By assembling into ‘virion vesicles’, the H129 strain of herpes simplex virus-1 hijacks synaptic machinery for its anterograde spread, co-opting voltage-gated Ca2+ channels, Syt7 and SNAREs for presynaptic exit, then nectin-1/CME for postsynaptic entry.
- Hai-Bin Qin
- Yue-Peng Zhou
- Min-Hua Luo