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Identifying jets originating from heavy quarks plays a fundamental role in hadronic collider experiments. In this work, the ATLAS Collaboration describes and tests a transformer-based neural network architecture for jet flavour tagging based on low-level input and physics-inspired constraints.

Pyramidal neuron-driven mechanisms actively promote the survival and terminal differentiation of their associated interneuron subtypes.

This work proposes a wet-chemical etching assisted aberration-enhanced single-pulsed femtosecond laser nanolithography, named “WEALTH”, for manufacturing small-size, large-area, deep holey nanostructures, promising for emerging nanophotonic devices.

A new artificial intelligence model, DeepSeek-R1, is introduced, demonstrating that the reasoning abilities of large language models can be incentivized through pure reinforcement learning, removing the need for human-annotated demonstrations.

Whilst neutron scattering is a powerful tool for studying spin fluctuations in materials, its availability is limited to large-scale user facilities. Here, the authors demonstrate how the pumping of pure spin currents can be used as a desktop probe to detect an antiferromagnetic transition.

Thermal lepton pairs are ideal probes for the temperature of quark-gluon plasma. Here, the STAR Collaboration uses thermal electron-positron pair production to measure quark-gluon plasma average temperature at different stages of the evolution.

Frustrated magnetic materials attract significant interest because their properties can become dominated by quantum fluctuations. Here the authors show that excitations in the plateau phase of a quantum magnet can be understood semiclassically even though the ground state involves strong quantum effects.

Artificial intelligence-based detection of gastric cancer at different stages from noncontrast computed tomography is suggested to be feasible in a retrospective analysis of large and diverse cohorts, including real-world populations in opportunistic and targeted screening scenarios.

Atomically dispersed catalysts show promising activity for electrochemical reactions but often suffer from limited stability. Here, the authors report an atom-ordering strategy that forms triangular Co sites to activate the substrate for durable alkaline hydrogen production.

The exploitation of the properties of graphene, such as mechanical strength and electrical conductivity, in deformable macroscopic materials is desirable. Here, a combination of graphene chemistry and ice physics is used to fabricate biomimetic, ultralight and superelastic graphene cellular monoliths.

Skyrmions—vortex-like spin textures—are conventionally only seen in materials that exhibit the right magnetic properties. Li et al.now create so-called artificial skyrmions using a cobalt disk embedded in a magnetized nickel film, thus presenting a platform for controlling skyrmions.

The origin of superconductivity enhancement in FeSe monolayer grown on SrTiO₃ compared to bulk FeSe is still a debated issue. Here, Shi et al. report a further 15 K jump of T_c accompanying a second Lifshitz transition triggered by electron doping in FeSe/SrTiO₃monolayer films.

MRI data from more than 100 studies have been aggregated to yield new insights about brain development and ageing, and create an interactive open resource for comparison of brain structures throughout the human lifespan, including those associated with neurological and psychiatric disorders.

Entanglement was observed in top–antitop quark events by the ATLAS experiment produced at the Large Hadron Collider at CERN using a proton–proton collision dataset with a centre-of-mass energy of √s  = 13 TeV and an integrated luminosity of 140 fb⁻¹.

Microporous hydrogels have potential in 3D tissue culture, but precise control over pore formation is challenging. Here, the authors report the use of photopolymerization-induced phase separation to prepare hydrogels suitable for 3D cell culture and bioprinting.

Magnetic domain walls can exhibit a variety of different spin textures. Chen et al. show that it is possible to switch these textures between left handed, right handed, cycloidal, helical and mixed domain wall structures by controlling uniaxial strain in iron/nickel bilayer thin films on tungsten.

While Bell inequalities have been violated several times—mostly in photonic systems—their violations within particle physics experiments are less explored. Here, the BESIII Collaboration showcases Bell-violating nonlocal correlations between entangled hyperon pairs.

Filamin C is a key actin-binding protein involved in cardiomyopathies and musculoskeletal disorders. Here, Wang et al reveal that it interacts with the heat shock protein HSPB7 under biomechanical stress, forming a stable hetero-dimer which is regulated by phosphorylation.

Congenital heart disease is life threatening, and its screening is complex and costly. Here, authors use AI to detect the disease based on pediatric electrocardiogram, suggesting superior performance over cardiologists.

Researchers show inhibiting immune cell steroidogenesis enhances anti-tumour immunity in triple-negative breast cancer. Posaconazole showed promise in a humanised mouse model.

The semileptonic decay channels of the Λc baryon can give important insights into weak interaction, but decay into a neutron, positron and electron neutrino has not been reported so far, due to difficulties in the final products’ identification. Here, the BESIII Collaboration reports its observation in e+e- collision data, exploiting machine-learning-based identification techniques.

