Conventional histological and cytological stains, including hematoxylin & eosin and Papanicolaou, are combined with immunohistochemistry and simultaneously evaluated on the same specimen slide by use of invisible chromogens. Visible and invisible light used to illuminate the specimen are separated and directed to color and monochrome cameras, respectively, providing conventional stain and immunohistochemistry in side-by-side videos on the computer monitor. Alternatively, multispectral imaging of single microscope fields provides archiving and further evaluation utilizing image processing.
- Larry E. Morrison
- Mark R. Lefever
- Daniel R. Bauer
