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Showing 1–50 of 53 results

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Asgard archaea shed light on the evolutionary origins of the eukaryotic ubiquitin-ESCRT machinery

The ESCRT pathway is crucial for membrane remodelling in eukaryotes. Here, Hatano et al. explore the phylogeny, structure, and biochemistry of homologues of the ESCRT machinery and the associated ubiquitylation system in Asgard archaea, the closest living relatives of eukaryotes.

Tomoyuki Hatano
Saravanan Palani
Mohan Balasubramanian
ResearchOpen Access13 Jun 2022
Nature Communications

Volume: 13, P: 1-16
Numerical dating of Precambrian–Cambrian boundary

G. S. Odin
N. H. Gale
P. Pasteels
Reviews06 Jan 1983
Nature

Volume: 301, P: 21-23
Chemical and Serological Relationships of Certain Bacterial Polysaccharides Containing Sialic Acid

GUY T. BARRY
TIEN-HU TSAI
FRANCIS P. CHEN
Research27 Feb 1960
Nature

Volume: 185, P: 597-598
The ATR inhibitor ceralasertib potentiates cancer checkpoint immunotherapy by regulating the tumor microenvironment

The ATR inhibitor ceralasertib has shown clinical activity in combination with immune-checkpoint inhibitors in several cancer types. Here the authors report the anti-tumor activity and the immunomodulatory changes, dependent on up-regulation of type I interferon pathway, following intermittent ATR inhibition in preclinical cancer models.

Elizabeth L. Hardaker
Emilio Sanseviero
Simon T. Barry
ResearchOpen Access24 Feb 2024
Nature Communications

Volume: 15, P: 1-20
A virtual platform for automated hybrid organic-enzymatic synthesis planning

The integration of organic and enzymatic synthesis enhances molecule construction efficiency. Here, the authors present ChemEnzyRetroPlanner, an AI-driven platform for automated hybrid synthesis planning, improving synthesis route efficiency and sustainability.

Xiaorui Wang
Xiaodan Yin
Tingjun Hou
ResearchOpen Access26 Nov 2025
Nature Communications

Volume: 16, P: 1-16
Purification and Characterization of Carcino-embryonic Antigens of the Human Digestive System

J. KRUPEY
P. GOLD
S. O. FREEDMAN
Research01 Jul 1967
Nature

Volume: 215, P: 67-68
Sialic Acid of Uterine Muscle Membrane: Reappraisal of the Serotonin Receptor of Smooth Muscle

P. M. CARROLL
D. D. SEREDA
Research17 Feb 1968
Nature

Volume: 217, P: 667-668
Occurrence of n-Nonadecanoic Acid in Ox Perinephric Fat

R. P. HANSEN
F. B. SHORLAND
N. JUNE COOKE
Research05 Nov 1955
Nature

Volume: 176, P: 882
A Sulphated Mucopolysaccharide in Human Dentine

P. PINCUS
Research29 Jul 1950
Nature

Volume: 166, P: 187
Neuromorphic olfactory perception chips: towards universal odour recognition and cognition

This Review discusses the design and functionality of neuromorphic olfactory perception chips, focusing on key technologies, including sensing materials, device structures and signal processing algorithms. The authors also highlight the practical applications and future prospects of these chips in various fields.

Yuxin Zhao
Juan Wang
Wenjie Liang
Reviews28 Oct 2025
Nature Reviews Electrical Engineering

Volume: 2, P: 755-772
A closed Candidatus Odinarchaeum chromosome exposes Asgard archaeal viruses

The closed chromosome of an Asgard archaeon, Candidatus Odinarchaeum yellowstonii LCB_4, revealed CRISPR spacers, which were used to identify archaeal viruses.

