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Showing 1–50 of 103 results

Advanced filters: Author: Massimo Rossi Clear advanced filters

Olive fruit volatiles route intraspecific interactions and chemotaxis in Bactrocera oleae (Rossi) (Diptera: Tephritidae) females

Giulia Giunti
Orlando Campolo
Vincenzo Palmeri
ResearchOpen Access03 Feb 2020
Scientific Reports

Volume: 10, P: 1-10
Latent transition analysis for longitudinal studies of post-acute infection syndromes

Post-acute infection syndromes often have heterogeneous symptoms that are difficult to interpret. Here, the authors develop a latent trajectory analysis framework designed to categorise complex relationships in longitudinal data into distinct disease phenotypes and analyse transitions between them.

Roy Gusinow
Anna Górska
Clemens Peiter
ResearchOpen Access10 Feb 2026
Nature Communications

Volume: 17, P: 1-15
Computational enzyme design by catalytic motif scaffolding

A hybrid machine learning and atomistic modelling strategy enables one-shot design of efficient enzymes to catalyse diverse biological and non-biological chemical transformations.

Markus Braun
Adrian Tripp
Gustav Oberdorfer
ResearchOpen Access03 Dec 2025
Nature

Volume: 649, P: 237-245
Altered abundance in cancer patients gut of diadenylate cyclase-encoding bacteria

Francesco Candeliere
Laura Sola
Maddalena Rossi
ResearchOpen Access23 Jan 2026
Scientific Reports

Volume: 16, P: 1-9
Epigenetic dysregulation in aged muscle stem cells drives mesenchymal progenitor expansion via IL-6 and Spp1 signaling

Riparini et al. demonstrate that aged muscle stem cells amplify fibrosis by expanding mesenchymal progenitors via IL-6 and Spp1. Blocking these signals in aged mice curbs fibrosis and enhances muscle repair.

Giulia Riparini
Morgan Mackenzie
Vittorio Sartorelli
ResearchOpen Access29 Oct 2025
Nature Aging

Volume: 5, P: 2399-2416
Non-invasive stroke volume assessment during cardiopulmonary exercise testing provides additional insight beyond O₂-pulse in hypertrophic cardiomyopathy

Massimo Mapelli
Nikita Baracchini
Piergiuseppe Agostoni
ResearchOpen Access17 Feb 2026
Scientific Reports

Volume: 16, P: 1-11
Fast X-ray transient EP240315A from a Lyman-continuum-leaking galaxy at z ≈ 5

Observations of a fast X-ray transient reveal that it is a gamma-ray-burst explosion from a very distant galaxy that emits light with the wavelength necessary to drive cosmic reionization, the last major phase change in the history of the Universe.

Andrew J. Levan
Peter G. Jonker
Tayyaba Zafar
Research19 Aug 2025
Nature Astronomy

Volume: 9, P: 1375-1386
Type I IFNs promote cancer cell stemness by triggering the epigenetic regulator KDM1B

Type I interferons have been described to have protumor or antitumor functions depending on context. Here the authors show a protumor function for type I interferons in that they promote cancer stem cells by upregulating the chromatin remodeling factor KDM1B.

Martina Musella
Andrea Guarracino
Antonella Sistigu
ResearchOpen Access24 Aug 2022
Nature Immunology

Volume: 23, P: 1379-1392
Identification and mapping of human cDNAs homologous to Drosophila mutant genes through EST database searching

Sandro Banfi
Giuseppe Borsani
Andrea Ballabio
Research01 Jun 1996
Nature Genetics

Volume: 13, P: 167-174
Correction: Real-world multicenter analysis of CPX-351 efficacy in patients aged less than 60 years with secondary acute myeloid leukemia

Calogero Vetro
Bruno Garibaldi
Fabio Guolo
Amendments and CorrectionsOpen Access04 Dec 2025
Blood Cancer Journal

Volume: 15, P: 1
Author Correction: Type I IFNs promote cancer cell stemness by triggering the epigenetic regulator KDM1B

Martina Musella
Andrea Guarracino
Antonella Sistigu
Amendments and CorrectionsOpen Access17 Sept 2024
Nature Immunology

Volume: 25, P: 2166
A novel methodology for large-scale phylogeny partition

Phylogenetic analysis is used to identify transmission chains, but no software is available for the automated partition of large phylogenies. Prosperiet al. apply a new search algorithm to identify transmission clusters within the phylogeny of HIV-1gene sequences linking molecular and epidemiological data.

Mattia C.F. Prosperi
Massimo Ciccozzi
Andrea De Luca
Research24 May 2011
Nature Communications

Volume: 2, P: 1-10
Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis

Michael Seldin and colleagues report a genome-wide association study and meta-analyses for primary biliary cirrhosis. They identify three loci newly associated with susceptibility to this autoimmune liver disease.

