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Showing 1–50 of 104 results

Advanced filters: Author: Shoji Yoshida Clear advanced filters

Disentangling multiple gas kinematic drivers in the Perseus galaxy cluster

Kinematic measurements of the Perseus galaxy cluster reveal two drivers of gas motions: a small-scale driver in the inner core associated with black-hole feedback and a large-scale driver in the outer core powered by mergers.

Marc Audard
Hisamitsu Awaki
Elena Bellomi
Research28 Jan 2026
Nature

P: 1-5
Fungal Metabolite, Epoxyquinol B, Crosslinks Proteins by Epoxy-thiol Conjugation

Hiroshi Kamiyama
Takeo Usui
Hiroyuki Osada
Research01 Feb 2008
The Journal of Antibiotics

Volume: 61, P: 94-97
Deciphering state-dependent immune features from multi-layer omics data at single-cell resolution

A single-cell multiomic immune cell atlas from 235 Japanese, including patients with COVID-19 and healthy individuals, linked with host genetics including germline and somatic mutation, plasma proteomics and metagenomics data reveals that immune cells are dynamically regulated in a cell state-dependent manner.

Ryuya Edahiro
Go Sato
Yukinori Okada
ResearchOpen Access28 Jul 2025
Nature Genetics

Volume: 57, P: 1905-1921
The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force

Genetic mechanisms influencing COVID-19 susceptibility are not well understood. Here, the authors analyzed whole blood RNA-seq data of 465 Japanese individuals with COVID-19, highlighting thousands of fine-mapped variants affecting expression and splicing of genes, as well as the presence of COVID-19 severity-interaction eQTLs.

Qingbo S. Wang
Ryuya Edahiro
Yukinori Okada
ResearchOpen Access22 Aug 2022
Nature Communications

Volume: 13, P: 1-19
DOCK2 is involved in the host genetics and biology of severe COVID-19

A genome-wide association study highlights a variant in DOCK2, which is common in East Asian populations but rare in Europeans, as a host genetic risk factor for severe COVID-19.

Ho Namkoong
Ryuya Edahiro
Yukinori Okada
ResearchOpen Access08 Aug 2022
Nature

Volume: 609, P: 754-760
Mechanically activated switching of Si-based single-molecule junction as imaged with three-dimensional dynamic probe

Mechanically induced conformational modulation can be used to control the conductance of single molecules junctions, but it is hard to be realized due to broken junctions. Here, the authors probe three-dimensional dynamics of Si/single-molecule/Si junctions, whose conductance shows a binary change.

Miki Nakamura
Shoji Yoshida
Hidemi Shigekawa
ResearchOpen Access06 Oct 2015
Nature Communications

Volume: 6, P: 1-8
CT-based phenotyping of COVID-19: cluster analysis of pulmonary and extrapulmonary imaging markers from a multicentre retrospective cohort study

Shiro Otake
Naoya Tanabe
Koichi Fukunaga
ResearchOpen Access26 Nov 2025
Scientific Reports

Volume: 15, P: 1-13
Hereditary progressive dystonia with marked diurnal fluctuation caused by mutations in the GTP cyclohydrolase I gene

Hiroshi Ichinose
Tamae Ohye
Toshiharu Nagatsu
Research01 Nov 1994
Nature Genetics

Volume: 8, P: 236-242
ADAR1 as a prognostic marker for patients with colorectal cancer and synchronous liver metastasis and a predictor of chemotherapy efficacy

Kaori Nitta
Kunitoshi Shigeyasu
Toshiyoshi Fujiwara
ResearchOpen Access23 Jul 2025
Scientific Reports

Volume: 15, P: 1-9
Real-space imaging of transient carrier dynamics by nanoscale pump–probe microscopy

By combining advanced ultrashort-pulse laser technology with scanning tunneling microscopy, scientists demonstrate that they can directly image transient carrier dynamics in nanostructures in real space.

Yasuhiko Terada
Shoji Yoshida
Hidemi Shigekawa
Research24 Oct 2010
Nature Photonics

Volume: 4, P: 869-874
Chlorine and potassium enrichment in the Cassiopeia A supernova remnant

XRISM observations show the presence of odd-numbered elements chlorine and potassium in Cas A. These findings suggest that stellar activity plays an important role in cosmic chemical evolution, enriching space with elements vital for planets and life.

