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Scientific Reports (19)
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Showing 1–50 of 65 results

Advanced filters: Author: Yingxin Liu Clear advanced filters

Central amygdala single-nucleus atlas reveals chromatin and gene transcription dynamics in human alcohol use disorder

The study used snMultiome-seq to map gene expression and chromatin accessibility in human central amygdala cells from people with and without AUD. Here, the authors show that inhibitory neurons are most affected, with KLF16-driven regulatory changes and AUD-risk variants disrupting gene activity.

Che Yu Lee
Ahyeon Hwang
Matthew J. Girgenti
ResearchOpen Access19 Jan 2026
Nature Communications

P: 1-17
VISTA uncovers missing gene expression and spatial-induced information for spatial transcriptomic data analysis

VISTA is a scalable, uncertainty-aware model that imputes missing genes in spatial transcriptomics by integrating scRNA-seq and spatial data. It improves accuracy, enables discovery of spatial patterns, CCIs, RNA velocity, and supports perturbation transfer.

Tianyu Liu
Yingxin Lin
Hongyu Zhao
ResearchOpen Access08 Jan 2026
Communications Biology

P: 1-16
UNICORN: Towards universal cellular expression prediction with a multi-task learning framework

Here, authors present UNICORN, a multi-task learning framework that integrates foundation model embeddings and multi-omic data to accurately predict cell-type-specific gene expression and uncover biological insights.

Tianyu Liu
Tinglin Huang
Hongyu Zhao
ResearchOpen Access27 Oct 2025
Nature Communications

Volume: 16, P: 1-14
Transferrin-phosphatidylserine liposomes target TDP-43 and neuroinflammation in male mice with neuropathic pain

Neuropathic pain is driven by chronic neuroinflammation involving dysfunction of microglia and astrocytes. Here, the authors develop nanoparticles that block TDP-43 aggregation and suppress glial activation via the cGAS-STING pathway in a mouse model, highlighting a promising therapeutic strategy.

Yingxin Liu
Yue Wu
Jiamin Miao
ResearchOpen Access12 Dec 2025
Nature Communications

Volume: 16, P: 1-20
Spatial dynamics of brain development and neuroinflammation

A tri-omic atlas of the mouse brain from postnatal day 0 to P21 reveals that layer-specific projection neurons have a role in coordinating axonogenesis and myelination.

Di Zhang
Leslie A. Rubio Rodríguez-Kirby
Rong Fan
ResearchOpen Access05 Nov 2025
Nature

Volume: 647, P: 213-227
Neuronal diversity and stereotypy at multiple scales through whole brain morphometry

Here the authors analyzed 3.7 petavoxels of 3D imaging data from 204 mouse brains, aiming to comprehensively characterize diverse morphological and modular patterns conserved across six spatial scales of mouse brain anatomy, ranging from the whole-brain scale to synaptic levels.

Yufeng Liu
Shengdian Jiang
Hanchuan Peng
ResearchOpen Access26 Nov 2024
Nature Communications

Volume: 15, P: 1-23
Global impoverishment of natural vegetation revealed by dark diversity

A comparison of alpha diversity (number of plant species) and dark diversity (species that are currently absent from a site despite being ecologically suitable) demonstrates the negative effects of regional-scale anthropogenic activity on plant diversity.

Meelis Pärtel
Riin Tamme
Martin Zobel
ResearchOpen Access02 Apr 2025
Nature

Volume: 641, P: 917-924
Atlas-scale single-cell multi-sample multi-condition data integration using scMerge2

Recent advances in multi-condition single-cell multi-cohort studies enable exploration of diverse cell states. Here, authors present scMerge2, an algorithm that allows integration of a large COVID-19 data collection with over five million cells to uncover distinct signatures of disease progression.

Yingxin Lin
Yue Cao
Jean Y. H. Yang
ResearchOpen Access17 Jul 2023
Nature Communications

Volume: 14, P: 1-13
Development and validation of a predictive model for 90-day mortality risk after discharge in patients with cirrhosis and esophagogastric variceal bleeding

Yingxin Zeng
Xinmei Zhang
Guodong Xia
ResearchOpen Access14 Aug 2025
Scientific Reports

Volume: 15, P: 1-9
Post-translational toxin modification by lactate controls Staphylococcus aureus virulence

The potential roles of post-translational modification of bacterial proteins in pathogenesis are not well understood. Here, Wang et al. show that posttranslational lactylation of proteins, in particular alpha-toxin, is important for virulence of the human pathogen Staphylococcus aureus.

