Nature Search

Mycobacterium tuberculosis modulates phosphorylation of host ATP6V1E1 to promote intracellular survival

Intracellular pathogens such as Mycobacterium tuberculosis can promote their survival within infected cells by preventing lysosomal acidification. Here, the authors show that M. tuberculosis secretes a protein that promotes phosphorylation of a subunit of the host vacuolar ATPase, thus inhibiting V-ATPase assembly and lysosomal acidification.

Jianxia Chen
Fen Tang
Ruijuan Zheng
ResearchOpen Access06 Feb 2026
Nature Communications

Volume: 17, P: 1-17
Plastic mulch productivity-sustainability tradeoffs and pathways toward an eco-friendly framework: insights from a global meta-analysis

This study finds that plastic mulch substantially increases crop yields but also contaminates soils and pollutes the environment. The authors propose biodegradable films, AI-driven farming, and policy reforms to address the productivity–sustainability trade-offs.

Li Wang
Shiqian Guo
Gary Y. Gan
ResearchOpen Access22 Jan 2026
Nature Communications

Volume: 17, P: 1-13
Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme

Mutations in the chromatin modifier Chd7 have been associated with CHARGE syndrome and other developmental disorders. Here the authors show that Chd7 is required for the activation of genes essential for cerebellar granule cell differentiation, and that disrupting Chd7 leads to cerebellar hypoplasia in mice.

Weijun Feng
Daisuke Kawauchi
Hai-Kun Liu
ResearchOpen Access20 Mar 2017
Nature Communications

Volume: 8, P: 1-14
Locating the missing absorption enhancement due to multi‒core black carbon aerosols

Wildfire observations reveal that 21% of black carbon aerosols contain multiple cores, and accounting for this morphology increases global absorption by 19%, highlighting a missing source of radiative forcing in current models.

Xiyao Chen
Joseph Ching
Weijun Li
ResearchOpen Access19 Nov 2025
Nature Communications

Volume: 16, P: 1-12
Molecular mechanism of cholesterol-dependent membrane fusion in SARS-CoV-2 entry

Wei Li
Mengdan Wu
Ying Lai
ResearchOpen Access17 Feb 2026
Signal Transduction and Targeted Therapy

Volume: 11, P: 1-16
A modified two-stage approach for family-based genome-wide association studies

Weijun Ma
Ying Zhou
Zhen Gu
Research22 May 2013
European Journal of Human Genetics

Volume: 22, P: 148-151
In-material physical computing based on reconfigurable microwire arrays via halide-ion segregation

This study demonstrates stable photoelectricity-induced halide segregation in epitaxial mixed-halide perovskite microwire networks on mica, verified by in-situ observations. Dynamic segregation-recovery processes and reconfigurable self-powered photoresponse reveal physical computing potential.

Dengji Li
Pengshan Xie
Johnny C. Ho
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-10
PHF8 activates transcription of rRNA genes through H3K4me3 binding and H3K9me1/2 demethylation

Covalent histone lysine modification has been linked to various DNA functions. PHF8 is a jumonji family demethylase containing a PHD domain, linked to methylated histone binding, and also to X-linked mental retardation. PHF8 is now shown to bind H3K4me3 and demethylate H3K9me1/2, a function linked here to activation of rRNA transcription.

Weijun Feng
Masato Yonezawa
Ingrid Grummt
Research07 Mar 2010
Nature Structural & Molecular Biology

Volume: 17, P: 445-450
Self-assembled superstructure alleviates air-water interface effect in cryo-EM

Air-water interface hinders cryo-EM reconstruction and achievable resolution. Here, a superstructure called GSAMs is developed to alleviate the air-water interface effect and improve the efficiency of cryo-EM analysis.

Liming Zheng
Jie Xu
Hailin Peng
ResearchOpen Access24 Aug 2024
Nature Communications

Volume: 15, P: 1-10
Microenvironment-confined kinetic elucidation and implementation of a DNA nano-phage with a shielded internal computing layer

Adding nanobodies into DNA computing has proven difficult due to there always on state. Here, the authors propose a spatial segregation-based molecular computing strategy to program nanobodies into DNA molecular computation and elucidate the kinetic mechanism of microenvironment-confined DNA molecular computation.

Decui Tang
Shuoyao He
Weihong Tan
ResearchOpen Access22 Jan 2025
Nature Communications

Volume: 16, P: 1-13
The genomic basis of geographic differentiation and fiber improvement in cultivated cotton

Genomic variations in 3,248 tetraploid cotton germplasms and multi-environmental genome-wide association analyses provide insights into the basis of geographic differentiation and fiber improvement in cultivated cotton.

Shoupu He
Gaofei Sun
Xiongming Du
Research15 Apr 2021
Nature Genetics

Volume: 53, P: 916-924
Single-cell transcriptomes reveal spatiotemporal heat stress response in maize roots

Investigating cell heterogeneity and type-specific response is essential for improving crop resilience. Here, authors generate single-cell transcriptional landscape of maize roots in response to heat stress and reveal the relationship between the cortex and the heat tolerance.

