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Showing 1–50 of 55 results

Advanced filters: Author: Silke Schmidt Clear advanced filters

Epidemiology and treatment of malignant ovarian germ cell and sex cord stromal tumors in germany: a population-based cancer registry study from 2016 – 2021

Dennis Jung
Sinaida Branscheidt
Annette Hasenburg
ResearchOpen Access18 Dec 2025
Scientific Reports

Volume: 15, P: 1-7
Ischemic brain infarcts, white matter hyperintensities, and cognitive impairment are increased in patients with Atrial Fibrillation

Krisai et al. compare brain structure and cognitive function in elderly patients with and without atrial fibrillation using brain MRI and cognitive testing. They find that atrial fibrillation is associated with more brain lesions and lower cognitive function, but the cognitive impairment occurs primarily through direct effects of the arrhythmia rather than through brain damage.

Philipp Krisai
Stefanie Aeschbacher
Nico Ruckstuhl
ResearchOpen Access27 Jan 2026
Communications Medicine

P: 1-10
Human contributions to global soundscapes are less predictable than the acoustic rhythms of wildlife

Analysis of soundscape data from 139 globally distributed sites reveals that sounds of biological origin exhibit predictable rhythms depending on location and season, whereas sounds of anthropogenic origin are less predictable. Comparisons between paired urban–rural sites show that urban green spaces are noisier and dominated by sounds of technological origin.

Panu Somervuo
Tomas Roslin
Otso Ovaskainen
ResearchOpen Access09 Jul 2025
Nature Ecology & Evolution

Volume: 9, P: 1585-1598
Erratum: Spatio–temporal frequency domains and their relation to cytochrome oxidase staining in cat visual cortex

Doron Shoham
Mark Hübener
Tobias Bonhoeffer
Amendments and Corrections20 Mar 1997
Nature

Volume: 386, P: 302
A catalog of genetic loci associated with kidney function from analyses of a million individuals

Trans-ancestry meta-analysis of estimated glomerular filtration rate (eGFR) from 1,046,070 individuals identifies 264 associated loci, providing a resource of molecular targets for translational research of chronic kidney disease.

Matthias Wuttke
Yong Li
Cristian Pattaro
Research31 May 2019
Nature Genetics

Volume: 51, P: 957-972
Mutations in respiratory complex I promote antibiotic persistence through alterations in intracellular acidity and protein synthesis

Antibiotic persisters are phenotypic variants within an isogenic bacterial population that are transiently tolerant to antibiotic treatment. Here, the authors provide evidence that cytoplasmic acidification, amplified by a compromised respiratory complex I, can act as a signaling hub for perturbed metabolic homeostasis in antibiotic persisters.

Bram Van den Bergh
Hannah Schramke
Matthias Heinemann
ResearchOpen Access27 Jan 2022
Nature Communications

Volume: 13, P: 1-18
Ancient mitogenomics clarifies radiation of extinct Mascarene giant tortoises (Cylindraspis spp.)

Christian Kehlmaier
Eva Graciá
Uwe Fritz
ResearchOpen Access25 Nov 2019
Scientific Reports

Volume: 9, P: 1-7
Dexamethasone-mediated protection from drug cytotoxicity: association with p21^WAF1/CIP1 protein accumulation?

Ulrike Naumann
Silke Durka
Michael Weller
Research22 Sept 1998
Oncogene

Volume: 17, P: 1567-1575
The Anglo-Saxon migration and the formation of the early English gene pool

Archaeogenetic study of ancient DNA from medieval northwestern Europeans reveals substantial increase of continental northern European ancestry in Britain, suggesting mass migration across the North Sea during the Early Middle Ages.

Joscha Gretzinger
Duncan Sayer
Stephan Schiffels
ResearchOpen Access21 Sept 2022
Nature

Volume: 610, P: 112-119
Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores

Known genetic loci account for only a fraction of the genetic contribution to Alzheimer’s disease. Here, the authors have performed a large genome-wide meta-analysis comprising 409,435 individuals to discover 6 new loci and demonstrate the efficacy of an Alzheimer’s disease polygenic risk score.