Daniel Tamarit
Eva F. Caceres
Thijs J. G. Ettema
ResearchOpen Access27 Jun 2022
Nature Microbiology

Volume: 7, P: 948-952
Stratigraphy of the Beacon Supergroup between the Olympus and Boomerang Ranges, Victoria Land, Antarctica

B. C. McKELVEY
P. N. WEBB
B. P. KOHN
Research12 Sept 1970
Nature

Volume: 227, P: 1126-1128
Development of an ObLiGaRe Doxycycline Inducible Cas9 system for pre-clinical cancer drug discovery

CRISPR/Cas9 technology has revolutionised the ability of scientists to make genetically modified cells and animal models. Here, the authors make a Tet-On genetically modified mouse using the Streptococcus pyogenes Cas9 and demonstrate that it can be used for generation of mice with lung cancer.

Anders Lundin
Michelle J. Porritt
Marcello Maresca
ResearchOpen Access29 Sept 2020
Nature Communications

Volume: 11, P: 1-16
Unique mobile elements and scalable gene flow at the prokaryote–eukaryote boundary revealed by circularized Asgard archaea genomes

The recovery of two circularized genomes of the Heimdallarchaeum species from hydrothermal vent enrichment cultures reveals that these Asgard archaea carry diverse mobile genetic elements, such as an integrative viral genome and aloposons. These mobile genetic elements contain several bacteria- and phage-derived genes, modulating the shuffling of information between bacteria and archaea, and potentially influencing eukaryogenesis.

Fabai Wu
Daan R. Speth
Victoria J. Orphan
ResearchOpen Access13 Jan 2022
Nature Microbiology

Volume: 7, P: 200-212
Cell Membrane of Uterine Smooth Muscle

P. M. CARROLL
D. D. SEREDA
Research17 Feb 1968
Nature

Volume: 217, P: 666-667
Breakthrough: a first-in-class virtual simulator for dose optimization of ACE inhibitors in translational cardiovascular medicine

Benjamin K. Schneider
Jessica Ward
Jonathan P. Mochel
ResearchOpen Access26 Feb 2023
Scientific Reports

Volume: 13, P: 1-18
Inference and reconstruction of the heimdallarchaeial ancestry of eukaryotes

Analyses of multiple phylogenetic marker datasets of Asgard archaea provide insight into the transition from prokaryotes to eukaryotes, specifically placing eukaryotes within Asgard archaea and as a sister lineage to Hodarchaeales.

Laura Eme
Daniel Tamarit
Thijs J. G. Ettema
ResearchOpen Access14 Jun 2023
Nature

Volume: 618, P: 992-999
Leveraging language model for advanced multiproperty molecular optimization via prompt engineering

Designing molecules in drug design is challenging as it requires optimizing multiple, potentially competing qualities. Wu and colleagues present a prompt-based molecule optimization method that can be trained from single-property data.

Zhenxing Wu
Odin Zhang
Tingjun Hou
Research21 Oct 2024
Nature Machine Intelligence

Volume: 6, P: 1359-1369
Saccharin may act as a tumour promoter by inhibiting metabolic cooperation between cells

J. E. Trosko
B. Dawson
C. C. Chang
Research08 May 1980
Nature

Volume: 285, P: 109-110
Nd–Sr isotopic and REE constraints on the genesis of hydrothermal manganese crusts in the Galapagos

N. Clauer
P. Stille
W. S. Moore
Research25 Oct 1984
Nature

Volume: 311, P: 743-745
<33,000-yr K–Ar dating of the volcano–tectonic horst of the Isle of Ischia, Gulf of Naples

P-Y. Gillot
S. Chiesa
L. Vezzoli
Research16 Sept 1982
Nature

Volume: 299, P: 242-245
Unusual distribution of biological markers in an Australian crude oil

R. P. Philp
T. D. Gilbert
Research16 Sept 1982
Nature

Volume: 299, P: 245-247
Achromatic Non-Interferometric Single Grating Neutron Dark-Field Imaging

M. Strobl
J. Valsecchi
J. Capek
ResearchOpen Access23 Dec 2019
Scientific Reports

Volume: 9, P: 1-7
An international 20 country patient and physician survey of the usability and acceptability of Stepped Care pathway in Parkinson’s disease

K. Poplawska-Domaszewicz
C. Rodriguez-Blazquez
K. Ray Chaudhuri
ResearchOpen Access13 Nov 2025
Scientific Reports

Volume: 15, P: 1-9
Variants at IRF5-TNPO3, 17q12-21 and MMEL1 are associated with primary biliary cirrhosis

Katherine Siminovitch and colleagues report replication and fine-mapping studies for primary biliary cirrhosis. They identify three loci newly associated with susceptibility to this autoimmune liver disease.

