Nature Search

mTOR-driven integrin β4-enriched extracellular vesicles from lenvatinib-resistant hepatocellular carcinoma fuel lung metastasis via fibroblast-niche formation

Tiantian Zou
Xufeng Wang
Lun-Xiu Qin
ResearchOpen Access16 Apr 2026
Signal Transduction and Targeted Therapy

Volume: 11, P: 1-16
In situ observation of mass ejections caused by magnetic reconnections in the ionosphere of Mars

In situ observations reveal explosive mass ejections due to magnetic reconnection in the ionosphere of Mars, with a density cavity as direct evidence. Reconnection between strong open crustal fields can rapidly eject a large amount of mass from Mars.

Yudong Ye
Xiaojun Xu
Zilu Zhou
ResearchOpen Access22 Apr 2024
Nature Astronomy

Volume: 8, P: 838-845
Hopping transport through defect-induced localized states in molybdenum disulphide

There is great interest in molybdenum disulphide for electronic devices but the mechanism of charge transport remains elusive. Qiu et al. find that sulphur vacancies introduce localized donor states within the bandgap, enabling low-carrier-density transport via hopping.

Hao Qiu
Tao Xu
Xinran Wang
Research23 Oct 2013
Nature Communications

Volume: 4, P: 1-6
Field-free switching of a perpendicular magnetic tunnel junction through the interplay of spin–orbit and spin-transfer torques

The interplay between spin–orbit and spin-transfer torques can be used to develop a low-power route to magnetization switching of perpendicular magnetic tunnel junctions without an external magnetic field.

Mengxing Wang
Wenlong Cai
Weisheng Zhao
Research12 Nov 2018
Nature Electronics

Volume: 1, P: 582-588
Real–time digital prescriptions unlock influenza dynamics: evidence from 21 million transactions

Rui Shen
Xueying Xu
Luzhao Feng
ResearchOpen Access04 Mar 2026
npj Digital Medicine

Volume: 9, P: 1-10
Virus-human chromatin interactions reorganise 3D genome and hijack KDM5B for promoting metastasis in nasopharyngeal carcinoma

Epstein–Barr virus - host chromatin interactions in nasopharyngeal carcinoma remain poorly understood. Here, the authors characterise the virus‒host chromatin interactions leading to genome reorganisation and identify a KDM5B-relevant signature associated with distant metastasis.

Dittman Lai-Shun Chung
Zhaozheng Hou
Wei Dai
ResearchOpen Access04 Aug 2025
Nature Communications

Volume: 16, P: 1-21
Intrinsic magnetic topological insulator phases in the Sb doped MnBi₂Te₄ bulks and thin flakes

Available intrinsic magnetic topological insulators are rare. Here, the authors study the electronic and magnetic properties of Mn(Sb_xBi_(1-x))₂Te₄ bulks and thin flakes, revealing intrinsic magnetic topological insulator phase in the phase diagram.

Bo Chen
Fucong Fei
Baigeng Wang
ResearchOpen Access02 Oct 2019
Nature Communications

Volume: 10, P: 1-8
Genome-wide in vivo CRISPR screens identify GATOR1 complex as a tumor suppressor in Myc-driven lymphoma

Identifying genes involved in MYC-driven lymphoma reveals therapeutic vulnerabilities. Here, the authors show by using CRISPR knockout screens in primary cells in vivo that the GATOR1 complex suppresses MYC-driven lymphomagenesis, and that GATOR1-deficient lymphomas are sensitive to mTOR inhibitors.

Margaret A. Potts
Shinsuke Mizutani
Marco J. Herold
ResearchOpen Access21 Aug 2025
Nature Communications

Volume: 16, P: 1-14
Achieving flexible fairness metrics in federated medical imaging

Achieving fairness while preserving privacy in medical imaging tasks remains a significant challenge. Here, the authors present and comprehensively evaluate a federated learning framework to tackle both fairness and privacy issues, using a flexible regularization term to integrate multiple fairness criteria.

Huijun Xing
Rui Sun
Zhen Li
ResearchOpen Access08 Apr 2025
Nature Communications

Volume: 16, P: 1-12
Experimental observation of bulk nodal lines and electronic surface states in ZrB₂

Rui Lou
Pengjie Guo
Shancai Wang
ResearchOpen Access12 Sept 2018
npj Quantum Materials

Volume: 3, P: 1-7
Towards intrinsic charge transport in monolayer molybdenum disulfide by defect and interface engineering

Impurities in molybdenum disulfide are known to reduce charge mobility to below its intrinsic limit. Here, the authors demonstrate that impurities are associated with lattice defects and that a chemical route can repair sulfur vacancies and improve interface quality with a substrate, enhancing device performance.

