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Showing 1–50 of 82 results

Advanced filters: Author: Mingxia Li Clear advanced filters

Identification and characterization of MARCO-expressing tumor-associated macrophages in pancreatic ductal adenocarcinoma with pan-cancer relevance

Hao Sun
Mengya Gao
Linping Xu
ResearchOpen Access24 Jan 2026
npj Precision Oncology

P: 1-17
Novel insights into the protective role of crocetin from gardenia jasminoides against mitochondrial hypoxia

Li Boshen
Zhang Mingxia
Li Maoxing
ResearchOpen Access11 Dec 2025
Scientific Reports

Volume: 16, P: 1-16
Targeting sorting nexin 3 to treat pulmonary fibrosis by dual modulating Wnt/β-catenin signaling

Dinghu Ma
Wenjing Yu
Jing Lu
ResearchOpen Access15 Jan 2026
Cell Death & Disease

Volume: 17, P: 1-19
Telomere-to-telomere Citrullus super-pangenome provides direction for watermelon breeding

Citrullus super-pangenome constructed using 27 telomere-to-telomere assemblies encompassing all seven Citrullus species highlights genomic diversity across wild and cultivated watermelons and the potential for crop improvement.

Yilin Zhang
Mingxia Zhao
Hang He
ResearchOpen Access08 Jul 2024
Nature Genetics

Volume: 56, P: 1750-1761
The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK

A small-molecule aldolase inhibitor, aldolazin is reported and shown to selectively activate the lysosomal pool of AMPK, which has glucose-lowering effects in rodents.

Chen-Song Zhang
Mengqi Li
Sheng-Cai Lin
ResearchOpen Access10 Oct 2022
Nature Metabolism

Volume: 4, P: 1369-1401
Adipocyte CLDN5 promotes thermogenesis and energy expenditure through regulation of IL10 expression

Claudin proteins maintain epithelial and endothelial tight junctions, but their functions in adipocytes lacking such junctions remain unclear. Here, the authors show that claudin-5 present in non-thermogenic adipocytes regulates thermogenesis and energy expenditure by modulating IL-10 secretion.

Ke Feng
Wenqin Wang
Shengtian Zhao
ResearchOpen Access04 Jul 2025
Nature Communications

Volume: 16, P: 1-23
Self-supervised learning with application for infant cerebellum segmentation and analysis

Neuroimaging of the cerebellum in infants has been challenging. Here the authors describe a framework for cerebellum MRI segmentation in infants up to 2 years.

Yue Sun
Limei Wang
Li Wang
ResearchOpen Access05 Aug 2023
Nature Communications

Volume: 14, P: 1-12
Structure of Csx1-cOA₄ complex reveals the basis of RNA decay in Type III-B CRISPR-Cas

Type III CRISPR-Cas RNases from the Csm and Csx families are activated by cyclic oligoadenylates (cOA). Here the authors present the cOA bound Sulfolobus islandicus Csx1 structure, which forms a hexamer and reveal an allosteric mechanism for the activation of Csx1 RNase.

Rafael Molina
Stefano Stella
Guillermo Montoya
ResearchOpen Access20 Sept 2019
Nature Communications

Volume: 10, P: 1-14
HER2-targeting antibody drug conjugate FS-1502 in HER2-expressing metastatic breast cancer: a phase 1a/1b trial

Safety concerns limit the success of HER2-targeting antibody-drug conjugates (ADCs) for the treatment of HER2-postive breast cancer. Here, the authors present a phase 1a/b trial reporting the safety and preliminary efficacy of FS-1502, an anti-HER2 ADC with a cancer-selective cleavable linker, for the treatment of HER2-positive metastatic breast cancer.

Qiao Li
Ying Cheng
Binghe Xu
ResearchOpen Access17 Jun 2024
Nature Communications

Volume: 15, P: 1-10
Establishing altitude-based coagulation reference ranges in Western Sichuan

Qing Yuan
YanWu Liu
Zhenglin Huang
ResearchOpen Access07 May 2025
Scientific Reports

Volume: 15, P: 1-9
Longitudinal analysis of antibody dynamics in COVID-19 convalescents reveals neutralizing responses up to 16 months after infection

A longitudinal analysis of the neutralizing antibody response dynamics in 214 COVID-19 convalescents up to 16 months after infection shows that despite substantial declines in antibody levels over time, they could still provide protection against circulating variants even after one year of infection in most individuals, although neutralizing activities were reduced, particularly against Beta, Delta and Mu SARS-CoV-2 variants.

