Neuroendocrinology articles from across Nature Portfolio

The peptide hormone Capa is responsible for regulating extracellular fluid Ca²⁺ levels in the fruit fly Drosophila melanogaster.

Studies in mice show that acute stress activates hyperglycaemia via activation of a medial amygdala–ventral hypothalamic circuit that controls glucose metabolic responses in the liver, independently of adrenal and pancreatic hormones.

Transient neonatal kisspeptin blockade disrupts sex-specific testosterone surge, altering social behavior, vocal communication, and hormonal balance throughout life, revealing a critical role for early kisspeptin signaling in long-term social behavior.

Pituitary gonadotrophs secrete LH and FSH, regulating gonadal function. Here authors show that in the mouse pituitary most gonadotrophs originate from postnatal stem cells, while a minor population of cells born in the embryo persist.

A study in Science reports that intestinal innate lymphoid cells migrate to the pancreas in response to low blood glucose levels to promote glucagon production.

Independent of its appetite- and body weight-modulating effects, the hormone asprosin activates its receptor PTPRD at cerebellar Purkinje neurons to enhance thirst and maintain fluid homeostasis. Surprisingly, this has no effect whatsoever on Purkinje neuron-mediated motor coordination and learning.