Zhihao Yu
Yiming Pan
Xinran Wang
Research20 Oct 2014
Nature Communications

Volume: 5, P: 1-7
Two-dimensional quasi-freestanding molecular crystals for high-performance organic field-effect transistors

Inorganic two-dimensional atomic crystals exhibit a variety of unusual but practically useful properties. Here, the authors produce an organic counterpart, atomically smooth monolayers of a molecular crystal, and use this organic analogue of graphene in high-performance organic field-effect transistors.

Daowei He
Yuhan Zhang
Xinran Wang
Research21 Oct 2014
Nature Communications

Volume: 5, P: 1-7
Resorbable barrier polymers for flexible bioelectronics

Resorbable bioelectronic devices have potential as tools for monitoring physiological parameters, but short functional lifetimes have slowed translation. Here, the authors report succinate-based copolyesters with barrier properties able to extend the functional lifetime of devices.

Samantha M. McDonald
Quansan Yang
Matthew L. Becker
ResearchOpen Access11 Nov 2023
Nature Communications

Volume: 14, P: 1-12
Screening oral drugs for their interactions with the intestinal transportome via porcine tissue explants and machine learning

A machine-learning model trained on interactions between oral drugs and intestinal drug transporters obtained by modulating their expression in intact porcine tissue can be used to predict drug–transporter and drug–drug interactions.

Yunhua Shi
Daniel Reker
Giovanni Traverso
Research20 Feb 2024
Nature Biomedical Engineering

Volume: 8, P: 278-290
Correction to: The anti-cancer agent APR-246 can activate several programmed cell death processes to kill malignant cells

Zilu Wang
Huimin Hu
Andreas Strasser
Amendments and CorrectionsOpen Access24 Feb 2023
Cell Death & Differentiation

Volume: 30, P: 1096
Spatially organized cellular communities form the developing human heart

Combining single-cell RNA-sequencing with high-resolution multiplexed error-robust fluorescence in situ hybridization reveals in detail the cellular interactions and specialization of cardiac cell types that form and remodel the human heart.

Elie N. Farah
Robert K. Hu
Neil C. Chi
ResearchOpen Access13 Mar 2024
Nature

Volume: 627, P: 854-864
The glycosylation design space for recombinant lysosomal replacement enzymes produced in CHO cells

Lysosomal replacement enzymes are taken up by cell surface receptors that recognize glycans, the effects of different glycan features are unknown. Here the authors present a gene engineering screen in CHO cells that allows custom N-glycan-decorated enzymes with improved circulation time and organ distribution.

Weihua Tian
Zilu Ye
Zhang Yang
ResearchOpen Access30 Apr 2019
Nature Communications

Volume: 10, P: 1-13
Surface protein imputation from single cell transcriptomes by deep neural networks

Cell-surface proteins serve as phenotypic cell markers and in many cases are more indicative of cellular function than the transcriptome. Here, the authors introduce a transfer learning framework to impute surface protein abundances from scRNA-seq data.

Zilu Zhou
Chengzhong Ye
Nancy R. Zhang
ResearchOpen Access31 Jan 2020
Nature Communications

Volume: 11, P: 1-10
Field-free spin-orbit torque-induced switching of perpendicular magnetization in a ferrimagnetic layer with a vertical composition gradient

Switching of ferrimagnets by current-induced spin-orbit torque is promising for spintronics, due to their high-speed dynamics and small macroscopic magnetization. Switching of perpendicularly magnetized materials, however, requires a bias field for symmetry breaking. Here, Zheng et al demonstrate field-free current-induced switching of perpendicular ferrimagnets, using a compositional gradient-driven Dzyaloshinskii–Moriya interaction.

Zhenyi Zheng
Yue Zhang
Pedram Khalili Amiri
ResearchOpen Access27 Jul 2021
Nature Communications

Volume: 12, P: 1-9
Specific glycine-dependent enzyme motion determines the potency of conformation selective inhibitors of threonyl-tRNA synthetase

Crystal structures and molecular dynamics simulations reveal that a critical glycine residue dominates the motion of threonyl-tRNA synthetase and the sensitivity of the enzyme to conformation selective inhibitors.