Xiangdong Liu
Pietro Invernizzi
Michael F Seldin
Research18 Jul 2010
Nature Genetics

Volume: 42, P: 658-660
Quality of life in low-risk prostate cancer under active surveillance or following radical treatments: the START cohort study

Rosalba Rosato
Stefano De Luca
Andrea Di Stasio
ResearchOpen Access16 Oct 2025
Prostate Cancer and Prostatic Diseases

Volume: 29, P: 189-197
The geology and evolution of the Near-Earth binary asteroid system (65803) Didymos

Images collected during NASA’s DART mission of the asteroid Didymos and its moon, Dimorphos, are used to explore the origin and evolution of the binary system. Authors analysis indicate that both asteroids are weak rubble piles and that Didymos’ surface should be about 40 to 130 times older than Dimorphos.

Olivier Barnouin
Ronald-Louis Ballouz
Andrew S. Rivkin
ResearchOpen Access30 Jul 2024
Nature Communications

Volume: 15, P: 1-14
Measurement of Immunoglobulin Intraclonal diversification refines the clinical impact of IGHV mutational status in chronic lymphocytic leukemia

Filippo Vit
Tamara Bittolo
Riccardo Bomben
ResearchOpen Access18 Jun 2025
Leukemia

Volume: 39, P: 1905-1914
Elliptical ejecta of asteroid Dimorphos is due to its surface curvature

Double Asteroid Redirection Test (DART) mission impact on asteroid Dimophos resulted in an elliptical ejecta plume. Here, the authors show that this elliptical ejecta is due to the curvature of the asteroid and makes kinetic momentum transfer less efficient.

Masatoshi Hirabayashi
Sabina D. Raducan
Timothy J. Stubbs
ResearchOpen Access14 Feb 2025
Nature Communications

Volume: 16, P: 1-16
Acute and long-term disruption of glycometabolic control after SARS-CoV-2 infection

Fiorina and colleagues document alterations in glucose metabolism in patients with COVID-19 and use continuous glucose monitoring to show that glycaemic abnormalities could still be detected 2 months after disease onset in patients who had recovered.

Laura Montefusco
Moufida Ben Nasr
Paolo Fiorina
Research25 May 2021
Nature Metabolism

Volume: 3, P: 774-785
The p63 C-terminus is essential for murine oocyte integrity

The transcription factor p63 mediates different cellular responses affecting epithelial and oocyte biology. Here, the authors generate a mouse model (HET Δ13p63 mice) expressing the p63β isoform and show this affects ovary development, phenocopying a human syndrome, primary ovary insufficiency.

Anna Maria Lena
Valerio Rossi
Eleonora Candi
ResearchOpen Access15 Jan 2021
Nature Communications

Volume: 12, P: 1-14
Murine interferon-α₁ gene-transduced ESb tumor cells are rejected by host-mediated mechanisms despite resistance of the parental tumor to interferon-α/β therapy

Carmela Rozera
Monica Mecchia
Maria Ferrantini
Research01 Jun 1999
Cancer Gene Therapy

Volume: 6, P: 246-253
Rare and common genetic determinants of metabolic individuality and their effects on human health

Analyses of the genetic architecture of the human plasma metabolome in two large population-based cohorts identify associations between genetically determined metabolite levels and health.

Praveen Surendran
Isobel D. Stewart
Claudia Langenberg
ResearchOpen Access10 Nov 2022
Nature Medicine

Volume: 28, P: 2321-2332
Momentum transfer from the DART mission kinetic impact on asteroid Dimorphos

The authors report on a determination of the momentum transferred to an asteroid by kinetic impact, showing that the DART kinetic impact was highly effective in deflecting the asteroid Dimorphos.

Andrew F. Cheng
Harrison F. Agrusa
Giovanni Zanotti
ResearchOpen Access01 Mar 2023
Nature

Volume: 616, P: 457-460
Nilotinib versus imatinib with early switch from imatinib to nilotinib to obtain treatment-free remission in newly diagnosed chronic myeloid leukemia patients: the analysis of the first co-primary endpoint

Fausto Castagnetti
Massimo Breccia
Fabrizio Pane
ResearchOpen Access18 Nov 2025
Leukemia

Volume: 40, P: 47-54
Author Correction: The geology and evolution of the Near-Earth binary asteroid system (65803) Didymos

Olivier Barnouin
Ronald-Louis Ballouz
Andrew S. Rivkin
Amendments and CorrectionsOpen Access15 Nov 2024
Nature Communications

Volume: 15, P: 1
Targeting p53 and histone methyltransferases restores exhausted CD8+ T cells in HCV infection

Here, the authors report that exhausted HCV-specific CD8+ T cells are marked by upregulation of p53 signaling already detectable in an early phase of chronic HCV infection and by a later development of a repressive chromatin state, and show that chemical targeting of these pathways improves CD8+ T cell metabolism and antiviral function.

