The preparation and characterization of chitosan nanoparticles loaded with H5N1 antigen using the spray-drying technique is conducted. The obtained nanoparticles were characterized by SEM, TEM, and zeta potential analysis to evaluate morphology, size, and surface charge. The antigen-loaded chitosan nanoparticles were subsequently assessed for safety and immunological effects in a mouse model, demonstrating their potential as a vaccine delivery system.
- Anh Dzung Nguyen
- Yen Nhi Nguyen
- Bao Van Cao