Hang Qiao
Zilu Wang
Pengfei Fang
ResearchOpen Access16 Jul 2024
Communications Biology

Volume: 7, P: 1-13
Mechanical sensing protein PIEZO1 controls osteoarthritis via glycolysis mediated mesenchymal stem cells-Th17 cells crosstalk

Yikun Zhou
Mingzhao Li
Ruili Yang
ResearchOpen Access01 Apr 2025
Cell Death & Disease

Volume: 16, P: 1-16
Data denoising with transfer learning in single-cell transcriptomics

SAVER-X trains a deep neural network for transfer learning that improves the quality of scRNA-seq data using prior information learnt from existing public studies.

Jingshu Wang
Divyansh Agarwal
Nancy R. Zhang
Research30 Aug 2019
Nature Methods

Volume: 16, P: 875-878
Author Correction: A consensus protocol for functional connectivity analysis in the rat brain

Joanes Grandjean
Gabriel Desrosiers-Gregoire
Andreas Hess
Amendments and Corrections18 Apr 2023
Nature Neuroscience

Volume: 26, P: 1127-1128
The disrupted jet stream and its influence on flight time during solar proton events

Xiaoheng Xu
Yi Wang
Xiaoxing Zhu
ResearchOpen Access02 Jul 2025
Scientific Reports

Volume: 15, P: 1-14
A consensus protocol for functional connectivity analysis in the rat brain

The authors pooled resources to identify best practices and develop a new standardized protocol for estimating functional connectivity in rats with magnetic resonance imaging.

Joanes Grandjean
Gabriel Desrosiers-Gregoire
Andreas Hess
Research27 Mar 2023
Nature Neuroscience

Volume: 26, P: 673-681
Numerical study on bearing performance of rock socketed pile anchored by inclined anchors under uplift and horizontal combined load

Zilu Xie
Zengzhen Qian
Jun Duan
ResearchOpen Access16 Aug 2025
Scientific Reports

Volume: 15, P: 1-21
A cross-sectional study of clinical characteristics and risk factors for hand eczema in the general Chinese population

Zilu Qu
Qian Jiang
Feng Hu
ResearchOpen Access29 Nov 2024
Scientific Reports

Volume: 14, P: 1-9
Branched-chain amino acid transaminase 1 confers EGFR-TKI resistance through epigenetic glycolytic activation

Tao Zhang
Zilu Pan
Hua Xie
ResearchOpen Access15 Aug 2024
Signal Transduction and Targeted Therapy

Volume: 9, P: 1-17
Author Correction: Experimental observation of bulk nodal lines and electronic surface states in ZrB₂

Rui Lou
Pengjie Guo
Shancai Wang
Amendments and CorrectionsOpen Access12 Oct 2018
npj Quantum Materials

Volume: 3, P: 1
Impairment of theta oscillations in the hippocampal CA1 region may mediate age-dependent movement alternations in the 5xFAD mouse model of Alzheimer’s disease

Hong Ni
Zhongzhao Guo
Deheng Wang
ResearchOpen Access31 Mar 2025
Scientific Reports

Volume: 15, P: 1-18
Reflectance confocal microscopy for plaque psoriasis therapeutic follow-up during an anti-interleukin-17A monoclonal antibody: an observational study

Qian Jiang
Zilu Qu
Feng Hu
ResearchOpen Access02 Jul 2024
Scientific Reports

Volume: 14, P: 1-8
The anti-cancer agent APR-246 can activate several programmed cell death processes to kill malignant cells

Zilu Wang
Huimin Hu
Andreas Strasser
ResearchOpen Access04 Feb 2023
Cell Death & Differentiation

Volume: 30, P: 1033-1046
Umbilical cord blood platelet lysate preserves myofibroblast migration and mitigates hyperoxic lung injury

Xueyu Chen
Bingchun Lin
Chuanzhong Yang
Research10 Oct 2025
Pediatric Research

P: 1-8
SeparaFill: Two generators connected mural image restoration based on generative adversarial network with skip connect

Chaohui Lv
Zilu Li
Jin Zheng
ResearchOpen Access31 Aug 2022
Heritage Science

Volume: 10, P: 1-13
Effects of different conditioning regimens on HLA-mismatched microtransplantation and changes in fine immune indices in acute myeloid leukaemia

Zheng Hanxue
Meng Zilu
Li Lijuan
ResearchOpen Access20 Aug 2024
Scientific Reports

Volume: 14, P: 1-12
Frontostriatal regulation of brain circuits contributes to flexible decision making