Yanan Wang
Yanfeng Liu
Min Li
ResearchOpen Access13 Nov 2024
Nature Communications

Volume: 15, P: 1-13
Enhanced kernel search optimizer with sand cat behavior and multi-strategy fusion for economic emission dispatch

Ruyi Dong
Yingxin Tang
Huiling Chen
ResearchOpen Access18 Nov 2025
Scientific Reports

Volume: 15, P: 1-30
A CD26⁺ tendon stem progenitor cell population contributes to tendon repair and heterotopic ossification

Chen, et al identify peritendon CD26 expressing tendon stem/progenitor cells that contribute to tendon healing, as well as Tenascin-C/YAP dependent heterotopic ossification.

Siwen Chen
Yingxin Lin
Hui Liu
ResearchOpen Access16 Jan 2025
Nature Communications

Volume: 16, P: 1-18
Racial and ethnic differences in controlling risk factors for cardiovascular disease among adults with obesity, 1999–2023

Yingxin Liu
Changfa Zhang
Guowei Li
Research23 Dec 2025
International Journal of Obesity

P: 1-8
Live cell imaging of single genomic loci with quantum dot-labeled TALEs

Visualizing single genomic loci in living cells remains technically challenging. Here the authors adopt a strategy of labelling a pair of transcription activator-like effectors (TALEs) with differently coloured quantum dots and use them to identify integrated HIV-1 proviral DNA sequences in living cells.

Yingxin Ma
Mingxiu Wang
Zongqiang Cui
ResearchOpen Access08 May 2017
Nature Communications

Volume: 8, P: 1-8
scMODAL: a general deep learning framework for comprehensive single-cell multi-omics data alignment with feature links

Single-cell multi-omics integration is challenged by varied feature relationships and modality-specific limitations. Here, the authors present scMODAL, a deep learning framework that leverages known feature links to align single-cell omics, enabling accurate integration and downstream analyses.

Gefei Wang
Jia Zhao
Hongyu Zhao
ResearchOpen Access29 May 2025
Nature Communications

Volume: 16, P: 1-13
PA28γ-containing tumor-derived exosomes promote T-cell dysfunction in head and neck squamous cell carcinoma

Ying Wang
Shiyu Zhang
Jing Li
Research08 Dec 2025
Cellular & Molecular Immunology

Volume: 23, P: 63-78
STV11 encodes a sulphotransferase and confers durable resistance to rice stripe virus

Rice stripe virus (RSV) causes a disease in rice with significant economic consequences. Here, the authors clone an RSV-resistant gene in rice and suggest that this gene encodes a sulphotransferase that catalyses the conversion of salicylic acid (SA) into sulphonated salicylic acid, leading to increased SA accumulation in RSV-infected plants and inhibition of viral replication.

Qi Wang
Yuqiang Liu
Jianmin Wan
ResearchOpen Access09 Sept 2014
Nature Communications

Volume: 5, P: 1-8
UFL1-mediated UFMylation antagonizes IFT88 ubiquitination and degradation to maintain ciliary homeostasis

Runa Wang
Guizhi Guo
Jie Ran
Research21 Nov 2025
Cell Death & Differentiation

P: 1-16
Ubiquitous short-range order in multi-principal element alloys

Chemical short-range order (CSRO) has been explored as a new design parameter for tuning the performance of multi-principal element alloys (MPEAs), yet its formation kinetics remains unclear. Here the authors demonstrate that significant CSRO forms during solidification, making it ubiquitous in many MPEAs.

Ying Han
Hangman Chen
Yang Yang
ResearchOpen Access01 Aug 2024
Nature Communications

Volume: 15, P: 1-13
Transformable 3D curved high-density liquid metal coils – an integrated unit for general soft actuation, sensing and communication

Developing flexible coils for soft robotic applications is challenging due to their sparse structure. Here, the authors present a design of transformable 3D curved high-density liquid metal coils, surpassing the structural density level of enameled wire for soft actuation, sensing, and communication.

Nan Li
Yingxin Zhou
Jing Liu
ResearchOpen Access05 Sept 2024
Nature Communications

Volume: 15, P: 1-13
Limits on the luminance of dark matter from xenon recoil data

A direct search for effective electromagnetic interactions between dark matter and xenon nuclei that produce a recoil of the latter is carried out and the first constraint on charge radius of dark matter is derived.