Marc Audard
Hisamitsu Awaki
Manan Agarwal
ResearchOpen Access04 Dec 2025
Nature Astronomy

Volume: 10, P: 144-153
Possible Involvement of Rho-Kinase in Aldosterone-Induced Vascular Smooth Muscle Cell Remodeling

Kayoko Miyata
Hirofumi Hitomi
Akira Nishiyama
Research01 Jul 2008
Hypertension Research

Volume: 31, P: 1407-1413
An ultrafast diamond nonlinear photonic sensor

Quantum sensors based on NV centers in diamond can reach sub-nanometer spatial resolution, but high temporal resolution remains a challenge. Here the authors report an ultrafast electro-optical sensor using NV centers, demonstrating surface electric field sensing with nanometer–femtosecond resolution.

Daisuke Sato
Junjie Guo
Muneaki Hase
ResearchOpen Access25 Sept 2025
Nature Communications

Volume: 16, P: 1-8
Blood DNA virome associates with autoimmune diseases and COVID-19

Analysis of the blood DNA virome in patients with COVID-19 and autoimmune disease associates endogenous HHV-6 (eHHV-6) and high anellovirus load with increased disease risk, most notably for systemic lupus erythematosus. eHHV-6 carriers show a distinct immune response.

Noah Sasa
Shohei Kojima
Yukinori Okada
ResearchOpen Access03 Jan 2025
Nature Genetics

Volume: 57, P: 65-79
Early post-mortem formation of carbonate concretions around tusk-shells over week-month timescales

Hidekazu Yoshida
Atsushi Ujihara
Richard Metcalfe
ResearchOpen Access15 Sept 2015
Scientific Reports

Volume: 5, P: 1-7
Red cell glyoxalase I polymorphism in Japanese: Confirmation of a lowGLO ¹ frequency

Masatsugu Hashimoto
Shoji Harada
Keiichi Omoto
Research01 Jun 1978
Japanese journal of human genetics

Volume: 23, P: 139-143
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity

Peripheral blood mononuclear cells from 73 Japanese patients with coronavirus disease 2019 (COVID-19) and 75 healthy controls were analyzed using single-cell transcriptomics. Combining these data with genotyping data highlights the interplay between host genetics and the immune response in modulating disease severity.

Ryuya Edahiro
Yuya Shirai
Yukinori Okada
ResearchOpen Access24 Apr 2023
Nature Genetics

Volume: 55, P: 753-767
Stratified wind from a super-Eddington X-ray binary is slower than expected

The XRISM Resolve spectrum of the galactic neutron star X-ray binary, GX 13+1, reveals one of the densest winds ever seen in absorption lines.

Marc Audard
Hisamitsu Awaki
Missagh Mehdipour
ResearchOpen Access17 Sept 2025
Nature

Volume: 646, P: 57-61
Highly coupled ATP synthesis by F₁-ATPase single molecules

Yannick Rondelez
Guillaume Tresset
Hiroyuki Noji
Research17 Feb 2005
Nature

Volume: 433, P: 773-777
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Microscopic basis for the band engineering of Mo_1−xW_xS₂-based heterojunction

Shoji Yoshida
Yu Kobayashi
Hidemi Shigekawa
ResearchOpen Access07 Oct 2015
Scientific Reports

Volume: 5, P: 1-6
p53-armed oncolytic adenovirus induces apoptosis in pancreatic cancer-associated stellate cells via macropinocytosis

Takeyoshi Nishiyama
Hiroshi Tazawa
Toshiyoshi Fujiwara
ResearchOpen Access28 Nov 2025
Cancer Gene Therapy

P: 1-13
Dielectric Properties of Poly(γ-benzyl L-glutamate-co-L-leucine) and Poly(γ-methyl L-glutamate-co-L-leucine) in the Solid State

Kunio Hikichi
Shoji Yamahata
Akihiro Tsutsumi
Research01 Dec 1985
Polymer Journal

Volume: 17, P: 1241-1244
Development and validation of predictive model for emesis in cervical cancer patients receiving concurrent chemoradiotherapy based on multi-institutional retrospective study

Kensuke Yoshida
Hajime Morita
Munetoshi Sugiura
ResearchOpen Access27 Oct 2025
Scientific Reports

Volume: 15, P: 1-9
Real-space coherent manipulation of electrons in a single tunnel junction by single-cycle terahertz electric fields

Carrier-envelope-phase-controlled single-cycle terahertz pulses can induce coherent electron tunnelling either from a Pt/Ir nanotip to a graphite sample or vice versa. The pulses enable ultrafast nonlinear manipulation of electrons at the atomic scale.