Yang Yang
Minghui Yang
Yingxia Liu
Research07 Feb 2022
Nature Microbiology

Volume: 7, P: 423-433
Loss of CLDN5 in podocytes deregulates WIF1 to activate WNT signaling and contributes to kidney disease

Claudin-5 is a tight junction integral membrane protein, but it is also expressed in mature podocytes which lack tight junctions. Here the authors report that podocyte claudin-5 regulates WNT signaling activity by modulating WIF1 expression, and its downregulation contributes to kidney disease progression in mice.

Hui Sun
Hui Li
Yongfeng Gong
ResearchOpen Access24 Mar 2022
Nature Communications

Volume: 13, P: 1-18
Association of hemoglobin with decreased prevalence of diabetic retinopathy among Tibetan male patients

Weijing Yin
Yan Ye
Chenghui Zhang
ResearchOpen Access17 Apr 2025
Scientific Reports

Volume: 15, P: 1-8
A proof of concept study of ¹⁸F-FDG PET/CT patient-level radiomics identify refractory/relapsed diffuse large B-cell lymphoma

Caozhe Cui
Jianbo Cao
Zhifang Wu
ResearchOpen Access30 Sept 2025
Scientific Reports

Volume: 15, P: 1-11
AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1

Shi et al. show that following adrenergic signalling, PKA phosphorylates AIDA, which in turn interacts with and promotes oxidation of UCP1 to regulate UCP1-dependent adaptive thermogenesis.

Meng Shi
Xiao-Yu Huang
Sheng-Cai Lin
Research04 Mar 2021
Nature Cell Biology

Volume: 23, P: 268-277
Molecular profiles and tumor mutational burden analysis in Chinese patients with gynecologic cancers

Min Wang
Wensheng Fan
Yuanguang Meng
ResearchOpen Access12 Jun 2018
Scientific Reports

Volume: 8, P: 1-9
Lithocholic acid phenocopies anti-ageing effects of calorie restriction

Lithocholic acid is one of the metabolites upregulated during calorie restriction, and treatment of mice, worms and flies with this bile acid alone can reproduce the health benefits of calorie restriction.

Qi Qu
Yan Chen
Sheng-Cai Lin
ResearchOpen Access18 Dec 2024
Nature

Volume: 643, P: 192-200
Low-dose metformin targets the lysosomal AMPK pathway through PEN2

The molecular target of the antidiabetic medicine metformin is identified as PEN2, a subunit of γ-secretases, and the PEN2–ATP6AP1 axis offers potential targets for screening for metformin substitutes.

Teng Ma
Xiao Tian
Sheng-Cai Lin
ResearchOpen Access23 Feb 2022
Nature

Volume: 603, P: 159-165
Phase 1b trial of anti-EGFR antibody JMT101 and Osimertinib in EGFR exon 20 insertion-positive non-small-cell lung cancer

Patients with non-small cell lung cancer (NSCLC) with EGFR exon 20 insertions are resistant to early generation EGFR tyrosine kinase inhibitors (TKI). Here, the authors report the safety and preliminary efficacy of a phase I clinical trial JMT101, an anti-EGFR antibody, combined with EGFR-TKI, afatinib or osimertinib, in patients with NSCLC.

Shen Zhao
Wu Zhuang
Wenfeng Fang
ResearchOpen Access12 Jun 2023
Nature Communications

Volume: 14, P: 1-16
Turing patterns with high-resolution formed without chemical reaction in thin-film solution of organic semiconductors

Regular patterns can form spontaneously in chemical reaction-diffusion systems under non-equilibrium conditions as proposed by Alan Turing. Here, the authors generate regular patterns in uphill-diffusion solution systems without a chemical reaction process through in-situ and ex-situ observations.

Zezhong Xiang
Jin Li
Shunpu Li
ResearchOpen Access02 Dec 2022
Nature Communications

Volume: 13, P: 1-9
The proto-oncogene tyrosine kinase c-SRC facilitates glioblastoma progression by remodeling fatty acid synthesis

Fatty acid synthesis has been reported to promote glioblastoma. Here, the authors show that the tyrosine kinase c-SRC phosphorylates both acetyl-CoA synthetase ACSS2 and ATP-citrate lyase ACLY, to increase acetyl-CoA and NADPH production for fatty acid synthesis to support glioblastoma progression.