Xuyang Ning
Abdusalam Abdukerim
Yubo Zhou
Research17 May 2023
Nature

Volume: 618, P: 47-50
Production of diacetyl by metabolically engineered Enterobacter cloacae

Lijie Zhang
Yingxin Zhang
Cuiqing Ma
ResearchOpen Access12 Mar 2015
Scientific Reports

Volume: 5, P: 1-7
Genome of a novel Fangshan bunya-like virus identified in mosquitoes from Shandong Province, China

Yuli Zhang
Yujie Liu
Yujing Zhu
ResearchOpen Access26 Aug 2025
Scientific Reports

Volume: 15, P: 1-13
Publication of data sharing statements in clinical trials by cardiovascular journals: a quantitative and qualitative analysis

Yingxin Liu
Gregory Y. H. Lip
Guowei Li
ResearchOpen Access15 Jul 2025
Scientific Data

Volume: 12, P: 1-10
Fractionation of Stable Cadmium Isotopes in the Cadmium Tolerant Ricinus communis and Hyperaccumulator Solanum nigrum

Rongfei Wei
Qingjun Guo
Yingxin Wan
ResearchOpen Access14 Apr 2016
Scientific Reports

Volume: 6, P: 1-9
Graphene-supported Pd catalyst for highly selective hydrogenation of resorcinol to 1, 3-cyclohexanedione through giant π-conjugate interactions

Zuojun Wei
Ruofei Pan
Yingxin Liu
ResearchOpen Access23 Oct 2015
Scientific Reports

Volume: 5, P: 1-9
A upconversion luminescene biosensor based on dual-signal amplification for the detection of short DNA species of c-erbB-2 oncogene

Jianming Lan
Yingxin Liu
Jinghua Chen
ResearchOpen Access21 Apr 2016
Scientific Reports

Volume: 6, P: 1-8
CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer’s disease

CSF MTBR-tau243 is more related to tau tangles and clinical cognitive impairment in Alzheimer’s disease than phospho-tau biomarkers, which are more related to amyloid plaques.

Kanta Horie
Gemma Salvadó
Randall J. Bateman
ResearchOpen Access13 Jul 2023
Nature Medicine

Volume: 29, P: 1954-1963
Radiation-induced segregation in a ceramic

Radiation-induced segregation is widely observed in metals. Here it is discovered that radiation-induced segregation also occurs in a ceramic, with carbon atoms in silicon carbide segregating to the grain boundaries under irradiation.

Xing Wang
Hongliang Zhang
Izabela Szlufarska
Research25 May 2020
Nature Materials

Volume: 19, P: 992-998
HEFMI-ICH: a hybrid EEG-fNIRS motor imagery dataset for brain-computer interface in intracerebral hemorrhage

Jian Shi
Danyang Chen
Zhouping Tang
ResearchOpen Access18 Nov 2025
Scientific Data

Volume: 12, P: 1-15
Tibetan sheep grazing modifies rodent density and their interactions effect on GHG emissions of alpine meadow

Yingxin Wang
Hang Yuan
Fujiang Hou
ResearchOpen Access19 Nov 2019
Scientific Reports

Volume: 9, P: 1-12
Covariation of scleral remodeling and PI3K/Akt signaling pathway in experimental myopia

Xiaomeng Li
Xiaojing Liu
Hongsheng Bi
ResearchOpen Access11 Apr 2025
Scientific Reports

Volume: 15, P: 1-15
Excessive variability in systolic blood pressure that is self-measured at home exacerbates the progression of brain white matter lesions and cognitive impairment in the oldest old

Zhendong Liu
Yingxin Zhao
Guosheng Jiang
Research03 Dec 2015
Hypertension Research

Volume: 39, P: 245-253
Phenolic compounds induce ferroptosis-like death by promoting hydroxyl radical generation in the Fenton reaction

Development of phenol-tolerant E. coli strains via adaptive evolution provides insight into the molecular mechanism of phenol toxicity and highlights the potential of phloroglucinol-induced ferroptosis-like cell death in cancer biology.