Gideon M Hirschfield
Xiangdong Liu
Katherine A Siminovitch
Research18 Jul 2010
Nature Genetics

Volume: 42, P: 655-657
Professor Stokes on Light

P. G. TAIT
Books & Arts02 Jun 1887
Nature

Volume: 36, P: 98-99
Snow and Ice Flora ¹

MARY P. MERRIFIELD
News26 Jul 1883
Nature

Volume: 28, P: 304-305
A novel inherently hydrophobic and physicomechanically robust coconut oil-based polyurethane-modified mortar

Jason Jon Joshua B. Paraguya
Roger G. Dingcong Jr
Arnold A. Lubguban
ResearchOpen Access19 Nov 2025
Scientific Reports

Volume: 15, P: 1-14
Deconstructing synthetic biology across scales: a conceptual approach for training synthetic biologists

Developing biotechnologies to address society’s challenges requires integrating concepts across disciplines, posing challenges to educating students with diverse expertise. In this Perspective the authors create a framework for synthetic biology training that deconstructs biotechnologies across spatial scales.

Ashty S. Karim
Dylan M. Brown
Julius B. Lucks
ReviewsOpen Access26 Jun 2024
Nature Communications

Volume: 15, P: 1-14
A high black-hole-to-host mass ratio in a lensed AGN in the early Universe

JWST/NIRSpec observations of Abell2744-QSO1 show a high black-hole-to-host mass ratio in the early Universe, which indicates that we are seeing the black hole in a phase of rapid growth, accreting at 30% of the Eddington limit.

Lukas J. Furtak
Ivo Labbé
Christina C. Williams
Research14 Feb 2024
Nature

Volume: 628, P: 57-61
Most of the photons that reionized the Universe came from dwarf galaxies

An analysis of eight ultra-faint galaxies during the epoch of reionization with absolute magnitudes between −17 mag and −15 mag shows that most of the photons that reionized the Universe come from dwarf galaxies.

Hakim Atek
Ivo Labbé
Katherine E. Whitaker
Research28 Feb 2024
Nature

Volume: 626, P: 975-978
International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways

Primary biliary cirrhosis is an autoimmune liver disease with poor therapeutic options. Here Cordell et al. a perform meta-analysis of European genome-wide association studies identifying six novel risk loci and a number of potential therapeutic pathways.

Heather J. Cordell
Younghun Han
Katherine A. Siminovitch
ResearchOpen Access22 Sept 2015
Nature Communications

Volume: 6, P: 1-11
Identification of arterial oxygen intermittency in oximetry data

Paulo P. Galuzio
Alhaji Cherif
Peter Kotanko
ResearchOpen Access26 Sept 2022
Scientific Reports

Volume: 12, P: 1-10
Detection of stellar light from quasar host galaxies at redshifts above 6

Images and spectroscopy obtained by the JWST from two HSC-SSP quasars show massive, compact and disc-like galaxies, indicating that the relation between black holes and their host galaxies was in place less than a billion years after the Big Bang.

Xuheng Ding
Masafusa Onoue
Jinyi Yang
Research28 Jun 2023
Nature

Volume: 621, P: 51-55
Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease

Konstantinos Lazaridis, Carl Anderson and colleagues report results of a genome-wide association study of primary sclerosing cholangitis (PSC). They identify four new susceptibility loci for PSC and quantify the correlation of common genetic variation shared between PSC and inflammatory bowel diseases.