Wentao Zhao
Cong Ouyang
Zhanxiang Wang
ResearchOpen Access28 Aug 2024
Nature Communications

Volume: 15, P: 1-18
The expression level of Neuronal Calcium Sensor 1 can predict the prognosis of cytogenetically normal AML

Weilong Zhang
Jing Wang
Hongmei Jing
Research14 Mar 2023
The Pharmacogenomics Journal

Volume: 23, P: 89-94
Circadian regulation of GABA_A receptor function by CKIε-CKIδ in the rat suprachiasmatic nuclei

Ke Ning
Lei Li
Qi Wan
Research18 Apr 2004
Nature Neuroscience

Volume: 7, P: 489-490
Disruption of PTEN coupling with 5-HT2C receptors suppresses behavioral responses induced by drugs of abuse

Shao-Ping Ji
Yun Zhang
Xia Zhang
Research12 Feb 2006
Nature Medicine

Volume: 12, P: 324-329
Preferred crystal plane electrodeposition of aluminum anode with high lattice-matching for long-life aluminum batteries

An aluminum anode is proposed to achieve high lattice matching between the aluminum anode and the aluminum deposit, allowing the aluminum deposits to maintain preferred crystal face growth on the aluminum anode surface.

Shixin Wang
Yuan Guo
Mingxia Liu
ResearchOpen Access01 Aug 2024
Nature Communications

Volume: 15, P: 1-11
Promoting potato as a substitute in low-yield regions for grain crops can achieve multiple benefits in China

Replacing staple grains with potatoes in China’s low-yield regions boosts yields by 2-119% and doubles economic returns while cutting greenhouse gas emissions and intensities, based on a hybrid approach integrating a process-based model with a life cycle assessment.

Yang Li
Jing Wang
Senthold Asseng
ResearchOpen Access21 Nov 2025
Communications Earth & Environment

Volume: 6, P: 1-12
Dynamic allometric scaling of tree biomass and size

Projecting biomass carbon in forests is challenging due to the modelling of different-sized trees. This Article proposes a dynamic allometric scaling relationship that better fits scaling patterns for large trees and their biomass.

Xiaolu Zhou
Mingxia Yang
Changhui Peng
Research04 Jan 2021
Nature Plants

Volume: 7, P: 42-49
Tuberculosis infection in rural labor migrants in Shenzhen, China: Emerging challenge to tuberculosis control during urbanization

Xiangwei Li
Qianting Yang
Lei Gao
ResearchOpen Access30 Jun 2017
Scientific Reports

Volume: 7, P: 1-8
Preparation of Aluminum Nanomesh Thin Films from an Anodic Aluminum Oxide Template as Transparent Conductive Electrodes

Yiwen Li
Yulong Chen
Rui Chen
ResearchOpen Access02 Feb 2016
Scientific Reports

Volume: 6, P: 1-7
Author Correction: Lithocholic acid phenocopies anti-ageing effects of calorie restriction

Qi Qu
Yan Chen
Sheng-Cai Lin
Amendments and CorrectionsOpen Access28 Jan 2025
Nature

Volume: 638, P: E6
Remodeling of active endothelial enhancers is associated with aberrant gene-regulatory networks in pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is a heterogeneous disease, causing severe breathing problems and cardiac morbidity. Here, the authors study chromatin marks in pulmonary arterial endothelial cells from PAH patients and controls and find changes in transcription factor and enhancer activity that suggest an aberrant response to signalling in PAH.

Armando Reyes-Palomares
Mingxia Gu
Judith B. Zaugg
ResearchOpen Access03 Apr 2020
Nature Communications

Volume: 11, P: 1-14
Taming interfacial electronic properties of platinum nanoparticles on vacancy-abundant boron nitride nanosheets for enhanced catalysis

Tuning electronic properties of metallic catalysts is a useful way to improve their activity, however control over metal-support interactions is still challenging. Here the authors report a vacancy-induced interfacial electronic effect for Pt assembled on vacancy-abundanth-BN nanosheets leading to superior CO oxidation catalysis.

Wenshuai Zhu
Zili Wu
Huiyuan Zhu
ResearchOpen Access09 Jun 2017
Nature Communications

Volume: 8, P: 1-7
Seasonal pattern of influenza activity in a subtropical city, China, 2010–2015

Xu-Xiang Liu
Yahong Li
Xi-Ling Wang
ResearchOpen Access13 Dec 2017
Scientific Reports

Volume: 7, P: 1-7
A Broadband THz-TDS System Based on DSTMS Emitter and LTG InGaAs/InAlAs Photoconductive Antenna Detector

Ying Zhang
Xiaoling Zhang
Weili Zhang
ResearchOpen Access31 May 2016
Scientific Reports

Volume: 6, P: 1-6
Determination of plane stress state using terahertz time-domain spectroscopy

