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Finite momentum superconducting pairing refers to a class of unconventional superconducting states where Cooper pairs acquire a non-zero momentum. Here the authors report a new superconducting state in bulk 4Hb-TaS₂, where magnetic fields induce finite momentum pairing via magnetoelectric coupling.

Antimatter remains an enigma – its absence in the universe is hitherto unexplained. Here, the authors report a breakthrough in the ability to study antihydrogen atoms to test fundamental symmetries. Antihydrogen atoms can now be accumulated at CERN at the previously unattainable rate of 2000 per hour.

This analysis looks at the impacts and outcomes from installing solar arrays on agricultural land, finding that these ‘agrisolar’ projects can displace food production but simultaneously provide economic security and offset water use.

Federated learning (FL) algorithms have emerged as a promising solution to train models for healthcare imaging across institutions while preserving privacy. Here, the authors describe the Federated Tumor Segmentation (FeTS) challenge for the decentralised benchmarking of FL algorithms and evaluation of Healthcare AI algorithm generalizability in real-world cancer imaging datasets.

This Article introduces a framework to assess water systems as potential sources of energy flexibility using energy storage metrics and levelized costs. Through case studies of a desalination plant, a water distribution network and a wastewater treatment plant, it explores the benefits and challenges of flexible load operation, highlighting how electricity tariffs may influence facility investment decisions.

The advantage of living in cities compared with rural areas with respect to height and BMI in children and adolescents has generally become smaller globally from 1990 to 2020, except in sub-Saharan Africa.

This Consensus Statement clarifies the existing subset-based nomenclature for T cells. Furthermore, it proposes an alternative modular nomenclature that is designed to be brief and flexible and to avoid ambiguity and unwanted implications. The authors also provide guidance on how T cell nomenclature should be described in research papers.

The vaginal microbiome is a critical determinant of health. Here, the authors present VIRGO2, a gene catalog describing these microbial communities and analyze vaginal metagenomes and metatranscriptomes to derive insights into their function and ecology.

Biohydrogen production technologies effectively use waste biomass resources and produce high-purity hydrogen. Here, authors present and evaluate a continuous pilot-scale biohydrogen production system based on spectrum coupling, thermal effect, and multiphase flow properties of hydrogen production.

Electrification is a decarbonization strategy that has the potential to reduce pollutant emissions and improve air quality. Here the authors evaluate CO₂ and air quality co-benefits of electrification scenarios in the United States and find that electrification can substantially lower CO2 and improve ozone and fine particulate matter regionally.

Climate change will affect the adoption of residential rooftop solar photovoltaics by changing the patterns of both electricity generation and demand. This research projects that climate change will increase the future value and optimal capacity of household rooftop solar across the United States.

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

Country-level changes in economic production and the value of non-market ecosystem benefits show unequal impacts on the global values of natural capital resulting from climate-change-induced shifts in terrestrial vegetation cover.

There are currently no licensed vaccines to prevent Group A Streptococcus (GAS) infections. In this study, the authors evaluate the immune response and preclinical efficacy of a multicomponent mRNA lipid-nanoparticle vaccine against GAS.

In mammals, the enzyme TGDS produces UDP-4-keto-6-deoxyglucose, which binds to the catalytic pocket of UDP-xylose synthase, thereby regenerating the essential NAD⁺ cofactor of UDP-xylose synthase in conditions of low NAD⁺.

Acetic acid efficiently depolymerizes aliphatic and aromatic epoxy-amine thermosets used in carbon fibre-reinforced polymers (CFRPs) to yield recoverable monomers and pristine carbon fibres, which, based on process modelling, techno-economic analysis and life cycle assessment, could enable industrial recycling of CFRPs.

Using multi-ancestry genome-wide association study and fine-mapping, 298 loci and 36 credible genes are identified in the aetiology of bipolar disorder.

Van Dooijeweert et al. conducted a prospective study on the clinical implementation of artificial-intelligence-assisted detection of sentinel lymph node metastasis in persons with breast cancer and report on its effects, including on time and cost.

Estimates from the Global Dietary Database indicated that 2.2 million new type 2 diabetes and 1.2 million new cardiovascular disease cases were attributable to sugar-sweetened beverages worldwide in 2020, with the highest burdens in sub-Saharan Africa, Latin America and the Caribbean.

Carbon–carbon bonds are ubiquitous in lignin, limiting monomer yields from current depolymerization strategies mainly targeting C–O bonds. Now, a bifunctional hydrocracking approach uses a Pt/zeolite catalyst to break C–C bonds in lignin waste, achieving monocyclic hydrocarbon yields up to 54 C%.

A pore-modulated pyrolysis reactor that enables catalyst-free and energy-efficient upcycling of plastic waste is demonstrated. The graded-pore structure imposes molecular-weight-dependent transport barriers, establishing a gating effect that enhances product selectivity and yields aviation fuel precursor (C₈–C₁₈) with high efficiency.

Preparing room temperature phosphorescent materials from biomass is important but challenging. Here, the authors report the use of liquid monomer 2-hydroxyethyl acrylate for dissolution of lignin and subsequent solvent-free preparation of lignin-based RTP materials.

An economic evaluation of the E-MOTIVE intervention for postpartum hemorrhage (PPH) compared with usual care in 210,132 women, carried out from a healthcare system perspective, uncovered the cost per case of severe PPH prevented and cost per disability-adjusted life-year averted.

The success of Chimeric antigen receptor (CAR) T-cell therapy in solid tumours is hampered by the scarcity of suitable targets and suboptimal activation of the engineered T cells in the hostile microenvironment of the tumours. Here authors identify CD276 as target in childhood rhabdomyosarcoma, which, when combined into a bicistronic construct with a known target, FGF4R, allows enhanced tumour killing.

Whole-genome sequencing of 3,171 cultivated and 195 wild chickpea accessions is used to construct a chickpea pan-genome, providing insight into chickpea evolution and enabling breeding strategies that could improve crop productivity.

Here the authors show in male mice that acute and chronic complex simulated galactic cosmic radiation exposure differentially reorganized prefrontal cortex neurotransmitter networks in vivo, which was associated with cognitive deficits.

Reservoir computing designs recurrent networks that simultaneously buffer inputs and form nonlinear features. Here, authors propose a configurable scheme with better scaling where memory buffer and nonlinear features are in separate circuits. It can be efficiently implemented in neuromorphic hardware.

Batteries are promising to support energy systems based on intermittent renewable energy, yet their investment attractiveness remains low. Using a techno-economic model, Stephan et al. find that returns can be increased and risks reduced if batteries are used for multiple stationary applications.

The historical and spatial patterns of the phosphorus budget and phosphorus use efficiency by country and crop type are reported, and used to determine phosphorus pollution and scarcity challenges.

Decisions frequently involve sequential searches through options until the right moment to stop and make a decision has been reached. This study shows that participants’ searches stop too early because of misguided expectations of future options.

T cell responses can be generated to either pathogen infection or from priming with a vaccine. Here the authors compare T cell generation, phenotype and single cell transcriptome of participants vaccinated with a mpox vaccine or infected with the virus showing that the virus induced T cells showed more effective function and phenotype.

A resource of microbial metabolic models reveals how an individual’s gut microbiome influences drug metabolism.