Coherent radio emission with a long (nearly 6.5 h) period has been detected from both magnetic poles of a rotating compact object, offering insights into the evolution and emission mechanism of compact radio transients.

Investigating the inner structure of baryons is important to further our understanding of the strong interaction. Here, the BESIII Collaboration extracts the absolute value of the ratio of the electric to magnetic form factors and its relative phase for e + e − → J/ψ → ΛΣ decays, enhancing the signal thanks to the vacuum polarisation effect at the J/ψ peak.

Sun et al. report human lifespan changes in the brain’s functional connectome in 33,250 individuals, which highlights critical growth milestones and distinct maturation patterns and offers a normative reference for development, aging and diseases.

Gas-evolving catalysts suffer from severe mass transport limitations under industrial conditions. Here, the authors report an interfacial metal-layer engineering strategy to separate bubble nucleation from active sites, enabling transfer-resistance-free electrocatalytic interfaces.

The mechanism underpinning the frequency mismatch between THz magnons and the GHz spin currents observed in antiferromagnetic insulators remains unknown. Here, the authors demonstrate that, in a Py/Ag/CoO/Ag/Fe₇₅Co₂₅/MgO(001) heterostructure, a GHz spin current transmits coherently across the antiferromagnetic CoO insulating layer to drive a coherent spin precession of the ferromagnetic Fe₇₅Co₂₅ layer.

Alcohols are more naturally abundant than carbonyl compounds, which in turn are well known for their reactivity in Grignard reactions. Here, the authors showcase a distinct Grignard-like reactivity by using alcohols as coupling partners with hydrazones and synthesize more complex alcohols under ruthenium catalysis.

Ten years after the discovery of the Higgs boson, the ATLAS  experiment at CERN probes its kinematic properties with a significantly larger dataset from 2015–2018 and provides further insights on its interaction with other known particles.

The authors use scanning tunnelling microscopy and spectroscopy to visualize the electronic structure of mirror twin boundaries, revealing a Tomonaga–Luttinger liquid.

Acetylation of the histone variant H2A.Z at gene promoters is associated with oncogene activation; however, it is unclear if such modification has a role in regulating the function of enhancers. Here the authors show that acetylated H2A.Z is redistributed at cancer neo-enhancers and regulates the activity of specific enhancers of cancer-related genes.

Using spin-entangled baryon–antibaryon pairs, the BESIII Collaboration reports on high-precision measurements of potential charge conjugation and parity (CP)-symmetry-violating effects in hadrons.

Here, the genome sequence of the tiger tail seahorse is reported and comparative genomic analyses with other ray-finned fishes are used to explore the genetic basis of the unique morphology and reproductive system of the seahorse.

Measurements of the inelastic cross section of anti-³He allow the estimation of the transparency of the Milky Way to the propagation of these light antinuclei produced in either cosmic-ray collisions or annihilation of dark-matter particles.

Optical trapping is a versatile tool for biomedical applications. Here, the authors use an optofluidic lattice to achieve controllable multi-particle hopping and demonstrate single-bacteria-level screening and measurement of binding efficiency of biological binding agents through particle-enabled bacteria hopping.

A meron is one half of a skyrmion but whether a single meron pair can be created and stabilized remains a challenging question. Here, Gao et al. develop a method to create and stabilize individual pairs of merons in a continuous Py film by local vortex imprinting from Co disks.

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

At the Relativistic Heavy Ion Collider, observations of two meson species produced by heavy-ion collisions, ϕ and K^*0, show surprising patterns of global spin alignment, being unexpectedly large and consistent with zero, respectively.

An antimatter hypernucleus formed by an anti-lambda hadron, an antiproton and two antineutrons was observed through its two-body decay after production in ultrarelativistic heavy-ion collisions.

Voltage fade is a major obstacle for the efficient use of lithium-rich layered oxide materials in batteries. Here, the authors reveal the link between voltage fade and nucleation of a mobile dislocation network in the oxide nanoparticles, offering design ideas to restore the voltage.

The direct measurement of the QCD dead cone in charm quark fragmentation is reported, using iterative declustering of jets tagged with a fully reconstructed charmed hadron.

Mn3Sn is an anti-ferromagnetic material which displays a large magneto-optical Kerr effect, despite lacking a ferromagnetic moment. Here, the authors show that likewise, Mn3Sn, also presents a particularly large magneto-optical Voigt signal, with a negligible change in the quench time over a wide temperature range.

The collective-flow-assisted nuclear shape-imaging method images the nuclear global shape by colliding them at ultrarelativistic speeds and analysing the collective response of outgoing debris.

A deep learning model provides high accuracy in detecting pancreatic lesions in multicenter data, outperforming radiology specialists.