Sun-Gou Ji
Brian D Juran
Carl A Anderson
Research19 Dec 2016
Nature Genetics

Volume: 49, P: 269-273
Quantification of nitrogen oxides emissions from build-up of pollution over Paris with TROPOMI

A. Lorente
K. F. Boersma
M. C. Krol
ResearchOpen Access27 Dec 2019
Scientific Reports

Volume: 9, P: 1-10
The IBD interactome: an integrated view of aetiology, pathogenesis and therapy

IBD is a complex disease characterized by multiple interacting pathogenic components. In this Perspectives, the authors advocate studying the 'IBD interactome' to build a molecular network of IBD, and discuss new concepts and tools to implement an unbiased systems approach that could facilitate development of novel therapies.

Heitor S. P. de Souza
Claudio Fiocchi
Dimitrios Iliopoulos
Reviews23 Aug 2017
Nature Reviews Gastroenterology & Hepatology

Volume: 14, P: 739-749
The Chaotic Terrains of Mercury Reveal a History of Planetary Volatile Retention and Loss in the Innermost Solar System

J. Alexis P. Rodriguez
Gregory J. Leonard
Mark Sykes
ResearchOpen Access16 Mar 2020
Scientific Reports

Volume: 10, P: 1-14
The placental lipidome of maternal antenatal depression predicts socio-emotional problems in the offspring

Gerard Wong
Jacquelyn M. Weir
Neerja Karnani
ResearchOpen Access04 Feb 2021
Translational Psychiatry

Volume: 11, P: 1-11
Phosphoproteomic analysis of Syk kinase signaling in human cancer cells reveals its role in cell–cell adhesion

R M Larive
S Urbach
N Bettache
Research04 May 2009
Oncogene

Volume: 28, P: 2337-2347
Sociodemographic and psychopathologic predictors of first incidence of DSM-IV substance use, mood and anxiety disorders: results from the Wave 2 National Epidemiologic Survey on Alcohol and Related Conditions

B F Grant
R B Goldstein
W M Compton
Research22 Apr 2008
Molecular Psychiatry

Volume: 14, P: 1051-1066
Single agent and combination studies of pralatrexate and molecular correlates of sensitivity

M Serova
I Bieche
E Raymond
ResearchOpen Access21 Dec 2010
British Journal of Cancer

Volume: 104, P: 272-280
Relation of placental alkaline phosphatase expression in human term placenta with maternal and offspring fat mass

Birgit Hirschmugl
Sarah Crozier
Rohan M Lewis
Research13 Jun 2018
International Journal of Obesity

Volume: 42, P: 1202-1210
Sex-specific longitudinal associations of screen viewing time in children at 2–3 years with adiposity at 3–5 years

Natarajan Padmapriya
Izzuddin M. Aris
Falk Müller-Riemenschneider
Research02 Apr 2019
International Journal of Obesity

Volume: 43, P: 1334-1343
Genes and (auto)immunity in primary biliary cirrhosis

C Selmi
P Invernizzi
M E Gershwin
Reviews21 Jul 2005
Genes & Immunity

Volume: 6, P: 543-556
A Delphi consensus statement for digital surgery

Kyle Lam
Michael D. Abràmoff
Sanjay Purkayastha
ResearchOpen Access19 Jul 2022
npj Digital Medicine

Volume: 5, P: 1-9
Association of primary biliary cirrhosis with variants in the CLEC16A, SOCS1, SPIB and SIAE immunomodulatory genes

G M Hirschfield
G Xie
K A Siminovitch
Research19 Jan 2012
Genes & Immunity

Volume: 13, P: 328-335
Pathway-based analysis of primary biliary cirrhosis genome-wide association studies

S P Kar
M F Seldin
C I Amos
Research07 Feb 2013
Genes & Immunity

Volume: 14, P: 179-186
Which anthropometric measures best reflect neonatal adiposity?

L-W Chen
M-T Tint
Y S Lee
Research09 Oct 2017
International Journal of Obesity

Volume: 42, P: 501-506
The relationship between maternal 25-hydroxyvitamin D status in pregnancy and childhood adiposity and allergy: an observational study

V T Boyle
E B Thorstensen
P N Baker
Research04 Aug 2017
International Journal of Obesity

Volume: 41, P: 1755-1760

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