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Introducing viscoelasticity by addition of DNA into the fluid surrounding a suspension of Escherichia coli produces a giant oscillating vortex with a period controllable through the DNA concentration.

Isocitrate dehydrogenase 1/2 mutant (IDHmt) astrocytomas are characterized by a scarcity of T cells, but their phenotypes and functionality are lesser known. Here authors provide an integrative approach to describe the immune microenvironment of these tumors and show that gemistocytic tumor cells, a cell type abundant in the tumor stroma surrounding perivascular T cell accumulations, generate a glial scarring-like functional state, responsible for T cell exclusion.

Here the authors developed an open-source program (DRfold) for RNA tertiary structure prediction from sequence. Through a unique combination of end-to-end learning and geometry restraint guided simulations, the method demonstrates advantage over peer methods.

Thanks to their strong light-matter interaction, atomically thin transition metal dichalcogenides are ideal active materials for cavity quantum electrodynamics. Here, the authors embed a WSe₂monolayer within a Tamm-plasmon-polariton cavity, and observe exciton-polariton formation at room temperature.

Here, the authors report the observation of two solid-state analogues of well-known high-energy physics effects in graphene samples irradiated by infrared photons under non-equilibrium conditions. Depending on the carrier density of graphene, they observed asymmetric plasmon damping, and anomalous photocurrents associated with the condensed matter versions of the Cherenkov and Schwinger effects.

Correlated electronic states in moiré matter are of great fundamental and technological interest. Here, the authors demonstrate a Josephson junction in magic-angle twisted bilayer graphene with a correlated insulator weak link, showing magnetism and programmable superconducting diode behaviour.

Here, the authors report a near-field study of hyperbolic phonon polaritons in linear antennas made of hexagonal boron nitride. Infrared nanospectroscopy and nanoimaging experiments reveal sharp Fabry-Perot resonances with large quality factors, exhibiting atypical modal behaviour.

Dielectric nano-antennas may be used as a platform for boosting light-matter coupling in 2D semiconductors. Here, the authors demonstrate the coupling of atomically thin WSe\({}_{2}\) with low-loss, high-refractive-index GaP nano-antennas and observe a 10000-fold WSe\({}_{2}\) photoluminescence enhancement.

Two broadly reactive and inhibitory human monoclonal antibodies against the malaria parasite Plasmodium falciparum have been characterized, providing insights into immunity, prevention and treatment of severe malaria.

A very high-energy muon observed by the KM3NeT experiment in the Mediterranean Sea is evidence for the interaction of an exceptionally high-energy neutrino of cosmic origin.  

Momentum mismatch prevents efficient coupling between free space photons and hyperbolic phonon polaritons. The authors show, using far-field infrared spectroscopy, infrared nanoimaging and numerical simulations, that resonant metallic antennas can efficiently launch hyperbolic phonon polaritons in thin h-BN slabs.

The enhanced observability of bilaterally accessible gastrointestinal organoid-derived monolayers facilitates the study of parasite infection of the gut.

Here the authors uncovered CNOT3, a subunit of the CCR4-NOT complex, as an essential modulator of translation in leukemia. The work pointed to the potential of targeting the posttranscriptional circuitry via CNOT3 as a therapeutic vulnerability in acute myeloid leukemia.

Microbial communication has significant implications for industrial applications, but constructing communication systems which support coordinated behaviors is challenging. Here, the authors report an electron transfer triggered redox communication network and demonstrate its ability to coordinate microbial metabolism.

The magnetic state of twisted double bilayers of antiferromagnetic chromium triiodide can be controlled by electrical gating, twist angle and temperature.

Electroadhesion in soft robotics provides controllable interfacial attraction for robotic functionalities but materials selection is limited. Here, Gao et. al. present an iontronic adhesive to design a soft iontronic gripper with self-healability, tunable adhesion at reduced voltages and rapid release.

Fossil tooth development suggests an extended human growth phase occurred at least 1.77 million years ago, possibly reflecting a shift towards extended parenting and reproductive success, rather than increasing brain size.

Topologically protected hinge modes could be important for developing quantum devices, but electronic transport through those states has not been demonstrated. Now quantum transport has been shown in gapless topological hinge states.

The occurrence of propagating spiral waves in multicellular organisms is associated with key biological functions. Now this type of wave has also been observed in dense bacterial populations, probably resulting from non-reciprocal cell–cell interactions.

In semiconductors, accessing nonlinear interactions between excitons strongly coupled to light will be key for quantum technologies. Here, in atomic bilayers of MoS₂, new types of excitons are discovered showing strong inter-excitonic interactions.

Here, the authors demonstrate that a secondary electron electron-beam-induced current imaging technique in a scanning transmission electron microscope can be applied to spatially resolve the atomic scale electron density in an encapsulated WSe₂ monolayer.

Hexagonal boron nitride is a common component of 2D heterostructures. Defects implanted in boron nitride crystals can be used to perform spatially resolved sensing of properties, including temperature, magnetism and current.

How intrinsic cell properties such as stiffness contribute to cell-cell junction stabilization is not well described. Here they show that higher levels of intrinsic cell mechanics at the cortex, cytoskeleton and nucleus of neighboring cells promote junctional maturation.

