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This study reports an asymmetric single-atom catalyst in a floating photothermal platform, realising simultaneous solar-driven hydrogen production and seawater desalination in a scalable device.

Complex-frequency excitation enables non-Hermitian control on light-matter interactions, without relying on materials gain or loss. Here, authors introduce virtual gain into a whispering-gallery-mode optical microcavity to achieve three amplification regimes, mimicking the dynamics of a laser.

Inborn errors of cell death (IECD) with autoinflammatory manifestations could be induced by excessive T cell death. Here the authors characterize IECD patients with autoinflammatory manifestations who possess overactive RIPK1 variants which promote T cell death, secretion of TNF and IFN-γ along with activation of monocytes and macrophages which promotes further autoinflammation.

Robustness checks and reproduction of analyses with existing and updated data based on 110 articles in economics and political science journals with data and code-sharing requirements found high levels of robustness and reproducibility and determined that robustness was not dependent on author characteristics or data availability.

Development of the pangenome-informed genome assembly (PIGA) workflow enabled the generation of 1,116 diploid genome assemblies (55 de novo and 1,061 pangenome-informed), representing an extensive resource of medically relevant genic variations.

Hydrocyclone flow fields enhance H₂ production via shear induced lattice restructuring. Here, the authors report a multiscale framework linking reactor hydrodynamics to nanoscale catalysis, guiding industrial photocatalytic H₂ production.

By analysing genome-wide cfDNA fragmentation, a prospective case-control study develops a machine learning model that sensitively detects early breast cancer, classifies tumour subtypes, and assesses lymph node involvement from a single blood draw

MatterGen is a model that generates stable, diverse inorganic materials across the periodic table and can further be fine-tuned to steer the generation towards a broad range of property constraints.

Low effective doping of boron limits the performance of solar cells based on hydrogenated amorphous silicon. Liu et al. show that light induces the diffusion of hydrogen atoms, which activates boron doping, enabling a power conversion efficiency of over 25%.

Humanity’s Last Exam, a multi-modal benchmark at the frontier of human knowledge, is designed to be an expert-level closed-ended academic benchmark with broad subject coverage.

Experiments in mice and pigs revealed that l-theanine produced by Lactobacillus reuteri acts on host cells to increase the catabolism of branched-chain amino acids by stabilizing the expression of branched-chain amino acid transferases.

Coating additive solutions onto wet perovskite films in situ enables flexible all-perovskite tandem solar cells with a certified power conversion efficiency of 23.0% for a module with an aperture area of 20.26 cm². The modules maintain 97% of their initial efficiency after 10,000 bending cycles with a 10 mm radius.

The authors consider the changing sensitivity of the leaf-onset date to temperature (S_T) for boreal deciduous broadleaf forests. S_T increased between 1982–1996 and 1998–2012—potentially linked to enhanced chilling accumulation—but this increase is underestimated in phenology models.

Influenza B/Yamagata lineage has rarely been detected since COVID-19 non-pharmaceutical interventions were introduced, while transmission of other influenza lineages resumed. Here, the authors investigate reasons for the probable extinction of the B/Yamagata lineage by analysing viral, environmental, and host-related factors.

Solar flow batteries (SFBs) can convert, store and release intermittent solar energy but have been built with complex multi-junction solar cells. Here an efficient and stable SFB is shown with single-junction GaAs solar cells via rational potential match modeling and operating condition optimization.

The authors study the effects of heterovalent doping on superconducting bilayer nickelate thin films.

Zhang and colleagues found that Omicron RBD binding to Siglec-9 impaired phagocytosis and antigen presentation in macrophages, an effect abrogated by an F375S mutation in the spike protein of Omicron.

Extracting high-purity salt from saline water through conventional processes is complex and environmentally unsustainable. A diffusion-driven selective crystallization strategy that uses a precisely designed floating porous membrane to suppress non-ion-selective transfer enables simple and precise ion separation and high-purity salt production from mixed source solutions such as Na⁺/K⁺, Ba²⁺/K⁺ and Mg²⁺/Li⁺.

Infection with SARS-CoV-2 causes interstitial pneumonia and viral replication in the lungs of transgenic mice that express a human version of ACE2, confirming the pathogenicity of the virus in this model.

Light-emitting diodes based on halide perovskites have made remarkable progress but their stability is the bottleneck. Here Miao et al. show 14% quantum efficiency at a current density of 300 mA cm-2 and 23.7 hr lifetime under a current density of 100 mA cm-2, making it promising for actual application.

Semi-metallic single crystals of antimony can be deposited using molecular beam epitaxy on molybdenum disulfide to create ohmic contacts with resistance of under 100 Ω µm at a contact length of 18 nm.

Microglia play a critical role in Alzheimer’s disease progression. Here, the authors show that knockout of microglial Cx43 or inhibition of Cx43 hemichannels by nanoparticle-delivered peptide mitigates cognitive deficits and neuropathology in APP/PS1 mice by inducing microglia into a neuroprotective state.

Abnormal functions of mesenchymal stem cells (MSC) contribute into the pathogenensis of ankylosing spondylitis (AS). Here, the authors show that TNF-α at high concentration induces enhances migration of AS-MSC through METTL14 mediated m6A modification of the ELMO1 3′ UTR.

We integrate polarization-gated UV phototransistor and blue InGaN/GaN mini-LED. The photon-generated electrons in the UV phototransistor make the mini-LED generate blue emission. This makes UV light “visible” to naked eyes.

A versatile hydrothermal approach in an operando acidic environment created ferromagnetic single-atom spin catalysts (SASCs). Ni-based SASC exhibits a giant magnetic field enhancement of OER activity, boosting both water and saline water electrolysis.

Microscale ferroelectric topological textures in freestanding BaTiO₃ nanomembranes enable dynamic vortex light manipulation via nonlinear spin-to-orbit conversion.

Achieving rapid thermal concealment across a wide temperature range is challenging. Here, the authors report a thermoelectric device-based thermal cloak that responds within 2.03 seconds over a temperature range from 5.77 °C to 109.16 °C.

The sterile insect technique involves the introduction of sterile males to induce sterility in females and reduce population size. Here, the authors show that sterile males may also reduce female density and inhibit female blood feeding through mating harassment.

Aqueous solutions that can enter glassy state have excellent anti-freezing property. Here the authors propose a glass-forming liquid by tailoring tetrahedral and pair-correlation entropies to achieve ultralow temperature energy applications.

Alterations in myocardial mitochondrial metabolism following myocardial infarction (MI) lead to structural and functional abnormalities of the heart. Here, the author shows that inhibiting the palmitoylation of CD36 alleviates lipid metabolism disorders and mitochondrial dysfunction in cardiomyocytes post-MI.

Rising global military spending significantly increases CO₂ emission intensity, potentially jeopardizing the 1.5 °C and 2 °C climate targets if military expenditure ratio exceeds critical thresholds.

A controllable magnetoelectric phase based on symmetry engineering is challenge in natural bulk crystals. Here, via engineering of interfacial Dzyaloshinskii-Moriya interaction, the authors design a magnetoelectric phase transition in oxide superlattices of correlated electron systems.

Pityriasis rubra pilaris (PRP) is a chronic immune‐mediated papulosquamous dermatosis and is caused by dysregulation of keratinocytes. Here the authors identify keratin 32 (KRT32) mutations associated with PRP which results in the inhibitory function of KRT32 towards NF-kB signalling and IKK complex formation being reduced.