Katsumasa Yoshioka
Ikufumi Katayama
Jun Takeda
Research07 Nov 2016
Nature Photonics

Volume: 10, P: 762-765
Probing ultrafast spin dynamics with optical pump–probe scanning tunnelling microscopy

Spin dynamics in semiconductor heterostructures can be probed by a modified scanning tunnelling microscopy technique with a temporal resolution of a few picoseconds.

Shoji Yoshida
Yuta Aizawa
Hidemi Shigekawa
Research29 Jun 2014
Nature Nanotechnology

Volume: 9, P: 588-593
Homogeneous climate variability across East Antarctica over the past three glacial cycles

O. Watanabe
J. Jouzel
N. Yoshida
Research03 Apr 2003
Nature

Volume: 422, P: 509-512
Nanoscale terahertz spectroscopy

The advent of terahertz spectroscopy schemes that offer single-photon sensitivity, femtosecond time resolution and nanometre spatial resolution is creating new opportunities for investigating ultrafast charge dynamics in semiconductor structures.

Hidemi Shigekawa
Shoji Yoshida
Osamu Takeuchi
News & Views31 Oct 2014
Nature Photonics

Volume: 8, P: 815-817
Structural insights into the subtype-selective antagonist binding to the M₂ muscarinic receptor

A structural study supported by molecular dynamics simulations describes the basis of receptor-subtype selectivity of a small-molecule antagonist of the human muscarinic M₂ receptor.

Ryoji Suno
Sangbae Lee
Takuya Kobayashi
Research12 Nov 2018
Nature Chemical Biology

Volume: 14, P: 1150-1158
Profiling of runs of homozygosity from whole-genome sequence data in Japanese biobank

Aye Ko Ko Minn
Motomichi Matsuzaki
Gen Tamiya
ResearchOpen Access03 Apr 2025
Journal of Human Genetics

Volume: 70, P: 287-296
Characteristics of physical activity during beginner-level group tennis lessons and the effect daily activity

Ryo Kawakami
Satoshi Yamakawa
Ken Nakata
ResearchOpen Access02 Jan 2024
Scientific Reports

Volume: 14, P: 1-9
Diagnostic utility of high-mobility group box 1 for acute exacerbations of idiopathic pulmonary fibrosis

Naoki Hamada
Shoji Tokunaga
Yoichi Nakanishi
ResearchOpen Access05 Nov 2025
Scientific Reports

Volume: 15, P: 1-10
Single-cell multi-omics analysis identifies two distinct phenotypes of newly-onset microscopic polyangiitis

Autoimmune vasculitis can be heterogeneous in terms of immune cell involvement. Here the authors use a single cell transcriptomics approach to characterise a group of microscopic polyangiitis patients that could be split into two groups typified by monocyte or Interferon associated gene expression.

Masayuki Nishide
Kei Nishimura
Atsushi Kumanogoh
ResearchOpen Access11 Oct 2023
Nature Communications

Volume: 14, P: 1-14
Expansions of intronic TTTCA and TTTTA repeats in benign adult familial myoclonic epilepsy

This study identifies TTTCA- and TTTTA-repeat expansions in benign adult familial myoclonic epilepsy. Cortical neurons from affected people exhibit RNA foci containing these expanded repeats, suggesting RNA toxicity as the mechanism underlying disease pathogenesis.

Hiroyuki Ishiura
Koichiro Doi
Shoji Tsuji
Research05 Mar 2018
Nature Genetics

Volume: 50, P: 581-590
Structured ionized winds shooting out from a quasar at relativistic speeds

Observations of a luminous quasar from the high-resolution spectrometer Resolve aboard XRISM revealed highly inhomogeneous wind structure outflowing from a supermassive black hole, which probably consists of up to a million clumps.