Valeria Barili
Paola Fisicaro
Carlo Ferrari
ResearchOpen Access30 Jan 2020
Nature Communications

Volume: 11, P: 1-20
Downregulation of TLX induces TET3 expression and inhibits glioblastoma stem cell self-renewal and tumorigenesis

TLX is a nuclear receptor essential for neural stem cell self-renewal and recently involved in glioblastoma development. In this study, the authors show that inhibition of TLX expression, achieved using a dendrimer nanovector-delivered siRNAs or viral vector-delivered shRNAs, reduces glioblastoma stem cells self renewal and in vivotumour growth through activation of TET3.

Qi Cui
Su Yang
Yanhong Shi
ResearchOpen Access03 Feb 2016
Nature Communications

Volume: 7, P: 1-15
Prevention of obesity in toddlers (PROBIT): a randomised clinical trial of responsive feeding promotion from birth to 24 months

Anita Morandi
Mara Tommasi
Claudio Maffeis
Research03 Jul 2019
International Journal of Obesity

Volume: 43, P: 1961-1966
Statins and clinical outcomes in patients with advanced hepatocellular carcinoma treated with Atezolizumab plus Bevacizumab

Andrea Dalbeni
Filippo Cattazzo
Elisa Pellegrini
ResearchOpen Access23 Nov 2025
Scientific Reports

Volume: 15, P: 1-12
Real-world multicenter analysis of CPX-351 efficacy in patients aged less than 60 years with secondary acute myeloid leukemia

Calogero Vetro
Bruno Garibaldi
Fabio Guolo
CorrespondenceOpen Access26 Oct 2025
Blood Cancer Journal

Volume: 15, P: 1-4
Insulinoma—new insights into an old disease

Trends in the presentation and management of insulinoma observed at the Mayo Clinic over the past 20 years have been reviewed in a new study. The findings shed light on poorly known and new findings of insulinoma and enable critical appraisal of current guidelines for the diagnosis and management of this condition.

Maria Vittoria Davì
Massimo Falconi
News & Views01 Jun 2009
Nature Reviews Endocrinology

Volume: 5, P: 300-302
Oocyte DNA damage quality control requires consecutive interplay of CHK2 and CK1 to activate p63

p63 activation in response to DNA damage leads to oocyte death and loss of fertility in women receiving chemotherapy. Activation requires sequential phosphorylation by CHK2 and CK1 kinases, and inhibition of these kinases rescues oocytes from apoptosis induced by chemotherapy.

Marcel Tuppi
Sebastian Kehrloesser
Volker Dötsch
Research26 Feb 2018
Nature Structural & Molecular Biology

Volume: 25, P: 261-269
AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders

Genetic variants in ionotropic glutamate receptors have been implicated in neurodevelopmental disorders. Here, the authors report heterozygous de novo mutations in the GRIA2 gene in 28 individuals with intellectual disability and neurodevelopmental abnormalities associated with reduced Ca²⁺ transport and AMPAR currents.”

Vincenzo Salpietro
Christine L. Dixon
Henry Houlden
ResearchOpen Access12 Jul 2019
Nature Communications

Volume: 10, P: 1-16
International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways

Primary biliary cirrhosis is an autoimmune liver disease with poor therapeutic options. Here Cordell et al. a perform meta-analysis of European genome-wide association studies identifying six novel risk loci and a number of potential therapeutic pathways.

Heather J. Cordell
Younghun Han
Katherine A. Siminovitch
ResearchOpen Access22 Sept 2015
Nature Communications

Volume: 6, P: 1-11
Mutant p53 blocks SESN1/AMPK/PGC-1α/UCP2 axis increasing mitochondrial O_2ˉ· production in cancer cells

Marco Cordani
Giovanna Butera
Massimo Donadelli
ResearchOpen Access15 Oct 2018
British Journal of Cancer

Volume: 119, P: 994-1008
Validation of a biological score to predict response in chronic lymphocytic leukemia patients treated front-line with bendamustine and rituximab

Massimo Gentile
Tait D. Shanafelt
Fortunato Morabito
Research20 Mar 2018
Leukemia

Volume: 32, P: 1869-1873
Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia

Evolutionarily conserved gene modules mediate neurodegenerative dementia in a variety of mouse models and in postmortem brain tissue from patients.

