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Direct growth of graphene on h-BN is desired to improve device performance. Here, the authors demonstrate the direct growth of large-area and continuous graphene/h-BN vertical heterostructures via a co-segregation approach.

2D diamond is expected to show superior properties compared to bulk diamond, but its synthesis remains challenging. Here, the authors report a high-temperature high-pressure method to fabricate thermally stable 2D diamond via laser-heating of few-layer graphene in a diamond anvil cell, providing relevant insights into the 2D graphene-diamond transformation mechanisms.

Owing to their valley degree of freedom, atomically thin transition metal dichalcogenides show promise for valleytronics. Here, the authors leverage the dark excitons of two-dimensional van der Waals heterostructures to demonstrate a microsecond valley polarization memory effect.

Single-cell RNA-sequencing of seven mouse developmental stages identifies lineage-specific and shared regulatory programs controlling cell-fate decisions. Cross-species analysis associates differentiation potency with ribosomal protein gene expression.

Wafer-scale 3R-MoS₂ with high phase purity is achieved through a homoepitaxy strategy, which demonstrates ferroelectricity and holds promise for multifunctional integration.

The Mexican axolotl is a well-established tetrapod model for regeneration and development. Here the authors report a scRNA-seq method to profile neotenic, metamorphic and limb development stages, highlighting unique perturbation patterns of cell type-related gene expression throughout metamorphosis.

Pressure-induced modulation of interlayer coupling and elastic constant in two-dimensional layered materials is quantitatively described through a unified chain model, offering insights into the tunable mechanical behaviors under extreme conditions.

The fabrication of artificial crystals by reassembling monolayer semiconductors enables on-demand engineering of their excitonic properties. Here, the authors report an efficient stacking method to fabricate millimetre-scale van der Waals homo-/hetero-crystals, demonstrating enhanced monolayer-like photoluminescence emission and quadrupolar interlayer exciton emission.

Cui et al. report analogue photoelectronic reservoir computing with IGZO synaptic transistors as the reservoir and TaOX-based memristor array as the output layer. A receptive field inspired encoding scheme is implemented to simplify the feature extraction for dynamic vision processing.

.Sensitive detection of weak acoustic signals at nanometer scale is challenging. Here, the authors present an acoustic detection system based on a single molecule as a probe, where frequency and amplitude of acoustic vibrations can be extracted from its minute variations in distance to the surface of a plasmonic gold nanorod.

An integrated smart capsule that encapsulates an array of electrochemical sensors can provide real-time, continuous and multiplexed monitoring of the gastrointestinal tract.

NiPS₃, a van der Waals antiferromagnet exhibits exciton emission with a very sharp linewidth. The exact origin of this is has been a subject of active debate. Here, Wang et al study the behavior of this sharp exciton peak under applied magnetic fields, and find a Zeeman-like splitting, indicating the exciton has triplet-singlet character.

An electronic skin that is capable of long-term monitoring of vital signs and molecular biomarkers in sweat can—with the help of machine learning—be used to classify stress responses with high accuracy and predict state anxiety levels with high reliability.

2D excitonic devices hold potential for on-chip optoelectronic applications. Here, the authors report high-speed in-plane electrical modulations of the excitonic distribution in monolayer semiconductor/Au electrode junctions, showing switching times as low as 5 ns at room temperature.

Mechano-Raman spectroscopy is demonstrated by using interlayer phonons of atomic-layer vibrators to drive synchronous motion of the metallic plasmonic structure that can then be detected. The modulated light scattering brings out the information that cannot be accessed by optical Raman spectroscopy.

CO₂ electroreduction to multi-carbon products in acids remains challenging due to the low efficiency and poor stability of C–C coupling. Here, the authors show that asymmetric CO binding at confined nanointerfaces enhances multi-carbon production, improves CO₂ utilization, and limits H₂ evolution.

An in situ phase-separation method at microscale level creates stretchable superelastic porous nanocomposite conductors, reduces conductive filler usage and enables strain-resilient wireless wearable and implantable bioelectronics.

Catalysis is a crucial strategy for improving the performance of sulfur cathodes in Li–S batteries, yet few strategies have been established to design effective catalysts. Here, by uncovering a volcano-shaped trend between polysulfide adsorption and catalytic rate in transition-metal-doped ZnS, a highly efficient ternary sulfide is developed.

Broad-band emission of self-trapped exciton in low-dimensional perovskite is prospective for white LED, yet rational design new white perovskite remains challenge. Here, the authors develop an atom-substituting strategy to trigger exciton self-tapping in perovskites and reveal the mechanism behind.

Microwell-seq is used to generate single-cell, whole-body expression landscapes of zebrafish, Drosophila and earthworm. A deep-learning model, Nvwa, predicts gene expression from DNA sequence and identifies regulatory programs shared across eight species.

Current wearable and implantable biosensors still face challenges to improve sensitivity, stability and scalability. Here the authors report inkjet-printable, mass-producible core–shell nanoparticle-based biosensors to monitor a broad range of biomarkers.

A wearable sweat sensor powered by a flexible solar cell can continuously collect multimodal physicochemical data—glucose, pH, sodium ion, sweat rate and skin temperature—across indoor and outdoor physical activities for over 12 h.

A reagentless, wireless, wearable aptamer nanobiosensor interfaced with a gold nanoparticle-MXene-based electrode enables the selective, automatic and non-invasive analysis of the female hormone oestradiol in sweat during menstrual cycles with subpicomolar sensitivity.

A wearable electrochemical biosensor can continuously detect, in sweat during physical exercise and at rest, trace levels of multiple metabolites and nutrients, including all essential amino acids and vitamins.

Tripterygium wilfordii is a medical plant that can produce antitumor activity compound triptolide. Here, the authors assemble its genome and identify a cytochrome P450 that can catalyze oxidation of a methyl to the acid moiety of dehydroabietic acid in triptolide biosynthesis by integrating multi-omics data.

A wearable electrochemical patch for the real-time monitoring of the biomarker C-reactive protein in sweat detects elevated concentrations of the protein in patients with acute or chronic inflammation.

Liquid bioelectronics based on a permanent fluidic magnet made from three-dimensional assembled magnetic colloidal particles can be injected into the surface of the heart for cardiovascular monitoring and subsequently retrieved after use.

A tetherless microelectronic system can be controlled by wireless power to direct locomotion and perform grasp and release tasks.

A correlated blinking phenomenon is discovered in two-dimensional bilayer semiconductor heterostructures, whereby a bright emission state occurs in one monolayer while a dark state occurs in the other, and vice versa.

Skin-like flexible electronics (electronic skin) has great potential in medical practices to enable continuous tracking of physical and biochemical information. Xu et al. review the integration of AI methods and electronic skins, especially how data collected from sensors are processed by AI to extract features for human–machine interactions and health monitoring purposes.

Single-cell transcriptome data reveal analogous gene expression patterns between renal mesangial cells and retinal pericytes and imply similarities between the molecular events that cause diabetic nephropathy and diabetic retinopathy.