Itziar de Rojas
Sonia Moreno-Grau
Agustín Ruiz
ResearchOpen Access07 Jun 2021
Nature Communications

Volume: 12, P: 1-16
Interleukin 7 receptor α chain ( IL7R ) shows allelic and functional association with multiple sclerosis

Simon G Gregory
Silke Schmidt
Jonathan L Haines
Research29 Jul 2007
Nature Genetics

Volume: 39, P: 1083-1091
Integrin-linked kinase controls retinal angiogenesis and is linked to Wnt signaling and exudative vitreoretinopathy

Integrin-linked kinase (ILK) is an important mediator of integrin signaling. Here Park et al. show that mice with endothelial-specific deletion of Ilk develop vascular defects that resemble familial exudative vitreoretinopathy, and identify mutations in ILK in patients with exudative vitreoretinopathy suggesting a potential role in human pathogenesis.

Hongryeol Park
Hiroyuki Yamamoto
Ralf H. Adams
ResearchOpen Access20 Nov 2019
Nature Communications

Volume: 10, P: 1-14
SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care

Here the authors use RT-qPCR and mass spectrometry to analyze longitudinal blood samples from intensive care unit (ICU) COVID-19 patients and controls. They find that viral RNA and pentraxin-3 predict 28-day ICU mortality and that galectin-3-binding protein is an interaction partner of SARS-CoV-2 spike glycoprotein with antiviral properties.

Clemens Gutmann
Kaloyan Takov
Manuel Mayr
ResearchOpen Access07 Jun 2021
Nature Communications

Volume: 12, P: 1-17
A fungal pathogen induces systemic susceptibility and systemic shifts in wheat metabolome and microbiome composition

The fungal plant pathogen Zymoseptoria tritici is a major threat to wheat yield. Here Seybold et al. show that Z. tritici can suppress immune responses not only in infected tissue but also on other leaves, a phenomenon termed “systemic induced susceptibility” that is correlated with systemic changes in metabolite accumulation.

Heike Seybold
Tobias J. Demetrowitsch
Eva H. Stukenbrock
ResearchOpen Access20 Apr 2020
Nature Communications

Volume: 11, P: 1-12
Concerted dynamics of metallo-base pairs in an A/B-form helical transition

Metal-mediated base pairs expand the repertoire of nucleic acid structures and dynamics. Here, the authors prepared a metallo-DNA duplex including two C-Hg(II)-T base pairs separated by six normal Watson-Crick base pairs and investigated its solution structure and dynamics using NMR spectroscopy.

Olivia P. Schmidt
Simon Jurt
Nathan W. Luedtke
ResearchOpen Access23 Oct 2019
Nature Communications

Volume: 10, P: 1-11
Mitochondrial protein import receptors in Kinetoplastids reveal convergent evolution over large phylogenetic distances

Protein translocation into the mitochondrion is a conserved process in all eukaryotes. Here, Mani et al. describe a non-conventional translocase complex in Trypanosoma bruceiand propose that protein import receptors were recruited to the core complex after the divergence of the major eukaryotic supergroups.

Jan Mani
Silvia Desy
André Schneider
ResearchOpen Access26 Mar 2015
Nature Communications

Volume: 6, P: 1-12
A new class of homoserine lactone quorum-sensing signals

Acyl-homoserine lactone (AHL) quorum sensing allows population-dependent control of gene expression in numerous bacterial species. Many AHL quorum-sensing systems are known, all of which use fatty acid groups to provide AHL specificity. This paper reports the discovery that some bacteria make a non-fatty AHL by using enzymes related to the fatty AHL synthase pathway, thus greatly expanding the realm of signal possibilities.

Amy L. Schaefer
E. P. Greenberg
Caroline S. Harwood
Research18 Jun 2008
Nature

Volume: 454, P: 595-599
Combined pathological, microbiological and virological evaluation of vitreous aspirates: a retrospective evaluation of 374 vitrectomy specimens with non-neoplastic disorders

Mihaly Sulyok
Kristina Schmauder
Falko Fend
ResearchOpen Access08 Oct 2025
Eye

Volume: 39, P: 3262-3268
Correction: Corrigendum: A common coding variant in CASP8 is associated with breast cancer risk

Angela Cox
Alison M Dunning
Douglas F Easton
Amendments and Corrections01 May 2007
Nature Genetics

Volume: 39, P: 688
Author Correction: The Anglo-Saxon migration and the formation of the early English gene pool

Joscha Gretzinger
Duncan Sayer
Stephan Schiffels
Amendments and CorrectionsOpen Access17 Oct 2022
Nature

Volume: 611, P: E3
Direct measurement of individual phonon lifetimes in the clathrate compound Ba_7.81Ge_40.67Au_5.33

Phonon lifetime is a fundamental parameter of thermal transport however its determination is challenging. Using inelastic neutron scattering and the neutron resonant spin-echo technique, Lory et al. determine the acoustic phonon lifetime in a single crystal of clathrate Ba7.81Ge40.67Au5.33.