Ting Wang
Fanhua Wang
Li Pu
ResearchOpen Access02 Jan 2025
Nature Communications

Volume: 16, P: 1-17
Dissemination of IMP-4-encoding pIMP-HZ1-related plasmids among Klebsiella pneumoniae and Pseudomonas aeruginosa in a Chinese teaching hospital

Wei Feng
Dongsheng Zhou
Peiyuan Xia
ResearchOpen Access19 Sept 2016
Scientific Reports

Volume: 6, P: 1-7
Peptide-triggered conformational switch in HIV-1 RRE RNA complexes

Yuying Gosser
Thomas Hermann
Dinshaw J. Patel
Research01 Feb 2001
Nature Structural Biology

Volume: 8, P: 146-150
Perovskite computed tomography imager and three-dimensional reconstruction

A direct lead-halide perovskite CT imager has been demonstrated. The detector arrays have 980 μm absorber thickness and exhibit detection quantum efficiency of 80% and noise-equivalent dose of 153 pGy_air.

Yuhong He
Jinmei Song
Haotong Wei
Research16 Aug 2024
Nature Photonics

Volume: 18, P: 1052-1058
A convention-radiomics CT nomogram for differentiating fat-poor angiomyolipoma from clear cell renal cell carcinoma

Yanqing Ma
Weijun Ma
Peipei Pang
ResearchOpen Access25 Feb 2021
Scientific Reports

Volume: 11, P: 1-8
Differential perovskite hemispherical photodetector for intelligent imaging and location tracking

Differential spectrometers recognise different wavelength via their differential photodetector responsivity. The authors combine an 8-pixel hemispherical perovskite photodetector with neural network algorithms to realise 3D trajectory tracking and 2D location tacking with colour classification.

Xiaopeng Feng
Chenglong Li
Haotong Wei
ResearchOpen Access17 Jan 2024
Nature Communications

Volume: 15, P: 1-9
Surface Energy Driven Cubic-to-Hexagonal Grain Growth of Ge₂Sb₂Te₅ Thin Film

Yonghui Zheng
Yan Cheng
Songlin Feng
ResearchOpen Access19 Jul 2017
Scientific Reports

Volume: 7, P: 1-8
A hybrid sub-lineage of Listeria monocytogenes comprising hypervirulent isolates

Listeria monocytogenes isolates are highly heterogeneous and exhibit different levels of virulence. Here, the authors identify hypervirulent isolates that represent a hybrid sub-lineage of the major lineage II harbouring virulence factors from Listeria ivanovii and wall teichoic acids found in major lineage I.

Yuelan Yin
Hao Yao
Xin’an Jiao
ResearchOpen Access30 Sept 2019
Nature Communications

Volume: 10, P: 1-16
Deptor protects against myocardial ischemia-reperfusion injury by regulating the mTOR signaling and autophagy

Qunjun Duan
Weijun Yang
Jie Han
ResearchOpen Access19 Dec 2024
Cell Death Discovery

Volume: 10, P: 1-11
Organocatalyzed chemoselective ring-opening polymerizations

Ning Zhu
Yihuan Liu
Kai Guo
ResearchOpen Access27 Feb 2018
Scientific Reports

Volume: 8, P: 1-8
Genomic characterization of novel IncFII-type multidrug resistant plasmids p0716-KPC and p12181-KPC from Klebsiella pneumoniae

Jiao Feng
Zhe Yin
Dongsheng Zhou
ResearchOpen Access19 Jul 2017
Scientific Reports

Volume: 7, P: 1-7
Can full-cost insurance enhance agricultural economic resilience?

Hua Li
Wei Zhao
Weijun Wang
ResearchOpen Access16 Oct 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-12
Multi-omics analysis of human mesenchymal stem cells shows cell aging that alters immunomodulatory activity through the downregulation of PD-L1

Mesenchymal stem cells (MSC) are used for immunosuppressive therapy and a uniform source or heterogeneity characterisation is needed. Here the authors use multi-omics to compare human MSC from different sources and ages of donors and show differences in gene expression and immunosuppressive function.

Yuchen Gao
Ying Chi
Xiaomin Zhang
ResearchOpen Access20 Jul 2023
Nature Communications

Volume: 14, P: 1-21
Ultralong UV/mechano-excited room temperature phosphorescence from purely organic cluster excitons

Purely organic ultralong room temperature phosphorescence (URTP) attracts attention but high efficiencies are rarely achieved. Here the authors use ultrafast spectroscopy to investigate a system of 1,8-naphthalic anhydride in organic hosts and reveal that a cluster exciton forms as a transient state before the guest acts as an energy trap for the URTP state.