Ying Duan
Zilu Ma
Yihong Yang
ResearchOpen Access14 Feb 2025
Neuropsychopharmacology

Volume: 50, P: 1156-1166
High expression of PPP1CC promotes NHEJ-mediated DNA repair leading to radioresistance and poor prognosis in nasopharyngeal carcinoma

Ping Feng
Ying Wang
Yunfei Xia
Research08 Apr 2024
Cell Death & Differentiation

Volume: 31, P: 683-696
Deficiency of SIAH1 promotes the formation of filopodia by increasing the accumulation of FASN in liver cancer

Zhiyi Liu
Qinghe Hu
Renhao Wang
ResearchOpen Access29 Jul 2024
Cell Death & Disease

Volume: 15, P: 1-17
Genome-wide CRISPR screening identifies a role for ARRDC3 in TRP53-mediated responses

John E. La Marca
Brandon J. Aubrey
Gemma L. Kelly
ResearchOpen Access14 Dec 2023
Cell Death & Differentiation

Volume: 31, P: 150-158
Needle-array to Plate DBD Plasma Using Sine AC and Nanosecond Pulse Excitations for Purpose of Improving Indoor Air Quality

Li Zhang
Dezheng Yang
Li Jia
ResearchOpen Access29 Apr 2016
Scientific Reports

Volume: 6, P: 1-14
IGF-1/IGF-1R/hsa-let-7c axis regulates the committed differentiation of stem cells from apical papilla

Shu Ma
Genxia Liu
Jinhua Yu
ResearchOpen Access11 Nov 2016
Scientific Reports

Volume: 6, P: 1-12
Lymphoma cells lacking pro-apoptotic BAX are highly resistant to BH3-mimetics targeting pro-survival MCL-1 but retain sensitivity to conventional DNA-damaging drugs

Sarah T. Diepstraten
Savannah Young
Gemma L. Kelly
ResearchOpen Access08 Feb 2023
Cell Death & Differentiation

Volume: 30, P: 1005-1017
Multilevel regulation of Wnt signaling by Zic2 in colon cancer due to mutation of β-catenin

Zhengshui Xu
Jianbao Zheng
Junhui Yu
ResearchOpen Access07 Jun 2021
Cell Death & Disease

Volume: 12, P: 1-13
Flow cytometric single cell-based assay to simultaneously detect cell death, cell cycling, DNA content and cell senescence

Elizabeth Lieschke
Zilu Wang
Andreas Strasser
Research09 Mar 2022
Cell Death & Differentiation

Volume: 29, P: 1004-1012
BH3 mimetic drugs cooperate with Temozolomide, JQ1 and inducers of ferroptosis in killing glioblastoma multiforme cells

Diane Moujalled
Adam G. Southon
Andreas Strasser
Research24 Mar 2022
Cell Death & Differentiation

Volume: 29, P: 1335-1348
Cleavage of GSDME by caspase-3 determines lobaplatin-induced pyroptosis in colon cancer cells

Junhui Yu
Shan Li
Jianbao Zheng
ResearchOpen Access25 Feb 2019
Cell Death & Disease

Volume: 10, P: 1-20
MRD positivity was the poor prognostic factor for adverse-risk AML patients with allogeneic hematopoietic stem cell transplantation: a multicenter TROPHY study

Yang Cao
Wenxuan Huo
Xiaodong Mo
CorrespondenceOpen Access17 Jan 2024
Blood Cancer Journal

Volume: 14, P: 1-6
Loss of TRP53 reduces but does not overcome dependency of lymphoma cells on MCL-1

Brandon J. Aubrey
Margs S. Brennan
Gemma L. Kelly
Correspondence28 Jan 2022
Cell Death & Differentiation

Volume: 29, P: 1074-1076
Association between angiotensin-converting enzyme inhibitors and the risk of lung cancer: a systematic review and meta-analysis

Zhenchao Wu
Taikang Yao
Ning Shen
ReviewsOpen Access17 Nov 2022
British Journal of Cancer

Volume: 128, P: 168-176
Should mutant TP53 be targeted for cancer therapy?

The attributes proposed for mutant TP53 to drive tumour development and possible approaches to target them. Model depicting the three attributes by which mutant TP53 is thought to promote tumour development: loss-of-function (LOF), dominant negative effects (DNE) over wt TP53 and neomorphic gain-of-function (GOF) effects.

Zilu Wang
Andreas Strasser
Gemma L. Kelly
Reviews24 Mar 2022
Cell Death & Differentiation

Volume: 29, P: 911-920

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