Xinyue Sui
Jichao Wang
Guang Zhao
ResearchOpen Access17 Feb 2024
Communications Biology

Volume: 7, P: 1-12
NCAPH, ubiquitinated by TRIM21, promotes cell proliferation by inhibiting autophagy of cervical cancer through AKT/mTOR dependent signaling

Shiqi Wang
Xiaowen Qiao
Xiao Wang
ResearchOpen Access06 Aug 2024
Cell Death & Disease

Volume: 15, P: 1-16
Ferritin-mediated mitochondrial iron homeostasis is essential for the survival of hematopoietic stem cells and leukemic stem cells

Weiwei Yi
Jinhua Zhang
Zhiyang Chen
Research24 Feb 2024
Leukemia

Volume: 38, P: 1003-1018
Structural mechanism of cooperative activation of the human calcium-sensing receptor by Ca²⁺ ions and L-tryptophan

Shenglong Ling
Pan Shi
Changlin Tian
ResearchOpen Access18 Feb 2021
Cell Research

Volume: 31, P: 383-394
A Multi-Scale Neuron Morphometry Dataset from Peta-voxel Mouse Whole-Brain Images

Shengdian Jiang
Sujun Zhao
Hanchuan Peng
ResearchOpen Access23 Apr 2025
Scientific Data

Volume: 12, P: 1-13
Association between body mass index and semen quality: a systematic review and meta-analysis

Yingxin Li
Yi Lin
Yuewei Liu
Reviews13 Jul 2024
International Journal of Obesity

Volume: 48, P: 1383-1401
Author Correction: HIV-1 Transmissions Among Recently Infected Individuals in Southwest China are Predominantly Derived from Circulating Local Strains

Jianjun Li
Yi Feng
Yiming Shao
Amendments and CorrectionsOpen Access27 Nov 2018
Scientific Reports

Volume: 8, P: 1-2
Longitudinal association of carotid endothelial shear stress with renal function decline in aging adults with normal renal function: A population-based cohort study

Yingxin Zhao
Yuanli Dong
Zhendong Liu
ResearchOpen Access14 Feb 2019
Scientific Reports

Volume: 9, P: 1-11
Nosocomial transmission of Clostridium difficile Genotype ST81 in a General Teaching Hospital in China traced by whole genome sequencing

Juanxiu Qin
Yingxin Dai
Min Li
ResearchOpen Access29 Aug 2017
Scientific Reports

Volume: 7, P: 1-10
Virulence determinants associated with the Asian community-associated methicillin-resistant Staphylococcus aureus lineage ST59

Min Li
Yingxin Dai
Michael Otto
ResearchOpen Access14 Jun 2016
Scientific Reports

Volume: 6, P: 1-13
Genetic dissection of yield traits in super hybrid rice Xieyou9308 using both unconditional and conditional genome-wide association mapping

Yingxin Zhang
Liyuan Zhou
Liyong Cao
ResearchOpen Access11 Apr 2017
Scientific Reports

Volume: 7, P: 1-10
Coordination of carbon and nitrogen accumulation and translocation of winter wheat plant to improve grain yield and processing quality

Xin Huang
Chenyang Wang
Dongyun Ma
ResearchOpen Access25 Jun 2020
Scientific Reports

Volume: 10, P: 1-11
Differential gene expression analysis of ‘Chili’ (Pyrus bretschneideri) fruit pericarp with two types of bagging treatments

Yuling Wang
Xinfu Zhang
Shaolan Yang
ResearchOpen Access08 Mar 2017
Horticulture Research

Volume: 4, P: 1-10
HIV-1 Transmissions Among Recently Infected Individuals in Southwest China are Predominantly Derived from Circulating Local Strains

Jianjun Li
Yi Feng
Yiming Shao
ResearchOpen Access27 Aug 2018
Scientific Reports

Volume: 8, P: 1-9
A national-scale data set for dissolved carbon and its spatial pattern in lakes and reservoirs across China

Zhidan Wen
Kaishan Song
Jia Du
ResearchOpen Access09 Mar 2020
Scientific Data

Volume: 7, P: 1-10
Relationship between metabolic status, physical activity and cardiovascular disease in participants with obesity

Yingxin Liu
Ai Zhao
Guowei Li
Research22 Jan 2024
International Journal of Obesity

Volume: 48, P: 788-795
Prevalence of prehypertension and hypertension in a Chinese rural area from 1991 to 2007

Jianmin Yang
Fanghong Lu
Yun Zhang
Research22 Jan 2010
Hypertension Research

Volume: 33, P: 331-337

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