Pierre-François Lory
Stéphane Pailhès
Marc de Boissieu
ResearchOpen Access08 Sept 2017
Nature Communications

Volume: 8, P: 1-10
Serum metabolome associated with severity of acute traumatic brain injury

Traumatic brain injury is associated with changes to the metabolome. Here the authors show that acute traumatic brain injury has distinctive serum metabolic patterns which may suggest protective changes of systemic lipid metabolism aiming to maintain lipid homeostasis in the brain.

Ilias Thomas
Alex M. Dickens
Tommaso Zoerle
ResearchOpen Access10 May 2022
Nature Communications

Volume: 13, P: 1-15
Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota

Andre Franke and colleagues perform a genome-wide association study for the gut microbiome, examining the influence of host genetics on overall microbial variation and individual taxa. They find significant associations at the VDR (vitamin D receptor) locus and observe correlations between microbiota and metabolites of VDR, including bile acids.

Jun Wang
Louise B Thingholm
Andre Franke
Research10 Oct 2016
Nature Genetics

Volume: 48, P: 1396-1406
Ultra high frequency ultrasound enables real-time visualization of blood supply from chorioallantoic membrane to human autosomal dominant polycystic kidney tissue

Jan Schueler
Jonas Kuenzel
Silke Haerteis
ResearchOpen Access02 May 2024
Scientific Reports

Volume: 14, P: 1-13
Role of morphogenetic factors in metastasis of mammary carcinoma cells

Silke Meiners
Volker Brinkmann
Walter Birchmeier
Research21 Jan 1998
Oncogene

Volume: 16, P: 9-20
Lung recruitment state during induction of general anaesthesia in a prospective observational clinical study in patients without and with obesity

Silke Borgmann
Kim Linz
Stefan Schumann
ResearchOpen Access21 Mar 2025
Scientific Reports

Volume: 15, P: 1-9
Paternal microbiota manipulation influences offspring microbial colonization and development in a sex role-reversed pipefish

Kim-Sara Wagner
Frédéric Salasc
Olivia Roth
ResearchOpen Access22 Aug 2025
Scientific Reports

Volume: 15, P: 1-16
A common coding variant in CASP8 is associated with breast cancer risk

Angela Cox
Alison M Dunning
Douglas F Easton
Research11 Feb 2007
Nature Genetics

Volume: 39, P: 352-358
Carbon dioxide reduction by photosynthesis undetectable even during phytoplankton blooms in two lakes

Karla Münzner
Silke Langenheder
Eva S. Lindström
ResearchOpen Access19 Aug 2023
Scientific Reports

Volume: 13, P: 1-10
The quantitative and condition-dependent Escherichia coli proteome

A large-scale quantification of Escherichia coli proteomes across 22 experimental conditions.

Alexander Schmidt
Karl Kochanowski
Matthias Heinemann
Research01 Jan 2016
Nature Biotechnology

Volume: 34, P: 104-110
Potential of PEDOT:PSS as a hole selective front contact for silicon heterojunction solar cells

Sara Jäckle
Martin Liebhaber
Klaus Lips
ResearchOpen Access19 May 2017
Scientific Reports

Volume: 7, P: 1-8
Author Correction: Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores

Itziar de Rojas
Sonia Moreno-Grau
Agustín Ruiz
Amendments and CorrectionsOpen Access09 Feb 2023
Nature Communications

Volume: 14, P: 1-2
A precise performance-based reimbursement model for the multi-centre NAPKON cohorts – development and evaluation

Katharina S. Appel
Chin Huang Lee
Jörg Janne Vehreschild
ResearchOpen Access13 Jun 2024
Scientific Reports

Volume: 14, P: 1-11
Epidemiology of 7375 children and adolescents hospitalized with COVID-19 in Germany, reported via a prospective, nationwide surveillance study in 2020–2022

Maren Doenhardt
Markus Hufnagel
Ulrich Zügge
ResearchOpen Access02 Jan 2024
Scientific Reports

Volume: 14, P: 1-15
A Role for Decorin in the Structural Organization of Periodontal Ligament

