Nature Search

The landscape and regulatory potential of eccDNAs in mammalian preimplantation embryos

Extrachromosomal circular DNA (eccDNA) is a regulatory element involved in genomic stability and gene regulation. This study identifies widespread eccDNA in early mammalian embryos. These eccDNAs arise from active genomic regions, increase during a major wave of gene activation, and can regulate key developmental genes.

Ling Wei
Ning Wu
Fengbiao Mao
ResearchOpen Access31 Mar 2026
Nature Communications

P: 1-19
Charting brain morphology in international healthy and neurological populations

Liu et al. report Chinese normative lifespan brain charts showing later neurodevelopmental milestones than those detected in Western cohorts. Individual deviations from these norms are valuable in assessing clinical risk and outcomes.

Zhizheng Zhuo
Li Chai
Yaou Liu
Research29 Dec 2025
Nature Neuroscience

Volume: 29, P: 420-434
A cough sound-based deep learning algorithm for accessible prompt detection of chronic obstructive pulmonary disease with smartphones

Jun Zhou
Jingwen Huang
Jieming Qu
ResearchOpen Access28 Mar 2026
npj Primary Care Respiratory Medicine

Volume: 36, P: 1-9
The first chromosome-level genome of the stag beetle Dorcus hopei Saunders, 1854 (Coleoptera: Lucanidae)

Xiaolu Li
Chuyang Mao
Xueyan Li
ResearchOpen Access18 Apr 2024
Scientific Data

Volume: 11, P: 1-7
Engineering the pore environment of antiparallel stacked covalent organic frameworks for capture of iodine pollutants

Radioiodine capture from nuclear fuel waste and contaminated water sources is of environmental importance but technically challenging. Here, the authors report covalent organic frameworks with antiparallel eclipsed stacked structures with dynamic adsorption performance for iodine pollutants under various conditions.

Yinghui Xie
Qiuyu Rong
Xiangke Wang
ResearchOpen Access26 Mar 2024
Nature Communications

Volume: 15, P: 1-11
Excitatory nucleo-olivary pathway shapes cerebellar outputs for motor control

Complex spikes (CSs) driven by inferior olivary neurons have crucial roles in motor control. Wang et al. identified an excitatory pathway from the cerebellar nuclei to the inferior olive that drives rapid feedback CSs and contributes to the fine control of ocular and body movements.

Xiaolu Wang
Zhiqiang Liu
Zhenyu Gao
ResearchOpen Access20 Jul 2023
Nature Neuroscience

Volume: 26, P: 1394-1406
Sub-minute synthesis and modulation of β/λ-M_xTi_3-xO₅ ceramics towards accessible heat storage

Reversible phase transitions between the β and λ phases of Ti₃O₅ under moderate conditions still remain challenging. Here, the authors report elemental substitution and (001) crystal plane compression strategies to achieve accessible heat storage

Pengfei Zhao
Guangshi Li
Xionggang Lu
ResearchOpen Access11 Mar 2025
Nature Communications

Volume: 16, P: 1-9
Mesoscopic sliding ferroelectricity enabled photovoltaic random access memory for material-level artificial vision system

Intelligent materials change their properties under external stimuli, integrating functionalities at the matter level. Here, Guo et al. report an artificial vision system based on the memory effect produced by sliding ferroelectricity in multiwalled tungsten disulfide nanotubes.

Yan Sun
Shuting Xu
Yao Guo
ResearchOpen Access14 Sept 2022
Nature Communications

Volume: 13, P: 1-8
CaMKII-δ9 promotes cardiomyopathy through disrupting UBE2T-dependent DNA repair

Zhang et al. report the role of CaMKII-δ9, a previously less-studied isoform, in driving cardiomyopathy. Mechanistically, CaMKII-δ9 phosphorylates UBE2T, resulting in its degradation and impairing DNA repair.

Mao Zhang
Hua Gao
Rui-Ping Xiao
Research02 Sept 2019
Nature Cell Biology

Volume: 21, P: 1152-1163
Causal association between blood leukocyte counts and vascular dementia: a two-sample bidirectional Mendelian randomization study

Shufang Liu
Chenwei Zhang
Sijin Li
ResearchOpen Access23 Aug 2024
Scientific Reports

Volume: 14, P: 1-11
Scoring cytokine storm by the levels of MCP-3 and IL-8 accurately distinguished COVID-19 patients with high mortality

Liting Chen
Gaoxiang Wang
Jianfeng Zhou
ResearchOpen Access14 Dec 2020
Signal Transduction and Targeted Therapy

Volume: 5, P: 1-3
TBX6-associated congenital scoliosis (TACS) as a clinically distinguishable subtype of congenital scoliosis: further evidence supporting the compound inheritance and TBX6 gene dosage model

Jiaqi Liu
Nan Wu
Guixing Qiu
Research14 Jan 2019
Genetics in Medicine

Volume: 21, P: 1548-1558
Elevated serum levels of S100A8/A9 and HMGB1 at hospital admission are correlated with inferior clinical outcomes in COVID-19 patients

Liting Chen
Xiaolu Long
Jianfeng Zhou
Correspondence03 Jul 2020
Cellular & Molecular Immunology

Volume: 17, P: 992-994

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The landscape and regulatory potential of eccDNAs in mammalian preimplantation embryos

Charting brain morphology in international healthy and neurological populations

A cough sound-based deep learning algorithm for accessible prompt detection of chronic obstructive pulmonary disease with smartphones

The first chromosome-level genome of the stag beetle Dorcus hopei Saunders, 1854 (Coleoptera: Lucanidae)

Engineering the pore environment of antiparallel stacked covalent organic frameworks for capture of iodine pollutants

Excitatory nucleo-olivary pathway shapes cerebellar outputs for motor control

Sub-minute synthesis and modulation of β/λ-M_xTi_3-xO₅ ceramics towards accessible heat storage

Mesoscopic sliding ferroelectricity enabled photovoltaic random access memory for material-level artificial vision system

CaMKII-δ9 promotes cardiomyopathy through disrupting UBE2T-dependent DNA repair

Causal association between blood leukocyte counts and vascular dementia: a two-sample bidirectional Mendelian randomization study

Scoring cytokine storm by the levels of MCP-3 and IL-8 accurately distinguished COVID-19 patients with high mortality

TBX6-associated congenital scoliosis (TACS) as a clinically distinguishable subtype of congenital scoliosis: further evidence supporting the compound inheritance and TBX6 gene dosage model

Elevated serum levels of S100A8/A9 and HMGB1 at hospital admission are correlated with inferior clinical outcomes in COVID-19 patients

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