Antibiotic persisters are phenotypic variants within an isogenic bacterial population that are transiently tolerant to antibiotic treatment. Here, the authors provide evidence that cytoplasmic acidification, amplified by a compromised respiratory complex I, can act as a signaling hub for perturbed metabolic homeostasis in antibiotic persisters.

The authors use long-term satellite tracking to project climate-induced shifts in whale shark distributions and understand their potential future risk of ship-strike. Under high-emission scenarios, the movement of sharks to current range-edge habitat is linked to 15,000-fold increased co-occurrence with ships.

Since the discovery of proton radioactivity in ^53mCo, there has been no direct measurement of its branching ratio. Here the authors report the first measurement of the weak proton decay in ^53mCo by combining results from advanced detection systems.

Here, the authors fabricate a device that integrates multiple computer-generated holograms into a single colour print. Under white light, a colour image is seen, whereas illumination with a red, green, or blue beam from a handheld laser pointer projects three different holograms onto a distant screen.

Dense-water formation around Antarctica could be reduced as climate change alters sea-ice formation and circulation patterns. This study shows there has been an over 40% reduction in dense-water formation in the Weddell Sea since 1992, which could affect global overturning circulation.

Saccadic suppression is frequently attributed to active suppressive signals derived from eye movement commands. Here, the authors show that visual-only mechanisms starting in the retina can account for perceptual saccadic suppression properties without the need for motor-based suppression commands.

A comprehensive study of the Kepler-138 system reveals the twin nature of Kepler-138 c and d and the presence of a fourth planet. Remarkably, the warm-temperate planet Kepler-138 d is probably composed of 50% volatiles by volume, indicative of a water world, rather than a rocky world, despite its small ~1.5 R_⊕ size.

J.-K. Kim et al. study vertical Josephson junctions where the weak link is T_d-WTe₂ and the superconductor is NbSe₂. The use of an inversion-symmetry-breaking T_d-WTe₂ weak link allows the authors to demonstrate the intrinsic origin of the observed Josephson non-reciprocity in these devices.

Graphene-based Hall magnetometers can be used to study the magnetization of two-dimensional ferromagnets.

Existing approaches to modulating the properties of 2D materials typically involve heterostructuring or exposure to external fields. Here, the authors propose a gate-free non-contact approach to tuning the properties of a 2D semiconductor via the image interaction due to proximity to a neutral patterned structure.

Class F receptors are therapeutic targets in human disease and understanding their structural changes during receptor activation may provide important pharmacological insight. Here, the authors combine computational and experimental methods to identify a molecular switch in TM6/7 of Class F receptors that mediates receptor activation.

Moiré lattice reconstruction on mesoscopic length scales gives rise to diverse exciton signatures within emergent domains of different dimensionality.

The icy surface compositions, as revealed by JWST, of small bodies beyond the orbit of Neptune can be classified into three groups that can be related to the ice retention lines in the early Solar System, possibly before the planets migrated.

Immune checkpoint inhibitor treatment improves overall survival in metastatic urothelial cancer, but response of individual patients varies significantly. Authors here perform whole-genome DNA and bulk RNA sequencing on samples from metastatic tumours and based on these data, they set up a single metric, T cell-to-stroma enrichment (TSE) score, that reflects the relative abundance of T cells versus stromal cells and their products, accurately predicting therapeutic outcome.

This is a Protocol for fluorescent intrabody localization microscopy imaging, which enables single-particle tracking of proteins in living cells, using unique nanobodies to capture protein conformer subpopulations. This is followed by nanoclustering analysis using spatiotemporal indexing to analyze their spatiotemporal clustering.

The transcriptional regulator YAP shuttles rapidly between the cytoplasm and nucleus, but whether and how dynamics such as amplitude and frequency affect target gene transcription is unclear. Here, using live imaging of endogenous YAP and target-gene transcription, the authors show that YAP-dependent signalling is encoded through rapid and concerted changes in the nucleo-cytoplasmic distribution of YAP.

The Hunga Tonga eruption represents a natural experiment, being a clearly identifiable near-point source producing gravity waves across a broad range of spatiotemporal and frequency scales, observed by a diverse array of instruments worldwide.

Haplotypes in CNR1, the gene encoding the cannabinoid receptor CB1, are known to influence HDL cholesterol levels. Here Feng and colleagues identify rs806371 as a novel regulatory element reducing CNR1 gene expression and as the causal allele driving the association between CNR1 and HDL cholesterol levels in humans.

Refraction between anisotropic media is still an unexplored phenomenon. Here, the authors investigate the propagation of hyperbolic phonon polaritons traversing α-MoO3 nanoprisms, showing a bending-free refraction effect and sub-diffractional focusing with foci size as small as 1/50 of the light wavelength in free space.

Networks of atom–cavity systems necessarily require that single atoms sit near dielectric interfaces. Real-time monitoring of caesium atoms just 100 nm from the surface of a micro-toroid resonator now demonstrates that the Casimir effect plays an important role in these systems.

Omar Albagha, Stuart Ralston and colleagues report the identification of three new loci associated with risk for Paget's disease of bone.