Zhiyong Wang
Kai Kang
Weili Zhang
ResearchOpen Access08 Nov 2016
Scientific Reports

Volume: 6, P: 1-6
In situ synthesis, enhanced luminescence and application in dye sensitized solar cells of Y₂O₃/Y₂O₂S:Eu³⁺ nanocomposites by reduction of Y₂O₃:Eu³⁺

Guohai Yuan
Mingxia Li
Honggang Fu
ResearchOpen Access22 Nov 2016
Scientific Reports

Volume: 6, P: 1-9
Discriminating Active Tuberculosis from Latent Tuberculosis Infection by flow cytometric measurement of CD161-expressing T cells

Qianting Yang
Qian Xu
Xinchun Chen
ResearchOpen Access08 Dec 2015
Scientific Reports

Volume: 5, P: 1-8
DNA polymerase iota promotes EMT and metastasis of esophageal squamous cell carcinoma by interacting with USP7 to stabilize HIF-1α

Aidi Gao
Mingxia Zhang
Yuandong Cao
ResearchOpen Access24 Feb 2024
Cell Death & Disease

Volume: 15, P: 1-13
Gain of miR-151 on chromosome 8q24.3 facilitates tumour cell migration and spreading through downregulating RhoGDIA

Twenty-two microRNAs are found to be amplified or deleted in hepatocellular carcinoma (HCC). miR-151 is encoded by an intron in the focal adhesion kinase FAK-1 gene, with which it is co-transcribed, and increases HCC cell migration in vitro and invasion in vivo by directly targeting RhoGDIA. miR-151 amplification correlates with HCC metastasis.

Jie Ding
Shenglin Huang
Xianghuo He
Research21 Mar 2010
Nature Cell Biology

Volume: 12, P: 390-399
Cost-effectiveness of CDK4/6 inhibitors for second-line HR+/HER2− advanced or metastatic breast cancer in China

Caifeng Jia
Sen Zhang
Mingxia Wang
ResearchOpen Access14 Apr 2025
Scientific Reports

Volume: 15, P: 1-13
A Study of the White-Coat Phenomenon in Patients with Primary Hypertension

Ning Zhu
Minrui Bu
Xiaoli Zou
Research01 Jan 2008
Hypertension Research

Volume: 31, P: 37-41
The mediating effects of death reflection on death literacy and death anxiety among Chinese nurses: a cross-sectional study

Xiaoke Zhang
Huilin Zhang
Zuming Qin
ResearchOpen Access28 Dec 2024
Scientific Reports

Volume: 14, P: 1-8
Association between Non high density lipoprotein to high density lipoprotein cholesterol ratio and bone mineral density

Ying Zhou
Ning Su
Jie Chen
ResearchOpen Access17 Jul 2025
Scientific Reports

Volume: 15, P: 1-9
Author Correction: π-HuB: the proteomic navigator of the human body

Fuchu He
Ruedi Aebersold
Zemin Zhang
Amendments and Corrections23 Dec 2024
Nature

Volume: 637, P: E22
N⁶-methyladenosine modification of REG1α facilitates colorectal cancer progression via β-catenin/MYC/LDHA axis mediated glycolytic reprogramming

Mingxia Zhou
Jing He
Hongtao Wen
ResearchOpen Access25 Aug 2023
Cell Death & Disease

Volume: 14, P: 1-16
Deciphering the tumor-suppressive role of RBMS3 in lung adenocarcinoma through genomic insights into prognosis and mechanisms

Li Lv
Tengxiang Zhong
Jie Lin
ResearchOpen Access28 Mar 2025
Scientific Reports

Volume: 15, P: 1-20
SLC34A2 simultaneously promotes papillary thyroid carcinoma growth and invasion through distinct mechanisms

Jing He
Mingxia Zhou
Qiang Zou
Research31 Jan 2020
Oncogene

Volume: 39, P: 2658-2675
High-resolution multi-source traffic data in New Zealand

Bo Li
Ruotao Yu
Haiwang Zhong
ResearchOpen Access12 Nov 2024
Scientific Data

Volume: 11, P: 1-9
Clinical characteristics and unique presentations of immune checkpoint inhibitor induced type 1 diabetes in Chinese patients from a single institution

Wei Liu
Chunmei Li
Linong Ji
ResearchOpen Access13 Feb 2025
Scientific Reports

Volume: 15, P: 1-8
Variations and influencing factors of vegetation net primary productivity over 31 years in Wuyishan National Park, China

Mingxia Zhang
Naifeng Lin
Yun Zhang
ResearchOpen Access22 Nov 2024
Scientific Reports

Volume: 14, P: 1-19

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