Xuepeng Zhang
Lili Du
Ben Zhong Tang
ResearchOpen Access14 Nov 2019
Nature Communications

Volume: 10, P: 1-10
An ALOX12–12-HETE–GPR31 signaling axis is a key mediator of hepatic ischemia–reperfusion injury

ALOX12-mediated generation of 12-HETE leads to GPR31 activation and liver injury in ischemia–reperfusion, which can be targeted in a nonhuman primate model to improve outcome.

Xiao-Jing Zhang
Xu Cheng
Hongliang Li
Research11 Dec 2017
Nature Medicine

Volume: 24, P: 73-83
Saikosaponin‑D triggers cancer cell death by targeting the PIM1/c-Myc axis to reprogram oncogenic alternative splicing

Xin Zhang
Xuehui Li
Weijun Wang
ResearchOpen Access06 Oct 2025
Cell Death Discovery

Volume: 11, P: 1-13
Optimizing the axis ratio of elliptical PCM encasement for enhanced thermal performance in radiant floor heating systems

Zhenyu Wang
Weijun Gao
Yanna Gao
ResearchOpen Access16 Mar 2025
Scientific Reports

Volume: 15, P: 1-13
Mutation of CHD7 impairs the output of neuroepithelium transition that is reversed by the inhibition of EZH2

Zhuxi Huang
Chenxi He
Weijun Feng
Research31 Mar 2025
Molecular Psychiatry

Volume: 30, P: 4094-4109
Prediction of strata settlement in undersea metal mining based on deep forest

Weijun Liu
Zida Liu
Zhixiang Liu
ResearchOpen Access18 Nov 2024
Scientific Reports

Volume: 14, P: 1-24
Impact of visual and textural characteristics of street walls on stress recovery

Nan Zhang
Lin Zhao
Weijun Gao
ResearchOpen Access02 Jul 2024
Scientific Reports

Volume: 14, P: 1-13
Mesenchymal stromal cells-derived matrix Gla protein contribute to the alleviation of experimental colitis

Yuan Feng
Yan Liao
Qi Zhang
ResearchOpen Access07 Jun 2018
Cell Death & Disease

Volume: 9, P: 1-14
Autologous transplantation of thecal stem cells restores ovarian function in nonhuman primates

Hong Chen
Kai Xia
Qiong Ke
ResearchOpen Access31 Aug 2021
Cell Discovery

Volume: 7, P: 1-16
NNT-AS1 in CAFs-derived exosomes promotes progression and glucose metabolism through miR-889-3p/HIF-1α in pancreatic adenocarcinoma

Pingping Zhang
Qun Wang
Junwei Sun
ResearchOpen Access24 Mar 2024
Scientific Reports

Volume: 14, P: 1-11
3-Hydroxy-3-methylglutaryl coenzyme A reductase genes from Glycine max regulate plant growth and isoprenoid biosynthesis

Shuai Wang
Yumei Feng
Aiqin Yue
ResearchOpen Access08 Mar 2023
Scientific Reports

Volume: 13, P: 1-14
Characterization of respiratory microbial dysbiosis in hospitalized COVID-19 patients

Huanzi Zhong
Yanqun Wang
Jincun Zhao
ResearchOpen Access13 Apr 2021
Cell Discovery

Volume: 7, P: 1-14
Studies on the metabolism and degradation of vancomycin in simulated in vitro and aquatic environment by UHPLC-Triple-TOF-MS/MS

Mengsi Cao
Yanru Feng
Lianfeng Ai
ResearchOpen Access19 Oct 2018
Scientific Reports

Volume: 8, P: 1-13
Computed tomography imaging-guided radiotherapy by targeting upconversion nanocubes with significant imaging and radiosensitization enhancements

Huaiyong Xing
Xiangpeng Zheng
Jianlin Shi
ResearchOpen Access29 Apr 2013
Scientific Reports

Volume: 3, P: 1-9
Genetic characterization of two fully sequenced multi-drug resistant plasmids pP10164-2 and pP10164-3 from Leclercia adecarboxylata

Fengjun Sun
Dongsheng Zhou
Peiyuan Xia
ResearchOpen Access23 Sept 2016
Scientific Reports

Volume: 6, P: 1-9
An open science resource for establishing reliability and reproducibility in functional connectomics

Xi-Nian Zuo
Jeffrey S Anderson
Michael P Milham
ResearchOpen Access09 Dec 2014
Scientific Data

Volume: 1, P: 1-13
Foot-and-mouth disease virus infection inhibits LGP2 protein expression to exaggerate inflammatory response and promote viral replication

Zixiang Zhu
Chuntian Li
Haixue Zheng
ResearchOpen Access13 Apr 2017
Cell Death & Disease

Volume: 8, P: e2747
FBW7 regulates endothelial functions by targeting KLF2 for ubiquitination and degradation

Rui Wang
Yan Wang
Ping Wang
Research19 Mar 2013
Cell Research

Volume: 23, P: 803-819

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