Nature Search

Hepatic HMGCS2-derived β-hydroxybutyrate attenuates hippocampal insulin resistance and neuroinflammation to promote MASLD-induced cognitive function

Fatty liver disease may harm the brain by starving it of a protective fuel. This study shows that restoring this fuel, BHB, can rescue memory and brain health, revealing a direct liver-brain link and a promising treatment target.

Lijuan Nie
Jing Sun
Xiqiao Zhou
ResearchOpen Access10 Jan 2026
Communications Biology

P: 1-13
Revealing the role of interface disorder in modulating critical current density of Josephson junctions

Chuanbing Han
Huihui Sun
Zheng Shan
ResearchOpen Access06 Jan 2026
npj Computational Materials

P: 1-12
An elite allele TaDT1-A^hapI enhances drought tolerance via mediating autophagic pathways in wheat

This study identifies the TaDT1-A^hapI allele conferring drought resistance without yield penalty. Its 899-bp promoter deletion evades TaMYC2 repression and thereby enhances autophagy-mediated stomatal dynamics and water-use efficiency, providing a potential breeding target.

Xingbei Liu
Jinpeng Li
Zhaorong Hu
ResearchOpen Access16 Jul 2025
Nature Communications

Volume: 16, P: 1-17
ISSAAC-seq enables sensitive and flexible multimodal profiling of chromatin accessibility and gene expression in single cells

ISSAAC-seq offers a sensitive and modular tool for joint profiling gene expression and chromatin accessibility in single cells.

Wei Xu
Weilong Yang
Xi Chen
Research15 Sept 2022
Nature Methods

Volume: 19, P: 1243-1249
Pan-genomic analysis highlights genes associated with agronomic traits and enhances genomics-assisted breeding in alfalfa

Pan-genome analysis of 24 alfalfa accessions identifies key structural variations associated with salt tolerance and quality traits and provides resources for genomics-assisted breeding in alfalfa.

Fei He
Shuai Chen
Qingchuan Yang
Research23 Apr 2025
Nature Genetics

Volume: 57, P: 1262-1273
Pan-genome bridges wheat structural variations with habitat and breeding

The pan-genome of 17 wheat cultivars grown in China is explored, providing insights into the breeding history of wheat in East Asia.

Chengzhi Jiao
Xiaoming Xie
Xueyong Zhang
Research27 Nov 2024
Nature

Volume: 637, P: 384-393
A chromosomal-scale genome assembly of modern cultivated hybrid sugarcane provides insights into origination and evolution

Modern sugarcane cultivars have complicated genome due to interspecific crosses and multiple backcrossing. Here, the authors report the haplotype-resolved, chromosome-level genome assembly of a modern hybrid sugarcane cultivar and reveal the expansion of genes related to sugar accumulation and smut resistance.

Yixue Bao
Qing Zhang
Muqing Zhang
ResearchOpen Access08 Apr 2024
Nature Communications

Volume: 15, P: 1-14
A comparative study of asleep and awake deep brain stimulation robot-assisted surgery for Parkinson’s disease

Hai Jin
Shun Gong
He Pan
ResearchOpen Access05 Oct 2020
npj Parkinson's Disease

Volume: 6, P: 1-7
The comparison of bone mineral density of femoral head between non-hip fracture side and hip fracture side

Xianlong Li
Yueyang Xu
Yongqian Fan
ResearchOpen Access03 Aug 2020
Scientific Reports

Volume: 10, P: 1-7
Angular dependent anisotropic terahertz response of vertically aligned multi-walled carbon nanotube arrays with spatial dispersion

Yixuan Zhou
Yiwen E.
Li Wang
ResearchOpen Access14 Dec 2016
Scientific Reports

Volume: 6, P: 1-10
TMEM232 is required for the formation of sperm flagellum and male fertility in mice

Xinying Cai
Hui Zhang
Fengsong Wang
ResearchOpen Access08 Nov 2024
Cell Death & Disease

Volume: 15, P: 1-18
Spatial-frequency feature fusion network for small dataset fine-grained image classification

Yongfei Guo
Bo Li
Weilong Dong
ResearchOpen Access18 Mar 2025
Scientific Reports

Volume: 15, P: 1-14
Global characterization of megakaryocytes in bone marrow, peripheral blood, and cord blood by single-cell RNA sequencing

Weilong Zhang
Changjian Yan
Hongmei Jing
Research01 Jun 2022
Cancer Gene Therapy

Volume: 29, P: 1636-1647
Single-cell exome sequencing reveals polyclonal seeding and TRPS1 mutations in colon cancer metastasis

Jianqiang Cai
Weilong Zhang
Hong Zhao
ResearchOpen Access23 Sept 2024
Signal Transduction and Targeted Therapy