Marc Audard
Hisamitsu Awaki
Yerong Xu
Research14 May 2025
Nature

Volume: 641, P: 1132-1136
Polymerization of DL-Phenylalanine N-Carboxyanhydride by Multifunctional Pyridine Derivatives

Yukio Imanishi
Shoji Nagaoka
Toshinobu Higashimura
Research01 Aug 1973
Polymer Journal

Volume: 4, P: 644-650
Clinical impact of short limited lumbar fusion for adult spinal deformity with postural and radiological abnormalities

Hideaki Nakajima
Hideaki Matsuo
Akihiko Matsumine
ResearchOpen Access14 Nov 2022
Scientific Reports

Volume: 12, P: 1-9
The umami receptor T1R1–T1R3 heterodimer is rarely formed in chickens

Yuta Yoshida
Fuminori Kawabata
Shoji Tabata
ResearchOpen Access10 Jun 2021
Scientific Reports

Volume: 11, P: 1-10
Simulating metabolic pathways to enhance interpretations of metabolome genome-wide association studies

Shun Kodate
Mitsuharu Sato
Kengo Kinoshita
ResearchOpen Access16 May 2025
Scientific Reports

Volume: 15, P: 1-11
The bulk motion of gas in the core of the Centaurus galaxy cluster

X-ray spectroscopic observations of the Centaurus galaxy cluster with the X-Ray Imaging and Spectroscopy Mission satellite show that the hot gas flows along the line of sight relative to the central galaxy.

Marc Audard
Hisamitsu Awaki
Anwesh Majumder
Research12 Feb 2025
Nature

Volume: 638, P: 365-369
Late-onset spastic ataxia phenotype in a patient with a homozygous DDHD2 mutation

Hiroshi Doi
Masao Ushiyama
Kunihiro Yoshida
ResearchOpen Access24 Nov 2014
Scientific Reports

Volume: 4, P: 1-7
ATPase copper transporting beta contributes to cisplatin resistance as a regulatory factor of extracellular vesicles in head and neck squamous cell carcinoma

Tatsuo Ogawa
Kisho Ono
Soichiro Ibaragi
ResearchOpen Access17 Oct 2025
Cancer Gene Therapy

Volume: 33, P: 39-54
The effect of nitrogen lone-pair interaction on the conduction in a single-molecule junction with amine-Au bonding

Yoshihiro Sugita
Atsushi Taninaka
Hidemi Shigekawa
ResearchOpen Access27 Mar 2018
Scientific Reports

Volume: 8, P: 1-8
Intermediate-band dynamics of quantum dots solar cell in concentrator photovoltaic modules

Tomah Sogabe
Yasushi Shoji
Yoshitaka Okada
ResearchOpen Access25 Apr 2014
Scientific Reports

Volume: 4, P: 1-7
Modulation of electrical potential and conductivity in an atomic-layer semiconductor heterojunction

Yu Kobayashi
Shoji Yoshida
Yasumitsu Miyata
ResearchOpen Access12 Aug 2016
Scientific Reports

Volume: 6, P: 1-8
Fibrocyte-like cells mediate acquired resistance to anti-angiogenic therapy with bevacizumab

Acquired resistance to anti-angiogenic drugs, including bevacizumab, may occur in cancer patients. In this study the authors identify in the tumour microenvironment, fibrocyte-like cells derived from the bone marrow that mediate the resistance to bevacizumab through the production of FGF2.

Atsushi Mitsuhashi
Hisatsugu Goto
Yasuhiko Nishioka
ResearchOpen Access04 Dec 2015
Nature Communications

Volume: 6, P: 1-15
Long-term Surgical Outcomes of Epiretinal Membrane in Patients with Retinitis Pigmentosa

Yasuhiro Ikeda
Noriko Yoshida
Tatsuro Ishibashi
ResearchOpen Access13 Aug 2015
Scientific Reports

Volume: 5, P: 1-7
Syngenetic rapid growth of ellipsoidal silica concretions with bitumen cores

Hidekazu Yoshida
Ryusei Kuma
Richard Metcalfe
ResearchOpen Access19 Feb 2021
Scientific Reports

Volume: 11, P: 1-11
Identification and replication of sex-dimorphic protein quantitative trait loci across multiple ancestries and their associations with diseases

Youngjune Bhak
Vasilis Raptis
Albert Tenesa
ResearchOpen Access28 Aug 2025
Scientific Reports

Volume: 15, P: 1-16

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