Nature Search

Trans-ancestry genome-wide analyses of bipolar disorder in East Asian and European populations improve genetic discovery

The authors conducted a genome-wide association study of bipolar disorder (BD) in Han Chinese and integrated PGC4 East Asian and European datasets, discovering 23 novel loci, prioritizing 39 credible risk genes and implicating BD-related cell types and druggable targets.

Chu-Yi Zhang
Miao Li
Ming Li
Research25 Nov 2025
Nature Neuroscience

P: 1-13
A moonlighting function of tumoral interleukin-1β precursor promotes metastasis via RACK1-mediated actin remodeling

Interleukin-1β (IL-1β) is a proinflammatory factor related to cancer progression that is synthesized as a precursor named pro-interleukin-1β (Pro-IL-1β). Here, the authors discover that Pro-IL-1β presents a IL-1β-independent pro-metastatic function through RACK1 regulation and modulation of actin cytoskeleton remodeling.

Quanzhu Chen
Pan Wu
Bo Xiang
ResearchOpen Access19 Nov 2025
Nature Communications

Volume: 16, P: 1-19
Direct transfer of tri- and di-fluoroethanol units enabled by radical activation of organosilicon reagents

Methods for direct incorporation of tri- and di-fluoroethanol units in molecules are relatively limited. Here, the authors report two organosilicon reagents which are applied to allylation, alkylation and alkenylation reactions as tri- and di-fluoroethanol transfer reagents.

Xiang Chen
Xingxing Gong
Xiao Shen
ResearchOpen Access02 Jun 2020
Nature Communications

Volume: 11, P: 1-9
Telemedicine-based integrated management of atrial fibrillation in village clinics: a cluster randomized trial

A cluster randomized trial in China shows that telemedicine-based, village doctor-led delivery of integrated care reduced the occurrence of adverse cardiovascular events and hospitalizations in older adults with atrial fibrillation.

Ming Chu
Shimeng Zhang
Shanshan Lu
Research21 Feb 2025
Nature Medicine

Volume: 31, P: 1276-1285
Direct observation of single-molecule hydrogen-bond dynamics with single-bond resolution

Hydrogen-bonds are widely found in many systems, such as DNAs and supramolecular assemblies, but it remains challenging to detect their dynamics at a molecular level. Here, Zhou et al. study the stochastic arrangement of hydrogen bonds using single-molecule junctions connected to graphene electrodes.

Ce Zhou
Xingxing Li
Xuefeng Guo
ResearchOpen Access23 Feb 2018
Nature Communications

Volume: 9, P: 1-9
USP8 maintains embryonic stem cell stemness via deubiquitination of EPG5

Autophagy is implicated in self-renewal of stem cells, including embryonic stem cells (ES cells). Here the authors demonstrate EPG5 is highly expressed in ES cells, and its deubiquitylation by USP8 stimulates its interaction with LC3 to promote autophagy and maintenance of stemness.

Haifeng Gu
Xingxing Shi
Tongbiao Zhao
ResearchOpen Access01 Apr 2019
Nature Communications

Volume: 10, P: 1-9
Gene-level analysis reveals the genetic aetiology and therapeutic targets of schizophrenia

Luo et al. identify schizophrenia risk loci in East Asians and uncover potential causal genes and therapeutic targets through cross-ancestry GWAS, fine mapping and functional genomics, offering insights into the genetic basis of schizophrenia.

Xinglun Dang
Zhaowei Teng
Xiong-Jian Luo
Research03 Jan 2025
Nature Human Behaviour

Volume: 9, P: 609-624
Genomic analyses of rice bean landraces reveal adaptation and yield related loci to accelerate breeding

Rice bean is an underexploited legume crop that has many desirable properties against bio and abiotic stresses. Here, the authors report the genome assembly of this species, conduct population genetics studies and reveal the genetic variations associated with adaptation and yield traits.

Jiantao Guan
Jintao Zhang
Lixia Wang
ResearchOpen Access29 Sept 2022
Nature Communications

Volume: 13, P: 1-16
Thermal migration towards constructing W-W dual-sites for boosted alkaline hydrogen evolution reaction

While platinum is a highly active catalyst for H₂ evolution, its low abundance prompts research into earth-abundant alternatives. Here, authors prepare tungsten atomic clusters on phosphorus doped carbon by thermal migration and demonstrate excellent activities for hydrogen evolution electrocatalysis.

Zhigang Chen
Yafeng Xu
Yi Cui
ResearchOpen Access09 Feb 2022
Nature Communications

Volume: 13, P: 1-12
Gold nanoparticle transfer through photothermal effects in a metamaterial absorber by nanosecond laser

Hanmo Gong
Yuanqing Yang
Min Qiu
ResearchOpen Access26 Aug 2014
Scientific Reports

Volume: 4, P: 1-4
Negative linear compressibility in a crystal of α-BiB₃O₆

Lei Kang
Xingxing Jiang
Zheshuai Lin
ResearchOpen Access25 Aug 2015
Scientific Reports

Volume: 5, P: 1-7
Macrophage miR-4524a-5p/TBP promotes β-TrCP -TIM3 complex activation and TGFβ release and aggravates NAFLD-associated fibrosis

Chunming Li
Lei Fang
Chuan-Ming Xie
ResearchOpen Access19 Apr 2025
Cell Death & Disease

Volume: 16, P: 1-13
Exploring the ceRNA network involving AGAP2-AS1 as a novel biomarker for preeclampsia

Fan Lu
Ni Zeng
Houkang Lei
ResearchOpen Access09 Nov 2024
Scientific Reports

Volume: 14, P: 1-16
Portable DNA extraction integrated with LAMP-CRISPR/Cas12a technology for on-site detection of Salmonella Typhimurium

Liang Zhang
Mengfan Zhang
Xiuling Song
ResearchOpen Access24 Mar 2025
npj Science of Food

Volume: 9, P: 1-11

Search

Trans-ancestry genome-wide analyses of bipolar disorder in East Asian and European populations improve genetic discovery

A moonlighting function of tumoral interleukin-1β precursor promotes metastasis via RACK1-mediated actin remodeling

Direct transfer of tri- and di-fluoroethanol units enabled by radical activation of organosilicon reagents

Telemedicine-based integrated management of atrial fibrillation in village clinics: a cluster randomized trial

Direct observation of single-molecule hydrogen-bond dynamics with single-bond resolution

USP8 maintains embryonic stem cell stemness via deubiquitination of EPG5

Gene-level analysis reveals the genetic aetiology and therapeutic targets of schizophrenia

Genomic analyses of rice bean landraces reveal adaptation and yield related loci to accelerate breeding

Thermal migration towards constructing W-W dual-sites for boosted alkaline hydrogen evolution reaction

Gold nanoparticle transfer through photothermal effects in a metamaterial absorber by nanosecond laser

Negative linear compressibility in a crystal of α-BiB₃O₆

Macrophage miR-4524a-5p/TBP promotes β-TrCP -TIM3 complex activation and TGFβ release and aggravates NAFLD-associated fibrosis

Exploring the ceRNA network involving AGAP2-AS1 as a novel biomarker for preeclampsia

Portable DNA extraction integrated with LAMP-CRISPR/Cas12a technology for on-site detection of Salmonella Typhimurium

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