Volume: 9, P: 1-16
Study on the reduction of residual stress in laser cladding layers through groove texture

Changlong Zhao
Chen Ma
Zihao Zhang
ResearchOpen Access10 Jul 2024
Scientific Reports

Volume: 14, P: 1-20
Association of visceral adiposity index and chronic pain in US adults: a cross-sectional study

Weilong Xu
Ruizhen Shi
Wei Feng
ResearchOpen Access17 Mar 2025
Scientific Reports

Volume: 15, P: 1-11
Construction of a potential microRNA and messenger RNA regulatory network of acute lung injury in mice

Yufeng Zhang
Weilong Jiang
Xudong Han
ResearchOpen Access17 Jan 2022
Scientific Reports

Volume: 12, P: 1-12
Human-computer interaction interface design of flight simulator based on situation awareness

Zhengyi Shen
Guoqiang Chen
Deyang Han
ResearchOpen Access13 Nov 2024
Scientific Reports

Volume: 14, P: 1-23
Association between composite dietary antioxidant index and erectile dysfunction among American adults: a cross-sectional study

Huajun Zhu
Si Chen
Zhuangcheng Huang
ResearchOpen Access11 Sept 2024
Scientific Reports

Volume: 14, P: 1-10
Superficial vimentin mediates DENV-2 infection of vascular endothelial cells

Jie Yang
Lingyun Zou
Xiancai Rao
ResearchOpen Access02 Dec 2016
Scientific Reports

Volume: 6, P: 1-12
Sirt1 deficiency upregulates glutathione metabolism to prevent hepatocellular carcinoma initiation in mice

Pengxiang Qiu
Weilong Hou
Ruihong Wang
Research25 Aug 2021
Oncogene

Volume: 40, P: 6023-6033
Controllably grown single-crystal films as flexoelectric nanogenerators for continuous direct current output

Yang Li
Qinling Zhou
Zongping Shao
ResearchOpen Access29 Oct 2022
npj Flexible Electronics

Volume: 6, P: 1-7
The circadian clock gene Bmal1 facilitates cisplatin-induced renal injury and hepatization

Min Zha
Ting Tian
Liji Huang
ResearchOpen Access10 Jun 2020
Cell Death & Disease

Volume: 11, P: 1-14
Virome analysis for identification of novel mammalian viruses in bats from Southeast China

Dan Hu
Changqiang Zhu
Changjun Wang
ResearchOpen Access07 Sept 2017
Scientific Reports

Volume: 7, P: 1-12

Search

Hepatic HMGCS2-derived β-hydroxybutyrate attenuates hippocampal insulin resistance and neuroinflammation to promote MASLD-induced cognitive function

Revealing the role of interface disorder in modulating critical current density of Josephson junctions

An elite allele TaDT1-A^hapI enhances drought tolerance via mediating autophagic pathways in wheat

ISSAAC-seq enables sensitive and flexible multimodal profiling of chromatin accessibility and gene expression in single cells

Pan-genomic analysis highlights genes associated with agronomic traits and enhances genomics-assisted breeding in alfalfa

Pan-genome bridges wheat structural variations with habitat and breeding

A chromosomal-scale genome assembly of modern cultivated hybrid sugarcane provides insights into origination and evolution

A comparative study of asleep and awake deep brain stimulation robot-assisted surgery for Parkinson’s disease

The comparison of bone mineral density of femoral head between non-hip fracture side and hip fracture side

Angular dependent anisotropic terahertz response of vertically aligned multi-walled carbon nanotube arrays with spatial dispersion

TMEM232 is required for the formation of sperm flagellum and male fertility in mice

Spatial-frequency feature fusion network for small dataset fine-grained image classification

Global characterization of megakaryocytes in bone marrow, peripheral blood, and cord blood by single-cell RNA sequencing

Single-cell exome sequencing reveals polyclonal seeding and TRPS1 mutations in colon cancer metastasis

Study on the reduction of residual stress in laser cladding layers through groove texture

Association of visceral adiposity index and chronic pain in US adults: a cross-sectional study

Construction of a potential microRNA and messenger RNA regulatory network of acute lung injury in mice

Human-computer interaction interface design of flight simulator based on situation awareness

Association between composite dietary antioxidant index and erectile dysfunction among American adults: a cross-sectional study

Superficial vimentin mediates DENV-2 infection of vascular endothelial cells

Sirt1 deficiency upregulates glutathione metabolism to prevent hepatocellular carcinoma initiation in mice

Controllably grown single-crystal films as flexoelectric nanogenerators for continuous direct current output

The circadian clock gene Bmal1 facilitates cisplatin-induced renal injury and hepatization

Virome analysis for identification of novel mammalian viruses in bats from Southeast China

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