratory Investigation

Volume: 91, P: 252-261
Longitudinal PET-MRI reveals β-amyloid deposition and rCBF dynamics and connects vascular amyloidosis to quantitative loss of perfusion

Longitudinal PET-MRI study on the dynamics of β-amyloid deposition and regional cerebral blood flow in the Alzheimer's disease mouse brain.

Florian C Maier
Hans F Wehrl
Bernd J Pichler
Research10 Nov 2014
Nature Medicine

Volume: 20, P: 1485-1492
Shear stress switches the association of endothelial enhancers from ETV/ETS to KLF transcription factor binding sites

Roman Tsaryk
Nora Yucel
Arndt F. Siekmann
ResearchOpen Access21 Mar 2022
Scientific Reports

Volume: 12, P: 1-15
Insulin-like growth factor-binding protein-3 inhibition of prostate cancer growth involves suppression of angiogenesis

B Liu
K-W Lee
P Cohen
Research18 Sept 2006
Oncogene

Volume: 26, P: 1811-1819
Bridging big data in the ENIGMA consortium to combine non-equivalent cognitive measures

Eamonn Kennedy
Shashank Vadlamani
Giovana B. Zunta-Soares
ResearchOpen Access16 Oct 2024
Scientific Reports

Volume: 14, P: 1-15
Diet and depression: future needs to unlock the potential

Wolfgang Marx
Melissa M. Lane
Felice N. Jacka
Correspondence09 Nov 2021
Molecular Psychiatry

Volume: 27, P: 778-780
Expression of platelet-derived growth factor-C and insulin-like growth factor I in hepatic stellate cells is inhibited by miR-29

Monika Kwiecinski
Natalia Elfimova
Margarete Odenthal
Research07 May 2012
Laboratory Investigation

Volume: 92, P: 978-987
Distinguishing chronic low back pain in young adults with mild to moderate pain and disability using trunk compliance

Alexander Stamenkovic
Brian C. Clark
James S. Thomas
ResearchOpen Access07 Apr 2021
Scientific Reports

Volume: 11, P: 1-10
Engineering adeno-associated virus 2 vectors for targeted gene delivery to atherosclerotic lesions

K White
H Büning
A H Baker
Research15 Nov 2007
Gene Therapy

Volume: 15, P: 443-451
Identification of serum angiopoietin-2 as a biomarker for clinical outcome of colorectal cancer patients treated with bevacizumab-containing therapy

V Goede
O Coutelle
U T Hacker
ResearchOpen Access05 Oct 2010
British Journal of Cancer

Volume: 103, P: 1407-1414
There is not much to mediate [yet] when it comes to diet and depression

M. L. Molendijk
P. Molero
W. van der Does
Correspondence09 Nov 2021
Molecular Psychiatry

Volume: 27, P: 776-777
Hox-C9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastoma

H Kocak
S Ackermann
M Fischer
ResearchOpen Access11 Apr 2013
Cell Death & Disease

Volume: 4, P: e586
Perp is required for tissue-specific cell survival during zebrafish development

M Nowak
C Köster
M Hammerschmidt
Research05 Nov 2004
Cell Death & Differentiation

Volume: 12, P: 52-64

Search

Filter By:

Search

Quick links