Lari Häkkinen
Silke Strassburger
Hannu Larjava
Research01 Dec 2000
Laboratory Investigation

Volume: 80, P: 1869-1880
Spatiotemporal changes in riverine input into the Eocene North Sea revealed by strontium isotope and barium analysis of bivalve shells

Jorit F. Kniest
David Evans
Jacek Raddatz
ResearchOpen Access20 Nov 2024
Scientific Reports

Volume: 14, P: 1-11
Serum anti-NMDA receptor antibodies are linked to memory impairment 12 months after stroke

Friederike A. Arlt
Pia S. Sperber
Peter Bartenstein
ResearchOpen Access30 Oct 2024
Molecular Psychiatry

Volume: 30, P: 1359-1368
Myocilin and optineurin coding variants in Hispanics of Mexican descent with POAG

Kristin K McDonald
Karen Abramson
R Rand Allingham
Research29 Jul 2010
Journal of Human Genetics

Volume: 55, P: 697-700
Empathic responses to unknown others are modulated by shared behavioural traits

Silke Anders
Christian Beck
Martin Lotze
ResearchOpen Access06 Feb 2020
Scientific Reports

Volume: 10, P: 1-9
An explorative cross-sectional analysis of mental health shame and help-seeking intentions in different lifestyles

Claudia Helmert
Toni Fleischer
Georg Schomerus
ResearchOpen Access04 Jul 2023
Scientific Reports

Volume: 13, P: 1-12
Association of polygenic score and the involvement of cholinergic and glutamatergic pathways with lithium treatment response in patients with bipolar disorder

Azmeraw T. Amare
Anbupalam Thalamuthu
Bernhard T. Baune
ResearchOpen Access11 Jul 2023
Molecular Psychiatry

Volume: 28, P: 5251-5261
Biomarker and cognitive decline in atrial fibrillation: a prospective cohort study

Philipp Krisai
Magdalena Eberl
Ramun Schmid
ResearchOpen Access15 Apr 2025
Scientific Reports

Volume: 15, P: 1-12
Fifty years of limnological data on Lake Stechlin, a temperate clearwater lake

Sabine Wollrab
Silke R. Schmidt
Rainer Koschel
ResearchOpen Access18 Jun 2025
Scientific Data

Volume: 12, P: 1-10
Inflammatory biotype of ADHD is linked to chronic stress: a data-driven analysis of the inflammatory proteome

Isabel Schnorr
Anne Siegl
Carmen Schiweck
ResearchOpen Access18 Jan 2024
Translational Psychiatry

Volume: 14, P: 1-14
Familial cleft tongue caused by a unique translation initiation codon variant in TP63

Julia Schmidt
Gudrun Schreiber
Bernd Wollnik
ResearchOpen Access11 Oct 2021
European Journal of Human Genetics

Volume: 30, P: 211-218
A bead-based multiplex assay covering all coronaviruses pathogenic for humans for sensitive and specific surveillance of SARS-CoV-2 humoral immunity

Daniel Stern
Tanja C. Meyer
Brigitte G. Dorner
ResearchOpen Access09 Dec 2023
Scientific Reports

Volume: 13, P: 1-22
TILTomorrow today: dynamic factors predicting changes in intracranial pressure treatment intensity after traumatic brain injury

Shubhayu Bhattacharyay
Florian D. van Leeuwen
Tommaso Zoerle
ResearchOpen Access02 Jan 2025
Scientific Reports

Volume: 15, P: 1-18
Results of a multicenter phase I/II trial of TCRαβ and CD19-depleted haploidentical hematopoietic stem cell transplantation for adult and pediatric patients

Wolfgang A. Bethge
Matthias Eyrich
Peter Lang
ResearchOpen Access24 Dec 2021
Bone Marrow Transplantation

Volume: 57, P: 423-430
Differential modulation of malignant peripheral nerve sheath tumor growth by omega-3 and omega-6 fatty acids

George A Mashour
Stephanie N Drissel
Andreas Kurtz
Research14 Feb 2005
Oncogene

Volume: 24, P: 2367-2374
Automated detection of the HER2 gene amplification status in Fluorescence in situ hybridization images for the diagnostics of cancer tissues

Falk Zakrzewski
Walter de Back
Pia Hönscheid
ResearchOpen Access03 Jun 2019
Scientific Reports

Volume: 9, P: 1-12

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