Vivek Swarup
Flora I. Hinz
Daniel H. Geschwind
Research03 Dec 2018
Nature Medicine

Volume: 25, P: 152-164
Argo Delphi consensus statement on red flags and clinical gateways towards rare disease diagnosis

Giuseppe Limongelli
Fabio De Iaco
Roberta Veneziano
ResearchOpen Access11 Nov 2025
Scientific Reports

Volume: 15, P: 1-13
Transcriptome signatures from discordant sibling pairs reveal changes in peripheral blood immune cell composition in Autism Spectrum Disorder

Michele Filosi
Tony Kam-Thong
Enrico Domenici
ResearchOpen Access14 Apr 2020
Translational Psychiatry

Volume: 10, P: 1-12
Valvular heart disease and cardiomyopathy: reappraisal of their interplay

In this Review, Marsan et al. discuss the different clinical scenarios in which valvular heart diseases and cardiomyopathies coexist, either as the cause of one another or because of a common aetiology, to highlight the need for an improved classification of these diseases with potential repercussions in clinical management and personalized treatment.

Nina Ajmone Marsan
Francesca Graziani
Filippo Crea
Reviews10 Aug 2023
Nature Reviews Cardiology

Volume: 21, P: 37-50
Isolated Bone Marrow Manifestation of HIV-Associated Hodgkin Lymphoma

Maurilio Ponzoni
Luca Fumagalli
Fabio Facchetti
Research01 Dec 2002
Modern Pathology

Volume: 15, P: 1273-1278
The VLA-4 integrin is constitutively active in circulating chronic lymphocytic leukemia cells via BCR autonomous signaling: a novel anchor-independent mechanism exploiting soluble blood-borne ligands

Erika Tissino
Annalisa Gaglio
Valter Gattei
ResearchOpen Access14 Aug 2024
Leukemia

Volume: 38, P: 2127-2140
CPX-351 treatment in secondary acute myeloblastic leukemia is effective and improves the feasibility of allogeneic stem cell transplantation: results of the Italian compassionate use program

Fabio Guolo
Luana Fianchi
Roberto Massimo Lemoli
ResearchOpen Access06 Oct 2020
Blood Cancer Journal

Volume: 10, P: 1-11
Long term results of down-staging and liver transplantation for patients with hepatocellular carcinoma beyond the conventional criteria

Matteo Ravaioli
Federica Odaldi
Antonio Daniele Pinna
ResearchOpen Access07 Mar 2019
Scientific Reports

Volume: 9, P: 1-9
Winter snow deficit was a harbinger of summer 2022 socio-hydrologic drought in the Po Basin, Italy

Low snow water equivalent in the Italian Alps during the 2021–2022 winter was a key cause of the subsequent summer drought in the Po River Basin, according to an assessment which combines satellite and ground-based data with water restriction records.

Francesco Avanzi
Francesca Munerol
Luca Ferraris
ResearchOpen Access03 Feb 2024
Communications Earth & Environment

Volume: 5, P: 1-12
An enhanced rainfall-induced landslide catalogue in Italy

Maria Teresa Brunetti
Stefano Luigi Gariano
Silvia Peruccacci
ResearchOpen Access05 Feb 2025
Scientific Data

Volume: 12, P: 1-10
Richter transformation in diffuse large B-cell lymphoma in patients with chronic lymphocytic leukemia receiving ibrutinib: risk factors and outcomes

Sara Pepe
Candida Vitale
Francesca R. Mauro
ResearchOpen Access25 Jun 2025
Leukemia

Volume: 39, P: 1883-1891
Integration of [¹⁸F]FDG-PET radiomics with liquid biopsy improves outcome prediction in newly diagnosed diffuse large B-cell lymphoma

Riccardo Dondolin
Federico Garrou
Riccardo Moia
ResearchOpen Access08 Jul 2025
Leukemia

Volume: 39, P: 2207-2214
A machine-learning parsimonious multivariable predictive model of mortality risk in patients with Covid-19

Rita Murri
Jacopo Lenkowicz
Lorenzo Zileri Dal Verme
ResearchOpen Access27 Oct 2021
Scientific Reports

Volume: 11, P: 1-10
Clinical impact of TP53 disruption in chronic lymphocytic leukemia patients treated with ibrutinib: a campus CLL study

Riccardo Bomben
Francesca Maria Rossi
Valter Gattei
ResearchOpen Access18 Feb 2023
Leukemia

Volume: 37, P: 914-918
Impact of ELN clinical signs and symptoms on the thrombotic risk in polycythemia vera patients treated with front-line hydroxyurea

Francesca Palandri
Massimo Breccia
Valerio De Stefano
ResearchOpen Access28 May 2025
Leukemia

Volume: 39, P: 1928-1936

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