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We establish operator-enabled holography as a new paradigm, transcending intrinsic physical dimensions of light to achieve high-capacity and high-security multiplexing.

Zinc-bromine flow batteries face challenges from corrosive Br₂, which limits their lifespan and environmental safety. Here, the authors introduce sodium sulfamate as a Br₂ scavenger, enabling a more durable and higher-energy-density Zn/Br flow battery suitable for large-scale operation.

The authors report a large-scale spin-locking effect of light within a Brownian medium arising from the intrinsic spin–orbit interactions of scattering from multiple individual nanoparticles in a complex disordered system.

Autonomous artificial intelligence (AI) models to replace human decision-making in medical intervention need thorough testing. Here authors present the results of a clinical trial, NCT05600855, in which daGOAT, a conditional autonomous artificial intelligence agent successfully makes the decision whether to prescribe an immune suppressive drug to prevent severe acute graft-versus-host disease following HLA-mismatched haematopoietic cell transplantation.

Reversed Cherenkov radiation has not been observed due to the absence of suitable all-metal left-handed materials for beam transport and suitable couplers for extracting the signal. Here, Duanet al. develop a metamaterial to observe reversed Cherenkov radiation using real charged particles.

Photonic quasiparticles are neutral, so controlling them by coupling with external fields is generally impossible. Now, by synthesizing a two-level photonic system, coupling with an electric field becomes possible and enables electrical control.

Artificial gauge fields offer a powerful tool for engineering the topological phase of matter. Here, the authors propose a scheme to simulate an SL\((2,{\mathbb{C}})\) non-Abelian gauge field by coupled photonic molecules in synthetic space-frequency dimensions, which enables various Dirac semimetal transitions.

The quantum fusion of two independent 10-user networks is demonstrated based on multi-user entanglement swapping. Active temporal and wavelength multiplexing schemes are developed to merge the two networks into a larger network with 18 users in the quantum correlation layer.

Deciphering the formation sequence of surface methoxy species (SMS) and dimethyl ether (DME) in zeolite-catalyzed methanol reactions remains a challenge. Here, the authors tackle this issue by employing a microenvironment design strategy to steer reaction pathways within zeolite channels, enabling SMS formation from DME decomposition catalyzed by Brønsted acids at 363 K.

A superposition of tunable photonic lattices is used to create optical moiré patterns and demonstrate the resulting localization of light waves through a mechanism based on flat-band physics.

Tumour cell behaviour is an underdeveloped target for cancer intervention. Here the authors report on a spatiotemporal interaction between tumour cells and osteoclasts in initial bone metastases and propose a behaviour-targeting therapy with an in situ physical killing strategy.

The strong modulation introduces coherent-multiple-transition into discrete time quantum walks in the frequency space, inducing topological band and fast quantum gate operations.

Ionic or molecular transport in conventional polymeric membranes often suffers from a trade-off between permeability and selectivity. The authors report on an interfacial polymer cross-linking strategy to produce a robust, permeable and selective 3-µm-thick ultrathin polymeric membrane containing quasi-ordered reticular cross-linking structures.

Determining the causal variants at GWAS loci is crucial for understanding genetic disease mechanisms. Here, the authors apply MPRA to perform non-small cell lung cancer (NSCLC) variant-to-function mapping at scale and propose distinct genetic architectures underlying NSCLC susceptibility.

The incorporation of foreign objects into cells can be used in various avenues of biological research, although crossing the cell membrane can be challenging. Here, the authors use a diamond nanoneedle array for enhanced delivery of various particles into cells, including neurons.

Proof of concept of the viability of a plant-derived photosynthetic system based on nanothylakoid units encapsulated in a chondrocyte membrane to enhance cell anabolism in chondrocytes is demonstrated.

Exceptional point introduces the ability to control and tune light propagation. Here the authors demonstrate a 90-μm-radius optical microcavity to store light, induced by nonlinear Brillouin scattering at room temperature.

How RNA polymerase II transcription of tandemly repetitive satellite DNAs is regulated is poorly understood. Here, the authors identify Topoisomerase I as an evolutionary key regulator for satellite DNA transcription under both normal and DNA double-stranded break conditions.

Heterotopic ossification (HO) is the formation of pathological mature bone within extraskeletal soft tissues, and there are currently no reliable methods for removing these calcified plaques. Here, the authors demonstrate that chemically engineered osteoclasts coated with tetracycline can improve their targeting capacity to ectopic calcifications, which extends their bone resorption functions for the treatment of HO.

The NetID algorithm annotates untargeted LC-MS metabolomics data by combining known biochemical and metabolomic principles with a global network optimization strategy.

Redox flow batteries are solutions to cost-effective grid-scale energy storage. Here the authors report air-stable naphthalene-based redox-active molecules for scaled-up aqueous flow batteries.

Dual-wavelength emission materials can provide fluorescence intensity ratio technology with self-calibration features; their fabrication however, remains a challenge. Here, authors design a dual-wavelength emitting material Li₂ZnSiO₄:Mn²⁺ and present a wearable optical fibre temperature sensor, functioning in both contact and noncontact modes.

Exciton scattering in perovskite is an important phenomenon dictating the optoelectronic performance. Here, the authors confirm the deformation potential scattering by charged defects, not by the non-polar optical phonons, dominates the excitons interband relaxation in 2D Sn-based perovskites.

The authors proposed a method for simulating non-Abelian Aharonov Bohm interferences with a temporal multilayer structure in the discrete physical system. Such a method for studying non-Abelian physics can be generalized to arbitrary dimensions.

Aerogels have limited application in textiles due to their fragility and poor processability. Here, authors synthesize an ultrathin aerogel-structured micro/nanofiber metafabric for self-sustained heating by developing a dual air-gelation strategy.

Defects in porous materials can alter the pore structure and chemical properties. Here authors demonstrate an approach for studying defects in metal-organic frameworks using ³¹P NMR and probe molecules.

A violation of bilocal inequality is demonstrated with two truly independent light sources delivering entanglements to three nodes. To this end, the locality, measurement independence and quantum source independence loopholes are closed simultaneously.

The Möbius strip exhibits unique topological resonances, which are fundamental for topology-based signal processing. The authors realise a Möbius ring resonator via polarization-maintaining fibers, observing topological resonances emerging from the coupling between the two polarization modes along the fast and slow axes of the ring.

Here the authors present a quantitative proteomics strategy to identify long noncoding RNA (lncRNA)-binding proteins and demonstrate its application by characterizing the lncRNA HULC (highly upregulated in liver cancer), which is shown to interact with glycolytic enzymes and modulate their activity.

Patients with recurrent or metastatic cervical cancer have limited therapeutic options. Here the authors report efficacy and safety of camrelizumab (anti-PD-1 antibody) in combination with famitinib (anti-angiogenic agent) in pre-treated recurrent or metastatic squamous cervical cancer.

Heterogeneous catalysts for olefin hydroformylation are highly desired but suffer from poor activity. Herein, the authors report that rhodium nanoparticles supported on siliceous MFI zeolite with abundant silanol nests are very active for hydroformylation, affording a turnover frequency that outperforms the classical Wilkinson’s catalyst.